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Clinical Trials for Malaria

• Effectiveness and Cost-effectiveness of Integrated Model for Malaria and Helminth Control
• Parasite Clearance and Protection From Infection (PCPI) in Cameroon
• In-vivo Transmission Model in Semi-immune Adults
• Parasite Clearance and Protection From Infection (PCPI) in Zambia
• A Revised Tafenoquine Dose to Improve Radical Cure for Vivax Malaria
• Preventing Malaria in School Children to Protect the Whole Community in Rural Blantyre District, Malawi
• Test Efficacy Study on the Recommended Antimalarial Drugs in the Democratic Republic of the Congo
• Mass Vaccine and Drug Administration, Bangladesh
• Efficacy, Safety, and PK of M5717 in Combination With Pyronaridine as Chemoprevention in Adults and Adolescents With Asymptomatic Plasmodium Falciparum Infection (CAPTURE-2)
• Innovative Intermittent Preventive Treatment Approaches to Reduce Malaria Burden in School-age Children in Burkina Faso
• Piperaquine Granule Formulation Relative Bioavailability and Food Effect Study in Healthy Volunteers.
• Study of the Plasmodium Vivax Transmission-blocking Vaccine Pvs230D1-EPA/Matrix-M to Assess Safety, Immunogenicity, and Transmission-blocking Activity in Healthy Malaria-naive Adults
• Pan-Malaria Transmission-Blocking Vaccine AnAPN1
• Dihydroartemisinin-piperaquine for Seasonal Malaria Chemoprophylaxis in Tanzania
• Efficacy, Safety and Tolerability of KLU156 in Adults and Children ≥ 5 kg Body Weight With Uncomplicated P. Falciparum Malaria
• Momordica Charantia and Dihydroartemisinin-piperaquined-primaquine for Uncomplicated Plasmodium Falciparum Malaria Patients in Southwest Sumba Regency
• DHA-PPQ vs CHQ With Tafenoquine for P. Vivax Mono-infection
• Triple Artemisinin-based Combination Therapy for Delaying Drug Resistance Development - a Randomized Clinical Trial
• Improving Neonatal Health Through Rapid Malaria Testing in Early Pregnancy With High-Sensitivity Diagnostics
• Platform Study to Evaluate the Efficacy and Safety of Anti-malarial Agents in Patients With Uncomplicated Plasmodium Falciparum Malaria
• Exposure-Response Evaluation of IV Artesunate in Children With Severe Malaria
• FocaL Mass Drug Administration for Vivax Malaria Elimination
• Phase IIa Proof of Concept Study of M5717-Pyronaridine in Adults and Adolescents With Acute Uncomplicated Plasmodium Falciparum Malaria (CAPTURE 1)
• Phase 1 Safety Evaluation of PfSPZ Vaccine in Pregnant Women in Mali (MalVIP1)
• Ivermectin-artemisinin Combination Therapy for Eradication of Malaria
• Child Health and Infection With Low Density (CHILD) Malaria
• Radical CUREfor MAlaria Among Highly Mobile and Hard-to-reach Populations in the Guyanese Shield
• First-in-Human Study to Assess the Safety, Tolerability and Pharmacokinetics of MMV367
• Chemoprevention Efficacy Study in Burkina Faso
• DON in Pediatric Cerebral Malaria: A Phase I/IIa Dose-Escalation Safety Study: Part 1-Adult Arm
• Effectiveness, Feasibility and Acceptability of Seasonal Malaria Chemoprevention in Aweil South County in South Sudan
• Comparing Safety and Protective Efficacy of Vaccine Candidate PfSPZ-CVac and MVA ME-TRAP/ ChAd63 ME-TRAP in Adults
• Sulfadoxine-pyrimethamine Plus Dihydroartemisinin-piperaquine for Intermittent Preventive Treatment in Pregnancy
• Anti-malaria MAb in Kenyan Children
• Feasibility and Safety of Combining Anti-malarial With Deworming Drugs in African Children
• In Vivo Efficacy of Artemether-Lumefantrine, Amodiaquine-Artesunate, Dihydroartemisinin-Piperaquine, and Pironaridine-Artesunate in Mozambique
• Efficacy and Safety of Artemether-Lumefantrine and Dihydroartemisinin-Piperaquine in Cameroon
• Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Efavirenz
• Effectiveness and Chemoprevention Efficacy of Implementing Seasonal Malaria Chemoprevention in Karamoja Region, Uganda
• Intermittent Preventive Treatment With Dihydroartemisinin-piperaquine in Papua, Indonesia
• A PK/PD Study of Pyronaridine in Healthy Adult Participants Infected With Blood Stage Malaria
• Safety and Immunogenicity of the Malaria Vaccine, R21/MatrixM, in Healthy Thai Adults
• Comparing Chemoprevention Approaches for School-based Malaria Control
• Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Midazolam, Repaglinide, Dextromethorphan, Metformin, Rosuvastatin and Dolutegravir
• Primaquine Double Dose for Radical Cure of Plasmodium Vivax in Colombia
• A Study Of Zy-19489 Administered Via Oral Route To Investigate The Safety, Tolerability And Pharmacokinetics In Healthy Adult Human Subjects
• MMV533 Plasmodium Falciparum Volunteer Infection Study
• Efficacy and Safety of Pyronaridine-Artesunate Versus Artemether-Lumefantrine
• Effectiveness of Seasonal Malaria Chemoprevention in Nampula Province, Mozambique: Type Two Hybrid Implementation Study
• Study to Compare Feasibility of 1-step Injectable Artesunate vs. Conventional 2-step Injectable Artesunate
• Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Itraconazole
• Efficacy of Antimalarial Drugs Used for the Treatment of Uncomplicated Malaria, Plasmodium Falciparum, at the Agadez, Gaya and Tessaoua Sentinel Sites
• Therapeutic Efficacy Study of AL and DP in Western Kenya
• Study to Evaluate Primaquine for Radical Cure of Uncomplicated Plasmodium Vivax Malaria in Children
• VRC 614: A Phase 1, Dose Escalation, Open-Label Clinical Trial With Experimental Controlled Human Malaria Infections (CHMI) to Evaluate Safety and Protective Efficacy of an Anti-Malaria Human Monoclonal Antibody, VRC-MALMAB0114-00-AB (L9LS), in Heal
• Modifying Immunity in Children With DihydROartemisinin-Piperaquine (MIC-DroP)
• Broad One Health Endectocide-based Malaria Intervention in Africa (BOHEMIA)
• Safety and Efficacy of Maytenus Senegalensis for the Treatment of Uncomplicated Malaria
• Effectiveness and Safety of Artemether + Lumefantrine and Dihydroartemisinin + Piperaquine for the Treatment of Uncomplicated Malaria in Guinea-Bissau
• Assessment of the Therapeutic Efficacy and Tolerability of the Artesunate/Amodiaquina Combination and Artemether/Lumefantrine Combination, Treatment of Uncomplicated P. Falciparum Malaria in the Department of Chocó (Colombia)
• Mass Drug Administration of Dihydroartemisinin-piperaquine + Single Low-dose Primaquine to Accelerate Toward Elimination Activities
• Adjunctive Ivermectin Mass Drug Administration for Malaria Control
• Dihydroartemisinin-Piperaquine or Sulphadoxine-Pyrimethamine for the Chemoprevention of Malaria in Sickle Cell Anaemia
• Efficacy and Safety of Artesunate-amodiaquine and Artemether-lumefantrine for the Treatment of Malaria in Cameroon
• Boosting the Impact of SMC Through Simultaneous Screening and Treatment of Roommates
• Comparison of ISTp- PYRAMAX-US-RDT to IPTp-SP to Prevent Malaria in Pregnant Women in DRC (ULTRAPYRAPREG)
• Evaluation of Three Artemisinin-based Combinations for the Treatment of Uncomplicated Malaria in Childreen in Burkina Faso (CHIMIO2)
• Malaria Therapeutic Efficacy Study, Rwanda
• Malaria Therapeutic Efficacy Study (TES) Kenya
• Efficacy of SJ733 in Adults With Uncomplicated Plasmodium Falciparum or Vivax Malaria
• Optimizing Malaria Treatment for HIV-Malaria Co-infected Individuals
• Southeast Asia Dose Optimization of Tafenoquine
• Malaria as a Risk Factor for COVID-19 in Western Kenya and Burkina Faso
• To Evaluate Efficacy, Safety, Tolerability and PK of Intravenous Cipargamin in Participants With Severe Plasmodium Falciparum Malaria
• Household-level Impact of IPT of Malaria in Schoolchildren
• Safety and Efficacy of Recommended Antimalarial in the Democratic Republic of the Congo
• Effectiveness and Safety of Artesunate-Amodiaquine and Artemether-Lumefantrine for the Treatment of Malaria in Yaounde
• Efficacy, Safety and Tolerability of KAF156 in Combination With Lumefantrine Solid Dispersion Formulation (LUM-SDF) in Pediatric Population With Uncomplicated Plasmodium Falciparum Malaria
• Assess Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Profile of Ruxolitinib With Artemether-lumefantrine
• Effectiveness of Novel Approaches to Radical Cure With Tafenoquine and Primaquine
• In Vivo Efficacy of Artemether-lumefantrine and Amodiaquine-artesunate in Mozambican Children (MEFI_III)
• Safety and Efficacy of Pyronaridine Artesunate Versus Chloroquine in Children and Adult Patients With Acute Plasmodium Vivax Malaria
• Optimal Chemopreventive Regimens to Prevent Malaria and Improve Birth Outcomes in Uganda
• Clinical Study of Meplazumab to Treat With Malaria
• A Phase 1 Study to Assess the Safety, Tolerability, and Pharmacokinetic Profile of a Single Doses of MMV533.
• Study to Assess Safety, Tolerability and Phamacokinetics of KAE609 Administered Intravenously in Healthy Subjects
• Seasonal Malaria Vaccination (RTS,S/AS01) and Seasonal Malaria Chemoprevention (SP/AQ) Extension Study
• Gut and Azithromycin Mechanisms in Infants and Children II
• Study in Blood Stage Malaria Infection After DVI of Cryopreserved P. Falciparum (NF54 Strain) Sporozoites
• Determining the Impact of Scaling up Mass Testing, Treatment and Tracking on Malaria Prevalence in Ghana
• Pharmacokinetics, Safety, Tolerability and Efficacy of a New Artemether-lumefantrine Dispersible Tablet in Infants and Neonates <5 kg Body Weight With Acute Uncomplicated Plasmodium Falciparum Malaria
• A Trial For The Study of Falciparum Malaria Protein 014 Administered Via Intramuscular Injection in Healthy Adults
• Nitrite Infusion in Children With Malaria
• Controlled Human Malaria Infection Transmission Model - Phase A
• A Trial For The Study of Falciparum Malaria Protein 013 Administered Via Intramuscular Injection in Healthy Adults
• Effect of Artemisinin-based Combination Therapies on Schistosomiasis on Malaria Co-infection
• Effect of Paracetamol on Kidney Function in Severe Malaria
• Chemoprophylactic Activity of M5717 in PfSPZ Challenge Model
• Evaluation of the Implementation and Effectiveness of Intermittent Preventive Treatment for Malaria Using Dihydroartemisinin-piperaquine on Reducing Malaria Burden in School Aged Children in Tanzania
• Assessment of a Combined Strategy of SMC + Nutrients Supplementation to Tackle Malaria and Malnutrition
• Biomarkers of P. Vivax Relapse
• TES Artemether-lumefantrine for Pf and Chloroquine (CQ) for Pv
• Trial to Evaluate CIS43LS in Healthy Adults
• A Clinical Trial to Evaluate Plasmodium Falciparum 7G8 and NF54 Challenge Strains (PfSPZ) in a Head-to-head Comparative Study - (ECG-CHMI)
• The ASPIRE Trial - Aiming for Safe Pregnancies by Reducing Malaria and Infections of the Reproductive Tract
• Acceptability and Feasibility in the Context of the IMPROVE Trial in Kenya
• Improving PRegnancy Outcomes With PReVEntive Therapy in Africa-2 (IMPROVE-2)
• Seasonal Malaria Chemoprevention With Dihydroartemisin Piperaquin vs. Sulfadoxine-pyrimethamin+Amodiaquin
• Additional Screening With Sensitives RDTs and Malaria
• Malaria High-Risk Populations in Namibia
• Mass Screening and Treatment for Reduction of Falciparum Malaria
• Short Course Radical Cure of P. Vivax Malaria in Nepal
• Safety and Causal Prophylactic Efficacy of KAF156 in a Controlled Human Malaria Challenge Model
• Absolute BA and OZ439 PK Effect of Different OZ439 Dose Volumes and Cobicistat Co-administration Study
• Study to Assess Efficacy of Artemether-lumefantrine Prophylaxis Against Forest Malaria in Cambodia (PAL_Cambodia)
• A Study to Assess the Safety and Efficacy of 5-aminolevulinic Acid Hydrochloride (5-ALA HCl) and Sodium Ferrous Citrate (SFC) Added on Artemisinin-based Combination Therapy (ACT) in Adult Patients With Uncomplicated Malaria
• Pharmacokinetics and Pharmacodynamics of the Gametocytocidal and Post-treatment Chemoprotective Effects of Antimalarials
• Determine the Tolerability and Safety of Atovaquone-proguanil (ATV-PG) Co-administered With Amodiaquine (AQ)
• Repeat Ivermectin Mass Drug Administrations for MALaria Control II
• Sanaria PfSPZ Challenge With Pyrimethamine or Chloroquine Chemoprophylaxis Vaccination (PfSPZ-CVac Approach): A Randomized Double Blind Placebo Controlled Phase I/II Trial to Determine Safety and Protective Efficacy Against Natural Plasmodium Falcip
• Azithromycin (AZ) and Sulphadoxine-pyrimethamine (SP) for Malaria Prevention in Pregnant Women (IPT-AZ/IPT-SP)
• A Trial to Compare the Efficacy, Safety and Tolerability of Combinations of 3 Anti-malarial Drugs Against Combinations of 2 Anti-malarial Drugs (Asia)
• A Trial to Compare the Efficacy, Safety and Tolerability of Combinations of 3 Anti-malarial Drugs Against Combina-tions of 2 Anti-malarial Drugs.
• Reducing the Risk of P. Vivax After Falciparum Infections in Co-endemic Areas
• Pyramax in Asymptomatic Carriers of P. Falciparum Monoinfections
• Safety and Efficacy of NF135 CPS Immunization
• Efficacy and Safety of Artesunate + Amodiaquine With SLD of Primaquine for Treatment of Falciparum Malaria in Zanzibar
• Efficacy of Artesunate + Amodiaquine Versus Artemether-lumefantrine for Falciparum Malaria in Zanzibar, 2005
• Tolerability and Efficacy of Artemether-Lumefantrine Versus Artesunate + Amodiaquine in Zanzibar
• Drug Combinations of Atovaquone-Proguanil (AP) With ACT
• Safety, Tolerability and Chemoprotective Activity of P218 in PfSPZ Challenge Model
• Improving Maternal heAlth by Reducing Malaria in African HIV Women
• Study to Investigate the Clinical and Parasiticidal Activity and Pharmacokinetics of Different Doses of Artefenomel and Ferroquine in Patients With Uncomplicated Plasmodium Falciparum Malaria
• Effectiveness and Safety of Intermittent Preventive Treatment for Malaria Using Either Dihydroartemisinin-piperaquine or Artesunate-amodiaquine in Reducing Malaria Related Morbidities and Improving Cognitive Ability in School-aged Children in Tanzan
• Efficacy of 3 Regimens of Chloroquine and Primaquine for Treatment of P. Vivax Malaria, Cruzeiro do Sul, Acre, Brazil
• Monthly Versus Two Doses of Ante-Natal Intermittent Preventive Treatment With Sulphadoxine-Pyrimethamine
• Mass Drug Administration of Ivermectin and Dihydroartemisinin-piperaquine as an Additional Intervention for Malaria Elimination
• Safety, Tolerability and Antimalarial Activity of Single Doses of OZ439 and PQP
• Safety and Efficacy of Different Regimens of Primaquine on Vivax Malaria Treatment in G6PD Deficient Patients
• Safety, Immunogenicity, and Protective Efficacy of Two Regimens of Radiation Attenuated Plasmodium Falciparum NF54 Sporozoites (PfSPZ Vaccine) During Natural Transmission Season in Healthy African Adults in Mali
• Safety, Tolerability, Immunogenicity and Protective Efficacy of PfSPZ Vaccine and PfSPZ-CVac in Indonesian Adults Against Naturally-Transmitted Malaria
• Safety and Pharmacokinetics Study of DM1157 to Treat Malaria
• Controlled Human Malaria Infection Model for Evaluation of Transmission-blocking Interventions - Study 2
• Extended Duration Artemether-lumefantrine Treatment for Malaria in Children
• Comparison of Arterolane-piperaquine Versus Arterolane-piperaquine+Mefloquine Versus Artemether-lumefantrine in Kenyan Children
• Study Assessing Pharmacokinetics and Bioavailability of Three Novel Triazine Compounds
• Efficacy and Safety of ASAQ and PD for the Treatment of Uncomplicated Falciparum Malaria in Mainland Tanzania
• A Novel Regimen to Prevent Malaria and STI in Pregnant Women With HIV
• Aggressive Antipyretics for Fever Reduction in CNS Malaria
• Study to Compare the Triple ACT AL+AQ With the ACT AL in Cambodia and Vietnam
• Single Low-dose Primaquine Efficacy and Safety.
• Safety of KAE609 in Adults With Uncomplicated Plasmodium Falciparum Malaria.
• Treating Brain Swelling in Pediatric Cerebral Malaria
• Chloroquine (CQ) and Azithromycin (AZ) Combination for Malaria Prophylaxis
• DHA-PQP vs Chloroquine and Primaquine for Radical Cure of Vivax Malaria in Brazil
• Improving PRegnancy Outcomes With Intermittent preVEntive Treatment in Africa
• Cohort Event Monitoring Study of Pyramax®
• Dried Leaf Artemisia (DLA) Compared to Artemisinin Combination Therapy (ACT) vs Malaria
• Chemoprotective Activity of MMV390048 in PfSPZ Challenge Model
• Enhancing Preventive Therapy of Malaria In Children With Sickle Cell Anemia in East Africa (EPiTOMISE)
• Efficacy and Safety of KAF156 in Combination With LUM-SDF in Adults and Children With Uncomplicated Plasmodium Falciparum Malaria
• Seasonal Malaria Vaccination (RTS,S/AS01) and Seasonal Malaria Chemoprevention (SP/AQ)
• Optimizing Hydroxyurea Therapy in Children With SCA In Malaria Endemic Areas
• Dose Escalation PfSPZ-CVac
• Effect of Paracetamol on Renal Function in Plasmodium Knowlesi Malaria
• Efficacy and Safety of IPTp-DP Versus IPTp-SP in Malawi
• Safety and Efficacy of Sanaria's PfSPZ-CVac in Malian Adults
• Evaluation of Community-based Mass Screening and Treatment for Malaria in Western Kenya
• Physiologically-based Pharmacokinetic Modeling of Ivermectin in Healthy Human Volunteers
• Safety and Immunogenicity of Pfs25M-EPA/AS01 and Pfs230D1M-EPA/AS01 Vaccines, Transmission Blocking Vaccines Against Plasmodium Falciparum, at Full and Fractional Dosing in Adults in Mali
• Efficacy and Safety of Artemisinin-based Combination Treatments in the Democratic Republic of the Congo
• Mass Drug Administrations of DHA-PQP to Accelerate Towards Malaria Elimination in Magude District, Southern Mozambique
• Cardiac Safety of Dihydroartemisinin-Piperaquine Amongst Pregnant Women in Tanzania
• A Safety and Efficacy Study of R21 +/- ChAd63/MVA ME-TRAP
• Metabolism and Pharmacokinetics of Primaquine Enantiomers in Human Volunteers, Study 1
• A FIH Study to Investigate the Safety, Tolerability and PK of P218
• MMV390048 POC in Patients With P. Vivax and P. Falciparum Malaria
• G6PD Assessment Before Primaquine for Radical Treatment of Vivax Malaria
• SJ733 Induced Blood Stage Malaria Challenge Study
• Safety and Protective Efficacy of IV Immunization With Cryopreserved PfSPZ Under A/P Chemoprophylaxis
• Methylene Blue Against Falciparum Malaria in Burkina Faso
• Controlled Human Malaria Infection Model for Evaluation of Transmission-Blocking Interventions - Study 1
• Phase 2 Efficacy Study of Primaquine and Methylene Blue
• P.Vivax Treatment Trial
• Efficacy and Safety Study of Tafenoquine (TQ) Co-administered With Dihydroartemisinin-piperaquine (DHA-PQP) for the Radical Cure of Plasmodium Vivax (P. Vivax) Malaria
• Prevention of Malaria in HIV-uninfected Pregnant Women and Infants
• A Trial on Supervised Primaquine Use in Ethiopia
• Molecular Surveillance of Artemisinin Resistance Malaria in Myanmar
• Prevention of Malaria With Dihydroartemisinine + Piperaquine for Forest Rangers
• A Randomized Controlled Trial on Malaria Primaquine Treatment in Timika, Indonesia (TRIPI)
• MMV390048 and Its Antimalarial Activity Against Plasmodium Falciparum in Healthy Adult Subjects, Part B
• Safety, Tolerability and Pharmacokinetic Profile of Ascending Oral Doses of MMV390048, Part A
• PfSPZ Challenge in Healthy Malaria-Naïve Adults in the United States
• The Impact of Sulphadoxine-Pyrimethamine Use At Scale on Newborn Outcomes in Nigeria
• A Study to Assess the Effects of Dissolution Profile on the Pharmacokinetics of Single Oral Doses of Tafenoquine Tablets and Tafenoquine Stable Isotope Labelled Solution
• Lumefantrine in Venous Plasma Versus Dried Capillary Blood Spot
• Efficacy of Artesunate-amodiaquine and Artemether-lumefantrine for Uncomplicated Malaria in South Kivu, DR Congo
• A Microdose Study in Healthy Subjects to Describe Intravenous Pharmacokinetics of GSK3191607
• Delivery of Malaria Chemoprevention in the Post-discharge Management of Children With Severe Anaemia in Malawi
• Effectiveness of Mass Drug Administration for Reducing Seasonal Malaria Transmission in Zanzibar
• Evaluating the Role of Chloroquine for Malaria Elimination
• Methylene Blue Against Vivax Malaria in Ethiopia
• Rosiglitazone Adjunctive Therapy for Severe Malaria in Children
• Efficacy of Chloroquine (CQ) Alone Compared to Concomitant CQ and Primaquine for Plasmodium Vivax Infection
• Post-discharge Malaria Chemoprevention(PMC) Study
• Safety and Immunogenicity of Sanaria's Irradiated Sporozoite Vaccine (PfSPZ Vaccine) in Malaria-Experienced Adults in Burkina Faso
• First-in-Human Study of an Oral Plasmodium Falciparum Plasma Membrane Protein Inhibitor
• Assessment of Any Potential Retinal Effects of Tafenoquine (TQ)
• Community-led Responses for Elimination: Controlled Trial of Reactive Case Detection Versus Reactive Drug Administration
• Evaluation of the Safety of Primaquine in Combination With Dihydroartemisinin-piperaquine in G6PD Deficient Males in The Gambia
• Malaria Elimination Pilot Study in Military Forces in Cambodia
• Artemisinin Resistance In Malaria Treated With IV Artesunate
• In Vivo Efficacy of Artemether-Lumefantrine and Artesunate-Amodiaquine for Uncomplicated P. Falciparum Malaria
• Safety, Immunogenicity, and Protective Efficacy of Radiation Attenuated Plasmodium Falciparum NF54 Sporozoites in Healthy African Adults in Mali
• Effect of Imatinib on Suppression of Malaria Parasites in Patients With Uncomplicated Plasmodium Falciparum Malaria
• Efficacy, Safety, and Tolerability of Dihydroartemisinin-piperaquine + Mefloquine Compared to Dihydroartemisinin-piperaquine or Artesunate-mefloquine in Patients With Uncomplicated Falciparum Malaria in Cambodia
• Evaluating the Efficacy of Chloroquine for the Treatment of Plasmodium Vivax Infections in Central Vietnam
• Cardiac Safety of Repeated Doses of Dihydroartemisinin-Piperaquine for the Use in Mass Treatment Campaigns
• P. Falciparum Resistance to Artemisinin in Vietnam
• Artemether-lumefantrine for Treatment of P. Falciparum Malaria in Brazil
• A Study to Assess Current Standard Malaria Treatment Guidelines in the Republic of the Sudan
• In-vivo Efficacy and Safety of Artemether/Lumefantrine Vs Dihydroartemisinin-piperaquine for Treatment of Uncomplicated Malaria and Assessment of Parasite Genetic Factors Associated With Parasite Clearance or Treatment Failure
• A Safety, Tolerability, Pharmacokinetic and Efficacy Study of Azithromycin Plus Piperaquine as Presumptive Treatment in Pregnant PNG Women
• A Study to Characterise the Antimalarial and Transmission Blocking Activity of a Single Dose of DSM265 or OZ439 in Healthy Subjects With Induced Blood Stage Plasmodium Falciparum or Plasmodium Vivax Infection
• A Trial of the Efficacy of Artesunate and Three Quinine Regimens in the Treatment of Severe Malaria in Children at the Ebolowa Regional Hospital - Cameroon
• A Pharmacokinetics, Safety and Efficacy Study of Tafenoquine (TQ) in Pediatric Subjects With Plasmodium Vivax (P. Vivax) Malaria
• DSM265 Prophylaxis of Plasmodium Falciparum Malaria
• A Study to Evaluate the Pharmacokinetics of Oral Formulations of MMV390048 Administered Fasted to Healthy Volunteers
• Effectiveness of KAE609 in Reducing Asexual & Sexual Blood-stage P.Falciparum Infection & Infectivity to Mosquitos
• Determining a Tolerable Dose of Primaquine in G6PD-deficient Persons Without Malaria in Mali
• The Effectiveness of Non-Pyrethroid Insecticide-Treated Durable Wall Liners as a Method for Malaria Control in Endemic Rural Tanzania
• Relapses in Plasmodium Ovale and Efficacy of Artemether-lumefantrine for Mixed Species and Non-falciparum Malaria
• A Comparative Study of Azithromycin and S-P as Prophylaxis in Pregnant HIV+ Patients
• A Comparative Study of Mefloquine and S-P as Prophylaxis Against Malaria in Pregnant HIV + Patients
• Efficacy and Safety of High-dose Ivermectin for Reducing Malaria Transmission: A Dose Finding Study
• Sanaria PfSPZ Challenge With Pyrimethamine Chemoprophylaxis (PfSPZ-CVac Approach): Phase 1 Trial to Determine Safety and Protective Efficacy of Sanaria PfSPZ Challenge With Concurrent Pyrimethamine Treatment That Inhibits Development of Asexual B...
• Repeat Ivermectin Mass Drug Administrations for Control of Malaria: a Pilot Safety and Efficacy Study
• To Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of a Single Dose Regimen of Ferroquine and Artefenomel in Adults and Children With Uncomplicated Plasmodium Falciparum Malaria
• Bio-availability of Rectal Artesunate in Children With Severe Falciparum Malaria
• Evaluation of Weekly Tafenoquine
• A Randomized, Double-blind, Placebo-controlled Evaluation of Increasing Doses of Weekly Tafenoquine for Chemosuppression of Plasmodium Falciparum
• Arterolane-PQP Versus DHA-PQP in Uncomplicated Falciparum Malaria in Eastern Myanmar
• Effectiveness of OZ439 Against Early Plasmodium Falciparum Blood Stage Infection in Healthy Volunteers
• A Study by the Tracking Resistance to Artemisinin Collaboration (TRAC)
• DSM265 Chemoprophylaxis of Plasmodium Falciparum Malaria
• Safety and Tolerability of Low Dose Primaquine
• Effectiveness of OZ439 as a Gametocytocidal and Transmission Blocking Agent
• Experimental Falciparum Transmission to Anopheles
• Pyronaridine-artesunate and Artemether-lumefantrine for the Treatment of Paediatric Malaria
• Effectiveness of Malaria Treatment in Mexico
• Efficacy and Safety of Pyronaridine-artesunate for the Treatment in Uncomplicated Falciparum Malaria
• A Study to Assess Safety of Current Standard Malaria Treatment and an Assessment of G6PD Status in South-east Bangladesh
• A Phase Ib Induced Malaria Infection Study With the Combination of OZ439 and DSM265
• Bioavailability Study of Oral OZ439 Prototype Granule Formulations Administered With Piperaquine Phosphate (PQP) Tablets
• Investigation of Short Course, High Dose Primaquine Treatment for Liver Stages of Plasmodium Vivax Infection
• Efficacy and Safety of Dihydroartemisinin-piperaquine (DHP) for the Treatment of Uncomplicated Malaria
• Artemether-lumefantrine vs Chloroquine for Uncomplicated P. Vivax Malaria in Malaysia
• Study of the Safety and Immunogenicity of Pfs230D1M-EPA/Alhydrogel and Pfs25M-EPA/Alhydrogel , a Transmission Blocking Vaccine Against Plasmodium Falciparum Malaria, in Adults in the U.S. and Mali
• Mass Drug Administration With Dihydroartemisinin + Piperaquine for Reducing Malaria in Southern Zambia
• Artemisinin-based Combination Therapy for Treatment of Plasmodium Falciparum Malaria in North Sumatera, Indonesia
• Evaluation of Reactive Focal Mass Drug Administration for Malaria Elimination in Swaziland
• The ASAP Study - Therapeutic Efficacy of Atovaquone-proguanil vs. Artesunate-atovaquone-proguanil in Cambodia
• Reducing the Burden of Malaria in HIV-Infected Pregnant Women and Their HIV-Exposed Children (PROMOTE-BC2)
• MMV390048 Against Early Plasmodium Falciparum Blood Stage Infection in Healthy Participants
• Dihydroartemisinin-piperaquine With Low Dose Primaquine to Reduce Malaria Transmission
• Dolutegravir Interactions With Artemisinin-based Combination Therapies
• Phase I Study of Ascending Doses of MMV390048 in Healthy Adult Volunteers
• Effect of ACT-451840 Against Early Plasmodium Falciparum Blood Stage Infection in Healthy Subjects
• Study to Assess the Incidence of Hemolysis, Safety, and Efficacy of Tafenoquine (SB-252263, WR238605) Versus Primaquine in Subjects With Plasmodium Vivax Malaria
• School-based Programme of Malaria Diagnosis and Treatment in Southern Malawi
• A Trial of Seasonal Malaria Chemoprevention Plus Azithromycin in African Children
• Introduction of Eurartesim® in Burkina Faso, Mozambique, Ghana and Tanzania
• Evaluation of Fosmidomycin and Piperaquine in the Treatment of Acute Falciparum Malaria
• A Study to Evaluate the Pharmacokinetics of a Single Dose of Tafenoquine Co-administered With Either Artemether + Lumefantrine or Dihydroartemisinin + Piperaquine Tetraphosphate
• Safety of Primaquine + Artemether-lumefantrine in G6PD Deficient Males With an Asymptomatic Malaria Infection (SAFEPRIM)
• In Vivo Efficacy of Artemether-lumefantrine and Amodiaquine-artesunate in Mozambican Children
• Reducing the Burden of Malaria in HIV-uninfected Pregnant Women and Infants
• Effect of Liver and Blood-stage Treatment on Subsequent Plasmodium Reinfection and Morbidity
• DSM265 Phase IIa Investigation Treating Plasmodium Falciparum or Vivax
• Assessment of Plasmodium Vivax Chloroquine Resistance in Cambodia:
• Eurartesim® in Patients With Imported Uncomplicated Plasmodium Vivax Malaria
• Chemoprophylaxis and Plasmodium Falciparum NF54 Sporozoite Immunization Challenged by Heterologous Infection
• Parenteral Artesunate Compared to Quinine as a Cause of Late Anaemia in African Children With Malaria
• Efficacy and Safety of a Single Low-dose Primaquine for the Clearance of Gametocytes
• Efficacy of Artemether/Lumefantrine for the Treatment of Uncomplicated Malaria.
• Bioavailability Study of Oral OZ439 Prototype Formulations Administered With Piperaquine Phosphate (PQP)
• Phase II Efficacy Study of Artefenomel & Piperaquine in Adults & Children With P. Falciparum Malaria.
• Target Antigens Induced by Plasmodium Falciparum Sporozoite Immunization Under Chemoprophylaxis
• Harmonized AS/MQ Efficacy Study - Thailand
• Plasmodium Vivax Efficacy Trial in Cruzeiro do Sul, Acre, Brazil
• Optimising Operational Use of Artemether-lumefantrine Comparing 3 Day Versus 5 Day
• School-Based Treatment With ACT to Reduce Transmission
• Malaria in Early Life Study
• P. Knowlesi Trial of Artemether-lumefantrine vs Chloroquine
• A Pharmacokinetic/Pharmacodynamic Study of Eurartesim Dispersible Formulation in Infants With P.Falciparum Malaria
• Study of Safety and Effectiveness of Intravenous Immunization With PfSPZ Vaccine in Healthy African Adults
• A Safety and Feasibility Study of Enteral LVT vs. Standard of Care for Seizure Control in Pediatric CM
• In Vivo and In Vitro Efficacy of Artemisinin Combination Therapy
• Novel Use Of Hydroxyurea in an African Region With Malaria
• Adherence to Antimalarial Drugs in Sierra Leone
• Open Label Pharmacokinetic Study of OZ439 and Piperaquine on Administration of OZ439+TPGS Granules for Oral Suspension Alone or With Either Piperaquine Phosphate Tablets or Granules for Oral Solution in Healthy Volunteers
• Evaluation of Oral Activated Charcoal on Antimalarial Drug's Ability to Kill Parasites in Malian Children With Malaria
• Treatment Efficacy and Malaria TRANSmission After Artemisinin Combination Therapy 2 (TRANSACT2)
• Low Dose Primaquine for Clearance of Gametocytes
• Safety, Tolerability, Pharmacokinetics and Efficacy of ARCO
• Comparison of Two Regimens of Artemether-lumefantrine for the Treatment of Malaria in Pregnancy
• The Optimal Timing Of Primaquine To Prevent Malaria Transmission After Artemisinin-Combination Therapy
• Evaluation of the Efficacy of Artemisinin Combination Therapy in Kenya
• Antimalarial Drug Susceptibility and Molecular Characterization of Plasmodium Vivax Isolates in Vietnam
• Surveillance and Treatment With Dihydroartemisinin-piperaquine Plus Primaquine
• Targeted Chemo-elimination (TCE) of Malaria
• Relative Bioavailability of Pyronaridine-artesunate in Tablet and Granule Formulations, in Healthy Volunteers
• A Study to Assess Efficacy, Safety of KAE609 in Adult Patients With Acute Malaria Mono-infection
• Single Oral Dose Study of Atovaquone/Proguanil Hydrochloride Combination Tablets and Atovaquone Suspension
• Healthy Volunteer Study of the Pharmacokinetics of Oral Piperaquine With OZ439 + TPGS Formulation in the Fasted State
• Antimalarial Drug Resistance With Assessment of Transmission Blocking Activity
• Artemisinin-Based Antimalarial Combinations and Clinical Response in Cameroon
• Primaquine's Gametocytocidal Efficacy in Malaria Asymptomatic Carriers
• Safety and Efficacy of Primaquine for P. Vivax
• A Study to Find the Minimum Inhibitory Concentration of KAE609 in Adult Male Patients With P. Falciparum Monoinfection
• IMPROV (Improving the Radical Cure of Vivax Malaria)
• Pharmacokinetic Study of Multi-dose Chloroquine
• Intravenous Artesunate and Malaria
• Parasitic Clearance and Recurrence Rates Among Patients With Vivax Malaria
• Immunization With Plasmodium Falciparum Sporozoites Under Chloroquine or Chloroquine/Azithromycin Prophylaxis
• Primaquine Pharmacokinetics in Lactating Women and Their Infants
• Plasmodium Falciparum Artemisinin Resistance Vietnam
• Efficacy of Three ACTs for the Treatment of Falciparum Malaria in Maradi Niger
• Efficacy, Safety, Tolerability and Pharmacokinetics of KAF156 in Adult Patients With Acute, Uncomplicated Plasmodium Falciparum or Vivax Malaria Mono-infection
• Efficacy of Antifolates Against Malaria in HIV-infected Pregnant Women and the Emergence of Induced Resistance in Plasmodium Falciparum
• Phase2a Primaquine Dose Escalation Study
• Pharmacology of Antimalarial Therapy With or Without Antiretroviral Therapy
• Safety and Efficacy of Chloroquine and Primaquine for Vivax Malaria in Bhutan
• OZ439 PhIIa Study in Plasmodium Falciparum: Extended Observation
• A Dose-escalation Study to Investigate Safety and Toleration of OZ439
• P. Knowlesi Trial of Artesunate-mefloquine Versus Chloroquine
• SPK Study in Afghanistan
• Improving Anti-malarial Treatment Options in Guinea-Bissau - Part A
• ANC & Malaria Diagnostic in Pregnancy
• Amodiaquine-Artesunate & Artemether-Lumefantrine Efficacy in Burkina Faso
• Ethiopia Antimalarial in Vivo Efficacy Study 2012
• Efficacy of Intermittent Screening and Treatment or Intermittent Preventive Treatment (IPT) With Dihydroartemisinin-Piperaquine, Versus IPT With Sulfadoxine-Pyrimethamine for the Control of Malaria in Pregnancy in Kenya
• Comparison of Two Antimalarial Drugs Regimens in Patient With Plasmodium Vivax Malaria in Thailand
• Re-exposure of Human Volunteers to a Heterologous Strain of P. Falciparum Sporozoites
• Enteral Levetiracetam For Seizure Control In Pediatric Cerebral Malaria
• Efficacy of Artesunate-Mefloquine Combination Therapy in Trat Province, Thailand
• Impact of Repeated Anthelmintic Treatment on the Risk of Malaria in Kenyan School Children
• Seasonal Malaria Chemoprevention Versus Home Management of Malaria in Children Under 5 Years in Ghana
• Phase 1b Malaria Clinical Trial Using Argemone Mexicana in Healthy Adults in Mali
• Paracetamol Effect on Oxidative Stress and Renal Function in Severe Malaria
• Compare the Effectiveness Between Existing Treatment and New Treatment
• Artemether/Lumefantrine and Vivax Malaria
• Malaria Prevention Cambodia
• Efficacy, Safety and Pharmacokinetics of Artemether-lumefantrine Dispersible Tablet in the Treatment of Malaria in Infants < 5 kg
• Safety, Tolerability & Pharmacokinetics (PK) of Co-administered Single Doses of OZ439 and Mefloquine (MQ) in Healthy Volunteers
• Studies of a Candidate Aminoquinoline Antimalarial (AQ-13)
• Trial of Artemether-Lumefantrine Alone and in Combination With Ivermectin to Reduce Post-Treatment Malaria Transmission
• Phase II Dose-ranging Study of Pyronaridine/Artesunate in Adults Patients With Plasmodium Falciparum Malaria
• Reducing the Burden of Malaria by Targeting Hotspots of Malaria Transmission
• Efficacy Study of Amodiaquine-Artesunate and Artemether-Lumefantrine for the Treatment of Uncomplicated Malaria
• Chloroquine Population Pharmacokinetics in Pre and Post-partum Women
• Sanaria™ PfSPZ Challenge Vaccine
• Efficacy, Safety, Tolerability and Pharmacokinetics of KAE609 in Adult Patients With Acute, Uncomplicated Plasmodium Falciparum or Vivax Malaria Mono-infection
• Drug Interaction Study of Pyronaridine-artesunate and Metoprolol and Pyronaridine-artesunate Re-dosing Study in Healthy Volunteers
• Malaria Challenge in Healthy Volunteers
• Evaluation of Fosmidomycin and Clindamycin in the Treatment of Acute Uncomplicated P.Falciparum Malaria in Children
• Fosmidomycin and Azithromycin for Acute Uncomplicated Plasmodium Falciparum Malaria (P. Malaria) in Adults
• Artemisinin-based Combination Therapy-Intermittent Preventive Treatment (ACT-IPT) Trial Among Schoolchildren in Kassena-Nankana, Ghana
• Intermittent Parasite Clearance (IPC) in Schools: Impact on Malaria, Anaemia and Cognition
• Trial of Malaria Seasonal IPTc Combined With Community Case Management
• Anti-parasitic Activity and Safety Assessment of SAR97276A in Children With Uncomplicated Malaria
• Chloroquine for Malaria in Pregnancy
• Sevuparin/DF02 as an Adjunctive Therapy in Subjects Affected With Uncomplicated Falciparum Malaria
• Immunization With Plasmodium Falciparum Sporozoites Under Chloroquine Versus Mefloquine Prophylaxis
• Efficacy and Safety of Artesunate-amodiaquine-methylene for Malaria Treatment in Children
• Dihydroartemisinin-piperaquine and Primaquine for Uncomplicated Plasmodium Falciparum Cases
• Impact of Dihydroartemisinin-piperaquine Plus Primaquine on Malaria Transmission in Lampung Province, Sumatra
• Evaluation of the Efficacy and Safety of Inhaled Nitric Oxide as Adjunctive Treatment for Cerebral Malaria in Children
• Human Mass Balance Study of Pyronaridine
• Efficacy and Tolerability of Artesunate Amodiaquine Versus Chloroquine in the Treatment of Uncomplicated Plasmodium Vivax Malaria
• Ph 2B/3 Tafenoquine (TFQ) Study in Prevention of Vivax Relapse
• Impact of Artemisinin-based Combination Therapy and Quinine on Treatment Failure and Resistance in Uncomplicated Malaria
• Azithromycin Combination Therapy for the Treatment of Severe Malaria
• Evaluation of the Gametocytocidal Efficacy and Safety of Primaquine in Uncomplicated Falciparum Malaria in Uganda
• Evaluation of Fosmidomycin and Clindamycin in the Treatment of Acute Uncomplicated Plasmodium Falciparum Malaria
• Tracking Resistance to Artemisinin (TRAC)
• Pharmacokinetics of Sulfadoxine-pyrimethamine Plus Amodiaquine for Intermittent Preventive Treatment in Children (IPTc)
• Efficacy of Artemether-lumefantrine, Artesunate-amodiaquine and Dihydroartemisinin-piperaquine for the Treatment of Uncomplicated Plasmodium Falciparum Malaria in Malawi
• Intermittent Preventive Treatment for Malaria in Patient With Sickle Cell Disease
• Study to Evaluate the Efficacy and Safety of Tafenoquine for the Treatment of Plasmodium Vivax in Adults
• Study of ACTs Plus Primaquine for Uncomplicated Plasmodium Vivax Malaria
• Malaria Active Epidemiology and Treatment Study
• Superiority of ArTiMist Versus Quinine in Children With Severe Malaria
• A Community Setting Study of Malaria After Systematic Treatment of Symptomatic Carriers of P. Falciparum With COA566 (Coartem®)
• Inhaled Nitric Oxide for the Adjunctive Therapy of Severe Malaria: a Randomized Controlled Trial
• Experimental Human Malaria Infection After Immunization With Plasmodium Falciparum Sporozoites Under Chloroquine Prophylaxis
• School Based Malaria Control in Ugandan Schoolchildren
• Efficacy,Safety and Tolerability of Dihydroartemisinin-Piperaquine for Uncomplicated Malaria in Pregnancy in Ghana
• Immunization With Different Doses of Plasmodium Falciparum Sporozoites Under Chloroquine Prophylaxis
• Efficacy, Tolerability, PK of OZ439 in Adults With Acute, Uncomplicated P.Falciparum or Vivax Malaria Mono-infection
• Amodiaquine+Artesunate for Uncomplicated Malaria Treatment
• G6PD (Glucose-6-phosphate Dehydrogenase) Study to Evaluate Hemolysis Potential of TFQ (Tafenoquine)
• Efficacy of Artesunate-amodiaquine (AS-AQ) in Children With Malaria and Severe Acute Malnutrition, Madaoua, Niger 2010
• Introducing Rapid Diagnostic Tests Into the Private Health Sector
• Have Malaria Infections in Kenya Become Less Responsive to Artemisinin Treatment?
• Sulphadoxine-Pyrimethamine for Intermittent Preventive Treatment of Malaria in Pregnancy in Uganda
• Estimating the Risk of Plasmodium Vivax Relapses in Afghanistan
• EP1300 Polyepitope DNA Vaccine Against Plasmodium Falciparum Malaria
• Study of Malaria Treatment at Phuoc Long Hospital, Binh Phuoc Province, Vietnam
• Pyronaridine/Artesunate -Ritonavir Drug Drug Interaction Study
• Antioxidant Micronutrients in Malaria
• Evaluation of the Riamet® Versus Malarone® in the Treatment of Uncomplicated Malaria
• Effectiveness of the Association Artesunate and Mefloquine in the Treatment of Malaria by Plasmodium Falciparum
• Pharmacokinetics and Pharmacodynamics of Intravenous Artesunate for Severe Malaria Treatment
• Artesunate+Sulfadoxine-Pyrimethamine for the Treatment of Uncomplicated Falciparum Malaria
• Study of Iron Absorption and Utilization in Asymptomatic Malaria
• Efficacy of Artemisinin Combination Therapies for the Treatment of Uncomplicated P. Vivax in Pregnancy in Brazil (PAACT-PV)
• Safety Study on the Effect of Eurartesim™ on QT/QTc Interval Compared to Riamet in Healthy Volunteers
• Evaluate Azithromycin Plus Chloroquine And Sulfadoxine Plus Pyrimethamine Combinations For Intermittent Preventive Treatment Of Falciparum Malaria Infection In Pregnant Women In Africa
• A Phase 1 Study To Estimate The Relative Bioavailability Of Co-Administered Formulations Of Azithromycin Microsphere And Chloroquine Test Formulation Compared With Co-Administered Immediate Release Individual Azithromycin And Chloroquine Tablets In
• Intermittent Preventive Treatment Versus Scheduled Screening and Treatment of Malaria in Pregnancy
• Efficacy of Artemisinin Combination Therapies for the Treatment of Uncomplicated P. Falciparum in Pregnancy in Brazil
• Pharmacokinetics of Mefloquine-Artesunate in Pregnant Women With Uncomplicated Plasmodium Falciparum Infection
• Assessing the Efficacy of Artemisinin Combination Therapies for Treatment of Uncomplicated Malaria Infection in Children
• Safety and Immunogenicity Study of Plasmodium Vivax CS Derived Synthetic Peptides Formulated in Two Adjuvants
• Incidence of Vivax Along the Thai Burma Border
• Dihydroartemisinin- Piperaquine Versus Artemether- Lumefantrine in the Treatment Uncomplicated Plasmodium Falciparum Malaria in Sudan
• Study on the Treatment of Vivax Malaria
• Artemether-Lumefantrine (AL) Unit Dose Pre-packs Versus Blister Packs
• Randomised Trial of 3 Artemisinin Combination Therapy for Malaria in Pregnancy
• Establishing Effectiveness of Daily Co-trimoxazole Prophylaxis For Prevention of Malaria in Pregnancy
• Ethiopia Malaria Therapeutic Efficacy Study
• Efficacy of ArTiMist™ in Children
• Non-malarial Febrile Illness in Children in Areas of Perennial Malaria Transmission
• Safety and Effectiveness of Artemisinin-based Combination Therapies (ACTs) With Repeated Treatments for Uncomplicated Falciparum Malaria Over a Three-year Period
• EBA-175 RII-NG Malaria Vaccine Administered Intramuscularly in Semi-immune Adults
• Artesunate Plus Amodiaquine in Malaria in Cote d'Ivoire
• Extended-dose Chloroquine (ECQ) for Resistant Falciparum Malaria Among Afghan Refugees in Pakistan
• Adenovirus Type 35 Based Circumsporozoite Malaria Vaccine in Burkina Faso
• Artemether-lumefantrine (AL) Versus Artesunate + Amodiaquine (ASAQ) for the Treatment of Uncomplicated Falciparum Malaria in Burkina Faso
• Fosmidomycin With Clindamycin or With Clindamycin Plus Artesunate
• Protease Inhibitors to Reduce Malaria Morbidity in HIV-Infected Pregnant Women
• Dose Ranging Study of Ferroquine With Artesunate in African Adults and Children With Uncomplicated Plasmodium Falciparum Malaria
• Weekly Dosing of Malarone ® for Prevention of Malaria
• Safety and Efficacy Study of Artesunate and Mefloquin in Children With Uncomplicated Malaria
• HIV Protease Inhibitors for the Prevention of Malaria in Ugandan Children
• Prevention of Pregnancy-associated Malaria in HIV-infected Women: Cotrimoxazole Prophylaxis Versus Mefloquine
• A Randomized Controlled Trial for Intermittent Preventive Treatment in Pregnancy With Fansidar in Solomon Islands
• Trial of Artesunate Combination Therapy in Pakistan
• Therapeutic Efficacy Study of Pyrimethamine/Sulfdoxine (Fansidar®) for the Treatment of Uncomplicated Falciparum Malaria in the Peruvian Amazon
• Chemopreventive Therapy for Malaria in Ugandan Children
• Intermittent Preventive Treatment (IPTc) and Home Based Management of Malaria (HMM)in The Gambia
• Dihydroartemisinin (DHA)-Piperaquine for IPT to Prevent Malaria in Children in Burkina Faso
• Clinical Evaluation of Insect Repellent and Insecticide Treated Nets in Lao PDR
• Artemisone for the Treatment of Uncomplicated Falciparum Malaria in Western Cambodia
• A Study to Investigate the Safety, Tolerability and Pharmacokinetics of OZ439 in Healthy Male and Female Subjects
• Efficacy of Methylene Blue for Malaria Treatment in Adults of Burkina Faso: Proof of Principle Study in Semi-Immune Adults of Burkina Faso in the Frame of the A8 Project of the SFB 544
• Effectiveness of Artemisinin Combination Regimens in Falciparum Malaria
• Phase I Study of the Safety and Immunogenicity of BSAM-2/Alhydrogel +CPG 7909, an Asexual Blood Stage Vaccine for Plasmodium Falciparum Malaria in Adults in the US and Mali
• Interactions Between Artemether-lumefantrine and Antiretrovirals in HIV-patients With Uncomplicated Malaria in Tanzania
• Impact of Malaria Prevention on Health and Education in Kenyan Schoolchildren
• Tafenoquine/Chloroquine DDI Study
• Pharmacokinetic Interaction Between the Antimalarial Combination Artemether/Lumefantrine and Combination Antiretroviral Therapy Including Lopinavir/Ritonavir in HIV-infected Adults
• Treatment Efficacy and Malaria TRANSmission After Artemisinin Combination Therapy (TRANSACT)
• Intermittent Preventive Treatment for Malaria in Infants in Navrongo Ghana
• Safe and Efficacious Artemisinin-based Combination Treatments for African Pregnant Women With Malaria
• Intermittent Preventive Treatment of Malaria in Schoolchildren
• Pharmacokinetics of Dihydroartemisinin-Piperaquine in the Treatment of Uncomplicated Malaria in Children in Burkina Faso
• A Phase 1 Study To Estimate The Relative Bioavailability Of Fixed Combination Tablets Of Azithromycin And Chloroquine Compared To Co-Administered Individual Tablets Of Azithromycin And Chloroquine
• Evaluation of Alternative Antimalarial Drugs for Malaria in Pregnancy
• A First Time in Human Study in Healthy Volunteers to Investigate a New Medicine to Treat Malaria
• Pilot Human Study of Tinidazole Efficacy For Radical Cure Of Plasmodium Vivax
• In Vivo and in Vitro Efficacy of Antimalarial Treatments in Children in Burkina Faso
• Assessment of Safety and Pharmacokinetics of a Low Dose of Methotrexate in Healthy Adult Male Kenyan Volunteers
• Artemether/Lumefantrine and Nevirapine Interaction Study in HIV-infected Adults
• Intermittent Preventive Treatment in Infant in Mali
• Merozoite Surface Protein 1 Antibody Response in Asymptomatic Human Malaria Infection
• Malaria Vaccine for Children in Mali
• Study of SAR97276A in the Treatment of Uncomplicated and Severe Malaria in Adults and Children.
• A Trial of the Combined Impact of Intermittent Preventive Treatment and Insecticide Treated Bednets in Reducing Morbidity From Malaria in African Children
• New Approaches to Improve Coverage and Compliance of Antimalarial Treatment for Pregnant Women in Rural Africa
• Treatment of Non-falciparum Malaria
• Assessment of Use of Rapid Diagnostic Testing in the Context of Home Management With ACTs
• Differences in Malaria Infection Levels in HIV-infected Infants and Children Receiving PI- and NNRTI-based HAART
• Evaluation of the Public Health Impact of Seasonal Intermittent Preventive Treatment (IPT) in Children in Senegal
• Daily Co-trimoxazole Prophylaxis to Prevent Malaria in Pregnancy
• Evaluation of Safety and Efficacy of Artemether-Lumefantrine Tablets in African Infants and Children With Uncomplicated P. Falciparum Malaria
• Pharmacokinetic of Mefloquine-Artesunate in Plasmodium Falciparum Malaria Infection in Pregnancy
• Cohort Study in Uganda Comparing Artesunate + Amiodaquine (Coarsucam) Versus Artemether + Lumenfantrine (Coartem) in the Treatment of Repeated Uncomplicated Plasmodium Falciparum Malaria Attacks
• Pharmacokinetic Interactions Between Antiretroviral Agents and Antimalarial Drug Combinations
• Randomized Trial of Erythropoietin During Cerebral Malaria
• Azithromycin + Artesunate v Artemether-lumefantrine in Uncomplicated Malaria.
• Bioequivalence of Pyronaridine Artesunate To-be-marketed Tablet to the Clinical Trial Reference Tablet
• A Comparative Study of Artekin With Standard Malarial Treatment Regimes in Afghanistan
• Prevention of Intrauterine Growth Retardation in Burkina Faso: the Malaria Component
• Azithromycin Plus Chloroquine Versus Artemether-Lumefantrine For The Treatment Of Uncomplicated P. Falciparum Malaria In Children In Africa
• Single-Blind, Placebo-Controlled, Randomized Study Testing Single Ascending Doses Of GSK369796 In Healthy Subjects
• Antimalarial Treatments for Clearing Low Density P. Falciparum and Its Impact on Malaria Transmission
• Artemisinin Resistance in Bangladesh
• Seasonal Intermittent Preventive Treatment With Sulfadoxine-Pyrimethamine in Children in Mali
• Safety and Preliminary Efficacy of L-arginine in Severe Falciparum Malaria
• ACT for the Home Management in Malagasy Children
• A Comparative Safety and Activity Study With Ferroquine Associated With Artesunate Versus Amodiaquine Associated With Artesunate in African Adult Patients With Uncomplicated Malaria
• Comparison of Three Drug Combinations for Intermittent Treatment of Malaria in Children
• The Synergistic Effects of Home-management and Intermittent Preventive Treatment of Malaria in Children
• Safety and Efficacy of Methylene Blue Combined With Amodiaquine or Artesunate for Malaria Treatment in Children of Burkina Faso
• Pyronaridine Artesunate 3:1 Granule Formulation vs. Coartem© Crushed Tablets in P. Falciparum Malaria Pediatric Patients
• Cohort Study in Senegal Comparing Artesunate + Amiodaquine in the Treatment of Repeated Uncomplicated Plasmodium Falciparum Malaria Attacks
• Effectiveness of Oral Quinine and Artemether-Lumefantrine in the Treatment of Uncomplicated Malaria in Ugandan Children
• Study of Pharmacokinetics and Pharmacodynamics of Artesunate in Pregnant Women in the Democratic Republic of Congo
• Randomised Efficacy Study of Two Artemether-Lumefantrine Oral Formulations for the Treatment of Uncomplicated P. Falciparum Malaria
• Three Alternative Drug Regimens for Malaria Seasonal Preventive Treatment in Senegal
• Interactions Between HIV and Malaria in African Children
• Phase II Artesunate Study in Severe Malaria
• Safety and Efficacy Dose of Artesunate Used in Combination With LAPDAP Treatment of Uncomplicated Falciparum Malaria
• Zambia Integrated Management of Malaria and Pneumonia Study
• Mass-Drug Administration to Reduce Malaria Transmission
• The Effect of Malaria on Disease Progression of HIV/AIDS
• RCT Iron Supplementation and Malaria Chemoprophylaxis for Prevention of Severe Anemia and Malaria in Tanzanian Infants
• Quinine vs. Artemether/Lumefantrine in Uncomplicated Malaria During Pregnancy
• Clinical Investigation of In-vivo Susceptibility of P.Falciparum to Artesunate in Western Cambodia
• Phase 1 Study of the Safety, Reactogenicity, and Immunogenicity of AMA1-C1/ISA 720: Blood Stage Vaccine for Plasmodium Falciparum
• Artesunate Plus Sulfadoxine-Pyrimethamine Versus Chloroquine for Vivax Malaria
• Multi-Centre Trial Comparing Three Artemisinin-Based Combination Treatments on P. Falciparum Malaria
• Artemisinin Resistance in Cambodia
• Chloroquine and Post Malaria Anaemia Study
• Efficacy of Artesunate + Amodiaquine Four Years After Its Introduction in Zanzibar
• Tolerability and Efficacy of CD+A Compared to AQ+SP for the Treatment of P.Falciparum Malaria in Rwandan Children
• Treatment of Uncomplicated Malaria in Benin
• Phase II Dose Ranging Study of Artesunate
• Food-Effect Bioavailability Study of AQ-13, a Candidate Antimalarial
• Effectiveness of Artemether-Lumefantrine for Malaria Treatment of Children at Community Level in Tanzania
• Efficacy of Sulfadoxine-Pyrimethamine for Treating Malaria in Gabonese Children
• ACT MALI: Treatment of Malaria Based on Combination Therapies
• Ototoxicity of Artemether / Lumefantrine (Coartem) and Other Antimalarials
• Arsucam® (Artesunate + Amiodaquine) Efficacy and TOLerance
• Evaluation of Potential Effect of Artemether - Lumefantrine and Malaria Drugs on Auditory Function
• Safety and Efficacy of Chloroquine Associated With Dehydroepiandrosterone Sulphate to Treat Uncomplicated Falciparum Malaria
• Pyronaridine Artesunate (3:1) in Children and Adults With Acute Plasmodium Vivax Malaria
• Intermittent Preventive Treatment (IPTp) Versus Rapid Diagnostic Testing (RDT) and Treatment of Malaria in Pregnancy
• Phase I Study of AMA1-C1/Alhydrogel® (Registered Trademark) + CPG 7909 Malaria Vaccine
• Chloroquine and Coartem for Treatment of Symptomatic Children With Plasmodium Falciparum in Guinea Bissau
• Efficacy of Amodiaquine-artesunate in Children Aged 6-59 Months With Uncomplicated P. Falciparum Malaria
• Pyronaridine Artesunate (3:1) Versus Coartem® in P Falciparum Malaria Patients
• Drug Interaction Study Between Atovaquone and Antiretroviral Agents in HIV-1 Infected Patients
• Assessment of Anaemia Attributable to Schistosomiasis in School Children in Kenya: Mechanisms and Effect of Treatment
• Phase I Study of Safety and Immunogenicity of AMA1-C1Alhydrogel + CPG 7909 Vaccine for Malaria
• Prophylactic Antimalarial Activity of DB289 in Volunteers
• Amodiaquine+Artesunate vs. Artemether-Lumefantrine for Uncomplicated Malaria in Ghanaian Children
• Pyronaridine - Artesunate (3:1) Versus Mefloquine Plus Artesunate in Plasmodium Falciparum Malaria Patients
• Sulfadoxine- Pyrimethamine Versus Weekly Chloroquine for Malaria Prevention in Children With Sickle Cell Anemia
• Evaluation of 4 Artemisinin-based Combinations for Treating Uncomplicated Malaria in African Children
• Efficacy and Safety of the Pediatric Formulation of Artemether- Lumefantrine in Children With Uncomplicated P. Falciparum Malaria.
• Safety of Artemether - Lumefantrine, and Other Malaria Drugs and Their Effect on the Auditory Function
• Bioavailability of the Fixed Combination of Amodiaquine and Artesunate Under Fed & Fasted Conditions
• Pharmacokinetics, Efficacy, Gametocyte Carriage, Birth Outcomes Following Sulfadoxine-pyrimethamine Intermittent Presumptive Treatment in Pregnant Women
• Chloroquine Alone or in Combination for Malaria in Children in Malawi
• Efficacy, Effect on Gametocytes and Tolerability of the Addition of Artesunate to Amodiaquine in Colombia
• Comparison of Two Strategies for the Delivery of IPTc
• Randomized Trial on Effectiveness of ACTs in Ghana
• Efficacy and Safety of Dihydroartemisinin/Piperaquine (Artekin®) for the Treatment of Uncomplicated Malaria in Peru
• IPT of Malaria With SP in Different Zones of Drug Resistance in Rwanda
• Chlorproguanil-Dapsone-Artesunate (CDA) Versus Chlorproguanil-Dapsone (LAPDAP) For Uncomplicated Malaria
• Adenovirus Vaccine for Malaria
• Azithromycin Plus Chloroquine Versus Mefloquine In the Treatment of Uncomplicated P. Falciparum Malaria.
• RBx11160 Phase II Dose Ranging Study RBx/MMV05-06
• IPT and Efficacy of Sulphadoxine/Pyrimethamine and Chlorproguanil/Dapsone in 6-59 Month Old Children With Malaria.
• Relationship Between HIV and Malaria in Ugandan Children
• Azithromycin Combination Therapy for the Treatment of Uncomplicated Falciparum Malaria in Bangladesh
• Safety and Efficacy of Methylene Blue Combined With Artesunate or Amodiaquine for Malaria Treatment in Children of Burkina Faso: a Pilot Study
• Safety and Immunogenicity of EBA-175 RII-NG Malaria Vaccine Administered Intramuscularly
• Schistosome and Intestinal Worm Infections and Malaria Morbidity Among School and Pre-school Children in, Tanzania
• Chlorproguanil-Dapsone-Artesunate Versus COARTEM For Uncomplicated Malaria
• Experimental Vaccine for Malaria in Adults in Mali
• Malaria Vaccine in Children in Mali
• Improving the Efficacy of Experimental Malaria Vaccine AMA1-C1/Alhydrogel® (Registered Trademark)
• Experimental Vaccine for Plasmodium Falciparum Malaria
• Treatment of Uncomplicated Childhood Malaria in Tanzania by Artemether+Lumefantrine - Efficacy and Genotyping
• Artesunate Plus Sulfadoxine-pyrimethamine Pharmacokinetics, Efficacy, Gametocytes Carriage and Birth Outcomes in Pregnant Women With Malaria
• Pyronaridine and Artesunate (3:1) in Children With Acute Uncomplicated Plasmodium Falciparum Malaria
• Randomized Trial of Two Antimalarial Treatments for Clearing Low Density P.Falciparum Parasitaemia in Sudan
• Investigation of the Efficacy of Quinine Sulphate Administered Via Taste-Masked Pellets to Children With Falciparum Malaria
• Long-Term Follow-up of Children for a 2-Year Period to Confirm the Safety and Immunogenicity of GSK 257049 Vaccine
• Studies of AQ-13, a Candidate Aminoquinoline Antimalarial, in Comparison With Chloroquine
• Cotrifazid Safety and Efficacy Against Malaria
• ATAQ EASY: Artesunate + Amodiaquine Fixed Dose Combination in the Treatment of Uncomplicated Plasmodium Falciparum Malaria
• Comparative Evaluation of the Safety and the Efficacy of 2 Antimalarials Depending on HIV Status
• SP Resistance and Falciparum Malaria Transmission
• Azithromycin Combination Therapy for Malaria
• Safety and Efficacy Study of IV Artesunate to Treat Malaria
• Artemisinin-Based Combination Therapy: Clinical Trials in Cameroon
• PpPfs25/ISA51 and ScPvs25/ISA51 Vaccines for Malaria
• Early Childhood Malaria Prevention With Maloprim in The Gambia
• Study of the Safety of Intravenous Artesunate
• Study of the Safety of Intravenous Artesunate
• Prevention of P. Vivax Malaria During Pregnancy in Bolivia
• Effect of Antimalarial Treatment on Gametocyte Carriage in Asymptomatic P. Falciparum
• Efficacy and Safety of Azithromycin and Artesunate in Pregnant Women
• Intermittent Preventive Treatment (IPTi) for the Prevention of Malaria and Anaemia in PNG Infants
• A Three Day Trial of Azithromycin Plus Chloroquine for the Treatment of Uncomplicated Plasmodium Falciparum Malaria
• Intermittent Preventive Treatment During Pregnancy in Benin
• Intermittent Preventive Treatment of Malaria in HIV-Seropositive Pregnant Women in Zambia
• Drug Interaction Study Between Antimalarial and Anti-HIV Medications
• Efficacy of Amodiaquine in the Treatment of Uncomplicated Falciparum Malaria in Young Children of Burkina Faso
• Acceptability and Cost Effectiveness of Home Based Management of Fever: Different Strategies
• Control of Pregnancy Associated Malaria With Intermittent Preventive Treatment
• Efficacy, Safety and Pharmacokinetic of ArtequinTM P. Falciparum Malaria
• Efficacy and Safety of Amodiaquine and Amodiaquine-Artesunate
• Efficacy, Safety and Tolerability of Co-artemether in Non-immune Travelers
• Age of Exposure and Immunity to Malaria in Infants
• Efficacy of Chloroquine + Sulfadoxine Pyrimethamine Versus Artemether + Lumefantrine for the Treatment of Uncomplicated Plasmodium Falciparum Malaria in the Philippines
• Treatment of Malaria in Gabon With Fosmidomycin-Clindamycin
• The Effect of Praziquantel Treatment on Schistosoma Mansoni Morbidity and re-Infection Along Lake Victoria, Uganda
• Efficacy of Fosmidomycin-Clindamycin for Treating Malaria in Gabonese Children
• IPTi in Mozambican Infants for Malaria Prevention
• IPTp Plus ITNs for Malaria Control in Pregnant Women
• Intermittent Treatment With Sulfadoxine-pyrimethamine for Malaria Control in Infants
• A Randomised Efficacy Study of Combination Antimalarials to Treat Uncomplicated Malaria
• Combination Antimalarials in Uncomplicated Malaria
• A Randomised Efficacy Study of Combination Antimalarials to Treat Uncomplicated Malaria
• Impact of Insecticide-treated Curtains on Antimalarial Drug Resistance
• Intermittent Antimalaria Treatment With SP in African Children
• Reducing the Effects of Malaria in Children by Administering Repeated Preventive Doses
• Treatment of Malaria With Quinine Plus Sulfadoxine-Pyrimethamine
• Treatment of Fever Due to Malaria With Ibuprofen
• Assessing the Efficacy of Four Drug Combinations as the Next First-line Therapy for Uncomplicated Malaria in Malawi
• Amodiaquine Plus Artesunate Versus Lapdap Plus Artesunate in the Treatment of Uncomplicated P. Falciparum Malaria in Malawi
• Efficacy of Combination Therapy for Prevention of Effects of Malaria During Pregnancy
• Efficacy and Effectiveness of Combined Therapy for Uncomplicated Malaria Treatment in Peru
• Eight Week Primaquine Regimen for the Treatment of Vivax Malaria
• Kilimanjaro IPTi Drug Options Trial
• Chlorproguanil/Dapsone Compared With Chloroquine and SP for Vivax Malaria
• ACT With Chloroquine, Amodiaquine & Sulphadoxine-pyrimethamine in Pakistan
• A Randomised Trial of Artekin and Artesunate & Amodiaquine for Uncomplicated Malaria in Timika, Papua, Indonesia.
• To Evaluate Current Efficacy of Antimalarials Used in Timika, Papua, Indonesia
• A Randomized Trial of Coartemether and Artekin for the Treatment of Uncomplicated Malaria in Papua, Indonesia.
• Adherence to Lumefantrine-Artemether
• The Community Effectiveness of IPTi in Southern Tanzania
• Safety and Efficacy Study of Adjunctive Rosiglitazone in the Treatment of Uncomplicated Falciparum Malaria
• Arginine Malaria Trial: Study of Adjunctive Arginine in Falciparum Malaria
• Navrongo Drug Options for IPT in Pregnancy Trial
• A Trial of Antimalarial Drugs Used in Pregnancy in Tanzania
• Anti-Malarial Drug Resistance in Cameroon
• In-Vivo Response of P. Falciparum to Antimalarial Treatment in HIV-Infected and HIV-Uninfected Adults
• Study of the Impact of Intermittent Preventive Treatment in Schools on Malaria, Anaemia and Education.
• Preventing Malaria During Pregnancy in Epidemic-prone Areas.
• Relationships Between the Use of Antimalarial Drugs in Pregnancy and Plasmodium Falciparum Resistance
• Efficacy of Sulphadoxine-pyrimethamine and Artemisinin-containing Combination Therapy for Malaria
• Impact of Cotrimoxazole Prophylaxis for HIV-Infected Adults on Antifolate Resistance
• The Effect of Paracetamol in the Treatment of Non-severe Malaria in Children in Guinea-Bissau
• The Efficacy of Re-treatment With Sulfadoxine-pyrimethamine in Children
• Chloroquine and Amodiaquine for Treatment of Malaria in Children
• Pentoxifylline in Children With Malaria
• A Trial of Intermittent Treatment in the Prevention of Malaria in Senegalese Children
• A Trial of Four Drug Regimens for the Prevention of Malaria in Senegalese Children
• Influence of Chloroquine on HIV Viral Load Among Pregnant Women in Uganda
• Efficacy and Safety of Sulphadoxine-pyrimethamine and Amodiaquine in Ghanaian Pregnant Women
• Gestational Sulfadoxine-pyrimethamine and Azithromycin Treatment to Prevent Preterm Birth
• The Effect of Folic Acid on Efficacy of Sulfadoxine-pyrimethamine in Pregnant Women in Western Kenya
• Antimalarial Drug Resistance in Mali
• Chlorproguanil-Dapsone in Pregnant Women
• Prevention of Malaria During Pregnancy Using Intermittent Preventive Treatment With Sulfadoxine-Pyrimethamine: Malawi
• CQSP in Malawi: Chloroquine and Sulfadoxine-pyrimethamine Efficacy for the Treatment of Malaria in Malawi
• Efficacy of Intrarectal Versus Intravenous Quinine for the Treatment of Childhood Cerebral Malaria
• Longitudinal Antimalarial Combinations in Uganda
• Folic Acid Supplementation in Gambian Primigravidae
• Intermittent Preventative Treatment With Sulfadoxine-Pyrimethamine in Gambian Multigravidae
• Kintampo Trial of Combination Therapy for Malaria
• Effectiveness of Intermittent Preventive Treatment for Malaria in Children
• Trial of the Effectiveness of AQ/AS, SP/AQ and SP/CQ for Uncomplicated Malaria in Gambian Children
• Lapdap and Coartemether for Uncomplicated Malaria
• A New Approach to Deliver Malaria Preventions to Pregnant Women at a Community Level in Uganda
• Experimental Vaccine for Malaria
• Mannitol as Adjunct Therapy for Childhood Cerebral Malaria
• Intermittent Preventive Treatment With Antimalarials in Kenyan Infants
• Azithromycin Plus Chloroquine Versus Sulfadoxine-Pyrimethamine Plus Chloroquine For The Treatment Of Uncomplicated, Symptomatic Falciparum Malaria In Southeast Asia
• Azithromycin Plus Chloroquine Versus Atovaquone-Proguanil For The Treatment Of Uncomplicated Plasmodium Falciparum Malaria In South America
• Azithromycin Plus Chloroquine Versus Mefloquine for the Treatment of Uncomplicated Malaria in Africa
• Trial of Azithromycin Plus Chloroquine Versus Sulfadoxine-Pyrimethamine Plus Chloroquine for the Treatment of Uncomplicated Malaria in India