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Clinical Trials for Brain Neoplasms

• Defactinib and Avutometinib, With or Without Encorafenib, for the Treatment of Patients With Brain Metastases From Cutaneous Melanoma
• DATO-BASE: DATOpotamab-deruxtecan for Breast Cancer Brain metAstaSEs
• Bevacizumab and ICIs + hSRT in Symptomatic Melanoma Brain Metastases
• Pyrotinib Combined With Capecitabine and Bevacizumab for Patients With HER2 Positive Breast Cancer and Brain Metastases
• A Study of Cabozantinib and Nivolumab With Radiation Therapy for People With Renal Cell Carcinoma That Has Spread to the Brain
• Post-Operative Dosing of Dexamethasone in Patients With Brain Tumors After a Craniotomy, PODS Trial
• Study of Oral JYP0322 in Patients With Locally Advanced or Metastatic Cancer Targeting ROS1 Molecular Fusion.
• A Study of Avutometinib for People With Solid Tumor Cancers
• A Phase II Study of T-DXd Plus SRT in HER2-positive Breast Cancer Brain Metastases
• Trastuzumab Deruxtecan (T-DXd) for People With Brain Cancer
• Performance of Elucirem® in DSC-MRI Perfusion of Brain Gliomas
• 18F-Fluciclovine PET Amino Acid Evaluation of Brain Metastasis Treated With Stereotactic Radiosurgery
• Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis
• Delayed or Upfront Brain RAdiotherapy in Treatment naïve Lung Cancer Patients With Asymptomatic or Minimally Symptomatic Brain Metastases and ALK rEarrangements
• TY-9591 in the Patients With EGFR Mutations in Advanced NSCLC With Brain Metastases
• Clinical Trial of the ATM-Inhibitor WSD0628 in Combination With Radiation Therapy for Recurrent Brain Tumors
• Crizanlizumab Alone or in Combination With Nivolumab for Glioblastoma and Melanoma With Brain Metastases
• Levetiracetam Prophylaxis in Brain Tumor Resection Pilot
• A Study of ABM-1310 in Patients With BRAF V600-Mutant Relapsed and Drug Resistant Primary Malignant Brain Tumors
• Phase II Study of SPH4336 in Combination With Endocrine Therapy in Breast Cancer Patients With Brain Metastases.
• Phase II Study of Dato-DXd in Triple-negative Breast Cancer Patients With Newly Diagnosed or Progressing Brain Metastases
• HER3-DXd in Breast Cancer and NSCLC Brain Metastases and Solid Tumor Leptomeningeal Disease
• Effect of Preemptive Low Dose Norepinephrine Infusion on Intraoperative Hemodynamic Stability and Postoperative Outcomes in Patients Undergoing Brain Tumor Resection With a Craniotomy
• Study of Cadonilimab Combined With Bevacizumab and Chemotherapy for Advanced Nonsquamous Non-small Cell Lung Cancer Patients With Untreated Brain Metastases
• Study to Evaluate the Safety and Efficacy of Serplulimab Plus Bevacizumab and Chemotherapy in NSCLC Patients With Brain Metastases
• Armatinib Alone or in Combination With SRT for Brain Metastases EGFR-mutated Non-small Cell Lung Cancer
• Effect of Azeliragon Combined With Stereotactic Radiation Therapy in Patients With Brain Metastases
• A Phase 1 Study of BDTX-4933 in Patients With BRAF and Select RAS/MAPK Mutation Positive Cancers
• The Efficacy and Safety of Eutideron, Etoposide, and Bevacizumab in Patients With Brain Metastases From Breast Cancer.
• DETERMINE Trial Treatment Arm 3: Entrectinib in Adult, Teenage/Young Adults and Paediatric Patients With ROS1 Gene Fusion-positive Cancers.
• Study of SHR-A1811 in HER2-positive Advanced Breast Cancer With Brain Metastases
• Early or Delayed Intervention of Brain Radiotherapy Combined With Almonertinib in EGFR Mutated NSCLC With Brain Metastases
• Comparison of the Analgesic Effects of Scalp Nerve Block and Intravenous Ibuprofen Applications Under the Guidance of Nociception Level Index (NoL) in Patients Undergoing Elective Supratentorial Craniotomy
• Carboplatin, Pemetrexed, and Atezolizumab in Patients With Non-squamous Non-small Cell Lung Cancer (NSCLC) and Untreated Brain Metastases
• Dexmedetomidine Versus Magnesium Sulphate in Patients Undergoing Craniotomy for Deeply Settled Intracranial Tumours
• Pilot Study of Nivolumab w/Ipilimumab or Relatlimab in Surgically Resectable Melanoma Brain Metastases
• Phase II Study of Nivolumab in Combination With Relatlimab in Patients With Active Melanoma Brain Metastases
• Phase II Trial of the PARP Inhibitor Niraparib and PD-1 Inhibitor Dostarlimab in Patients With Advanced Cancers With Active Progressing Brain Metastases (STARLET)
• Reducing the Incidence of Symptomatic Brain Metastases With MRI Surveillance
• MeFAMP for Imaging System A Amino Acid Transport in Primary and Metastatic Brain Tumors
• A Phase II Study of Tucatinib and Ado-trastuzumab Emtansine (T-DM1) in Patients With HER2-positive Metastatic Solid Tumors and Metastases to Brain (TUCATEMEB)
• A Phase 1/2 Study of Oral IRAK-4 Inhibitor CA-4948 in Combination With Pembrolizumab Following Stereotactic Radiosurgery in Patients With Melanoma Brain Metastases
• Evaluation of Fluoxetine and Cytotoxic Lysosomal Stress in Glioma (FLIRT)
• Blood Brain Barrier (BBB) Disruption Using Exablate Focused Ultrasound With Doxorubicin for Treatment of Pediatric DIPG
• ARISTOCRAT: Blinded Trial of Temozolomide +/- Cannabinoids
• A Window of Opportunity Study of Patritumab Deruxtecan in Patients With Brain Metastases
• Blood Brain Barrier (BBB) Disruption Using Exablate Focused Ultrasound With Doxorubicin for Treatment of Pediatric DIPG
• Study of Zotiraciclib for Recurrent High-Grade Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations
• Immune Treatment of Brain Metastasis of Lung Cancer Combined With Large-segmentation Precision Radiotherapy
• Central Nervous System Efficacy of Capmatinib in NSCLC With Brain Metastases With cfDNA Positive MET Alterations
• Characterization of 18F-Fluciclovine PET Amino Acid Radiotracer in Resected Brain Metastasis
• 68Ga-RM26-RGD PET/CT Imaging in the GRPR and αvβ3 Positive Tumor Patients
• A Study to Learn About the Study Medicine Called PF-07799544 in People With Advanced Solid Tumors
• UTD1 Combined With Capecitabine in Metastatic HER2-negative Breast Cancer Patients With Brain Metastases
• Immunotherapy or Targeted Therapy With or Without Stereotactic Radiosurgery for Patients With Brain Metastases From Melanoma or Non-small Cell Lung Cancer
• Targeting Pediatric Brain Tumors With Sodium Glucose Cotransporter 2 Inhibitors (SGLT2i)
• Lazertinib/Pemetrexed/Carboplatin After Osimertinib Failure in NSCLC With Brain Metastases
• Efficacy and Safety of Furmonertinib in Patients With EGFR Mutations in Advanced NSCLC With Brain Metastases: A Single-center, Open-label, Phase II Trial（iFORCE）
• Efficacy and Safety Evaluation of Percutaneous Ommaya Capsule Injection of Autologous Bi-dimensional Specific T Cells in the Treatment of Glioma and in Combination With Pemetrexed in the Treatment of Brain/Meningeal Metastases
• Fluorine-18-AlphaVBeta6-Binding Peptide Positron Emission Tomography in Metastatic Non-Small Cell Lung Cancer
• MW151 and HA-WBRT in Patients With Brain Metastases
• Study of Abemaciclib and Elacestrant in Patients With Brain Metastasis Due to HR+/Her2- Breast Cancer
• Utidelone Plus Bevacizumab for Advanced Breast Cancer With Brain Metastases
• Lazertinib in Patients With NSCLC With Asymptomatic or Mild Symptomatic Brain Metastases After Failure of EGFR TKI.
• Secondary BRain Metastases Prevention After Isolated Intracranial Progression on Trastuzumab/Pertuzumab or T-DM1 in Patients With aDvanced Human Epidermal Growth Factor Receptor 2+ brEast Cancer With the Addition of Tucatinib
• Blood-brain Barrier (BBB) Disruption Using Exablate Focused Ultrasound With Standard of Care Treatment of NSCLC Brain Mets
• Study Assessing QBS72S For Treating Brain Metastases of Triple Negative Breast Cancer
• Repeated Superselective Intraarterial Cerebral Infusion (SIACI) of Bevacizumab With Temozolomide and Radiation Compared to Temozolomide and Radiation Alone in Newly Diagnosed GBM
• Combination Liposomal Irinotecan and Pembrolizumab For Triple-Negative Breast Cancer (TNBC) With Brain Metastases (BM)
• Observation or Upfront Cranial RT in Oncogene Mutated NSCLC With Asymptomatic BM: A Phase III RCT
• Tislelizumab Plus Chemotherapy as First-Line Treatment for Advanced Squamous NSCLC With Brain Metastases
• A Phase I/II Study of AMG 510 in Combination With MVASI in Patients With Advanced, Unresectable or Metastatic KRAS G12C Mutant NSCLC With Asymptomatic Brain Metastasis
• Magrolimab in Children and Adults With Recurrent or Progressive Malignant Brain Tumors
• High Dose Chemotherapy With Amifostine and Autologous Stem Cell Transplantation for High Risk Relapsed Pediatric Solid Tumors and Brain Tumors
• Study of TY-9591 in Patients With a Lung Cancer With Brain or Leptomeningeal Metastases With EGFR Mutation
• Influences of Propofol and Sevoflurane Anesthesia in Brain Tumor
• Low Dose Versus Standard Dose Dexamethasone for Reduction of Swelling in Patients With Primary or Metastatic Brain Tumors
• REMASTer: REcurrent Brain Metastases After SRS Trial
• A Phase 1a/1b Study to Determine the Recommended Phase 2 Dose, of Tepotinib in Participants With MET Alterations and Brain Tumors
• Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain Cancer
• Osimertinib Combined With Bevacizumab in Patients With Brain Metastasis Epidermal Growth Factor Receptor (EGFR) Mutation Positive Metastatic Non-Small Cell Lung Cancer
• The Efficacy of HLX208 (BRAF V600E Inhibitor) for Refractory Primary Brain Tumors With BRAF Mutation After First-line Treatment
• Phase II Study of Pembrolizumab in Combination With Lenvatinib in Patients With TNBC, NSCLC, and Other Tumor Types and Brain Metastases
• Study of Laser Interstitial Thermal Therapy (LITT) Treatment Response Assessment With Fluciclovine PET MR
• Does Perioperative Intravenous Magnesium Affect Postoperative Quality of Recovery in Craniotomy Surgery Patients?
• A Phase II Study of Nivolumab With Ipilimumab and Cabozantinib in Patients With Untreated Renal Cell Carcinoma Brain Metastases
• Optimizing Neurocognition With Whole Brain Radiation Therapy (WBRT) Using Upfront Pulsed Reduced Dose-Rate (PRDR) Technique
• Tolerability and Activity of Brivaracetam (BRV) in Patients With Diffuse Gliomas
• Toripalimab Combined With Anlotinib and SBRT in Patients With Untreated Brain Metastases of Driven Gene-negative NSCLC
• ARX788 in HER2-positive Breast Cancer Patients With Brain Metastases
• NTS-WBRT VS HA-WBRT in Brain Metastases
• Study of Nivolumab and Ipilimumab Plus Chemotherapy as a Treatment for Patients With Stage IV Lung Cancer With Brain Metastases
• the Efficacy and Safety of Anlotinib Combined With Almonertinib in the First-line Treatment of Patients With Brain Metastases From EGFR Mutation-positive Non-small Cell Lung Cancer
• Pembrolizumab With Standard Cytotoxic Chemotherapy in Treatment Naive Non-small Cell Lung Cancer Patients With Asymptomatic Brain Metastases
• Trial of Neratinib Plus Capecitabine in Subjects With HER2-Negative Metastatic Breast Cancer With Brain Metastases and Abnormally Active HER2 Signaling
• Pembro+Chemo in Brain Mets
• Anesthesia Induced Brain Cancer Survival (ABC Survival): A Feasibility Study
• Pembrolizumab and Lenvatinib in Patients With Brain Metastases From Melanoma or Renal Cell Carcinoma
• The Application of Glucose CEST MR Imaging in Brain Tumor
• A Study to See if Memantine Protects the Brain During Radiation Therapy Treatment for a Brain Tumor
• Stereotactic Radiation & Abemaciclib in the Management of HR+/HER2- Breast Cancer Brain Metastases
• Almonertinib Combined With Cerebral Radiation Treat Brain Metastases From EGFR Positive NSCLC
• Study of PBI-200 in Subjects With NTRK-Fusion-Positive Solid Tumors
• Stereotactic Brain-directed Radiation With or Without Aguix Gadolinium-Based Nanoparticles in Brain Metastases
• A Study of Panobinostat in Pediatric Patients With Solid Tumors Including MRT/ATRT
• Radiosurgery Before Surgery for the Treatment of Brain Metastases
• Durvalumab (MEDI4736) and Radiosurgery (fSRT vs. PULSAR) for the Treatment of Non-Small Cell Lung Cancer Brain Metastases
• Almonertinib Versus Osimertinib in the Patients With EGFR Mutations in Advanced NSCLC With Brain Metastases
• Evaluation of Neratinib for Treatment and Prevention of Subsequent CNS Event(s) in Patients With Brain Metastasis of Advanced HER2 Positive Breast Cancer
• Keynatinib in Treated Patients With NSCLC and Brain Metastases
• Almonertinib as First-line Treatment in Patients With EGFR Mutations Positive in Advanced NSCLC With Brain Metastases
• Neurocognitive Outcome of Bilateral or Unilateral Hippocampal Avoidance WBRT With Memantine for Brain Metastases
• Multicenter Open Label Phase Ib/II Trial of Abemaciclib and Elacestrant in Patients With Brain Metastasis Due to HR+/Her2- Breast Cancer
• A Dose Exploration Study of Almonertinib for EGFRm NSCLC Patients With Brain/Leptomeningeal Metastasis (ARTISTRY)
• MEP and Neuromuscular Blocker
• Camrelizumab Combined With SRT/WBRT and Chemotherapy in Patients With Brain Metastases of Driven Gene-negative NSCLC
• A Single Arm Study of Brain Metastasis in Patients With HER2-positive Breast Cancer
• TKIs vs. Pertuzumab in HER2+ Breast Cancer Patients With Active Brain Metastases (HER2BRAIN)
• SGM-101 in Colorectal Brain Metastases.
• 18F-FMAU PET/CT and MRI for the Detection of Brain Tumors in Patients With Brain Cancer or Brain Metastases
• Phase II Study of T-DX in HER2-positive Breast Cancer Brain Metastases
• A Study of T-DXd in Participants With or Without Brain Metastasis Who Have Previously Treated Advanced or Metastatic HER2 Positive Breast Cancer
• Clinical Safety Study on 5-Aminolevulinic Acid (5-ALA) in Children and Adolescents With Supratentorial Brain Tumors
• ONC206 for Treatment of Newly Diagnosed, or Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant Brain Tumors (PNOC 023)
• Study of [68Ga]-FF58 in Patients With Selected Solid Tumors Expected to Overexpress αvβ3 and αvβ5 Integrins.
• Study of Stereotactic Radiosurgery With Olaparib Followed by Durvalumab and Physician's Choice Systemic Therapy in Subjects With Breast Cancer Brain Metastases
• Assess Use of 18F-Fluciclovine for Patients With Large Brain Metastases Treated With Staged Stereotactic Radiosurgery
• Central Nervous System(CNS) Efficacy of Dacomitinib
• Study Comparing Investigational Drug HBI-8000 Combined With Nivolumab vs. Nivolumab in Patients With Advanced Melanoma
• Evaluation of Maximum Tolerated Dose, Safety and Efficiency of MSC11FCD Therapy to Recurrent Glioblastoma Patients
• SRS Timing With Immune Checkpoint Inhibition in Patients With Untreated Brain Metastases From Non-small Cell Lung Cancer
• A Home-Based Approach Study to Evaluate the Efficacy and Safety of Alectinib in Locally-Advanced or Metastatic ALK-Positive Solid Tumors
• A Phase II Trial of Upfront Radiotherapy Plus Almonertinib for Epidermal Growth Factor Receptor(EGFR)-Mutant Non-small-cell Lung Cancer(NSCLC) Patients With Brain Metastases
• Pyrotinib, Trastuzumab And Abraxane in HER2-positive MBC With Brain Metastasis
• Brigatinib Before Brain Irradiation Trial (B3i Trial)
• Chemotherapy and Atezolizumab for Patients With Extensive Stage Small Cell Lung Cancer (SCLC) With Untreated, Asymptomatic Brain Metastases
• Testing the Addition of Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in People With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radio
• Stereotactic Radiosurgery With Abemaciclib, Ribociclib, or Palbociclib in Treating Patients With Hormone Receptor Positive Breast Cancer With Brain Metastases
• Survivorship Study of Cancer Patients Who Received Cranial Radiation Therapy
• A FIH Study of PF-07284890 in Participants With BRAF V600 Mutant Solid Tumors With and Without Brain Involvement
• RRx-001 Given With Irinotecan and Temozolomide for Pediatric Patients With Recurrent or Progressive Malignant Solid and Central Nervous System Tumors
• Chemotherapy and Donor Stem Transplant for the Treatment of Patients With High Grade Brain Cancer
• TOPAZ: Tucatinib in COmbination With Pembrolizumab And TrastuZumab in Patients With HER2-Positive Breast Cancer Brain Metastases
• A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases
• CAR T Cells After Lymphodepletion for the Treatment of IL13Rα2 Positive Recurrent or Refractory Brain Tumors in Children
• Tislelizumab Combined With Pemetrexed/ Carboplatin in Patients With Brain Metastases of Non-squamous NSCLC
• Accelerated Checkpoint Therapy for Any Steroid Dependent Patient With Brain Metastases
• Prospective Exploratory Study of FAPi PET/CT With Histopathology Validation in Patients With Various Cancers
• Neoadjuvant Immunotherapy in Brain Metastases
• Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072S
• DS-8201a for trEatment of aBc, BRain Mets, And Her2[+] Disease
• X-396 (Ensartinib) Capsules in ALK-Positive NSCLC Patients With Brain Metastases
• Cytoprotective Effect and Clinical Outcome of Perioperative Proesterone in Brain Tumors
• Study to Establish Image Interpretation Criteria for 18F Fluciclovine PET in Detecting Recurrent Brain Metastases (PURSUE)
• Study to Establish the Diagnostic Performance of 18F Fluciclovine PET in Detecting Recurrent Brain Metastases
• GM1 Prophylaxis for WBRT Related Cognitive Dysfunction
• Dendritic Cell Vaccines Against Her2/Her3, Cytokine Modulation Regimen, and Pembrolizumab for the Treatment of Brain Metastasis From Triple Negative Breast Cancer or HER2+ Breast Cancer
• Phase I Study of Marizomib + Panobinostat for Children With DIPG
• An Open Label, Multicenter, Phase II Study of Dacomitinib for EGFR Mutated Non-Small Cell Lung Cancer (NSCLC) With Brain Metastases
• AflacST1901: Peds WP1066
• Palbociclib, Trastuzumab, Lapatinib and Fulvestrant Treatment in Patients With Brain Metastasis From ER Positive, HER-2 Positive Breast Cancer: A Multi-center, Prospective Study in China
• Analysis of Gut Microbiota in Patients With Brain Metastasis of Non-small Cell Lung Cancer Treated by Pembrolizumab Combined With Chemotherapy
• Comparison of Hypertonic Saline and Mannitol on Brain Relaxation During Supratentorial Tumors Resection
• Integrated Pulmonary Index and Opioid Based Patient Controlled Analgesia
• A Multi-cohort Phase II Study of HER2-positive and Triple-negative Breast Cancer Brain Metastases.
• Camrelizumab Combined With Local Treatment in NSCLC Patients With BM
• Molecular Imaging of Brain Tumors Using Labeled Technetium-99m 1-Thio-D-Glucose.
• Effect of Dexmedetomidine on Brain Homeostasis and Neurocognitive Outcome
• Study of Osimertinib in Patients With a Lung Cancer With Brain or Leptomeningeal Metastases With EGFR Mutation
• Sintilimab Combined With Bevacizumab for Brain Metastases From Non-small Cell Lung Cancer
• Camrelizumab With AC in Patients With Brain Metastases of Driven Gene-negative,NSCLC
• The Role of Brain Radiotherapy in Patients With Asymptomatic Brain Metastasis in the Era of Targeted Therapy for NSCLC
• GDC-0084 With Radiation Therapy for People With PIK3CA-Mutated Solid Tumor Brain Metastases or Leptomeningeal Metastases
• A Study of HER2+ Breast Cancer Patients With Active Brain Metastases Treated With Afatinib & T-DM1 vs. T-DM1 Alone
• Stereotactic Radiosurgery Combination With Anlotinib for Limited Brain Metastases With Perilesional Edema in NSCLC
• Effects of Pre-emptive Scalp Infiltration With Ketorolac and Ropivacaine for Post-craniotomy Pain
• Novel MRI Techniques for the Characterization and Treatment Assessment of High Grade Brain Lesions
• NovoTTF-200A + Pembrolizumab In Melanoma Brain Metastasis
• C7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B)
• Evaluating AGuIX® Nanoparticles in Combination With Stereotactic Radiation for Brain Metastases
• Pilot Study of Abemaciclib With Bevacizumab in Recurrent Glioblastoma Patients With Loss of CDKN2A/B or Gain or Amplification of CDK4/6
• Binimetinib Encorafenib Pembrolizumab +/- Stereotactic Radiosurgery in BRAFV600 Melanoma With Brain Metastasis
• A Study to Determine the Efficiency For Brain Metastasis NSCLC Patients Treated With Icotinib Alone or Combined With Radiation Therapy
• Gemcitabine in Newly-Diagnosed Diffuse Midline Glioma
• Pediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPG
• Fluoroethyltyrosine in Detecting Tumors in Participants With Recurrent Intracranial Tumors
• Evaluation of LY2606368 Therapy in Combination With Cyclophosphamide or Gemcitabine for Children and Adolescents With Refractory or Recurrent Group 3/Group 4 or SHH Medulloblastoma Brain Tumors
• Safety and Efficacy of Sonocloud Device Combined With Nivolumab in Brain Metastases From Patients With Melanoma
• Sonidegib and Pembrolizumab in Treating Patients With Advanced Solid Tumors
• Efficacy of metfOrmin in PrevenTIng Glucocorticoid-induced Diabetes in Patients With Brain Metastases
• Anti-PD-1 +/- RT for MSI-H Solid Tumors
• Neuro/Sacituzumab Govitecan/Breast Brain Metastasis/Glioblastoma/Ph 0
• Genetic Testing in Guiding Treatment for Patients With Brain Metastases
• Study of Binimetinib With Encorafenib in Adults With Recurrent BRAF V600-Mutated HGG
• Evaluation of Cabozantinib in Metastatic Renal Cell Carcinoma (mRCC) With Brain Metastases
• Imaging Perfusion Restrictions From Extracellular Solid Stress - An Open-label Losartan Study
• Study of the Bromodomain (BRD) and Extra-Terminal Domain (BET) Inhibitor BMS-986158 in Pediatric Cancer
• Adoptive Transfer of Tumor Infiltrating Lymphocytes for Advanced Solid Cancers
• A Study of Pyrotinib Plus Vinorelbine in Patients With Brain Metastases From HER2-positive Metastatic Breast Cancer
• 18F-Fluciclovine PET to Distinguish Tumor Progression From Radiation Necrosis
• 18F-Fluciclovine PET and Multiparametric MR Imaging
• Efficacy of Nivolumab for Recurrent IDH Mutated High-Grade Gliomas
• An Open-Label, Randomized, Multicenter Trial of Encorafenib + Binimetinib Evaluating a Standard-dose and a High-dose Regimen in Patients With BRAFV600-mutant Melanoma Brain Metastasis
• Encorafenib and Binimetinib Before Local Treatment in Patients With BRAF Mutant Melanoma Metastatic to the Brain
• Brigatinib in Treating Patients With ALK and ROS1 Gene Alterations and Locally Advanced or Metastatic Solid Cancers
• Imaging Oxidative Metabolism and Neurotransmitter Synthesis in the Human Brain
• Hyperpolarized Carbon C 13 Pyruvate in Diagnosing Glioma in Patients With Brain Tumors
• Radiotherapy of Multiple Brain Metastases Using AGuIX®
• Stereotactic Radiation and Nivolumab in the Management of Metastatic Breast Cancer Brain Metastases
• A Study of a New Drug Combination, Copanlisib and Fulvestrant, in Advanced Breast Cancer
• Ketoconazole Before Surgery in Treating Patients With Recurrent Glioma or Breast Cancer Brain Metastases
• HFSRT With Concurrent TMZ for Large BMs
• Study of Osimertinib + SRS vs Osimertinib Alone for Brain Metastases in EGFR Positive Patients With NSCLC
• GDC-0084 in Combination With Trastuzumab for Patients With HER2-Positive Breast Cancer Brain Metastases
• Azoles Targeting Recurrent High Grade Gliomas
• Icotinib Combined With Radiation Therapy For NSCLC Patients With Brain Metastases and EGFR Mutation
• X-396(Ensartinib) Capsules in ALK-Positive NSCLC Patients With Brain Metastases
• Tumor Treating Fields With Chemoradiation in Newly Diagnosed GBM
• Precise DCE-MRI in Diagnosing Participants With Recurrent High Grade Glioma or Melanoma Brain Metastases
• A Study of Pyrotinib Plus Capecitabine in Patients With Brain Metastases From HER2-positive Metastatic Breast Cancer
• DM-CHOC-PEN for Brain Tumors in AYA Subjects
• Phase 1 Study of the Dual MDM2/MDMX Inhibitor ALRN-6924 in Pediatric Cancer
• First Line Treatment in EGFR Mutation Positive Advanced NSCLC Patients With Central Nervous System (CNS) Metastases
• A Safety and Tolerability Study of INCAGN02390 in Select Advanced Malignancies
• Feasibility of FMISO in Brain Tumors
• Eribulin in Brain Metastases From HER2-negative Breast Cancer
• The Effect of Vitamin D3 on Postoperative Pain in Patients Undergoing Craniotomy
• Endostar Combine With Radiotherapy in Brain Metastasis of NSCLC
• ANG1005 in Leptomeningeal Disease From Breast Cancer
• A Trial for Treatment of Cancer Patients With Multiple Brain Metastases Undergoing Whole-Brain Radiotherapy
• Therapeutic Targeting of Sex Differences in Pediatric Brain Tumor Glycolysis
• Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5-15 Brain Metastases
• [18F]DASA-23 and PET Scan in Evaluating Pyruvate Kinase M2 Expression in Patients With Intracranial Tumors or Recurrent Glioblastoma and Healthy Volunteers
• Osimertinib With Stereotactic Radiosurgery (SRS) in Brain Metastases From EGFR Positive NSCLC
• Atezolizumab in Combination With Carboplatin Plus Pemetrexed in Chemotherapy-naïve Patients With Asymptomatic Brain Metastasis
• Regorafenib and Methotrexate in Treating Participants With Recurrent or Metastatic KRAS Mutated Non-Small Cell Lung Cancer
• Panitumumab-IRDye800 in Diagnosing Participants With Malignant Glioma Undergoing Surgery
• A Randomised Phase II Trial of Osimertinib With or Without SRS for EGFR Mutated NSCLC With Brain Metastases
• Atezolizumab + Stereotactic Radiation in Triple-negative Breast Cancer and Brain Metastasis
• Dose Escalation Study of CLR 131 in Children, Adolescents, and Young Adults With Relapsed or Refractory Malignant Tumors Including But Not Limited to Neuroblastoma, Rhabdomyosarcoma, Ewings Sarcoma, and Osteosarcoma
• A First in Human Study Using 89Zr-cRGDY Ultrasmall Silica Particle Tracers for Malignant Brain Tumors
• Open-label PET Study With [11C]Osimertinib in Patients With EGFRm NSCLC and Brain Metastases
• FET-PET/MRI for Surgical Assessment of Pediatric Brain Tumors
• Pembrolizumab And Stereotactic Radiosurgery (Srs) Of Selected Brain Metastases In Breast Cancer Patients
• Seizure Prophylaxis Study
• SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors
• Vemurafenib Plus Cobimetinib After Radiosurgery in Patients With BRAF-mutant Melanoma Brain Metastases
• A Longitudinal Assessment of Tumor Evolution in Patients With Brain Cancer
• A Study to Assess the Safety and Tolerability of AZD1390 Given With Radiation Therapy in Patients With Brain Cancer
• S1501 Carvedilol in Preventing Cardiac Toxicity in Patients With Metastatic HER-2-Positive Breast Cancer
• A Pilot Study of Eribulin in Breast Cancer (BC) Patients With Brain Metastases Previously Treated With Anthracyclines and Taxanes
• Ribociclib and Everolimus in Treating Children With Recurrent or Refractory Malignant Brain Tumors
• Ferumoxytol MRI in Assessing Response to Pembrolizumab in Patients With Glioblastoma
• E6201 Plus Dabrafenib for the Treatment of Metastatic Melanoma Central Nervous System Metastases (CNS)
• Evaluation of 68-GaNOTA-Anti-HER2 VHH1 Uptake in Brain Metastasis of Breast Carcinoma Patients
• A Study of Ad-RTS-hIL-12 + Veledimex in Pediatric Subjects With Brain Tumors Including DIPG
• Evaluation of the Efficacy and Safety of Nal-IRI for Progressing Brain Metastases in Breast Cancer Patients
• Pembrolizumab and Magnetic Resonance Imaging With Ferumoxytol in Treating Patients With Non-small Cell Lung Cancer and Brain Metastases
• Role of Hyperpolarized 13C-Pyruvate MR Spectroscopy in Patients With Intracranial Metastasis Treated With (SRS)
• Magnesium Sulphate for Attenuation of Hemodynamic Pressor Response After Myfield's Clamp Application
• PEP-CMV in Recurrent MEdulloblastoma/Malignant Glioma
• Radiation Therapy With Combination Immunotherapy for Relapsed/Refractory Metastatic Melanoma
• Safety and Efficacy of the ONCOlytic VIRus Armed for Local Chemotherapy, TG6002/5-FC, in Recurrent Glioblastoma Patients
• [18F]Fluciclovine and [18F]FLT PET/CT Assessment of Primary High-Grade Brain Tumors
• Two-Part Study to Evaluate the Safety and Efficacy of Image Guided Surgery Using Indocyanine Green for Intramolecular Imaging of Nervous System Tumors Compared to Standard of Care, (TumorGlow)
• A Study of Pomalidomide Monotherapy for Children and Young Adults With Recurrent or Progressive Primary Brain Tumors
• Therapeutic Benefit of Preoperative Supplemental Vitamin D in Patients Undergoing Brain Tumor Surgery
• Ferumoxytol in Magnetic Resonance Imaging of Pediatric Patients With Brain Tumors
• Abemaciclib (LY2835219) in Patients With Recurrent Primary Brain Tumors
• 18F-FET PET in Childhood Brain Tumours
• A Study to Test the Safety of the Investigational Drug Selitrectinib in Children and Adults That May Treat Cancer
• Oral Capecitabine and Temozolomide (CAPTEM) for Newly Diagnosed GBM
• Kadcyla In pAtients With bRAin Metastasis
• Memantine for Prevention of Cognitive Late Effects in Pediatric Patients Receiving Cranial Radiation Therapy for Localized Brain Tumors
• T-DM1 Alone Versus T-DM1 and Metronomic Temozolomide in Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases Following Stereotactic Radiosurgery
• In Vivo Characterization of Macrophages in Pediatric Patients With Malignant Brain Tumors Using Ferumoxytol-enhanced MRI
• Scalp Block: Hemodynamic Stability and Patient Comfort In Craniotomy Patients
• Bevacizumab and Atezolizumab With or Without Cobimetinib in Treating Patients With Untreated Melanoma Brain Metastases
• A Study of the Treatment of Recurrent Malignant Glioma With rQNestin34.5v.2
• VAL-083 Phase 3 Study in Temozolomide-Avastin (Bevacizumab) Recurrent GBM
• Study of Letrozole in Recurrent Gliomas
• Neoepitope-based Personalized Vaccine Approach in Pediatric Patients With Recurrent Brain Tumors
• Metabolic Characteristics of Brain Tumors Using Hyperpolarized Carbon-13 Magnetic Resonance Spectroscopic Imaging (MRSI)
• Safety Study of VAL-083 and Radiotherapy in Patients With Newly Diagnosed GBM Having Unmethylated MGMT Expression
• A Phase II/III Study of High-dose, Intermittent Sunitinib in Patients With Recurrent Glioblastoma Multiforme
• Ropidoxuridine and Whole Brain Radiation Therapy in Treating Patients With Brain Metastases
• Pilot Study of Nivolumab in Pediatric Patients With Hypermutant Cancers
• Combining Radiosurgery and Nivolumab in the Treatment of Brain Metastases
• Concurrent Dabrafenib + Trametinib With Sterotactic Radiation in BRAF Mutation-Positive Malignant Melanoma and Brain Metastases
• Open Label, Prospective Study to Investigate Efficacy and Safety of AZD9291 in BM From NSCLC Patients With EGFR T790M
• Osimertinib With or Without Bevacizumab in Treating Patients With EGFR Positive Non-small Cell Lung Cancer and Brain Metastases
• Gadobutrol Versus Gadopentetate Dimeglumine or Gadobenate Dimeglumine Before DCE-MRI in Diagnosing Patients With Multiple Sclerosis, Grade II-IV Glioma, or Brain Metastases
• Single Dose Tramadol Effect on Extubation Response and Quality of Emergence Post-supratentorial Intracranial Surgery
• Pilot Study of Safety and Toxicity of Acquiring Hyperpolarized Carbon-13 Imaging in Children With Brain Tumors
• Cerebral Oxygenation and Metabolism After Reversal Of Rocuronium: Comparison Between Sugammadex Versus Neostigmine
• Zotiraciclib (TG02) Plus Dose-Dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of Zotiraciclib (TG02) Plus Temozolomide Versus Temozolomide Alone in Adults With Recurrent Anaplastic Astrocytoma and Glioblastoma
• A Study of Etirinotecan Pegol (NKTR-102) Versus Treatment of Physician's Choice (TPC) in Patients With Metastatic Breast Cancer Who Have Stable Brain Metastases and Have Been Previously Treated With an Anthracycline, a Taxane, and Capecitabine
• Trial of CUDC-907 in Children and Young Adults With Relapsed or Refractory Solid Tumors, CNS Tumors, or Lymphoma
• Methotrexate and Etoposide Infusions Into the Fourth Ventricle in Children With Recurrent Posterior Fossa Brain Tumors
• Temozolomide Plus Bevacizumab in Supratentorial Glioblastoma in 70 Years and Older Patients With an Impaired Functional Status
• Palbociclib In Progressive Brain Metastases
• Pembrolizumab In Central Nervous System Metastases
• Pilot Study of Cabozantinib for Recurrent or Progressive Central Nervous System Tumors in Children
• Dual Time Point FDG PET-MR Imaging Optimization for the Evaluation of Glioblastoma
• Hypofractionated Brain Radiation In EGFR Mutated Adenocarcinoma Cranial Disease (Hybrid)
• Hypovitaminosis D in Neurocritical Patients
• Super-selective Intra-arterial Repeated Infusion of Cetuximab for the Treatment of Newly Diagnosed Glioblastoma
• Cetuximab-IRDye 800CW in Detecting Tumors in Patients With Malignant Glioma Undergoing Surgery
• A Pilot Surgical Trial To Evaluate Early Immunologic Pharmacodynamic Parameters For The PD-1 Checkpoint Inhibitor, Pembrolizumab (MK-3475), In Patients With Surgically Accessible Recurrent/Progressive Glioblastoma
• A Clinical Trial on Whole-brain Radiotherapy With Temozolomide Concurrent Chemotherapy or Avoidance of Hippocampus for Patients of Brain Metastases
• Radiosensitization of Multiple Brain Metastases Using AGuIX Gadolinium Based Nanoparticles
• Dexmedetomidine and Intelligence Development in Pediatric Patients Undergoing Craniotomy
• Super Selective Intra-arterial Repeated Infusion of Cetuximab (Erbitux) With Reirradiation for Treatment of Relapsed/Refractory GBM, AA, and AOA
• CEST- Glucose Enhanced MRI for Metastatic Brain Tumours
• Palbociclib in Treating Patients With Metastatic HER-2 Positive Breast Cancer With Brain Metastasis
• Anti-ESO (Cancer/Test Antigen) mTCR-transduced Autologous Peripheral Blood Lymphocytes and Combination Chemotherapy in Treating Patients With Metastatic Cancer That Expresses NY-ESO-1
• Feasibility Trial of the Modified Atkins Diet and Bevacizumab for Recurrent Glioblastoma
• Cambridge Brain Mets Trial 1
• Expanded Access to ANG1005 for Individual Patients
• Demeclocycline Fluorescence for Intraoperative Delineation Brain Tumors
• Intracranial Activity of AZD9291 (TAGRISSO) in Advanced EGFRm NSCLC Patients With Asymptomatic Brain Metastases
• 64-Cu Labeled Brain PET/MRI for MM-302 in Advanced HER2+ Cancers With Brain Mets
• High Dose Icotinib With Sequential SRS For NSCLC Patients Harboring EGFR Mutation With Brain Metastases
• Study of VAL-083 in Patients With MGMT Unmethylated, Bevacizumab-naive Glioblastoma in the Adjuvant or Recurrent Setting
• EGFR-TKI Concurrent With/Without WBRT in Brain Metastasis From NSCLC
• Vasopressor Effects in Anesthetized Patients
• Brain Relaxation With Mannitol and Furosemide
• Sugammadex Given for the Reversal of Rocuronium Induced Neuromuscular Blockade Under Sevoflurane Anesthesia in Infants
• Fluid Therapy During Brain Tumor Resection in Children
• Trial of Nivolumab With Radiation or Nivolumab and Ipilimumab With Radiation for the Treatment of Intracranial Metastases From Non-Small Cell Lung Cancer
• Diagnostic Performance of Fluorescein as an Intraoperative Brain Tumor Biomarker
• Phase II Study of Intraventricular Methotrexate in Children With Recurrent or Progressive Malignant Brain Tumors
• Pembrolizumab Plus Bevacizumab for Treatment of Brain Metastases in Metastatic Melanoma or Non-small Cell Lung Cancer
• Fractionated Stereotactic Radiosurgery With Concurrent Bevacizumab for Brain Metastases: A Phase I Dose-escalation Trial
• MEDI4736 (Durvalumab) in Patients With Brain Metastasis From Epithelial-derived Tumors
• An Investigational Immuno-therapy Study of Temozolomide Plus Radiation Therapy With Nivolumab or Placebo, for Newly Diagnosed Patients With Glioblastoma (GBM, a Malignant Brain Cancer)
• Ipilimumab Combined With a Stereotactic Radiosurgery in Melanoma Patients With Brain Metastases
• Autologous CMV-Specific Cytotoxic T Cells and Temozolomide in Treating Patients With Glioblastoma
• Bevacizumab and Erlotinib in Lung Cancer With Brain Metastases, a Phase II Trial
• Stereotactic Radiotherapy Plus Temozolomide for Refractory Brain Metastases
• Abemaciclib in Children With DIPG or Recurrent/Refractory Solid Tumors
• Phase I Study of Mebendazole Therapy for Recurrent/Progressive Pediatric Brain Tumors
• Study of Genistein in Pediatric Oncology Patients (UVA-Gen001)
• Nivo/Ipi Combination Therapy in Symptomatic Brain Metastases
• An Investigational Immuno-therapy Study of Nivolumab Compared to Temozolomide, Each Given With Radiation Therapy, for Newly-diagnosed Patients With Glioblastoma (GBM, a Malignant Brain Cancer)
• Study of Tesevatinib in Subjects With Non-Small Cell Lung Cancer, EGFR Activating Mutation, Prior Treatment With a Tyrosine Kinase Inhibitor, and Brain Metastases or Leptomeningeal Metastases
• Temozolomide in Preventing Brain Metastases in Small Cell Lung Cancer
• Preoperative Ceritinib (LDK378) in Glioblastoma Multiforme and CNS Metastasis
• Intrathecal Pertuzumab and Trastuzumab in Patients With New Untreated Asymptomatic or Low Symptomatic Brain Metastasis in HER2 Positive Breast Cancer
• Cisplatin With or Without Veliparib in Treating Patients With Recurrent or Metastatic Triple-Negative and/or BRCA Mutation-Associated Breast Cancer With or Without Brain Metastases
• Testing the Safety of M6620 (VX-970) When Given With Standard Whole Brain Radiation Therapy for the Treatment of Brain Metastases From Non-small Cell Lung Cancer, Small Cell Lung Cancer, or Neuroendocrine Tumors
• Tumor Hypoxia With HX4 PET in Several Diseases
• Treatment of Brain Metastases From Breast Cancer With Eribulin Mesylate
• A Study to Test the Effect of the Drug Larotrectinib in Adults and Children With NTRK-fusion Positive Solid Tumors
• Effect of Propofol-Dexmedetomidine on Cerebral Oxygenation and Metabolism During Brain Tumor Resection
• Basket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK 1/2/3 (Trk A/B/C), ROS1, or ALK Gene Rearrangements (Fusions)
• Esmolol Versus Dexmedetomidine During Intracranial Procedures
• The Use of Fentanyl in General Anesthesia for Craniotomy With or Without 0.5% Levobupivacaine Scalp Block
• IMRT Combined With Erlotinib for EGFR Wild Type Non-small Cell Lung Cancer With 4-10 Brain Metastases
• Vemurafenib and Cobimetinib Combination in BRAF Mutated Melanoma With Brain Metastasis
• Methoxyamine Hydrochloride, Pemetrexed Disodium, Cisplatin, and Radiation Therapy in Treating Patients With Stage IIIA-IV Non-small Cell Lung Cancer
• Nivolumab With DC Vaccines for Recurrent Brain Tumors
• Study of the IDO Pathway Inhibitor, Indoximod, and Temozolomide for Pediatric Patients With Progressive Primary Malignant Brain Tumors
• Corticosteroids + Bevacizumab vs. Corticosteroids + Placebo (BEST) for Radionecrosis After Radiosurgery for Brain Metastases
• Yellow 560 Microscope for Intraoperative Visualization of Fluorescein Stained Intracranial Lesions
• Glyburide vs Placebo as Prophylaxis Against Cerebral Edema in Patients Receiving Radiosurgery for Brain Metastases (RAD 1502/UAB 1593)
• A Study of Fotemustine(FTM) Vs FTM and Ipilimumab (IPI) or IPI and Nivolumab in Melanoma Brain Metastasis
• Methotrexate Infusion Into Fourth Ventricle in Children With Recurrent Malignant Fourth Ventricular Brain Tumors
• Buparlisib in Melanoma Patients Suffering From Brain Metastases (BUMPER)
• Using Ferumoxytol-Enhanced MRI to Measure Inflammation in Patients With Brain Tumors or Other Conditions of the CNS
• Meclofenamate in Subjects With Recurrent or Progressive Brain Metastasis From Solid Tumor Primary
• Assessment of Cognitive Functions and Quality of Life in Patients Undergoing Surgery for Supratentorial Brain Tumor
• Safety Study of Afatinib for Brain Cancer
• Use of Fluorescein Dye for the Removal of Brain Tumors
• Dasatinib, Temsirolimus, and Cyclophosphamide in Treating Patients With Advanced, Recurrent, or Refractory Solid Tumors
• Temozolomide and Concomitant Whole Brain Radiotherapy in NSCLC Patients With Brain Metastases
• Anti-PD 1 Brain Collaboration for Patients With Melanoma Brain Metastases
• Using MRI-Guided Laser Heat Ablation to Induce Disruption of the Peritumoral Blood Brain Barrier to Enhance Delivery and Efficacy of Treatment of Pediatric Brain Tumors
• PET Imaging of Intracranial Cancers With 18F-FSPG
• Perampanel in Seizure Patients With Primary Glial Brain Tumors
• Memantine Hydrochloride and Whole-Brain Radiotherapy With or Without Hippocampal Avoidance in Reducing Neurocognitive Decline in Patients With Brain Metastases
• NovoTTF-100A With Bevacizumab and Carmustine in Treating Patients With Glioblastoma Multiforme in First Relapse
• Bioequivalence Study of Temozolomide in Patients With Primary Tumors of the Central Nervous System
• Neuropharmacokinetics of Eribulin Mesylate in Treating Patients With Primary or Metastatic Brain Tumors
• Comparator-Controlled Study for EGFR(+) Patients With Multiple BMs From NSCLC (BROKE) (EGFR-epidermal Growth Factor Receptor;BM-brain Metastases)
• 1 Week Versus 6 Weeks of Levetiracetam in Surgical Brain Tumor Patients
• FLT PET/MR for Evaluation of Pseudoprogression in Patients With Brain Lesions
• Selinexor in Treating Younger Patients With Recurrent or Refractory Solid Tumors or High-Grade Gliomas
• Phase 2 Etirinotecan Pegol in Refractory Brain Metastases & Advanced Lung Cancer / Metastatic Breast Cancer
• A Study of Abemaciclib (LY2835219) in Participants With Breast Cancer, Non-small Cell Lung Cancer, or Melanoma That Has Spread to the Brain
• D2C7 for Adult Patients With Recurrent Malignant Glioma
• Phase I/II Study of MEK162 for Children With Ras/Raf Pathway Activated Tumors
• High-dose Pemetrexed to Treat Lung Adenocarcinoma With Brain Metastases
• Pilot Study of Vardenafil and Carboplatin in Patients With Gliomas and Brain Metastases
• Cabozantinib +/- Trastuzumab In Breast Cancer Patients w/ Brain Metastases
• Study of EGFR-TKI to Asymptomatic Brain Metastases of NSCLC
• Fluoro-L-Thymidine Positron Emission Tomography (FLT PET) vs. Adv. Magnetic Resonance (MR) Techniques in Recurrent Glioma
• Perifosine and Torisel (Temsirolimus) for Recurrent/Progressive Malignant Gliomas
• Phase II Study of Cobimetinib in Combination With Vemurafenib in Active Melanoma Brain Metastases
• Comparison of Two Anaesthetics on Brain During Brain Tumour Surgery
• Dose-Escalation Study of RRx-001 in Combination With Whole Brain Radiation in Subjects With Brain Metastases
• IDH1 Peptide Vaccine for Recurrent Grade II Glioma
• ALA-induced PpIX Fluorescence During Brain Tumor Resection
• Fractionated Stereotactic Radiotherapy (FSRT) in Treatment of Brain Metastases
• Bevacizumab, Etoposide and Cisplatin Followed by Whole Brain Radiotherapy in Breast Cancer With Brain Metastases
• A Study of Cabazitaxel for Patients With Breast or Lung Cancer and Recurrent or Progressive Brain Metastases - Cabazitaxel for Brain Metastases (CaBaMet)
• Therapeutic Strategies in Patients With Non-squamous Non-small Cell Lung Cancer With Brain Metastases
• Study of the Combination of KD019 and Trastuzumab in Subjects With HER2-Positive Metastatic Breast Cancer
• Treatment of Recurrent Brain Tumors: Metabolic Manipulation Combined With Radiotherapy
• Vemurafenib Combined With Whole Brain Radiation Therapy or Radiosurgery in Patients With BRAF Mutation-Positive Melanoma and Brain Metastases
• Patients With Brain Metastases From HER2-positive Breast Cancer
• A Phase II Multi-center Pilot Study of Concurrent Temozolomide and Whole Brain Irradiation in Lung Cancer and Breast Cancer Patients With Brain Metastases
• Trial of Cabozantinib (XL184) in Non-Small Cell Lung Cancer With Brain Metastases
• GEM STUDY: Radiation And Yervoy in Patients With Melanoma and Brain Metastases
• Comparison of Stroke Volume Variation-guided Normovolemic and Restrictive Fluid Management During Craniotomy: a Randomized Controlled Trial
• Simvastatin Effect on Radiation Therapy of Brain Metastases
• Lapatinib Ditosylate Before Surgery in Treating Patients With Recurrent High-Grade Glioma
• Ipilimumab Induction in Patients With Melanoma Brain Metastases Receiving Stereotactic Radiosurgery
• MK-3475 in Melanoma and NSCLC Patients With Brain Metastases
• PET-Adjusted Intensity Modulated Radiation Therapy and Combination Chemotherapy in Treating Patients With Stage II-IV Non-small Cell Lung Cancer
• International Society of Paediatric Oncology (SIOP) PNET 5 Medulloblastoma
• Combo of Abraxane, TMZ, Bevacizumab in Metastatic Melanoma With Brain Metastases
• Scalp Nerve Block and Opioid Consumption in Brain Surgery
• Study of IDO Inhibitor and Temozolomide for Adult Patients With Primary Malignant Brain Tumors
• ANG1005 in Breast Cancer Patients With Recurrent Brain Metastases
• A Phase II Study of Dacomitinib in Progressive Brain Metastases
• Study of Insulin-like Growth Factor (IGF)-Methotrexate Conjugate in the Treatment of Advanced Tumors Expressing IGF-1R
• Study to Evaluate Treatment of Dabrafenib Plus Trametinib in Subjects With BRAF Mutation-Positive Melanoma That Has Metastasized to the Brain
• Study of 4-Demethyl-4-cholesteryloxycarbonylpenclome (DM-CHOC-PEN) in Patients With Brain Tumors
• Efficacy Evaluation of Dotarem®-Enhanced MRI Compared to Gadovist®/Gadavist®-Enhanced MRI in the Diagnosis of Brain Tumors
• Yellow 560 Microscope for Intraoperative Visualization of Fluorescein Stained Intracranial Lesions
• 18F-DOPA-PET in Planning Surgery in Patients With Gliomas
• Selecting Patient-Specific Biologically Targeted Therapy for Pediatric Patients With Refractory Or Recurrent Brain Tumors
• Trametinib With or Without Whole Brain Radiation Therapy in Treating Patients With Brain Metastases
• Evaluation of Lucanthone to Whole Brain Radiation Therapy in Patients With Brain Metastases From Non-Small Cell Lung Cancer
• Small-dose Dexmedetomidine Effects on Recovery Profiles of Supratentorial Tumors Patients From General Anesthesia
• STAR Cape+BKM120 MBC With Brain Met
• Dabrafenib/Trametinib, BRAF or BRAF AND MEK Pre-op With BRAF and MEK Post-op, Phase IIB, Melanoma With Brain Mets,Biomarkers and Metabolites
• ANG1005 in Patients With Recurrent High-Grade Glioma
• Phase I Study of Safety and Immunogenicity of ADU-623
• Photodynamic Therapy (PDT) For Recurrent High Grade Gliomas
• Nicardipine vs Esmolol Craniotomy Emergence
• Pemetrexed/Cisplatin With or Without Bevacizumab in Brain Metastases From Non Squamous Non-small Cell Lung Cancer
• Gefitinib With or Without Pemetrexed/Cisplatin in Brain Metastases From Non-small Cell Lung Cancer
• Oral Pazopanib Plus Oral Topotecan Metronomic Antiangiogenic Therapy for Recurrent Glioblastoma Multiforme (A) Without Prior Bevacizumab Exposure and (B) After Failing Prior Bevacizumab
• Icotinib With Whole Brain Radiation Therapy in NSCLC Patients With Brain Metastases
• ARRY-380 + Trastuzuamab for Breast w/ Brain Mets
• Evaluation of Cabazitaxel in Patients With Brain Metastasis Secondary to Breast Cancer and NSCLC
• STAT3 Inhibitor WP1066 in Treating Patients With Recurrent Malignant Glioma or Progressive Metastatic Melanoma in the Brain
• Study of Whole-brain Irradiation With Chloroquine for Brain Metastases
• Phase Ⅲ Trial of WBRT Versus Erlotinib Concurrent Whole-brain Radiation Therapy as first-line Treatment for Patients With Multiple Brain Metastases From Non-small-cell Lung Cancer(ENTER): a Multicentre, Open-label, Randomised Study
• Temozolomide, Thalidomide, and Lomustine (TTL) in Melanoma Patients
• Valproic Acid in Childhood Progressive Brain Tumors
• Sorafenib, Valproic Acid, and Sildenafil in Treating Patients With Recurrent High-Grade Glioma
• Phase 2 Study of Neoadjuvant Vemurafenib in Melanoma Patients With Untreated Brain Metastases
• MM-398 (Nanoliposomal Irinotecan, Nal-IRI) to Determine Tumor Drug Levels and to Evaluate the Feasibility of Ferumoxytol Magnetic Resonance Imaging to Measure Tumor Associated Macrophages and to Predict Patient Response to Treatment
• Intra-operative Use of Indigo Carmine Dye for the Delineation of Ill Defined Tumor Borders Using Stereotactic Injection
• Erlotinib With Concurrent Brain Radiotherapy and Secondary Brain Radiotherapy After Recurrence With Erlotinib in NSCLC Non-increased-intracranial-pressure Symptomatic Brain Metastases
• Phase I/II Cabazitaxel for Recurrent Malignant Glioma
• Effect of Goal-directed Fluid Therapy Based on Stroke Volume Variation on Metabolic Acidosis in Patients Undergoing Brain Tumor Surgery
• Ph II SAHA and Bevacizumab for Recurrent Malignant Glioma Patients
• Methotrexate Infusion Into the Fourth Ventricle in Children With Malignant Fourth Ventricular Brain Tumors: A Pilot Study
• Phase II Trial of Chemotherapy With Temodar With Topotecan for CNS Metastasis of Solid Tumors
• IDO2 Genetic Status Informs the Neoadjuvant Efficacy of Chloroquine (CQ) in Brain Metastasis Radiotherapy
• Icotinib or Whole Brain Irradiation in EGFR-mutant Lung Cancer
• Whole Brain Radiotherapy (WBRT) With Sorafenib for Breast Cancer Brain Metastases (BCBM)
• Phase II Trial of Double Dose of Icotinib in Treating Brain Metastases From Non-small Cell Lung Cancer
• Photodynamic Therapy (PDT) for Recurrent Pediatric Brain Tumors
• GRN1005 for Brain Metastases From Breast or Lung Cancer
• A Study to Determine Safety, Tolerability and Pharmacokinetics of Oral Dabrafenib In Children and Adolescent Subjects
• Comparison of Veliparib and Whole Brain Radiation Therapy (WBRT) Versus Placebo and WBRT in Adults With Brain Metastases From Non-Small Cell Lung Cancer
• Efficacy of Tranexamic Acid in Brain Tumor Resections
• Dexanabinol in Patients With Brain Cancer
• Whole-Brain Radiation Therapy or Stereotactic Radiosurgery With or Without Lapatinib Ditosylate in Treating Patients With Brain Metastasis From HER2-Positive Breast Cancer
• Vorinostat and Concurrent Whole Brain Radiotherapy for Brain Metastasis
• Phase I/II Bevacizumab Versus Bevacizumab Plus TPI 287 for Recurrent Glioblastoma
• Erlotinib Plus Pemetrexed to Treat Lung Adenocarcinoma With Brain Metastases
• Pilot Study Effect of Sulfasalazine on Glutamate Levels by(Magnetic Resonance Spectroscopy)MRS in Patients With Glioma
• Comparison of Dexmedetomidine and Propofol-Remifentanil Conscious Sedation for Awake Craniotomy for Tumor Surgery
• PET/CT Evaluation of Primary and Metastatic Brain Tumors With a Novel Radioiodinated Phospholipid Ether Analogue I-NM404
• Irinotecan Combination Chemotherapy for Refractory or Relapsed Brain Tumor in Children and Adolescents
• Metformin in Children With Relapsed or Refractory Solid Tumors
• Vaccine Therapy With or Without Sirolimus in Treating Patients With NY-ESO-1 Expressing Solid Tumors
• Safety and Efficacy of PF-299804 (Dacomitinib), a Pan-HER Irreversible Inhibitor, in Patients With Recurrent Glioblastoma With EGFR Amplification or Presence of EGFRvIII Mutation. A Phase II CT.
• Whole Brain Radiation With or Without Erlotinib for Brain Metastases From Non-Small Cell Lung Cancer
• Icotinib Combined With WBRT For NSCLC Patients With Brain Metastases and EGFR Mutation
• PET/CT Imaging of Malignant Brain Tumors With 124I-NM404
• Icotinib Combined With Whole Brain Radiotherapy in Treating Multiple Brain Metastases From Non-Small Cell Lung Cancer
• Evaluation of the Use of Trental and Vitamin E For Prophylaxis of Radiation Necrosis
• Auto Transplant for High Risk or Relapsed Solid or CNS Tumors
• Convection-Enhanced Delivery of 124I-Omburtamab for Patients With Non-Progressive Diffuse Pontine Gliomas Previously Treated With External Beam Radiation Therapy
• GRN1005 in Non-Small Cell Lung Cancer (NSCLC) Patients With Brain Metastases (GRABM-L)
• HKI-272 for HER2-Positive Breast Cancer and Brain Metastases
• The EC90 of Remifentanil Blunting Hemodynamic Changes to Head Fixation
• GRN1005 Alone or in Combination With Trastuzumab in Breast Cancer Patients With Brain Metastases
• Safety Study of VAL-083 in Patients With Recurrent Malignant Glioma
• Safety and Imaging Study of GC1008 in Glioma
• CAR T Cell Receptor Immunotherapy Targeting EGFRvIII for Patients With Malignant Gliomas Expressing EGFRvIII
• More Complete Removal of Malignant Brain Tumors by Fluorescence-Guided Surgery
• Lux-Breast 3; Afatinib Alone or in Combination With Vinorelbine in Patients With Human Epidermal Growth Factor Receptor 2 (HER2) Positive Breast Cancer Suffering From Brain Metastases
• Phase I-II Everolimus and Sorafenib in Recurrent High-Grade Gliomas
• Lacosamide in Preventing Seizures in Participants With Malignant Glioma
• Temozolomide, Memantine Hydrochloride, Mefloquine, and Metformin Hydrochloride in Treating Patients With Glioblastoma Multiforme After Radiation Therapy
• Continuous Endostar Infusion Combined With Radiotherapy in Patients With Brain Metastases
• A Study of Aminolevulinic Acid (ALA) to Enhance Visualization and Resection of Malignant Glial Tumors of the Brain
• An Open-label, Phase I/IIa, Dose Escalating Study of 2B3-101 in Patients With Solid Tumors and Brain Metastases or Recurrent Malignant Glioma.
• Modafinil in Treating Children With Memory and Attention Problems Caused by Cancer Treatment for a Brain Tumor
• A Study of Vemurafenib in Metastatic Melanoma Participants With Brain Metastases
• High-Dose Vorinostat and Fractionated Stereotactic Body Radiation Therapy in Treating Patients With Recurrent Glioma
• Tolerability Study of Xerecept® in Pediatric Patients
• Assess the Efficacy of Whole Brain Radiation Therapy in Lung Cancer Patients With Brain Metastasis
• Tandem High Dose Chemotherapy and Autologous Stem Cell Rescue for High Risk Pediatric Brain Tumors
• Safety Evaluation of a Combination of Brain Radiation Therapy and Bevacizumab (Avastin®) for Treatment of Brain Metastasis
• Panobinostat and Stereotactic Radiation Therapy in Treating Patients With Brain Tumors
• Electrochemotherapy as a Palliative Treatment for Brain Metastases
• 18-F-Fluoroacetate as PET Imaging Agent
• A Study Of Everolimus, Trastuzumab And Vinorelbine In HER2-Positive Breast Cancer Brain Metastases
• Bevacizumab With Etoposide and Cisplatin in Breast Cancer Patients With Brain and/or Leptomeningeal Metastasis
• Sorafenib Tosylate and Stereotactic Radiosurgery in Treating Patients With Brain Metastases
• RO4929097 in Treating Patients With Recurrent Invasive Gliomas
• A Study of GSK2118436 in BRAF Mutant Metastatic Melanoma to the Brain
• PET Imaging of Patients With Melanoma and Malignant Brain Tumors Using an 124I-labeled cRGDY Silica Nanomolecular Particle Tracer: A Microdosing Study
• Satraplatin in Children and Young Adults With Refractory Solid Tumors Including Brain Tumors
• EGFR Inhibition Using Weekly Erlotinib for Recurrent Malignant Gliomas
• A Study of RO5185426 in Previously Treated Melanoma Patients With Brain Metastases
• Vaccine Therapy and Sargramostim in Treating Patients With Malignant Glioma
• Assessment of Primary and Metastatic Brain Tumor Hypoxia With Fluoromisonidazole, FDG and Water
• FLT-PET Imaging of Brain Tumors in Children
• Temozolomide in Elderly Patients With KPS < 70
• Personalized Translational Platform for Biomarker Discovery in Brain Tumors
• RO4929097 in Children With Relapsed/Refractory Solid or CNS Tumors, Lymphoma, or T-Cell Leukemia
• Bafetinib in Treating Patients With Recurrent High-Grade Glioma or Brain Metastases
• To Evaluate the Safety, Activity and Pharmacokinetics of Marqibo in Children and Adolescents With Refractory Cancer
• Lapatinib and WBRT for Patients With Brain Metastases From Lung or Breast Tumors
• RO4929097 and Whole-Brain Radiation Therapy or Stereotactic Radiosurgery in Treating Patients With Brain Metastases From Breast Cancer
• A Trial of Poly-ICLC in the Management of Recurrent Pediatric Low Grade Gliomas
• A Study Evaluating INIPARIB in Combination With Chemotherapy to Treat Triple Negative Breast Cancer Brain Metastasis
• A Pilot Feasibility Study of Oral 5-Fluorocytosine and Genetically-Modified Neural Stem Cells Expressing E.Coli Cytosine Deaminase for Treatment of Recurrent High Grade Gliomas
• Vaccination With Dendritic Cells Loaded With Brain Tumor Stem Cells for Progressive Malignant Brain Tumor
• Pioglitazone Hydrochloride in Preventing Radiation-Induced Cognitive Dysfunction in Treating Patients With Brain Tumors
• Aminolevulinic Acid During Surgery in Treating Patients With Malignant Brain Tumors
• Gamma-Secretase Inhibitor RO4929097 and Cediranib Maleate in Treating Patients With Advanced Solid Tumors
• A Phase I Study of Pazopanib as a Single Agent for Children With Refractory Solid Tumors
• A Study of the Specificity and Sensitivity of 5- Aminolevulinic Acid (ALA) Fluorescence in Malignant Brain Tumors
• Cilengitide and Sunitinib Malate in Treating Patients With Advanced Solid Tumors or Glioblastoma Multiforme
• Phase 1-2 of Temozolomide and Hypofractionated Radiotherapy in Tx of Supratentorial Glioblastoma Multiform
• Safety Study of Aminolevulinic Acid (ALA) to Enhance Visualization and Resection of Tumors of the Brain
• TPI 287 in Patients With Recurrent Glioblastoma Multiforme
• Study of the Safety and Efficacy of Dichloroacetate (DCA) in Glioblastoma and Other Recurrent Brain Tumors
• Phase I / II Vorinostat, Erlotinib and Temozolomide for Recurrent Glioblastoma Multiforme (GBM)
• Temodar (Temozolomide), Bevacizumab, Lithium and Radiation for High Grade Glioma
• Effects of Methylphenidate on Attention Deficits in Childhood Cancer Survivors
• Ritonavir and Lopinavir in Treating Patients With Progressive or Recurrent High-Grade Glioma
• Radiosurgery Plus Bevacizumab in Glioblastoma
• Brain Metastasis in Breast Cancer Patients
• Standard Dose Bevacizumab Versus Low Dose Bevacizumab Plus Lomustine (CCNU) for Recurrent Glioblastoma Multiforme (GBM)
• Temsirolimus and Perifosine in Treating Patients With Recurrent or Progressive Malignant Glioma
• Comparison of Two Doses of Mannitol on Brain Relaxation During Supratentorial Craniotomy
• Armodafinil in Treating Fatigue Caused By Radiation Therapy in Patients With Primary Brain Tumors
• Riluzole and Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases
• Whole Brain Radiotherapy With or Without Temozolomide at Daily Fixed-dose for Brain Metastases Treatment
• Intercontinental Multidisciplinary Registry and Treatment Optimization Study for Choroid Plexus Tumors
• Carboplatin and Bevacizumab for Progressive Breast Cancer Brain Metastases
• Efficiency of Two Glucose Sampling Protocols for Maintenance of Euglycemia
• Melphalan, Carboplatin, Mannitol, and Sodium Thiosulfate in Treating Patients With Recurrent or Progressive CNS Embryonal or Germ Cell Tumors
• Stereotactic Radiosurgery With Sunitinib for Brain Metastases
• Cediranib Maleate and Cilengitide in Treating Patients With Progressive or Recurrent Glioblastoma
• Image-Guided Stereotactic Biopsy of High Grade Gliomas
• DSC-MRI With Ferumoxytol and DCE-MRI With Gadolinium in Imaging Vascular Properties in Younger Patients With Brain Tumors
• A Study of the Specificity and Sensitivity of 5-ALA Fluorescence in Malignant Brain Tumors
• A Study of Whole Brain Radiation Therapy and Capecitabine in Breast Cancer Participants With Newly Diagnosed Brain Metastasis
• Lapatinib Ditosylate and Capecitabine in Treating Patients With Stage IV Breast Cancer and Brain Metastases
• A Pilot Study to Evaluate Efficacy and Safety of Clevidipine in Neurosurgical Patients
• Assessment of Systemically Administered Torisel Delivery to Brain Tumors by Intratumoral Microdialysis
• Phase I Vorinostat Concurrent With Stereotactic Radiosurgery (SRS) in Brain Metastases From Non-Small Cell Lung Cancer
• Cediranib Maleate and Whole Brain Radiation Therapy in Patients With Brain Metastases From Non-Small Cell Lung Cancer
• Sunitinib Malate After Stereotactic Radiosurgery in Treating Patients With Newly Diagnosed Brain Metastases
• Neuradiab® Combined With Bevacizumab (Avastin) Therapy in Patients With Recurrent Glioblastoma Multiforme
• Autologous Dendritic Cells Pulsed With Autologous Apoptotic Tumor Cells Administered to Patients With Brain Tumors
• Everolimus and Whole-Brain Radiation Therapy in Treating Patients With Brain Metastasis From Non-Small Cell Lung Cancer
• Cilengitide and Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases From Lung Cancer
• Bevacizumab and Lapatinib in Children With Recurrent or Refractory Ependymoma
• An Open Label Dose Escalation Safety Study of Convection-Enhanced Delivery of IL13-PE38QQR in Patients With Progressive Pediatric Diffuse Infiltrating Brainstem Glioma and Supratentorial High-grade Glioma
• Study Bendamustine Concurrent Whole Brain Radiation Brain Metastases From Solid Tumors
• Radiation Therapy With or Without Temozolomide in Treating Women With Brain Metastases and Breast Cancer
• A Study of Nimotuzumab in Combination With Radiation Therapy in Patients With Brain Metastases
• Tarceva With Whole Brain Radiation Therapy - Brain Mets From Non-Small Cell Lung Cancer
• Fluorescence Guided Resection of Brain Tumors
• Study to Demonstrate the Safety of WBR Administered at the Same Time as Intrathecal Liposomal Cytarabine (DepoCyte®) Versus Intrathecal Liposomal Cytarabine (DepoCyte®) Administered After WBR for the Treatment of Solid Tumour Neoplastic Meningitis
• Methionine PET/CT Studies In Patients With Cancer
• Study of the Combination of Vorinostat and Radiation Therapy for the Treatment of Patients With Brain Metastases
• Bendamustine and Radiation Therapy in Treating Patients With Brain Metastases Caused by Solid Tumors
• Study of Busulfan for Refractory Central Nervous System (CNS) Tumors
• Study to Evaluate the Efficacy and Safety of Temozolomide in Subjects With Brain Metastases of Either Malignant Melanoma, Breast, or Non-small Cell Lung Cancer (P02064)
• Everolimus in Treating Patients With Recurrent Low-Grade Glioma
• Dose-Dense Temozolomide + Lapatinib for Recurrent Ependymoma
• Bendamustine Hydrochloride in Treating Patients With Recurrent or Progressive Anaplastic Glioma
• Everolimus in Treating Patients With Recurrent Low-Grade Glioma
• Investigate the Maximum Tolerated Dose of Vandetanib and Concurrent Whole Brain Radiotherapy (WBRT) in Patients With Non-small Cell Lung Cancer (NSCLC) and Brain Metastases
• Evaluation of the Efficacy and Safety of [18F]-ML-10, as a PET Imaging Radiotracer, in Early Detection of Response of Brain Metastases of Solid Tumors to Radiation Therapy.
• DNX-2401 (Formerly Known as Delta-24-RGD-4C) for Recurrent Malignant Gliomas
• A Study of Avastin (Bevacizumab) in Patients With Non-Squamous Non-Small Cell Lung Cancer With Asymptomatic Untreated Brain Metastasis
• A Feasibility, Dose-Escalation Study Using Intracerebral Microdialysis to Assess the Neuropharmacodynamics of Temsirolimus in Patients With Primary or Metastatic Brain Tumors
• Assessing Dynamic Magnetic Resonance (MR) Imaging in Patients With Recurrent High Grade Glioma Receiving Chemotherapy
• PPX, Temozolomide, and Concurrent Radiation for Newly Diagnosed Brain Tumors
• Therapy Optimization Trial for the Treatment of Relapsed or Refractory Brain Tumors in Children
• Pemetrexed Plus Cisplatin for Brain Metastasis of Advanced Non - Small Cell Lung Cancer (NSCLC)
• Stereotactic Radiosurgery and Erlotinib in Treating Patients With Non-Small Cell Lung Cancer and Brain Metastases
• Study of Temozolomide to Treat Newly Diagnosed Brain Metastases
• Combination of Hydroxyurea and Verapamil for Refractory Meningiomas
• 18F ML-10 for Early Detection of Response of Brain Metastases to SRS
• Imaging Study of XERECEPT® Treatment for Peritumoral Brain Edema (PBE)
• Magnevist (SH L 451A) Intra-individual Dose Comparison Study in Patients With Brain Metastasis
• Study of Aminolevulinic Acid to Enhance Visualization and Resection of Malignant Glial Tumors of the Brain
• Efficacy of Erlotinib for Brain Metastasis of Non-Small Cell Lung Cancer
• Imaging of Intravenous (IV) Combidex to Brain, Intra-cerebral Tumors and in Central Nervous System (CNS) Inflammation
• Ferumoxytol- and Gadolinium-Labeled MRI in Measuring Tumors Before or After Treatment in Patients With Primary or Metastatic Brain Tumors
• A Phase I Study of ABT-888 in Combination With Conventional Whole Brain Radiation Therapy (WBRT) in Cancer Patients With Brain Metastases
• Vaccine Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
• Combination of Sorafenib and Radiation for Brain Metastases and Primary Brain Tumors
• Temozolomide as a Prophylaxis Against Brain Recurrence in Participants With Metastatic Breast Cancer (P05225 AM2)
• External-Beam Radiation Therapy With or Without Indinavir and Ritonavir in Treating Patients With Brain Metastases
• Aloxi for Prevention of Chemotherapy Induced Nausea and Vomiting in Malignant Glioma Patients Receiving Irinotecan With Bevacizumab
• A Phase I Study of AdV-tk + Prodrug Therapy in Combination With Radiation Therapy for Pediatric Brain Tumors
• Levetiracetam or Pregabalin in Treating Seizures in Patients Undergoing Chemotherapy and/or Radiation Therapy For Primary Brain Tumors
• Innohep for Prophylaxis of Venous Thromboembolism in Brain Tumor Patients
• Chemotherapy, Radiation Therapy, and Vaccine Therapy With Basiliximab in Treating Patients With Glioblastoma Multiforme That Has Been Removed by Surgery
• Evaluation of Tumor Response to Ipilimumab in the Treatment of Melanoma With Brain Metastases
• Lapatinib and Temozolomide for the Treatment of Progressive Brain Disease in HER-2 Positive Breast Cancer
• Efficacy of Gefitinib for Brain Metastasis of Non-Small Cell Lung Cancer
• Risk-Adapted Therapy for Young Children With Embryonal Brain Tumors, Choroid Plexus Carcinoma, High Grade Glioma or Ependymoma
• Avastin in Combination With Radiation (XRT) & Temozolomide, Followed by Avastin, Temozolomide and Irinotecan for Glioblastoma (GBM) and Gliosarcomas
• Imaging Brain Tumors With FACBC and Methionine
• Clinical and Molecular-Metabolic Phase II Trial of Perifosine for Recurrent/Progressive Malignant Gliomas
• A Phase I Study of ABT 510 for Newly Diagnosed Glioblastoma Multiforme
• Phase II Study of Gamma Knife Radiosurgery and Temozolomide for Brain Metastases
• Learning Impairments Among Survivors of Childhood Cancer
• Efficacy of Protracted Temozolomide in Patients With Progressive High Grade Glioma
• Trial of Levetiracetam in Patients With Primary Brain Tumors and Symptomatic Seizures Who Undergo Surgery
• [F-18]Fluoro-DOPA PET Imaging of Brain Tumors in Children
• Intravenous Anesthesia Versus Anesthesia With Volatile Agents in Elective Craniotomy for Tumors
• WBRT & Erlotinib in Advanced NSCLC and Brain Metastases
• Phase I, Open Label, Single Center Safety Study of [F-18]FLT
• A Phase 1, Open-Label, Dose Escalation Study of ANG1005 in Patients With Advanced Solid Tumors and Metastatic Brain Cancer
• RTA 744 in Breast Cancer Patients With Progression of Previously Irradiated Brain Metastases
• Safety Study of Radiotherapy and Concurrent Erlotinib (Tarceva®) for Brain Metastases From a Non-Small Cell Lung Cancer
• Temozolomide,Thiotepa and Carboplatin With Autologous Stem Cell Rescue Followed by 13-cis-retinoic Acid in Patients With Recurrent/Refractory Malignant Brain Tumors
• Temozolomide, Thalidomide, and Lomustine (TTL) in Melanoma Patients
• Exploratory Study, Evaluating the Treatment Effect of Surgery Plus GLIADEL® Wafer in Patients With Metastatic Brain Cancer
• SH L 562BB Phase II/III Dose Justification and Gadoteridol-controlled Comparative Study
• Valproate and Etoposide for Patients With Neuronal Tumors and Brain Metastases
• RTA 744 Injection in Patients With Leptomeningeal Disease
• 6-TG, Capecitabine and Celecoxib Plus TMZ or CCNU for Anaplastic Glioma Patients
• Phase I : Cediranib in Combination With Lomustine Chemotherapy in Recurrent Malignant Brain Tumour
• ZK219477 (Sagopilone) in Patients With Breast Cancer and Brain Metastases
• Bevacizumab in Reducing CNS Side Effects in Patients Who Have Undergone Radiation Therapy to the Brain for Primary Brain Tumor, Meningioma, or Head and Neck Cancer
• Combined Levothyroxine/Liothyronine Supplementation in Hypothyroid Patients With Brain Tumors
• A Phase 1 / 2 Dose Escalation Study of Locally-Administered OncoGel™ in Subjects With Recurrent Glioma
• Nuclear Imaging of Human CSF Flow Using Ga-67 Citrate and In-111 DTPA
• A Phase II Safety and Tolerability Study of Bevacizumab When Added to Single-agent Chemotherapy to Treat Patient With Breast Cancer Metastatic to Brain
• Lapatinib in Combination With Radiation Therapy in Patients With Brain Metastases From HER2-Positive Breast Cancer
• Ph I Study of Lithium During Whole Brain Radiotherapy For Patients With Brain Metastases
• Liposomal Doxorubicin (Lipo-Dox) in Patients With Brain Metastasis From Breast Cancer
• Bevacizumab and Irinotecan for Patients With Primary Brain Tumors and Progression After Standard Therapy
• Donepezil in Treating Young Patients With Primary Brain Tumors Previously Treated With Radiation Therapy to the Brain
• Phase I Study of Temozolomide, Valproic Acid and Radiation Therapy in Patients With Brain Metastases
• Brain Metastases In ErbB2-Positive Breast Cancer
• Bevacizumab and Irinotecan or Temozolomide in Treating Patients With Recurrent or Refractory Glioblastoma Multiforme or Gliosarcoma
• Radiotherapy for Malignant Astrocytomas in the Elderly
• Low-dose Temozolomide for 2 Weeks on Brain Tumor Enzyme in Patients With Gliomas (P04602 AM1) (Completed)
• Dasatinib in Treating Patients With Recurrent Glioblastoma Multiforme or Gliosarcoma
• Effects of Methylphenidate Versus Sustained Release Methylphenidate on Cognitive Functioning
• Safety Study of Tarceva in Children With Refractory and Relapsed Malignant Brain Tumors and Newly Diagnosed Brain Stem Glioma
• Levetiracetam in Treating Patients With Seizures Caused by Brain Metastases
• Study of Enzastaurin Versus Placebo in the Treatment of Patients With Brain Metastases of Lung Cancer, After Whole Brain Radiation Therapy
• Multihance at 3 Tesla (3T) in Brain Tumors
• Multiple Dose Study of MPC-6827 in Subjects With Refractory Brain Metastases
• Combination Chemotherapy With or Without Etoposide Followed By an Autologous Stem Cell Transplant in Treating Young Patients With Previously Untreated Malignant Brain Tumors
• Oral HYCAMTIN Plus Whole Brain Radiation Therapy In Treatment Of Brain Metastases Resulting From Non-Small Lung Cancer
• Irinotecan and Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases From Solid Tumors
• Erlotinib in Treating Patients With Recurrent Glioblastoma Multiforme or Gliosarcoma
• QOL-Stereotactic RadioSurgery, Temozolomide + Erlotinib-Rx of 1-3 Brain Metastases in NSCLC
• Tandutinib in Treating Patients With Recurrent or Progressive Glioblastoma
• Study Tests The Safety And Effectiveness Of SU011248 In Patients With Non-Small Cell Lung Cancer Having Brain Metastases
• Donepezil in Treating Patients Who Have Undergone Radiation Therapy for Brain Tumors
• Gliadel Wafer and O6-Benzylguanine in Treating Patients With Recurrent Glioblastoma Multiforme
• Carboplatin and Temozolomide (Temodar) for Recurrent and Symptomatic Residual Brain Metastases
• Erlotinib Alone or in Combination With Radiation Therapy in Treating Young Patients With Refractory or Relapsed Malignant Brain Tumors or Newly Diagnosed Brain Stem Glioma
• Efficacy of Prophylactic Itraconazole in High-Dose Chemotherapy and Autologous Hematopoietic Stem Cell Transplantation
• Sorafenib Tosylate and Temsirolimus in Treating Patients With Recurrent Glioblastoma
• A Trial Using Velcade Plus Chemoradiation for Central Nervous System, Head and Neck, and Cervical Cancer Patients
• AZD2171 in Treating Young Patients With Recurrent, Progressive, or Refractory Primary CNS Tumors
• A Pilot Study of Dronabinol for Adult Patients With Primary Gliomas
• Thiotepa and Radiation Therapy in Treating Young Patients With Newly Diagnosed Malignant Brain Tumors
• A Study of Bevacizumab in Combination With First- or Second-Line Therapy in Subjects With Treated Brain Metastases Due to Non-Squamous NSCLC (PASSPORT)
• Safety Study of Intracerebral Topotecan for Recurrent Brain Tumors
• Talabostat Combined With Temozolomide or Carboplatin in Treating Young Patients With Relapsed or Refractory Brain Tumors or Other Solid Tumors
• Carboplatin, Melphalan, Etoposide Phosphate, Mannitol, and Sodium Thiosulfate in Treating Patients With Previously Treated Brain Tumors
• Valproic Acid With Temozolomide and Radiation Therapy to Treat Brain Tumors
• Zoledronate in Preventing Osteoporosis in Patients With Primary Malignant Glioma
• Combination Chemotherapy With or Without Radiation Therapy in Treating Children With Brain Tumors
• Whole-Brain Radiation Therapy and Pemetrexed in Treating Patients With Brain Metastases From Non-Small Cell Lung Cancer
• Pemetrexed Disodium in Treating Patients With Recurrent Malignant Gliomas, Primary CNS Lymphoma, or Brain Metastases
• Comparison Study of WBRT and SRS Alone Versus With Temozolomide or Erlotinib in Patients With Brain Metastases of NSCLC
• Vorinostat and Temozolomide in Treating Patients With Malignant Gliomas
• Chemotherapy and HAART to Treat AIDS-related Primary Brain Lymphoma
• Lapatinib for Brain Metastases In ErbB2-Positive Breast Cancer
• Safety Study of 2DG With Stereotactic Radiosurgery
• Fluorescence-guided Resection of Malignant Gliomas With 5-Aminolevulinic Acid
• Radiation Therapy Combined With Either Gefitinib or Temozolomide in Pats With NSCLC and Brain Metastases
• Acetylcysteine, Mannitol, Combination Chemotherapy, and Sodium Thiosulfate in Treating Children With Malignant Brain Tumors
• Iressa in the Treatment of Brain Metastases From Non Small Cell Lung Cancer
• Capecitabine and Pegylated Interferon Alfa-2a in Treating Patients With Recurrent or Progressive Brain Metastases Due to Breast Cancer
• XERECEPT® (hCRF) for Primary Glioma Patients Requiring Dexamethasone to Treat Peritumoral Brain Edema
• An Open-Labeled, Extended-Use of XERECEPT (hCRF) for Patients in Studies NTI 0302, 0303, or Other Designated Studies
• Study of Patupilone in Patients With Brain Metastasis From Non-small Cell Lung Cancer
• Study on Amino Acid Uptake in Brain Tumors
• Hypertonic Saline 75% vs Mannitol 20%
• Dexamethasone for Palliation - Brain Metastases
• Everolimus for Treating Pediatric Patients With Recurrent or Refractory Tumors
• Phase I Trial of Arsenic Trioxide and Stereotactic Radiotherapy for Recurrent Malignant Glioma
• High Risk Primitive Neuroectodermal (PNET) Brain Tumors in Childhood
• Thalomid and Carboplatin for the Treatment of Pediatric Brain Stem Glioma
• Dalteparin Low Molecular Weight Heparin for Primary Prophylaxis of Venous Thromboembolism in Brain Tumour Patients
• Study of Motexafin Gadolinium With Whole Brain Radiation Therapy Followed by Stereotactic Radiosurgery Boost in the Treatment of Patients With Brain Metastases
• Positron Emission Tomography Using Fluorine F 18 EF5 to Find Oxygen in Tumor Cells of Patients Who Are Undergoing Surgery or Biopsy for Newly Diagnosed Brain Tumors
• GW572016 to Treat Recurrent Malignant Brain Tumors
• Ferumoxytol in Improving MR Imaging in Patients With High-Grade Brain Tumors or Cerebral Metastases
• Lonafarnib and Temozolomide in Treating Patients With Glioblastoma Multiforme That Is Recurrent or Did Not Respond to Previous Treatment With Temozolomide
• VNP40101M in Treating Young Patients With Recurrent, Progressive, or Refractory Primary Brain Tumors
• Lapatinib in Treating Brain Metastases in Patients With Stage IV Breast Cancer and Brain Metastases
• Radiation Therapy and Stereotactic Radiosurgery With or Without Temozolomide or Erlotinib in Treating Patients With Brain Metastases Secondary to Non-Small Cell Lung Cancer
• XERECEPT® (hCRF) for Patients Requiring Dexamethasone to Treat Edema Associated With Brain Tumors
• Whole Brain Radiation Therapy With Oxygen, With or Without RSR13, in Women With Brain Metastases From Breast Cancer
• Temozolomide and Radiation Therapy in Treating Patients With Brain Metastasis Secondary to Non-Small Cell Lung Cancer
• A Study of Motexafin Gadolinium and Temozolomide for the Treatment of Malignant Gliomas
• Erlotinib and Temozolomide in Treating Young Patients With Recurrent or Refractory Solid Tumors
• Temozolomide for Treatment of Brain Metastases From Non-Small Cell Lung Cancer (Study P03247)
• Phase II Studies Of Donepezil And Ginkgo Biloba In Irradiated Brain Tumor
• Cyproheptadine and Megestrol in Preventing Weight Loss in Children With Cachexia Caused By Cancer or Cancer Treatment
• Cilengitide in Treating Children With Refractory Primary Brain Tumors
• Study of Karenitecin (BNP1350) in Patients With Brain Tumors
• Study of Neurologic Progression With Motexafin Gadolinium and Radiation Therapy (SMART)
• Temozolomide and O6-Benzylguanine in Treating Children With Recurrent Brain Tumors
• Radiation Therapy Plus Thalidomide and Temozolomide in Treating Patients With Newly Diagnosed Brain Metastases
• Imatinib Mesylate in Treating Patients With Recurrent Brain Tumor
• Study of a Drug [DCVax®-L] to Treat Newly Diagnosed GBM Brain Cancer
• Study of Systemic and Spinal Chemotherapy Followed by Radiation for Infants With Brain Tumors
• Safety and Tolerability Study of 131I-TM-601 to Treat Adult Patients With Recurrent Glioma.
• Study of 111In-DAC as an Medical Imaging Agent for Lung Cancer and Brain Cancer Consistent With Metastatic Lung Cancer
• Phase I Trial of Intramural Injection of DTI-015 for Recurrent Malignant Gliomas
• Study of Vioxx and Radiation Therapy for Brainstem Glioma
• Study of Temozolomide in the Treatment of Brain Metastasis From Non-small-cell Lung Cancer (Study P02143)
• Radiation Therapy With or Without Thalidomide in Treating Patients With Brain Metastases
• Melatonin and Radiation Therapy in Treating Patients With Brain Metastases
• Methylphenidate to Improve Quality of Life in Patients Undergoing Radiation Therapy for Brain Tumors
• Temozolomide and Vinorelbine in Treating Patients With Recurrent Brain Metastases
• Liposomal Doxorubicin in Treating Children With Refractory Solid Tumors
• Lobradimil and Carboplatin in Treating Children With Brain Tumors
• SCH 66336 in Treating Children With Recurrent or Progressive Brain Tumors
• Phenylbutyrate to Treat Children With Progressive or Recurrent Brain Tumors
• SU5416 in Treating Children With Recurrent or Progressive Brain Tumors
• Temozolomide in Treating Patients With Brain Metastases
• Radiation Therapy With or Without RSR13 in Treating Patients With Brain Metastases
• Phase II Study of Carmustine, Streptozocin, and Mercaptopurine for Refractory or Recurrent Brain Neoplasms
• Carmustine Implants in Treating Patients With Brain Metastases
• Radiation Therapy Plus Gadolinium Texaphyrin in Treating Patients With Brain Metastases
• Radiolabeled Monoclonal Antibody Therapy After Radiation Therapy in Treating Patients With Primary Brain Tumors
• Antineoplaston Therapy in Treating Children With Primary Malignant Brain Tumors
• Antineoplaston Therapy in Treating Patients With Primary Malignant Brain Tumors
• Antineoplaston Therapy in Treating Children With Brain Tumors
• Antineoplaston Therapy in Treating Patients With Brain Tumors
• Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Brain Tumor
• Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Infants With Malignant Brain or Spinal Cord Tumors
• Combination Chemotherapy in Treating Children With Progressive Brain Tumors
• Gene Therapy in Treating Patients With Primary Brain Tumors
• Photodynamic Therapy With Porfimer Sodium in Treating Patients With Refractory Brain Tumors
• Suramin in Treating Patients With Recurrent Primary Brain Tumors
• Combination Chemotherapy Followed by Bone Marrow and/or Peripheral Stem Cell Transplantation in Treating Patients With Recurrent Medulloblastoma or CNS Germ Cell Tumors
• PET Scan of Brain Metabolism in Relation to Age and Disease
• Phase I and Pharmacokinetic Trial of Phenylbutyrate Given as a Continuous Infusion in Pediatric Patients With Refractory Malignancy
• A Pediatric Phase I Trial of RMP-7 and Carboplatin in Brain Tumors
• Gene Therapy for the Treatment of Brain Tumors