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Clinical Trials for Chronic Pain

• Esketamine as Treatment for Chronic Pain Due to Endometriosis: a RCT Study
• Precision Medicine for Nociception, Sngception and Proprioception.
• Perioperative Vitamin C to Reduce Persistent Pain After Total Knee Arthroplasty
• Managing Chronic Tendon Pain by Metformin
• Reducing Perioperative Oxidative Stress to Prevent Postoperative Chronic Pain Following Total Knee Arthroplasty
• Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Diabetic Polyneuropathy
• Efficacy and Tolerability of AP707 in Patients With Chronic Back Pain
• Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Central Neuropathy of Any Genesis
• Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Traumatic or Post-operative Peripheral Neuropathy
• Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Diabetic Polyneuropathy
• Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Back Pain
• Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Central Neuropathy of Any Genesis
• Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Traumatic or Post-operative Peripheral Neuropathy
• Managing Opioid Related Sleep Apnea With Acetazolamide
• Analgesic Effectiveness of Capsaicin 8% Cutaneous Patch in Children
• A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain
• Aromatherapy and Pain
• Dexmedetomidine and Morphine as Adjuvants to US Guided Erector Spinae Plane Blocks in Elective Thoracic Surgeries
• A Helping Osteoarthritis Patients to Walk With NSAID
• Culturally Adapted Mobile Treatment of Chronic Pain in Adolescent Survivors of Pediatric Bone Sarcoma
• Opioid Sparing Anesthesia in Cervical Spine Surgery
• Multiple Dose Study of Safety and Pharmacokinetics of MEDI0618 in Healthy Volunteers
• A Randomized, Controlled Study of Repeat Dose Sustained Release Lidocaine for Treatment of Chronic Scrotal Pain
• Screening Trial for Pain Relief in Schwannomatosis (STARFISH)
• US-Guided Serratus Anterior Plane Block Versus Thoracic Epidural in Patients Undergoing Thoracotomy
• A Chronic Pain Master Protocol (CPMP): A Study of LY3857210 in Participants With Diabetic Peripheral Neuropathic Pain (NP05)
• A Chronic Pain Master Protocol (CPMP): A Study of LY3857210 In Participants With Osteoarthritis Pain
• Immune Mechanisms of Vitamin D to Reduce Chronic Pain After Burn
• Continuous Sciatic Nerve Block vs Epidural Analgesia in Lower Limb Amputation for Postoperative Pain
• STTEPP: Safety, Tolerability and Dose Limiting Toxicity of Lacosamide in Patients With Painful Chronic Pancreatitis
• Comparative Study on the Effect of Quadratus Lumborum Block Versus Intrathecal Morphine on the Incidence of Chronic Pain Post Caesarean Section in a University Hospital of Middle-income Country
• Opioid Sparing Anesthesia in Lumbar Spine Surgery
• Standardized Natural Psilocybin-assisted Psychotherapy for Tapering of Opioid Medication
• The Impact of Esmolol Administration on Postoperative Recovery
• Understanding Pain Mechanisms in Knee Osteoarthritis
• Caudal Epidural Prolotherapy Versus Steroids in Failed Back Surgery Syndrome
• Single Ascending Dose or 14-day Study With AFA-281 in Healthy Volunteers
• Psilocybin Combined With Multidisciplinary Palliative Care in Demoralized Cancer Survivors With Chronic Pain
• Intravenous Lidocaine on Chronic Pain and Long-term Quality of Life in Patients Undergoing Hepatocellular Carcinoma Resection
• Project 1 Aim 2, Adaptations of the Brain in Chronic Pain With Opioid Exposure
• A Double-blind, Randomized, Placebo-controlled Comparison of TAU vs Split Daily Methadone Dosing for Pain Among MMP
• Frequency of Piriformis Syndrome:Does the Presence of One Pathology Rule Out the Other?
• The Effect of Subcutaneous Injection of Botulinum Toxin A on Chronic Wound Pain in Lower Extremities
• Study on the Efficacy of Infiltration of Upper Cluneal Nerves in Chronic Pain Related to Cluneal Syndrome
• True Functional Restoration and Analgesia in Non-Radicular Low Back Pain
• Effectiveness of the Sana Device on Fibromyalgia Symptoms
• Dexmedtemodine or Hyalase : Which of Them Can Augment Lumbar Epidural Steroid Injection in Failed Back Surgery Patients. A Randomized Clinical Trial
• Mechanism of Analgesic Effect on Prolonged Continuous Theta Burst Stimulation
• Opioid-Sparing Effect of Oral Cannabinoids
• To Evaluate the Food Effect and the Absorption Profile of Ibuprofen Modified-Release Tablets 800 mg
• RCT, Blinded, 2-Arm Efficacy Study of IP and Placebo in Patients With Chronic Pain Related to Osteoarthritis of the Knee
• The Role of Brain Dopamine in Chronic Pain
• Dexmedetomidine Versus Hyalase Treatment of Carpal Tunnel Syndrome
• Trans-foraminal Lumbar Epidural Injection of Dexmedetomidine Against Magnesium Sulfate When Combined With Dexamethasone in Uni-lateral Lower Limb Radicular Pain. Multi-centeric Comparative Study
• Morphine vs Sufentanil PCA: Same Same or Different?
• Opioid-free Anesthesia in Thyroidectomies
• Naldebain for Control of Post-Cesarean Section Pain
• Chronic Pain Master Protocol (CPMP): A Study of LY3526318 in Participants With Diabetic Peripheral Neuropathic Pain
• Efficacy of Compound Betamethasone Injection Combined With Ropivacaine in Ultrasound-guided Thoracic Paravertebral Nerve Block for Chronic Post-thoracotomy Pain
• Opioid Free Anaesthesia-Analgesia Strategy on Surgical Stress and Immunomodulation in Elective VATS-Lobectomy for NSCLC
• Gabapentin & Ketamine for Prevention/Treatment of Acute/Chronic Pain in Locally Advanced Head and Neck Cancer
• Precision Medicine for Sng/Pain Control
• Transforaminal Epidural Platelet Rich Plasma Versus Epidural Steroid Injection for Lumbosacral Radicular Pain
• Efficacy and Safety of Canadá Association in the Treatment of Chronic Pain
• Randomized Trial of Buprenorphine Microdose Inductions During Hospitalization
• Evaluation of Botox Treatment on Chronical Scrotal Pain
• Using Oral Valacyclovir to Treat Patients With Refractory IC/BPS
• Opioid-free Anesthesia in Laparoscopic Cholecystectomies
• Chronic Pain Master Protocol (CPMP): A Study of LY3526318 in Participants With Chronic Low Back Pain
• Reconsolidation Therapy With Propranolol as a Treatment for Chronic Pain
• Chronic Pain Master Protocol (CPMP): A Study of LY3526318 in Participants With Osteoarthritis
• Effects of Multimodal Analgesia on Serum MCP-1, BDNF, and MiRNA-124 in Hysterectomy Surgery
• Psilocybin-facilitated Treatment for Chronic Pain
• A Novel Medical System for Quantitative Diagnosis and Personalized Precision Botulinum Neurotoxin Injection in Chronic Pelvic Pain Management
• Uncovering Neural and Immune Mechanisms of Chronic Pain in Post Treatment Lyme Syndrome
• The Use of Venlafaxine in Reducing Pain in Primary Total Knee Replacement
• Integrated Supported Biopsychosocial Self-Management for Back Related Leg Pain
• Intra-articular Analgesia Versus Adductor Canal Block for Arthroscopic Knee Surgery
• Ozone Therapy in Patients With Diabetic Neuropathy
• Intravenous(IV) vs. Erector Spinae Plane Blocks in Cardiac Surgery
• Propolis Versus Calcium Hydroxide on Post-Operative Pain in Patients With Necrotic Pulp
• Brain Mechanisms Supporting Cannabis-induced Pain Relief
• A Study of Cybis™ 10:25 THC:CBD Oil in Adults With Chronic Back/Neck Pain
• Dexmedetomidine Versus Triamcinolone Treatment of Carpal Tunnel Syndrome
• Novel Use of Probenecid to Alleviate Symptoms of Opioid Withdrawal
• Evaluating the Efficacy of Intranasal Oxytocin on Chronic Pain
• Chronic Pain Master Protocol (CPMP): A Study of LY3556050 in Participants With Chronic Low Back Pain
• Prevention of Persistent Pain With LidocAine iNfusions in Breast Cancer Surgery (PLAN)
• Chronic Pain and Conditioned Pain Modulation After on Line-behavioral Approach
• Opioid-free Anesthesia With a Mixture of Dexmedetomidine-lidocaine-ketamine
• Morphine Versus Ketamine as Adjuvants in Paravertebral Blocks
• Neural Mechanisms of Immersive Virtual Reality in Chronic Pain
• Naldebain for Pain Management of Laparoscopic Cholecystectomy
• Chronic Widespread Pain in HIV: Novel Mechanisms and Therapeutics
• Pain, Learning, and Nocebo
• The Study of Hemp Oil CBD for Evaluation of Efficacy and Safety in Treatment of Pain, Anxiety and Insomnia Management
• Tapentadol Versus Tramadol Analgesia Post Cardiac Surgery
• Chronic Musculoskeletal Pain
• Chronic Pain Master Protocol (CPMP): A Study of LY3556050 in Participants With Diabetic Peripheral Neuropathic Pain
• A Comparison of Gabapentin and Ketamine in Acute and Chronic Pain After Inguinal Hernia Repair
• Injection of Dorsal Scapular n at Different Levels, Dose it Make Difference?
• Latent Aging Mechanisms in Pain and Sleep
• Safety, Tolerability, Effectiveness, and Pharmacokinetic Data in Opioid-experienced Children
• Improving Pain Management Via Spinal Cord Stimulation and Blood Pressure Reduction
• Psychobiological Mechanisms Underlying Chronic Pain
• Naldebain for Pain Control After Bariatric Surgery
• Study of Efficacy and Safety of SAF312 Eye Drops in Subjects With Post-operative Corneal Induced Chronic Pain (CICP)
• Lidocaine and Magnesium and Ketamine in Gynecological Surgery
• Effect of Tramadol Versus Morphine on PD1 and PD1-ligand in Patients With Chronic Cancer Pain
• Cannabidiol in Opioid Use Disorder and Chronic Pain
• Botulinum Toxin A as Treatment for Chronic Postsurgical Pain Following Lung Cancer Surgery
• HOPE Consortium Trial to Reduce Pain and Opioid Use in Hemodialysis
• Intradiscal Platelet Rich Plasma
• Paracetamol Discontinuation in the Elderly After Long-term Consumption
• Bacteriostatic Normal Saline Versus Lidocaine for Intradermal Anesthesia
• The Effect of Chronic Pain on Delay Discounting in Methadone Patients
• Suboxone User Perioperative Early Referral and Enhanced Recovery After Surgery- Orthopaedic Trauma Surgery Population
• Stanford Pragmatic Effectiveness Comparison
• PET/MRI in the Diagnosis of Pediatric Chronic Pain
• Apply the PD Model of Peripheral Oxytocin Action to a Multimodal Stimulus
• Magnesium Sulphate to Bupivicaine in Serratus Anterior Plane Block in Modified Radical Mastectomy
• Gabapentin and Tizanidine for Insomnia in Chronic Pain
• Generate and Test the Reliability of a PD Model of OXT on Pupillary Hippus as a Measure of CNS Activity
• Pain Response Evaluation of a Combined Intervention to Cope Effectively
• Pain Reduction and Changes in Upper Limb Function Produced by an Ibuprofen Treatment in Carpal Tunnel Syndrome.
• Ketamine Infusion for Comorbid PTSD and Chronic Pain
• COmparison Erect SPINE in Cardiac Surgery (COESPINE)
• Overlapping Buprenorphine Initiation (in Opioid Physical Dependence)
• Perioperative Ketamine in Opioid-Tolerant Patients Undergoing Lumbar Spine Surgery
• Preoperative Paravertebral Block in Cancer Surgery of the Lung
• Effects of Thoracic Erector Spinae Plane Blockade on Acute and Chronic Pain After Video Assisted Thoracoscopic Surgery (VATS)
• A Study of the Safety, Tolerability and Pharmacokinetics of MEDI0618 in Healthy Volunteers
• The Influence of TAP Block in the Control of Postoperative Pain After Laparotomy for Gynecological Procedures
• A Study to Evaluate the Safety and Pharmacokinetics of CNTX-6016 in Healthy Subjects
• Dosing Intervals of Opioid Medication for Chronic Pain
• Ambulatory Infusions of Lidocaine and Ketamine for Management of Chronic Pain
• Duloxetine Combined With Intra-articular Injection of Corticosteroid and Hyaluronic Acid Reduces Pain in the Treatment of Knee Osteoarthritis Patients
• Low Dose Naltrexone for Chronic Pain in Osteoarthritis and Inflammatory Arthritis
• Safety, Tolerability, and Pharmacokinetics of HSK21542 in Healthy Volunteers
• Effects of IM Oxytocin on Pupil Diameter and HRV
• Post-market, Randomized, Controlled, Prospective Study Evaluating Intrathecal Pain Medication (IT) Versus Conventional Medical Management (CMM) in the Non-cancer, Refractory, Chronic Pain Population
• St. PETERsburg Pain and Alcohol Intervention With Naltrexone and Gabapentin
• Pain Neuroscience Education in Patients With Fibromyalgia
• Mechanisms of CBD for Chronic Pain
• Ketamine to Improve Recovery After Cesarean Delivery - Part 1
• Cannabidiol, Morphine, Pain
• Sustained Release Lidocaine for Treatment of Scrotal Pain
• Chronic Pain and Functional Prognosis After Total Knee Replacement: Continuous Locoregional Analgesia by Catheter to the Femoral Triangle Versus Tissue Infiltration as Part of an Improved Rehabilitation After Surgery Approach
• Sublingual Cannabidiol for Chronic Pain
• Buprenorphine Transdermal Patches Pharmacokinetic Study
• Phenol Neurolysis of Genicular Nerves for Chronic Knee Pain
• Outcomes Mandate National Integration With Cannabis as Medicine for Prevention and Treatment of COVID-19
• Effects of Intramuscular Oxytocin on Sensory Function in Healthy Volunteers With Ultraviolet Burn Injury to the Skin
• PK Sampling After IV Oxytocin and Effects on Sensory Function in Healthy Volunteers
• Cabergoline for the Treatment of Chronic Pain Due to Endometriosis
• Ketamine's Effect Changes the Cortical Electrophysiological Activity Related to Semantic Affective Dimension of Pain
• Sulfasalazine in Decreasing Opioids Requirements in Breast Cancer Patients
• Non-Opioid Pramipexole and Pain
• Effect of Safinamide on Parkinson's Disease Related Chronic Pain
• A Study Using fMRI Imaging to Evaluate the Effect of NKTR-181 on Brain Activity in Healthy, Non-physically Dependent Recreational Opioid Users.
• A Placebo-Controlled, Two-Part Study, Oral Dose to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of CNTX-6970 in Healthy Subjects
• Dronabinol Opioid Sparing Evaluation (DOSE) Trial
• A Clinical Study in Healthy Women Which Aims to Explore the Intestinal Uptake of Two Different Tablets of GRTA9906 Into the Body and the Effect of Food on it
• A Clinical Study in Healthy Adults Who Sometimes Take Drugs for Pleasure to Investigate the Safety and Tolerability of GRT0151Y and to Find Out Which Single Dose of the Compound is Maximally Tolerated
• High-Dose Steroid for Hip Arthroplasty Patients Expected to Have Postoperative Pain
• High-Dose Steroid for Knee Arthroplasty Patients Expected to Have Postoperative Pain
• Embrace TDD: Post-Market Study to Evaluate Intrathecal Morphine as an Alternative to Systemic Opioids for Chronic Pain
• Strategies to Improve Pain and Enjoy Life
• Local Injection of Ozone Versus Methylprednisolone Acetate in Carpal Tunnel Syndrome of Scleroderma Patients
• Cannabis Vs Opioids Pain Management Objective Testing Comparisons
• Exploratory Evaluation of [11C]-NOP46
• Lidocaine Infusion for Pain After Herniotomy
• Lidocaine Infusion for Postthoracotomy Pain Syndrome
• Omnitram Safety and Efficacy in the Treatment of Diabetic Neuropathy
• Para-vertebral Dexmedetomidine and the Incidence of Postoperative Chronic Pain
• Ultrasound-guided Genicular Nerve Block With Phenol for the Treatment of Chronic Pain Due to Knee Osteoarthritis
• Perineural Platelet-rich Plasma for Diabetic Neuropathy Pain
• Use of Xtampza ER to Overcome Difficulties in Swallowing Opioid Pills
• PET/MRI in the Diagnosis of Chronic Pain
• Comparing Effectiveness of Duloxetine and Desipramine in Patients With Chronic Pain: A Pragmatic Trial Using Point of Care Randomization
• Cannabis Oil for Pain Effectiveness
• Accuracy and Efficacy of Trazodone (Desyrel) on Sleep Quality and Pain Management of TMD Patient
• Buspirone for Opioid Tapering
• Ketamine's Efficiency in the Treatment of Chronic Pain: Kynurenin Pathway
• Ketamine Sickle Cell Disease
• Radiofrequency Thoracic Sympathectomy for Chronic Postmastectomy Pain; Randomized Placebo Controlled Study
• Prevention of Persistent Opioid Use in Mothers
• Bonipar for Acute and Chronic Musculoskeletal Pain
• Evaluating the Safety, Tolerability, and Pharmacokinetics of BIIB095 in Healthy Participants
• Effect of Intrathecal Morphine on Chronic Pain After Elective Caesarean Section
• Hyperalgesia, Persistent Pain, and Fentanyl Dosing in On-Pump Coronary Artery Bypass Grafting
• The Economic and Cognitive Effects of Pain Reduction
• OTR Tablet 10 mg Fasted-state Bioequivalence Study
• OTR Tablet 40 mg Fed-state Bioequivalence Study
• OTR Tablet 40 mg Fasted-state Bioequivalence Study
• Cognitive Function and Addiction Under Opioid Tapering
• QLB and Laparoscopic Nephrectomy, Postoperative Pain and Recovery
• Safety and Efficacy of Medical Cannabis Oil in the Treatment of Patients With Chronic Pain
• Study on the Effects of Intravenous Dexmedetomidine on Pain in Patients Undergoing Elective Spinal Surgery
• Altering The Transition From Acute to Chronic Pain (ATTAC-Pain)
• Vitamin D and n-3 Polyunsaturated Fatty Acids (PUFAs) to Prevent Chronic Pain Following Major Thermal Burn Injury
• Ketamine With Multilevel Paravertebral Block for Post Video-assisted Thoracic Surgery Pain
• Efficacy and Safety Study of Gabapentin as add-on to Morphine in Paediatric Patients Affected by Chronic Pain
• Interscalene Block Versus Superior Trunk Block
• Effect of Duloxetine on Opioid Use After Total Knee Arthroplasty
• The Effect of Gabapentin Used as a Preemptive to the Emergence and Development Chronic Neuropathic Pain in Patients After Spinal Cord Trauma
• Effect of Combined Morphine and Duloxetine on Chronic Pain
• Radiofrequency Neurotomy In Relieving Chronic Knee Pain
• Study To Assess Safety, Tolerability And PK Of ATB-346 In Healthy Subjects
• Treatment of Chronic Pain With Cannabidiol (CBD) and Delta-9-tetrahydrocannabinol (THC)
• Use of PET/MR Imaging in Chronic Pain
• Targin® for Chronic Pain Management in Patients With Spinal Cord Injury
• Median Nerve Hydro-dissection Using Single Injection of Hyalase as a Novel Treatment of Carpal Tunnel Syndrome
• Preoperative Gabapentin for Chronic Pain After Thoracotomy (GABATHOMIE).
• Evaluating the Role of Neuroinflammation in Low Back Pain
• Prevention of Post Mastectomy With Intraoperative Ketamine
• Efficacy and Safety of IGN-ES001 in Chronic Widespread Pain With or Without Fibromyalgia
• Veterans' Pain Care Organizational Improvement Comparative Effectiveness Study
• Implication of Two Doses of O2-O3 Upon the Pain Alleviation in Patients With Low Back Pain
• Low Dose Naltrexone for Chronic Pain From Arthritis
• Lidocaine Infusions for Chronic Pain in Children
• Impact of Polymorphisms of OCT2 and OCTN1 on the Kinetic Disposition of Gabapentin in Patients Undergoing Chronic Use
• Does Subacromial Injection With Glutamate Receptor Antagonist, Ketamine, Attenuate Pain in Rotator Cuff Tendinopathy?
• Anesthesia for Pain After Ankle Fracture Surgery
• Buprenorphine (CAM2038) in Subjects With a Recent History of Moderate to Severe Chronic Low Back Pain
• Ketamine and Magnesium in Post-operative Pain Control in Patients Treated With Opioids
• Paravertebral Morphine Versus Dexmedetomidine on Acute and Chronic Postmastectomy Pain
• Subdissociative Dose Ketamine for Treatment of Acute Pain in Subjects With Chronic Pain
• Evaluating the Efficacy of Intranasal Oxytocin Among Individuals With Persistent Pain
• Patient Controlled Intrathecal Analgesia With Bupivacaine for Chronic Low Back Pain
• OXN PR Tablet 5/2.5 mg and20/10 mg PK Study in Chinese Moderate to Severe Chronic Non-malignant Patients
• Intra-operative Lidocaine Infusion in Preventing CPSP Post VATs
• Epidural Dexamethasone Versus Betamethasone for Treatment of Lumbosacral Radiculalgia
• Does Intraoperative Methadone Prevent Postoperative Pain in Bariatric Surgery?
• Efficacy of Opioid-free Anesthesia in Reducing Postoperative Pain in Chronic Pain Patients Undergoing Spinal Surgery
• Neurologic Signatures of Chronic Pain Disorders
• Discontinuation vs Continuation of Long-term Opioid Therapy in Suboptimal and Optimal Responders With Chronic Pain
• Discontinuation From Chronic Opioid Therapy For Pain Using a Buprenorphine Taper
• Intraoperative Ketamine on Chronic Pain After Mastectomy
• Study to Compare Gabapentin to Tramadol in Children With Chronic Neuropathic or Mixed Pain
• Pectoral Nerves Blocks for Chronic Pain
• Phase II Pharmacokinetics Study of CAM2038
• Efficacy of Ultra-micronized Palmitoylethanolamide (Um-PEA) in Geriatric Patients With Chronic Pain
• Effectiveness of Ultrasound Guided Adductor Canal Block on Chronic Pain in Knee Osteoarthritis
• Uncovering Neural and Immune Mechanisms of Chronic Pain in Post Treatment Lyme Syndrome
• Investigation of Cannabis for Chronic Pain and Palliative Care
• Shifting Pain Modulation From Pro-to Anti-nociceptive
• Effects of Perioperative Intravenous Lidocaine and Ketamine on Acute and Chronic Pain After Open Nephrectomy
• The Progression From Dysmenorrhoea to Chronic Pelvic Pain
• Intra-Articular 0.5 % Lidocaine Injection for Osteoarthritis
• Long Term Safety and Efficacy Study of Tanezumab in Subjects With Osteoarthritis of the Hip or Knee
• Influence of Anesthetic Technique on Acute and Chronic Neuropathic Pain
• Gulf War Illness Inflammation Reduction Trial
• Fascia Iliaca Compartment Block in Acute and Chronic Pain Management in Hip Fracture Patients
• Reduced Opioid Analgesic Requirements Via Improved Endogenous Opioid Function
• Ketamine as Adjunctive Analgesic With Bupivacaine in Paravertebral Analgesia for Breast Cancer Surgery
• Effect of Locally Administered Morphine and Bupivicaine on Acute and Chronic Postmastectomy Pain
• The Effects of TAP Block on Postsurgical Pain After Minimally Invasive Partial Nephrectomy:
• Study of the Treatment of Experimental Pain in Buprenorphine Maintained Persons With Chronic Musculoskeletal Pain
• Long-Term Safety and Tolerability Study of NKTR-181 in Subjects With Chronic Low Back Pain or Chronic Non-Cancer Pain
• Efficacy and Safety Study of NKTR-181 in Opioid-Naive Subjects With Low Back Pain
• A Study to Examine the Safety, Pharmacokinetics and Pharmacodynamics of AMG 403 in Healthy Subject
• Development and Evaluation of a Methadone Protocol for Severe Chronic Pain Management
• Assessment of the Safety and Efficacy of 3VM1001 Cream for Treatment of Chronic Pain Caused by Knee Osteoarthritis.
• Open-Label Safety and PK Study of ER Hydromorphone Tablets in Opioid-Tolerant Pediatric Chronic Pain Patients
• Does Duloxetine Reduce Chronic Pain After Total Knee Arthroplasty?
• Ultra-low Dose Oral Ketamine for Chronic Pain in the Primary Care Setting
• A Comparison of Morphine and Morphine Plus Dexmedetomidine in Chronic Cancer Pain
• Evaluation of a Compliance Marker in Prescription Opioid Abusers With Chronic Pain
• Dexamethasone and Pain Following Total Knee Arthroplasty
• Genetic Determinants of Amitriptyline Efficiency for Pain Treatment - Part II
• Genetic Determinants of Amitriptyline Efficiency for Pain Treatment
• The Efficacy of CALPXT96™in Improving Sleep Quality in Patients With Chronic Non-cancer Pain
• Lidocaine Infusion for Chronic Pain in Opioid Dependent Patients
• Chronic Pain Risk Associated With Menstrual Period Pain
• Imaging Pain Relief in Osteoarthritis
• The Effect of an Additional Bolus Application in Patients With Intrathecal Opiate Administration - a Pilot Study
• Effect of Guanfacine on the Reversal of Opioid-induced Hyperalgesia (OIH)
• Metamizol for the Treatment of Neoplastic Chronic Pain
• Fentanyl Sublingual Spray for the Treatment of Acute Procedure-related Pain in a Monitored Setting
• Dexamethasone for Reduction of Post Thoracotomy Pain Syndrome
• Acetaminophen for Chronic Pain in Hysterectomy
• The Effect of Intraoperative Ketamine on Opioid Consumption and Pain After Spine Surgery in Opioid-dependent Patients
• Trigger-point Blockade in Persistent Pain After Laparoscopical Groin Hernia Repair
• Trigger-point Blockade in Persistent Pain After Open Groin Hernia Repair
• Minocycline to Reduce Pain After Carpal Tunnel Release
• Levobupivacaine Prolonged Wound Infusion for Postoperative Pain Relief After Breast Surgery
• Treatment of Chronic Pain From Osteoarthritis
• CORAL XT - Open-label Extension Trial of the CORAL Trial
• Remifentanil vs Fentanyl During Cardiac Surgery and Chronic Thoracic Pain
• Plasma Concentration of Ketamine and Norketamine .
• Chronic Pain and Vitamin D
• Ketamine in Robot-assisted Thyroidectomy
• CORAL - Cebranopadol Versus Morphine Prolonged-release in Patients With Chronic Moderate to Severe Pain Related to Cancer
• Cebranopadol Efficacy and Safety in Diabetic Patients Suffering From Chronic Pain Caused by Damage to the Nerves
• A Study of Duloxetine in Participants With Chronic Pain Due to Osteoarthritis in China
• The Effect of Adding Magnesium Sulfate to Standard Epidural and Interscalene Block in Treatment of Patients With Chronic Pain
• A Study to Explore the Influence of Two Opioid Pain Medications on Bacterial Composition in the Gut and Other Gastrointestinal Aspects
• Mechanistic Study of Duloxetine in Breast Cancer Patients With Chronic Pain
• Functional Neuroimaging in Fibromyalgia Patients Receiving tDCS
• Efficacy and Safety Study of Fentanyl Transdermal Patch for Treatment of Chronic Pain
• Neurosteroids as Novel Therapeutic Agents for Chronic Pain in OEF/OIF Veterans
• Patient Registry of Intrathecal Ziconotide Management(PRIZM)
• Buprenorphine vs. Opioid Dose Escalation Among Patients With Chronic Pain
• Testosterone Replacement for Male Opioid Agonist Maintained Patients
• A Study of IMC-1 In Patients With Fibromyalgia
• Increased Sensitivity to Pain Caused by Opioids in People Who Have Abused Prescription Opioids
• A Study to Assess the Improvement of Pain and Health-Related Quality of Life in Patients With Chronic Non-Malignant Pain Taking Tramadol Hydrochloride and Acetaminophen
• An Efficacy and Safety Study of Transdermal Therapeutic System (TTS)-Fentanyl in Thai Participants With Chronic Non-Malignant Pain
• An Interventional Study to Compare the Efficacy and Tolerability With Targin® in Non-malignant Chronic Pain (GLORY)
• Ketamine in Chronic Kid's (KiCK) Pain
• Efficacy and Tolerability of Lidocaine Plaster for Treatment of Long-term Local Nerve Pain
• Single-arm Study to Assess the Safety of Hydromorphone Hydrochloride by Intrathecal Administration
• Safety and Efficacy Study of Hydromorphone Hydrochloride by Intrathecal Administration
• Safety and Efficacy Study of GRT6005 in Patients With Osteoarthritis (OA) Knee Pain
• Analgesic Efficacy and Safety of V116517 in Subjects With Moderate to Severe Chronic Pain Due to Postherpetic Neuralgia (PHN)
• Analgesic Efficacy and Safety of V116517 in Subjects With Moderate to Severe Chronic Pain Due to Osteoarthritis (OA) of the Knee
• The Effectiveness and Tolerability of Fentanyl Matrix in Chronic Non-cancer Pain; Assessment of Patient's Pain Treatment Goal Achievement
• Effect of Guanfacine on Opioid-induced Hyperalgesia (OIH) and Tolerance
• Effectiveness of Gabapentin on Chronic Irritability in Neurologically Impaired Children
• Lidocaine and Prevention of Chronic Pain
• Abuse Potential Assessment of Intranasally Administered EMBEDA Compared To Morphine Sulfate Controlled Release And Placebo
• Clinical Trials With a Local Anesthetic Lozenge for the Treatment of Chronic Oral Pain
• A Research Study of an Investigational Drug ALO-02 (Oxycodone Hydrochloride and Naltrexone Hydrochloride) in Patients With Moderate to Severe Chronic Low Back Pain
• The Analgesic Efficacy of Δ9-THC (Namisol®) in Patients With Persistent Postsurgical Abdominal Pain
• Δ9-THC (Namisol®) in Chronic Pancreatitis Patients Suffering From Persistent Abdominal Pain
• The Effect of Choice of Intraoperative Opioid on Postoperative Pain
• Morphine as First Drug for Cancer Pain
• A Clinical Study To Characterize The Pharmacokinetics And The Effects Of Food On Oxycodone In Healthy Volunteers
• Pharmacokinetic Study of Hydrocodone/APAP in Chronic Pain Patients
• Milnacipran for Chronic Pain in Knee Osteoarthritis
• A Study of JNS020QD in Patients With Chronic Pain
• A Study of Naldemedine (S-297995) for the Treatment of Opioid-Induced Constipation in Adults With Non-Malignant Chronic Pain Receiving Opioid Therapy
• Pilot Study of Varenicline to Treat Opioid Dependence
• The Immune and Clinical Impacts of Vitamin D in Patients With Chronic Musculo-skeletal Pain
• Use of Fentanyl Patch in Partial Doses Than the Original
• Oral Ketamine for Control of Chronic Pain in Children
• Sedation in Endoscopic Retrograde Cholangiopancreatography (ERCP) With or Without Opioids
• Longterm Safety Study of BEMA Buprenorphine in Subjects With Chronic Pain
• Tapentadol in Chronic Malignant Tumour Related Pain
• Nasal Fentanyl for Patient Controlled Treatment of Pain in Cancer
• Study to Evaluate the Efficacy and Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) for Relief of Moderate to Severe Pain in Patients With Osteoarthritis or Low Back Pain Who Require Opioid Treatment for an Extended Period of Ti
• Study to Evaluate the Long-Term Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) in Patients Who Require Opioid Treatment for an Extended Period of Time
• Efficacy and Safety of Alisporivir Alone or Combined With RBV or PEG in Chronic Hepatitis C Genotype 2 and 3 Treatment-naïve Participants
• Effectiveness, Safety, and Tolerability Study of Oxymorphone Immediate Release (IR) Oral Liquid in Opioid Tolerant Pediatric Subjects
• The Effect of Pregabalin and Dexamethasone on Acute and Chronic Pain After Lumbar Spinal Surgery
• Open-Label Trial Comparing Oxycodone Medications
• Lidocaine 5% Medicated Plaster in Chronic Neuropathic Postoperative Pain
• A Phase 2 Study of Tapentadol Extended-Release (JNS024ER) ) in Japanese Participants With Chronic Pain Due to Diabetic Neuropathic Pain or Postherpetic Neuralgia
• An Efficacy and Safety Study for Tapentadol Extended Release (JNS024ER) in Chronic Pain Participants
• Study to Evaluate the Safety and Efficacy of Naldemedine (S-297995) for the Treatment of Opioid-Induced Bowel Dysfunction in Subjects With Chronic Pain
• A Study To Observe The Performance Of A Tablet Form Of PF-04531083 As Evidenced By The Concentration Of PF-04531083 In The Blood With Time Following Oral Administration To Healthy Volunteers.
• Paracetamol and Glutathion
• Long-Term Study of Hydrocodone Bitartrate Controlled-release Capsules in Subjects With Chronic Pain
• To Explore The Potential For PF-04531083 To Effect The Blood Concentrations Of Simvastatin And Its Main Acid Metabolite Following Co-Administration Of Both Medications
• Safety Study to Assess Opiate Withdrawal Signs and Symptoms in Opioid Dependent Patients
• Vitamin D Treatment to Patients Suffering From Chronic Pain and Vitamin D Hypovitaminosis
• A Confirmatory Study of Fentanyl in Participants With Osteoarthritis or Low Back Pain
• QTc and Perceived Sleep Follow up Among Chronic Pain Patients With Opiate Medication
• The Effect of Perioperative Pregabalin on the Incidence of Chronic Post-thoracotomy Pain Syndrome
• Lidocaine on Manifestations of Fibromyalgia
• Evaluation of Effectiveness and Tolerability of Tapentadol Hydrochloride in Subjects With Severe Chronic Low Back Pain Taking WHO Step III Analgesics But Showing a Lack of Tolerability
• Naloxone SR Capsules in Patients With Opioid Induced Constipation
• Evaluation of Effectiveness and Tolerability of Tapentadol Hydrochloride in Subjects With Severe Chronic Low Back Pain Taking Either WHO Step I or Step II Analgesics or no Regular Analgesics
• Evaluation of Effectiveness and Tolerability of Tapentadol Hydrochloride in Subjects With Severe Pain Due to Osteoarthritis Taking Either WHO Step I or Step II Analgesics or no Regular Analgesic
• Evaluation of Effectiveness and Tolerability of Tapentadol Hydrochloride in Subjects With Severe Pain Due to Osteoarthritis Taking WHO Step III Analgesics But Showing a Lack of Tolerability.
• A Safety and Efficacy Study of Sufentanil Transdermal System in Patients With Chronic Pain Due to Cancer
• Effect of Extended-release Oxymorphone Taking With or Without Food on Cognitive Functioning
• AZD2066 Cocktail Study
• Prospective Study About Clinical and Pharmacogenetic Safety of Opioid Use for Chronic Pain
• Oxymorphone Extended Release (ER) in Opioid-Naive Patients With Chronic Pain
• Oxymorphone Extended Release in Patients With Cancer or Neuropathic Pain
• Safety and Efficacy of AEG33773 Versus Placebo in Patients With Painful Diabetic Peripheral Neuropathy
• Buprenorphine and Methadone for Opioid Dependent Chronic Pain Patients
• A Multiple Dose Trial Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PF-04457845 in Healthy Volunteers
• Effect of Ketamine on Opioid-Induced Hyperalgesia
• Fentanyl Buccal Tablets Versus Immediate Release Oxycodone for Breakthrough Pain in Patients With Chronic Pain
• An Efficacy and Safety Study of Fentanyl in Participants With Chronic Pain
• Chronic Pain Management After Herniorraphy
• Open-Label Safety and Tolerability of Oxymorphone IR and ER in Opioid Tolerant Pediatric Subjects
• Efficacy and Safety of Tapentadol Extended Release Tablets in the Treatment of Moderate to Severe Pain in Subjects With Knee Osteoarthritis
• Hormone Function in Men Treated for Pain With Opioids or Placebo
• A Long-term Efficacy and Safety Study of Tramadol Hydrochloride Plus Acetaminophen (JNS013) in Japanese Participants With Chronic Pain
• An Efficacy and Safety Study of Acetaminophen Plus Tramadol Hydrochloride (JNS013) in Participants With Chronic Pain
• AZD1386 Japanese Multiple Ascending Dosing Study
• Lidocaine and Ketamine Versus Standard Care on Acute and Chronic Pain
• Matrifen® for Therapy of Severe Chronic Pain®
• Study to Investigate the Safety, Tolerability and Pharmacokinetics of AZD1386
• Pregabalin and Post-thoracotomy Pain
• A Study to Evaluate the Safety of D-TRANS Fentanyl With Naltrexone in Adult Patients With Chronic Pain and Who Are Opioid Tolerant
• Evaluation of Risk Minimization, Assessment and Outcomes in Patients With Chronic Pain Taking Avinza
• Clinical Trial of Integrated Treatment for Pain and Opioid Dependence
• A Double-blind Study of Controlled Release OROS Hydromorphone Compared to Placebo in Patients With Chronic Osteoarthritis (OA) Pain
• The Effect of Perioperative Ketamine on Acute and Chronic Pain After Major Back Surgery
• Sublingual Buprenorphine for Chronic Pain
• Study of D-Methadone in Patients With Chronic Pain
• Efficacy of Matrifen in Patients Older Than 18 Years With Severe, Chronic Pain
• Buprenorphine Transdermal System (BTDS) in Subjects w/Mod-sev Osteoarthritis (OA) Chronic Pain of Knee
• Botox for Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)
• An Open-label Extension Study With Flexible Dosing of Extended-release (ER) Tapentadol (CG5503) to Treat Patients With Moderate to Severe Chronic Pain
• A Study to Evaluate the Efficacy and Safety of CG5503 Prolonged Release (PR) in Subjects With Moderate to Severe Chronic Pain Due to Osteoarthritis of the Knee
• Open Label, Safety Study of EN3270 in Patients With Moderate to Severe Non-malignant, Chronic Pain
• Efficacy and Safety of Fentanyl Buccal Tablets Compared With Oxycodone for the Management of Break Through Pain
• A Study of Embeda (Kadian NT, ALO-01) in Subjects With Pain Due to Osteoarthritis of the Hip or Knee
• Trial of Analgesia With Lidocaine or Extended-release Oxycodone for Neuropathic Pain Treatment in Multiple Sclerosis
• Effects of Nefopam on Hyperalgesia After Cardiac Surgery
• Study of the Effectiveness and Tolerability of OROS Hydromorphone HCI SR(Slow-release) Tablets and Immediate-Release Hydromorphone Tablets in Patients With Chronic Pain
• A Repeated Dose Study of the Metabolism and Action Evaluation of OROS Hydromorphone HCI (Slow Release) Tablets in Patients With Chronic Pain
• Analgesic Efficacy of Testosterone Replacement in Hypogonadal Opioid-Treated Chronic Pain Patients: A Pilot Study.
• Open-Label Study to Evaluate the Effect of Treatment With Fentanyl Buccal Tablets on Pain Anxiety Symptoms When Used for the Management of Breakthrough Pain
• Evaluation of Stepped Care for Chronic Pain in Iraq/Afghanistan Veterans (ESCAPE)
• Efficacy of Opioids and Mexiletine for the Treatment of Postamputation Pain
• Effect of Delta-9-Tetrahydrocannabinol on the Prevention of Chronic Pain in Patients With Acute CRPS (ETIC-Study)
• A Study to Evaluate 90-Day Safety of Tapentadol(CG5503) Immediate Release (IR) or Oxycodone Immediate Release in Patients With Chronic Pain
• A Study to Evaluate Long-Term Safety of Multiple Doses of Tapentadol (CG5503) Prolonged-Release (PR) and Oxycodone Controlled-Release (CR) in Patients With Chronic Pain
• Opioid Rotation From Morphine to Methadone in Treatment of Non-malignant Pain
• A Study Comparing the Effectiveness and Safety of Extended Release Tramadol HCl at 100 mg, 200 mg and 300 mg Doses to Placebo for the Treatment of Moderate to Severe Pain Due to Osteoarthritis (OA)
• A Study Comparing the Effectiveness and Safety of Extended Release Tramadol Versus Placebo for the Treatment of Osteoarthritis (OA) of the Knee
• A Study Comparing the Effectiveness and Safety of Extended-release Tramadol Versus Placebo in the Treatment of Chronic Low Back Pain
• A One-year, Open-label Study to Assess the Safety and Effectiveness of Extended Release Tramadol HCl in the Treatment of Chronic, Non-malignant Pain.
• Study to Evaluate the Efficacy and Safety of OraVescent Fentanyl Citrate Treatment for the Management of Breakthrough Pain in Opioid-Tolerant Patients With Noncancer-Related Chronic Pain
• A Study Comparing the Effectiveness and Safety of Varying Dose Strengths (100, 200, 300 and 400 mg) of Extended-release Tramadol HCl With Placebo for the Treatment of Osteoarthritis(OA) of the Knee and/or Hip
• A Comparison of the Addiction Liability of Hydrocodone and Sustained Release Morphine
• Efficacy and Safety of SR46349B in Patients With Sleep Disorders in Fibromyalgia
• Safety and Effectiveness of Buprenorphine Transdermal System in Elderly Subjects With Chronic Pain: Pilot Study.
• Efficacy and Safety of FITpatch Compared to Standard Opioid Treatment in Cancer Pain (FT-015-IN)
• Evolution of Analgesic Tolerance With Opioids
• A Study to Assess the Safety, Dose Conversion, and Dose Individualization of Duragesic® (Fentanyl Transdermal Patch) in the Treatment of Children With Chronic Pain Requiring Narcotic Pain Relief Therapy
• A Study to Assess the Safety and Effectiveness of Durogesic (Fentanyl Transdermal Patch) in the Treatment of Children With Chronic Pain Requiring Long-term Narcotic Pain Relief Therapy
• A 15-day Study to Assess the Safety and Clinical Utility of Duragesic (Fentanyl Transdermal Patch) in the Treatment of Children With Continuous Pain Requiring Narcotic Pain Relief Therapy
• Efficacy and Safety of Oxymorphone Extended Release in Opioid-Experienced Patients With Chronic Non-Malignant Pain
• Efficacy and Safety of Oxmorphone Extended Release in Chronic Non-malignant Pain
• Study to Evaluate the Efficacy of Dronabinol (Marinol) as Add-On Therapy for Patients on Opioids for Chronic Pain
• Effect of Ketalar to Prevent Postoperative Chronic Pain After Mastectomy
• Fentanyl Transdermal Matrix Patch ZR-02-01 to Treat Chronic, Moderate to Severe Non-Malignant Pain
• Prialt (Ziconotide) In Severe Chronic Pain
• Chronic Pain in Spinal Cord Injury
• Chronic Pain After Amputation
• A Multicenter Phase II/III, Placebo-Controlled Study of SNX-111 Administered Intrathecally to Cancer and AIDS Patients With Chronic Pain