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Clinical Trials for Cognitive Dysfunction

• Study to Assess Safety and Efficacy of PRI-002 in Patients With MCI to Mild Dementia Due to Alzheimer's Disease (AD)
• MCLENA-2: A Phase II Clinical Trial for the Assessment of Lenalidomide in Patients With Mild Cognitive Impairment Due to Alzheimer's Disease
• Stellate Ganglion Block in Patients With Cerebral Small Vessel Disease
• Impact of Desflurane and Sevoflurane on Postoperative Delirium in Elderly Patients
• The Effects of DPPIs on Cognitive Function of Diabetic Patients
• Cognitive Function and Glymphatic System in Children With Epilepsy
• Cognitive Dysfunction and Inflammation in Depression: Experimental Inhibition Via Infliximab
• A Trial of SHR-1707 Infusion in Patients With Mild Cognitive Impairment Due to Alzheimer's Disease and Mild Alzheimer's Disease
• Effects of Henagliflozin on the Brain Function in T2DM Patients With Mild Cognitive Impairment: a Randomized, Parallel Controlled Clinical Trial
• COMMETS- Combination MCI Metabolic Syndrome
• Single-dose Ketamine Treatment to Improve Depression in Mild Cognitive Impairment
• Amantadine Therapy for Cognitive Impairment in Long COVID
• Extension Study of Idursulfase-IT Along With Elaprase in Children and Adults With Hunter Syndrome and Cognitive Impairment
• NMDA-enhancing Treatment for Cognitive Dysfunction of Schizophrenia
• Attentional Mechanisms in SCD
• Methylprednisolone in Patients With Cognitive Deficits in Post-COVID-19 Syndrome (PCS)
• Epileptic Hippocampus in Alzheimer's Disease
• [18F]MC225-PET in Neurodegenerative Disease
• The Effect of Intraoperative Hypotension on Postoperative Cognitive Functions in Cesarean Section Operations
• Metformin Treatment on Cognitive Impairment of Schizophrenia
• An Investigation of Psilocybin on Behavioural and Cognitive Symptoms of Adults With Fragile X Syndrome
• CBD for Individuals at Risk for Alzheimer's Disease
• EfFect of Ablation of Persistent AtriaL Fibrillation on COgNitive Function in Individuals With Mild Cognitive Impairment
• Effect of Equol Supplementation on Arterial Stiffness and Cognition in Healthy Volunteers
• Clinical Study of Angong Niuhuang Pill and Acupuncture on PSCI Angong Niuhuang Pill Combined With Supervised Pulse Music Electroacupuncture on Cognitive Impairment After Ischemic Stroke
• Randomized Clinical Trial of Donepezil for the Treatment of Mild Cognitive Impairment in Parkinson's Disease
• Ketamine as a Treatment for Depressive Symptoms Among Patients With Post-acute Sequelae of COVID (PASC): A Pilot Trial
• Effect of Epidural Analgesia on Burst Suppression
• A Study to Evaluate RL-007 in the Treatment of Cognitive Impairment Associated With Schizophrenia (CIAS)
• Feasibility Study on the Use of Redormin®500 on Day-time Cognition
• Xanamem® in Adults With Major Depressive Disorder and Impaired Cognition (XanaCIDD)
• Technical R&D and Demonstration of Intelligent Medical Care in Alzheimer's Disease's Management
• A Study to Evaluate the Effects of SAGE-718 in Participants With Mild Cognitive Impairment or Mild Dementia Due to Alzheimer's Disease (AD)
• Innate Immunity Stimulation Via TLR9 in Early AD
• Minocycline In Neurocognitive Outcomes - Sickle Cell Disease
• Addressing Cognitive Fog in Long-COVID Patients
• Role of Silymarin in Chemotherapy Toxicity and Cognition Improvement in Breast Cancer Patients
• Effect of Treatment With EGb 761(r) on Blood Markers of Inflammation and Oxidative Stress in Patients With MCI
• Pharmacological Modulation of Brain Oscillations in Memory Processing
• δ in Dementia Clinical Trials
• Safety and Target Engagement of Centella Asiatica in Cognitive Impairment
• Electronic Training of Elderly Depression With Cognitive Impairment
• Statins in Reducing Events in the Elderly Mind (STAREE-Mind) Imaging Substudy
• The Caffeine, Postoperative Delirium, and Change in Outcomes After Surgery (CAPACHINOS-2) Study
• Dapagliflozin Effect in Cognitive Impairment in Stroke Trial
• The Effect of Huperzine A Injection on Postoperative Cognitive Dysfunction in Patients With Aneurysmal Subarachnoid Hemorrhage: a Pilot Study
• Effects of Different Doses of Vitamin D on Cancer-related Cognitive Impairment in Patients With Gastrointestinal Tumors
• [18F]APN-1607 PET in Subjects With AD Compared to HC
• Efficacy of Chinese Traditional Medicine "Smart Soup" in Cognition and Behavior Regulation in Alzheimer's Disease
• RCT of Brain Longitudinal Biomarker Study (OPT-Neuro RCT)
• An Open-Label Extension of XPro1595 in Patients With Alzheimer's Disease
• MIBG in Aging and Neurologic Disorders
• Study of Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of NIO752 in Early Alzheimer's Disease Participants
• Safety and Feasibility of Exablate Blood-Brain Barrier Disruption for Mild Cognitive Impairment or Mild Alzheimer's Disease Undergoing Aduhelm Therapy.
• A Study of MK-2214 in Adults With Mild Cognitive Impairment or Mild-to-Moderate Alzheimer's Disease (MK-2214-002)
• MW151 and HA-WBRT in Patients With Brain Metastases
• A Study to Assess the Efficacy, Safety, and Tolerability of BIIB080 in Participants With Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease (AD) or Mild Alzheimer's Disease Dementia
• Propofol and Dexmedetomidin vs Midazolam Intraoperative Sedation and POCD
• Tau Pet Imaging in the Aging Brain Cohort Dedicated to Diversity Study
• Efficacy and Safety of Tian Ma Bian Chun Zhi Gan Tablets in Mild to Moderate Vascular Dementia
• Ca-Mg Butyrate in GWI
• Impact of Structural and Myelin Abnormalities on Cognitive Impairments in Recent-onset Schizophrenia - Before and After Lurasidone Treatment (MARYLU)
• Effects of Thoracic Paravertebral Block Combined With S-ketamine on Postoperative Pain and Cognitive Function After Thoracoscopic Surgery
• Istradefylline for Parkinson Disease With Cognitive Impairment
• Impact of Intensive Treatment of SBP on Brain Perfusion, Amyloid, and Tau (IPAT Study)
• Study to Assess the Efficacy of XPro1595 in Patients With Mild Cognitive Impairment With Biomarkers of Inflammation
• A Study to Evaluate the Effects of SAGE-718 in Participants With Parkinson's Disease Cognitive Impairment
• Effects of Liraglutide, Empagliflozin and Linagliptin on the Cognitive Function in T2DM Patients With Mild Cognitive Impairment: a Multicenter, Randomized, Parallel Controlled Clinical Trial
• Effects of S-ketamine and Continuous Iliac Fascia Space Block on Perioperative Neurological Cognitive Impairment and Postoperative Rehabilitation in Elderly Patients With Hip Fracture
• Diminishing Accelerated Long-term Forgetting in Mild Cognitive Impairment
• Targeting Cognition in Early Alzheimer's Disease by Improving Sleep With Trazodone
• Perioperative Multimodal General AnesTHesia Focusing on Specific CNS Targets in Patients Undergoing carDiac surgERies - the PATHFINDER II Study
• Influence of Fampridine on Working Memory in Individuals With Post COVID-19 Condition With Subjective Cognitive Impairment
• RAGE Inhibition to Decrease Cancer Related Cognitive Decline (CRCD) in Women With Non-metastatic Breast Cancer
• GM1 Prophylaxis for Post-chemotherapy Cognitive Impairment in Patients With Early Operable Breast Cancer
• Phase II Open Label Study for the Use of Insulin-Sensitizer for Treatment of Cognitive Decline
• Evaluation of Trazodone in OSA-MCI
• A Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of SDI-118 in Elderly Male and Female Study Participants With Cognitive Decline
• Neurodegenerative Alzheimer's Disease and Amyotrophic Lateral Sclerosis (NADALS) Basket Trial
• Study to Evaluate the Efficacy, Safety, and Tolerability of Luvadaxistat in Subjects With Cognitive Impairment Associated With Schizophrenia
• Polipill and RiscOMeter to Prevent StrOke and CogniTive ImpairmEnt (PROMOTE)
• Esketamine vs. Ketorolac for Prevention of Postoperative Pain and Cognitive Dysfunction After Total Knee Arthroplasty
• Development and Evaluation of Computerized Olfactory Training Program for Cognitive Decline in Early Alzheimer's Disease
• A Study of Donanemab (LY3002813) Compared With Aducanumab in Participants With Early Symptomatic Alzheimer's Disease (TRAILBLAZER-ALZ 4)
• A Study of CST-2032 and CST-107 in Subjects With Mild Cognitive Impairment or Mild Dementia Due to Parkinson's or Alzheimer's Disease
• SNIFF - Combo INI+EMPA Trial
• A Clinical Trial to Evaluate the Efficacy and Safety of Choline Alfoscerate in Vascular Cognitive Impairment Patients
• A Clinical Trial to Evaluate the Efficacy and Safety of Choline Alfoscerate Compared to Placebo in Patients With Degenerative Mild Cognitive Impairment
• A Study of CST-2032 in Subjects With Cognitive Impairment
• Dexmedetomidine or Clonidine Infusion for Prevention of Delirium After Open Heart Surgery
• The Effects of Cannabidiol and Homotaurine in Patients With Mild Cognitive Impairment
• SNIFF - 3-Week Aptar CPS Device
• A Double-Blind, Placebo-Controlled, Dose Ranging Study of Xanamem® in Healthy Elderly Volunteers
• A Study to Assess Safety and Target Engagement of E2814 in Participants With Mild to Moderate Cognitive Impairment Due to Dominantly Inherited Alzheimer's Disease
• Safety and Efficacy of Maraviroc in Post-stroke Cognitive Impairment
• Treatment of Mild Vascular Cognitive Impairment With Yangxue Qingnao Pill
• Influence of Postoperative Cognitive Function in Patients With Sevoflurane Postconditioning on Carotid Intima Stripped
• Effect of Propfol Versus Sevoflurane on Auditory and Cognitive Function
• Parkinson's Disease With Mild Cognitive Impairment Treated With Nicotinic Agonist Drug
• Senicapoc in Alzheimer's Disease
• ALSENLITE: Senolytics for Alzheimer's Disease
• Transcranial Photobiomodulation for Alzheimer's Disease (TRAP-AD)
• Assessing the Role of Cariprazine in Improving Cognition in Euthymic Bipolar Patients
• Evaluate the Effect of Atorvastatin on Cerebrovascular Reactivity in MCI
• Cholinergic Mechanisms of Attention in Aging
• A Study of CST-103 Co-administered With CST-107 in Subjects With Neurodegenerative Disorders
• DAOIB for the Treatment of Mild Cognitive Impairment
• Cognition Platform Study in Participants at Risk for Alzheimer's Disease (AD) (MK-0000-413)
• Cognitive Dysfunction After Cataract Surgery
• Evaluation of Safety of Contraloid Acetate in Patients With Mild Cognitive Impairment Due to Alzheimer's Disease
• Valacyclovir for Mild Cognitive Impairment
• Preventing Stroke, Premature Death and Cognitive Decline in a Broader Community of Patients With Atrial Fibrillation
• Senolytic Therapy to Modulate the Progression of Alzheimer's Disease (SToMP-AD) Study
• Cognitive Effects of Roflumilast in MCI Patients
• Uncovering a Novel Therapeutic Target to Reduce Dementia Risk in Parkinson's Disease
• S-ketamine Prevents Postoperative Pain and Cognitive Dysfunction After Tibial Fracture
• Lidocaine on Early Cognitive Dysfunction in Shoulder Arthroscopy
• Rapamycin - Effects on Alzheimer's and Cognitive Health
• A Study of JNJ-63733657 in Participants With Early Alzheimer's Disease
• Multimodal Biomarkers for Diagnosis and Prognosis in VCI
• A Study to Evaluate the Safety and Tolerability of SAGE-718 in Participants With Mild Cognitive Impairment or Mild Dementia Due to Alzheimer's Disease (AD)
• Trial of CORT108297 to Attenuate the Effects of Acute Stress in the Allocortex (CORT-X)
• Bicarbonate Administration and Cognitive Function in Midlife and Older Adults With CKD
• The Effects of Cannabidiol on the Driving Ability of Healthy Adults
• The Aging Brain and Cognition: Contribution of Vascular Injury, Amyloid Plaque and Tau Protein to Cognitive Dysfunction After Stroke
• The Influence of Sequential Tau Protein and Amyloid Plaque Imaging Changes on Stroke Prognosis and Cognitive Outcome
• Neuroinflammation and Age-associated Brain Pathology: Two Potential Mechanisms of Cognitive Impairment in Ovarian Cancer
• The Effect of Desflurane on Postopertative Cognitive Dysfunction
• Methylene Blue and Postoperative Neurocognitive Disorders
• EGb 761 in the Syndrome of MCI With Concomitant CVD
• Spironolactone Safety in African Americans With Mild Cognitive Impairment and Early Alzheimer's Disease
• Effect of NAC on Preventing Chemo-Related Cognitive Impairments in Ovarian Ca Pts Treated W/ PBT
• Clinical Intervention on Cognitive Impairment of Schizophrenia With Metabolic Syndrome
• Preventing Cognitive Decline With Metformin
• Repurposing Nucleoside Reverse Transcriptase Inhibitors for Treatment of AD
• A Study to Evaluate Safety and Tolerability of Different Doses and Efficacy of PQ912 in Subjects With MCI and Mild AD
• Ginkgo Leaf Extract and Armillariella Mellea Powder Oral Solution for the Treatment of Motoric Cognitive Risk Syndrome
• A Study to Evaluate the Safety and Tolerability of SAGE-718 in Participants With Parkinson's Disease Mild Cognitive Impairment (PD-MCI)
• Dopaminergic Dysfunction in Late-Life Depression
• Flortaucipir PET Imaging in the Preclinical, Prodromal and Dementia Phases of Alzheimer's Disease
• Effect of Vortioxetine on Cognitive Symptoms in Patients With Schizophrenia
• Effects of Nicotinamide Riboside on Bioenergetics and Oxidative Stress in Mild Cognitive Impairment/Alzheimer's Dementia
• Methylphenidate for the Treatment of Epilepsy-related Cognitive Deficits
• Effect of Memantine on Cognitive Impairment in Patients With Epilepsy
• GM1 Prophylaxis for WBRT Related Cognitive Dysfunction
• GnRH Therapy on Cognition in Down Syndrome
• Effect of Antiinflammatory Treatment Versus Hand Training on Neuropsychiatric Comorbidity in RA-patients
• Neuroinflammation and Age-associated Brain Pathology: Two Potential Mechanisms of Cognitive Impairment in Breast Cancer
• Evaluation the Effect of Acetyl-L-carnitine in Patients With Mild Cognitive Impairment Accompanied With Chronic Cerebrovascular Disease
• Intraoperative Infusion of Methylene Blue for Prevention of Postoperative Delirium and Cognitive Dysfunction in Elderly Patients Undergoing Major Elective Noncardiac Surgery
• The Effect of Ketamine on Postoperative Cognitive Dysfunction.
• The Influence of [18F]PMPBB3 and [18F]THK5351 PET Distribution Patterns on Post-stroke Cognitive Impairment
• Treatment for Cognitive Impairment in Depression
• The Influence of Vascular Burden, Amyloid Plaque and Tau Protein in Patients With Vascular Cognitive Impairment and Dementia With Tauopathy
• Efficacy and Safety of Qi Zhi Tong Luo Capsule in Vascular Cognitive Impairment
• Assessing Improvement in Cognitive Deficit in CRS in Patients Treated With Medical Vs Surgical Management
• Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients
• A Pilot Open Labeled Study of Tacrolimus in Alzheimer's Disease.
• Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
• Linking Tau PET to Medial Temporal Lobe Subregions With High Resolution MRI
• Memantine for the Reduction of Cognitive Impairment After Radiation Therapy in Pediatric Patients With Central Nervous System Tumors
• Neuroimmune Dysfunction in Alcohol Use Disorder
• Cognition, Age, and RaPamycin Effectiveness - DownregulatIon of thE mTor Pathway
• SNIFF Multi-Device Study 2
• A Pilot Trial Evaluating the Effect of Tropisetron on Postoperative Cognitive Dysfunction After Cardiac Surgery
• Efficacy and Safety of T-817MA in Patients With Mild Cognitive Impairment Due to Alzheimer's Disease (AD) or Mild AD
• Use of Brain Wave Monitoring During Surgery to Reduce Postoperative Cognitive Dysfunction
• Topography Staging and Dual Phase Image Quantification of Tau PET in Cognitive Impairment Subjects
• NYX-458 in Subjects With Mild Cognitive Impairment or Mild Dementia Due to Parkinson's Disease or Lewy Body Dementia (Cognition, Memory, Attention, Thinking)
• Reducing the Effects of Aging on Cognition With Therapeutic Intervention of an Oral Nutrient (REACTION): A Pilot Trial
• Evaluation of [18F]APN-1607 PET Uptake in Alzheimer's Disease Patients Compared With Healthy Subjects
• Ketamine vs Midazolam on Cognitive Function in Elderly in Elective Surgery Three-Months Postoperatively (ketaminvsMDZ)
• Psilocybin for Depression in People With Mild Cognitive Impairment or Early Alzheimer's Disease
• Modulation of Attention in Event Related Potential (ERPs) as a Marker of Early Cognitive Decline by Ginkgo Biloba
• MIcroglial Colony Stimulating Factor-1 Receptor (CSF1R) in Alzheimer's Disease
• Safety and Modulation of ABCC9 Pathways by Nicorandil for the Treatment of Hippocampal Sclerosis of Aging
• Metformin in Alzheimer's Dementia Prevention
• Ashwagandha for Cognitive Dysfunction
• Cognitive Decline and Alzheimer's Disease in the Dallas Lifespan Brain Study
• Multiple Ascending Dose Putative Cognitive Enhancer VU319
• Clinical Observation for the Therapeutic Effect of mNGF on Cognitive Decline in Cerebral Small Vessel Disease
• Optimal Blood Pressure for the prevenTIon of Major vAscuLar Events in Patients With DIABETES Mellitus (OPTIMAL-DIABETES)
• Optimal Blood Pressure for the prevenTIon of Major vAscuLar Events in Stroke Patients
• Memantine for Prevention of Cognitive Decline in Patients With Breast Cancer
• MCLENA-1: A Clinical Trial for the Assessment of Lenalidomide in Amnestic MCI Patients
• Evaluation of the Effect of Preoperative Intravenous Amantadine Sulfate on the Postoperative Early Cognitive Functions in a Elderly Patient With Laparoscopic Radical Prostatectomy
• 11C-PIB PET Study in MESA at Columbia University
• Use of Melatonin for Preventing POCD in Transurethral Prostate Resection Under Spinal Anesthesia
• Effects of Liraglutid, Dapagliflozin and Acarbose on the Cognitive Function, Olfactory Function, and Odor-induced Brain Activation in Overweight/Obese T2DM Patients Controlled Inadequately With Metformin Monotherapy.
• Active Temperature Management After Cardiac Surgery and Its Effect on Postoperative Cognitive Dysfunction
• Pharmacokinetics Centella Asiatica Product (CAP) in Mild Cognitive Impairment
• Tau Imaging With JNJ067
• A Longitudinal Evaluation of a Radiotracer for Use in Tau Tracking
• Modafinil to Prevent Postoperative Cognitive Decline
• The Effect of Donepezil in Radiotherapy-related Cognitive Impairment.
• Longitudinal Changes of [18F]PI-2620 Positron Emission Tomography in Subjects With Cognitively Normal, Mild Cognitive Impairment and Alzheimer's Disease
• Dexmedetomidine and Esmolol Early Post Operative Cognitive Dysfunction
• Efficacy and Safety of Ferrous Iron on the Prevention of Vascular Cognitive Impairment Among Patients With Cerebral Infarction/TIA (FAVORITE)
• Treating Hyperexcitability in AD With Levetiracetam
• MRI and PET Biomarkers for Cognitive Decline in Older Adults
• Study of Nasal Insulin to Fight Forgetfulness - Device Study
• Efficacy and Safety of Cytoflavin® Used in Elderly Patients for the Prevention of Cognitive Decline After Major Surgery
• Characterizing Clinical and Pharmacological Neuroimaging Biomarkers
• MBRP + Vortioxetine VS MBRP on Preventing Relapse in Chronic MA Users
• Study With Lu AF20513 in Patients With Mild Alzheimer's Disease (AD) or Mild Cognitive Impairment (MCI) Due to AD
• Vildagliptin in Older Adults With Diabetes and Mild Cognitive Impairment
• Clinical Trial of Efficacy and Safety of MMH-MAP in the Treatment of Mild Cognitive Impairment in Early Recovery Stage After Ischemic Stroke
• A Pilot of Methylphenidate in Mild Cognitive Impairment and Dementia Participants.
• Clinical Evaluation on the Therapeutic Effect of Acupuncture Treatment for Alzheimer's Disease
• Developing a Mobile Method to Measure THC-induced Impairment
• Modulating ApoE Signalling to Reduce Brain Inflammation, deLirium and postopErative Cognitive Dysfunction
• Effect of Intraoperative Dexmedetomidine on Early Postoperative Cognitive Dysfunction
• Triple Therapy Prevention of Recurrent Intracerebral Disease EveNts Trial (TRIDENT) Cognitive Sub-Study
• A Novel Therapeutic Target for Alzheimer's Disease in Men and Women 50-85 Years of Age.
• A Study to Evaluate the Safety and Efficacy of BIIB104 in Participants With Cognitive Impairment Associated With Schizophrenia (CIAS)
• Multiple Dose Trial of MK-4334 in Participants With Alzheimer's Clinical Syndrome (MK-4334-005)
• A Study to Assess the Safety of GRF6021 Infusions in Subjects With Parkinson's Disease and Cognitive Impairment
• A Pharmacodynamics, Safety, and Pharmacokinetics Study of THN201 Versus Donepezil in Healthy Male Volunteers
• Dose-response of Cannabis and Driving
• The LUCINDA Trial: LeUprolide Plus Cholinesterase Inhibition to Reduce Neurological Decline in Alzheimer's
• A Study of Aducanumab in Participants With Mild Cognitive Impairment Due to Alzheimer's Disease or With Mild Alzheimer's Disease Dementia to Evaluate the Safety of Continued Dosing in Participants With Asymptomatic Amyloid-Related Imaging Abnormalit
• Endothelial Injury Mechanism in Elderly Patients Undergoing Major Surgery
• Haloperidol for Delirium in Adult Critically Ill Patients
• 18F-PM-PBB3 PET Study in Tauopathy Including Alzheimer's Disease, Other Dementias and Normal Controls
• Modafinil's Effects on Cognition in Remitted MDD
• Inorganic Nitrate Supplementation on Cerebrovascular Aging and Arterial Stiffness Study
• Efficacy Study of Yi-Zhi-An-Shen Granules For Older Adults With Amnestic Mild Cognitive Impairment
• Neurocognitive Function Improvement After Switching From Efavirenz to Rilpivirine
• Multi-Center Development of a Novel Diagnostic Test for Alzheimer's Disease
• A Study to Assess the Safety and Efficacy of ASP4345 as Add-on Treatment for Cognitive Impairment in Subjects With Schizophrenia on Stable Doses of Antipsychotic Medication
• Brain and Gut Plasticity in Mild TBI Following Growth Hormone Therapy
• A Double-Blind, Placebo-Controlled Safety and Efficacy Study of NA-831
• Memantine for the Treatment of Cognitive Impairment in Systemic Lupus Erythematosus
• Effects of Amantadine on Postoperative Cognitive Dysfunction
• Synaptic Plasticity and Cognitive Function in RASopathies
• Study of AGB101 in Mild Cognitive Impairment Due to Alzheimer's Disease
• Preoperative Vitamin B12 and Folic Acid on POCD in Elderly Non-cardiac Surgical Patients
• NAD Therapy for Improving Memory and Brain Blood Flow in Older Adults With Mild Cognitive Impairment
• Dexmedetomidine to Reduce the Incidence of POCD After Open Cardiac Surgery
• Testing Ramipril to Prevent Memory Loss in People With Glioblastoma
• Taurine Supplementation on Cognitive Function in Patients With Diabetes
• A 12-weeks Study to Evaluate the Dietary Fiber and Probiotics Treatment in Prevention and Intervention of Weight-gain and Cognitive Impairment of Schizophrenia or Bipolar Disorder
• Tau PET in Imaging and Cognition: Healthy Adults From 55-90
• Aspirin as an add-on Treatment of Refractory Epilepsy in Tuberous Sclerosis Complex
• Phase 2 Study of BIIB092 in Participants With Early Alzheimer's Disease
• Effect of Memantine on Radiotherapy-related Cognitive Impairment
• Effects of Erythropoietin for Cognitive Side-effects of ECT
• The Effect of Intranasal Insulin Administration on Cognitive Function After Cardiac Surgery.
• Effects of Erythropoietin on Cognition and Neural Activity in Mood Disorders
• Memory and Antioxidants in Vascular Impairment Trial
• A Proof of Concept Study of the Prevention of Mild Cognitive Impairment and Eventual Alzheimer's Disease Using F18 Flutemetamol
• Remediation of Age-related Cognitive Decline: Vortioxetine and Cognitive Training
• Metformin Treatment on Cognitive Impairment of Schizophrenia Co-morbid Metabolic Syndrome
• Evaluation of the Safety and Efficacy of Ang-(1-7) to Enhance Cognitive Function in Participants Undergoing CABG
• Minocycline for Alcohol Use Disorder
• Deferiprone to Delay Dementia (The 3D Study)
• Choline Alphoscerate-Nimodipine in Vascular Cognitive Impairment
• Curcumin and Vascular and Cognitive Function in Patients With Chronic Kidney Disease
• Putative Cognitive Enhancer VU319
• Safety and Efficacy of ALZT-OP1a as Adjuvant Treatment in Subjects With Post-Ischemic Stroke Cognitive Impairment (PSCI)
• The Effect of Retrobulbar Block for Eye Surgery on Brain Oxygenation and Cognitive Functions in Elderly Patients
• IMProving Executive Function Study
• Cognitive Dysfunction in MDD Patients
• Low-Dose Ibuprofen in Improving Cognitive Impairment in Patients With Cancer
• Lithium As a Treatment to Prevent Impairment of Cognition in Elders
• Appropriate Compatibility of Propofol and Sevoflurane for Orthopaedic Surgery of Patients With MCI
• Using Less Neurotoxic Drugs in Patients With HAND (MARAND-X)
• To Study the Effect of Sevoflurane and Propofol V Sevoflurane and Dexmedetomidine on Postoperative Cognitive Dysfunction
• Effects of Huperzine A on Presbycusis(Δ,kHz, dB,MMSE, AD)
• The Role of Large Artery Plaque Imaging Features in Predicting Inflammation and Cognition
• Nicotinamide as an Early Alzheimer's Disease Treatment
• Impact of Anticoagulation Therapy on the Cognitive Decline and Dementia in Patients With Non-Valvular Atrial Fibrillation
• Subjects With Subjective Cognitive Decline: 18F-Florbetaben Positron Emission Tomography Study
• Flortaucipir 18F PET Imaging in BIOCARD Study
• Trial of Sirolimus for Cognitive Impairment in Sturge-Weber Syndrome
• Study to Evaluate the Effects of BPN14770 on Scopolamine-induced Cognitive Impairment in Healthy Volunteers
• A Study of LY3303560 in Participants With Mild Cognitive Impairment or Alzheimer's Disease
• Vitamin D Supplementation and Neurocognition
• Feasibility and Effects of Valaciclovir Treatment in Persons With Early Alzheimer's Disease
• The Efficacy of Butylphthalide Soft Capsules in Patents With VCIND
• Genomic Outcomes of Metformin
• Efficacy and Safety of 1612 Capsules in aMnestic Mild Cognitive Impairment
• Efficacy and Safety of Qinggongshoutao Bolus in aMnestic Mild Cognitive Impairment
• Effect of Methylphenidate on Cancer-related Cognitive Impairment
• CAMH - McMaster Collaborative Care Initiative For Mental Health Risk Factors In Dementia
• A Study to Evaluate the Effects of Basmisanil in Participants With Cognitive Impairment Associated With Schizophrenia (CIAS) Treated With Antipsychotics
• A Study of Health Care Use and Costs in Participants With Early Stage Alzheimer's Disease (AD)
• Effects of IV-Administered Ca-DTPA and Zn-DTPA To Treat Patients With Gadolinium Deposition Disease
• Comparison of Postoperative Outcome After Sevoflurane and Propofol Anaesthesia
• Early Diagnosis and Early Treatment of Alzheimer's Disease Based on Senile Plaque Imaging
• Minocycline Attenuate Postoperative Cognitive Dysfunction and Delirium
• Aftobetin-HCl and Fluorescence Detection Measured by Sapphire II to Determine the Number and Timing of Administrations
• Donepezil Attenuate Postoperative Cognitive Dysfunction
• Whether Dexmedetomidine Can Improve the Prognosis of Elderly Patients With Postoperative Cognitive Dysfunction
• Study for the Use of TKIs for Treatment of Cognitive Decline Due to Degenerative Dementias
• TAK-071 Scopolamine-Induced Cognitive Impairment Study
• Risk Reduction for Alzheimer's Disease
• An Open-Label Study Investigating MK-8931 in Participants With Mild and Moderate Hepatic Insufficiency (MK-8931-016)
• Comparison of Desflurane With Sevoflurane for School-age Children in Postoperative Cognitive Function
• Ketamine and Postoperative Cognitive Dysfunction
• A Pilot of the Feasibility of Using the Iron-Chelator Deferiprone on Mild Cognitive Impairment
• A Study To Evaluate The Safety And Efficacy Of PF-04958242 In Subjects With Cognitive Impairment Associated With Schizophrenia (CIAS)
• The Influence of Postoperative Analgesia on Systemic Inflammatory Response and POCD After Femoral Fractures Surgery
• Long-acting Exenatide and Cognitive Decline in Dysglycemic Patients
• Phase 3 Randomized Placebo Controlled Clinical Trial of Donepezil
• Comparison of PET Amyloid Imaging in Japanese and Western Subjects
• 11C-Acetate PET/CT Imaging As a Biomarker of Amyloid-Induced Neuroinflammation
• BI 425809 in Patients With Cognitive Impairment Due to Alzheimer's Disease.
• The Role of Ketamine in Preventing Cognitive Dysfunctions in Postoperative Period of Cardiac Surgery
• Implications for Management of PET Amyloid Classification Technology
• The Effects of Anaesthesia on Cerebral Oxygenation and Cognitive Function in Carotid Endarterectomy
• Study of TAK-071 in Healthy Participants and Participants With Mild Cognitive Impairment/Mild Alzheimer Disease and Relative Bioavailability (BA) and Food Effect of TAK-071 in Healthy Participants
• A Test of Neural Inertia in Humans With Xenon
• Cognitive Dysfunction Following Cardiac Surgery
• An fMRI Study of Jianpi Yishen Huatan Granules for Cognitive Impairment After Acute Cerebral Infarction
• Memory Improvement Through Nicotine Dosing (MIND) Study
• Dosage and Efficacy of Probucol-induced apoE to Negate Cognitive Deterioration
• Randomized Trial of Low-dose Naproxen in Cognitively Intact Persons at Risk of Alzheimer's Dementia
• Dexmedetomidine Use in ICU Sedation and Postoperative Recovery in Elderly Patients and Post-cardiac Surgery
• Adderall XR and Cognitive Impairment in MS
• Quality Improvement and Practice Based Research in Neurology Using the EMR
• Safety Study of Sargramostim in Treating Patients With Mild Cognitive Impairment Due to Alzheimer's Disease
• Impact of Anesthesia Maintenance Methods on Incidence of Postoperative Delirium
• [18F]THK-5351 Positron Emission Computed Tomography Study of Normal, Mild Cognitive Impairment, Alzheimer's Disease and Other Neurodegenerative Disease
• A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity
• Candesartan's Effects on Alzheimer's Disease And Related Biomarkers
• The Study of Jian Pi Yi Shen Hua Tan Granules in Cognitive Impairment After Acute Cerebral Infarction
• A Study of LY2599666 in Healthy Participants and Participants With Mild Cognitive Impairment or Alzheimer's Disease (AD)
• Evaluation of Lithium as a Glycogen-Synthase-Kinase-3 (GSK-3) Inhibitor in Mild Cognitive Impairment
• Phenytoin for Memory Impairment Secondary to Megestrol
• The Use of Duloxetine for Cognition Improvement in Individuals With Mild Cognitive Impairment
• Safety, Tolerability and the Effects on Cerebrospinal Fluid Spectrin Breakdown Product-145 Levels of ABT-957 in Subjects With Mild Alzheimer's Disease and Mild Cognitive Impairment
• Phase II Trial of Tesamorelin for Cognition in Aging HIV-Infected Persons
• Ascending Dose Study of CT1812 in Healthy Volunteers
• [18F]MK-6240 Positron Emission Tomography (PET) Tracer First-in-Human Validation Study (MK-6240-001)
• The Impact of Ketamine on Postoperative Cognitive Dysfunction, Delirium, and Renal Dysfunction
• The Effect of Growth Hormone Releasing Hormone on Cognitive Function in Individuals With Mild Cognitive Impairment
• The Effect of Nimodipine on the Postoperative Cognitive Dysfunction
• Mirabegron in Parkinson Disease and Impaired Cognition
• Docosahexaenoic Acid (DHA) To Prevent Development of Cognitive Dysfunction Due to Chemotherapy
• Treatment of Cognitive and Negative Symptoms in Schizophrenia With N-acetylcysteine
• Intranasal Glulisine in Amnestic Mild Cognitive Impairment and Probable Mild Alzheimer's Disease
• BDPP Treatment for Mild Cognitive Impairment (MCI) and Prediabetes or Type 2 Diabetes Mellitus (T2DM)
• Improving Beta-2 Adrenergic Signaling in Alzheimer's Disease
• A Trial of Cilostazol in Patients With Mild Cognitive Impairment (COMCID)
• Study of Nasal Insulin to Fight Forgetfulness - Short-Acting Insulin Aspart
• Acupuncture Prevents Chemobrain in Breast Cancer Patients
• Target Hemodynamics and Brain Injury During General Anesthesia in the Elderly
• Clinical Pharmacology of p38 MAP Kinase Inhibitor, VX-745, in Mild Cognitive Impairment Due to Alzheimer's Disease (AD) or Mild AD
• A PET Study of the Effects of p38 MAP Kinase Inhibitor, VX-745, on Amyloid Plaque Load in Alzheimer's Disease (AD)
• Sugammadex and Cognitive Function
• Insulin Resistance and Mild Cognitive Impairment (IRMCI) Study
• Anesthesia Depth Increases the Degree of Postoperative Dementia, Delirium, and Cognitive Dysfunction
• Effects of Methylene Blue in Healthy Aging, Mild Cognitive Impairment and Alzheimer's Disease
• Thermoregulation and Cognition During Cool Ambient Exposure in Tetraplegia
• Investigating the Clinical Consequences of Flutemetamol-PET-scanning
• BI 409306 in Patients With Cognitive Impairment Due to Alzheimer's Disease.
• A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity Pilot
• Ritalin, Memory and Attention in MCI: a Behaviour-EEG Study
• Dose-Finding Study To Evaluate Safety, Tolerability, and Efficacy of E2609 in Participants With Mild Cognitive Impairment Due to Alzheimer's Disease (Prodromal Alzheimer's Disease) and Mild to Moderate Dementia Due to Alzheimer's Disease
• Amyloid Plaque Deposition in Chemotherapy-Induced Cognitive Impairment
• Nicotinic Treatment of Post-Chemotherapy Subjective Cognitive Impairment: A Pilot Study
• Effect of Subanesthetic Dose of Ketamine Combined With Propofol on Cognitive Function in Depressive Patients Undergoing Electroconvulsive Therapy
• Long Term Postoperative Cognitive Dysfunction in the Elderly Patients
• AD-4833/TOMM40_303 Extension Study of the Safety and Efficacy of Pioglitazone to Slow Cognitive Decline in Participants With Mild Cognitive Impairment Due to Alzheimer Disease
• Efficacy of Vortioxetine on Cognitive Dysfunction in Working Patients With Major Depressive Disorder
• Efficacy of Vortioxetine on Cognitive Dysfunction in Patients With Partial or Full Remission of Major Depressive Disorder
• Move for Your Mind - Pilot Trial
• Amyloid and Tauopathy PET Imaging in Acute and Chronic Traumatic Brain Injury
• An Open-Label Trial of Memantine for Cognitive Impairment in Patients With Post-Traumatic Stress Disorder
• A Study of Fesoterodine and Oxybutynin on Cognitive Function in Mild Cognitive Impairment
• NMDA-enhancing Agent for the Treatment of Mild Cognitive Impairment
• Galantamine and Memantine Combination for Cognitive Impairments in Schizophrenia
• Extension Study of Intrathecal Enzyme Replacement for Cognitive Decline in MPS I
• Aprepitant to Mitigate Opioids' Cognitive Side Effects
• Effects of Different Doses of Dexmedetomidine on Postoperative Cognitive Dysfunction in Elderly Hypertensive Patients
• Allopregnanolone for Mild Cognitive Impairment Due to Alzheimer's Disease or Mild AD
• Ketamine Prevent POCD
• Preventing Post-Operative Delirium in Patients Undergoing a Pneumonectomy, Esophagectomy or Thoracotomy
• Citocoline for Treatment of FXTAS
• Effect of Vitamin D on Cognitive Decline of Patients With Memory Complaint
• The Effects of Methylphenidate on the Cognitive Function of Older People With Mild Cognitive Impairment
• Methylphenidate Treatment of Attention Deficits in Epilepsy
• Computerized Exercise Training for Cognitive Remediation in Adults With Multiple Sclerosis Treated With Gilenya
• Effects of Dexmedetomidine on Postoperative Cognitive Dysfunction During One-lung Ventilation in Elder Patients
• Lipoic Acid and Omega-3 Fatty Acids for Cognitive Impairment in Multiple Sclerosis
• Vascular Mechanisms for the Effects of Loss of Ovarian Hormone Function on Cognition in Women
• Dexamethasone and Postoperative Delirium
• Curcumin as a Novel Treatment to Improve Cognitive Dysfunction in Schizophrenia
• Symptomatic Treatment of Vascular Cognitive Impairment
• Neuroprotection With Dexmedetomidine in Patients Undergoing Elective Cardiac or Abdominal Surgery (Neuprodex)
• A Randomized, Double-blind, Placebo-controlled Study to Assess Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Pharmacodynamic Response of Repeated Intravenous Infusions of BAN2401 in Subjects With Mild Cognitive Impairment Due to Alzhei
• The Efficacy And Cognitive Impairment Of Modified Electroconvulsive Therapy
• PET Imaging of the Translocator Proteine Ligands (TSPO) With [18 F] DPA-714 Biomarker of NeuroInflammation in Cognitive Decline (NIDECO)
• Remifentanil/Sufentanil for CABG+/-AVR Evaluated by Recovery, Cognitive Function, Haemodynamics and Biochemical Markers.
• Reversal of General Anesthesia With Methylphenidate
• Ketamine and Changes of the Short Portable Mental Status Questionnaire
• Switching From Efavirenz/Atripla to Rilpivirine Among Patients With Neurocognitive or Neuropsychological Side Effects
• Cognitive Impairment Related to Atrial Fibrillation Prevention Trial
• Markers of Alzheimers Disease and Cognitive Outcomes After Perioperative Care
• LDX for the Treatment of Cognitive Functioning Issues in Women Post-Oophorectomy
• CAndesartan vs LIsinopril Effects on the BRain
• Evaluation Prospectively the Level of Reduction in Cognitive Functions of Cancer Patients Who Are on Active Oncology Treatments and Use Cannabis. The Second Goal is to Identify High-risk Groups for Cognitive Impairment Due to Cannabis Use.
• Targeting Circadian and Cognitive Dysfunction in Bipolar Disorder With Modafinil
• Complementary Neurosteroid Intervention in Gulf War Illnesses (GWVI)
• n-3 PUFA for Vascular Cognitive Aging
• Efficacy and Safety Trial of Verubecestat (MK-8931) in Participants With Prodromal Alzheimer's Disease (MK-8931-019)
• Olfactory Deficits and Donepezil Treatment in Cognitively Impaired Elderly
• Postoperative Recovery in Elderly Patients Undergoing Hip Hemi-arthroplasty
• Biomarker Qualification for Risk of Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease (AD) and Safety and Efficacy Evaluation of Pioglitazone in Delaying Its Onset
• Reconstructing Consciousness and Cognition
• Pharmacokinetics and Pharmacodynamics (PK/PD) of CEP-26401 in Healthy Subjects
• Brain Aging and Treatment Response in Geriatric Depression
• Characterizing and Predicting Drug Effects on Cognition
• N-acetylcysteine (NAC) for Improving Cognitive Dysfunction in Schizophrenia
• Memantine Plus Es-citalopram in Elderly Depressed Patients With Cognitive Impairment
• The Efficacy and Safety of a Selective Estrogen Receptor Beta Agonist (LY500307) for Negative Symptoms and Cognitive Impairment Associated With Schizophrenia
• Efficacy and Safety of Cilostazol in Patients of Vascular Cognitive Impairment-no Dementia (VCIND)
• NEURoaid II (MLC 901) Assessment in Cognitively Impaired Not Demented Subjects
• Olfactory Deficits in MCI as Predictor of Improved Cognition on Donepezil
• Body Temperature in Persons With Tetraplegia When Exposed to Cold
• Phosphodiesterase (PDE) Inhibitors Effect on Cognitive Deficits Associated to Schizophrenia
• Beta-Amyloid Imaging With [18F]NAV4694 Positron Emission Tomography (PET) in Predicting Progression to Alzheimer's Disease (AD) in Subjects With Mild Cognitive Impairment (MCI)
• Curcumin and Yoga Therapy for Those at Risk for Alzheimer's Disease
• Comparison of Intravenous Anesthetics to Volatile Anesthetics on Postoperative Cognitive Dysfunction
• Nicotine Treatment of Cognitive Decline in Down Syndrome
• The Study of Nasal Insulin in the Fight Against Forgetfulness (SNIFF)
• A Study To Examine The Effects Of PF-04958242 On Ketamine-Induced Cognitive Impairment In Healthy Volunteers
• The MENDS2 Study, Maximizing the Efficacy of Sedation and Reducing Neurological Dysfunction and Mortality in Septic Patients With Acute Respiratory Failure
• Atomoxetine Treatment for Cognitive Impairment in Parkinson's Disease (ATM-Cog)
• Arterial Spin Labeling (ASL) MRI for Cognitive Decline
• Evaluation of Effects of Multiple Dose Regimens of CHF 5074 on Potential Biomarkers of Neurodegeneration in Subjects With Mild Cognitive Impairment
• Study of EVP-6124 (Alpha-7 nAChR) as an Adjunctive Pro-Cognitive Treatment in Schizophrenia Subjects on Chronic Stable Atypical Antipsychotic Therapy
• A 26-Week Extension Study of EVP-6124 (Alpha-7 nAChR) as an Adjunctive Pro-Cognitive Treatment in Schizophrenia Subjects on Chronic Stable Atypical Antipsychotic Therapy
• Study of EVP-6124 (Alpha-7 nAChR) as an Adjunctive Pro-Cognitive Treatment in Schizophrenia Subjects on Chronic Stable Atypical Antipsychotic Therapy
• Effect of Depth of Total Intravenous Anesthesia Using Propofol on Postoperative Cognitive Dysfunction
• DIetary Supplements, Executive funcTions and Vitamin D (DIET-D)
• Effectiveness of Florbetapir (18F) PET Imaging in Changing Patient Management and the Relationship Between Scan Status and Cognitive Decline
• Optimization of Desflurane in Elderly Patients
• Mild Cognitive Impairment in Men Following Androgen Deprivation
• A Phase 2 Study to Evaluate ABT-126 for the Treatment of Cognitive Deficits in Schizophrenia
• Effectiveness of an Electronic Training Program for Orienting and Interpreting [18F]Flutemetamol Positron Emission Tomography (PET) Images
• Rivastigmine Patch in Veterans With Cognitive Impairment Following TBI
• A Large Randomized Trial of Vitamin D, Omega-3 Fatty Acids and Cognitive Decline
• Adderall XR and Processing Speed in Multiple Sclerosis (MS)
• A Phase II Trial of Florbetapir (18F) Positron Emission Tomography (PET) Imaging in Japan of Healthy Volunteers, Patients With Mild Cognitive Impairment (MCI) and Patients With Alzheimer's Disease (AD)
• Safety, Tolerability, Pharmacokinetics of EVP-0962 and Effects of EVP-0962 on Cerebral Spinal Fluid Amyloid Concentrations in Healthy Subjects and in Subjects With Mild Cognitive Impairment or Early Alzheimer's Disease
• Combination Treatment Study for Memory Impairment and Depression
• A Study to Evaluate ABT-126 for the Treatment of Cognitive Deficits in Schizophrenia
• Efficacy of Pulsatile IV Insulin on Cognition and Amyloid Burden in Patients With Alzheimer's Disease
• Fluoxetine Prevention Trial
• Effects of Brain Beta-Amyloid on Postoperative Cognition
• Evaluation of Safety & Tolerability of Multiple Dose Regimens of CHF 5074 and Exploration of Effects on Potential Markers of Clinical Efficacy in Patients With Mild Cognitive Impairment - Prolonged Open Label Extension Phase
• Study of Exelon Transdermal Patch in Amnestic Mild Cognitive Impairment Patients
• Evaluation of E2609 in Subjects With Mild Cognitive Impairment or Mild Dementia Due to Alzheimer's Disease (Study: E2609-A001-101 Amendment 02)
• NMDA-enhancing Agent for Treatment of Mild Cognitive Impairment and Mild Alzheimer's Disease
• Effects of Antimuscarinics on Cognition in Spinal Cord Injury
• Study of Nasal Insulin to Fight Forgetfulness - Long-acting Insulin Detemir - 120 Days (SL120)
• Efficacy and Safety of Actovegin in Post-stroke Cognitive Impairment (PSCI)
• Efficacy of Lu AA21004 on Cognitive Dysfunction in Major Depressive Disorder
• Study of LY2886721 in Mild Cognitive Impairment Due to Alzheimer's Disease or Mild Alzheimer's Disease
• Cardiac Surgery Neuroprotection Study in Elders
• Evaluation of Web-based Training to Educate Physicians in the Methods of Interpreting Florbetapir-PET Scans
• A Study of the Safety and Tolerability of AZD5213 Effect on Sleep for Patients With Alzheimer's/Cognitive Impairment
• Study of Nasal Insulin to Fight Forgetfulness - Long-acting Insulin Detemir - 21 Days
• Effects of Atomoxetine in Mild Cognitive Impairment
• Mild Cognitive Impairment in Parkinson's Disease
• Clinical Evaluation of Florbetapir F 18 (18F-AV-45)
• Cognitive Rehabilitation and Galantamine for Post Stroke Cognitive Impairment
• Extension Study of HGT-HIT-045 Evaluating Long-Term Safety and Clinical Outcomes of Idursulfase-IT in Conjunction With Elaprase in Pediatric Participants With Hunter Syndrome and Cognitive Impairment
• A Double Blind Placebo Controlled Trial Evaluating Rasagiline Effects on Cognition in Parkinson's Disease Patients With Mild Cognitive Impairment Receiving Dopaminergic Therapy
• A Double-blind, Placebo-controlled Trial of Donepezil Adjunctive Treatment for Cognitive Impairment in Schizophrenia
• Efficacy, Safety, and Tolerability of TC-5619 as Augmentation Therapy to Improve Negative Symptoms and Cognition in Outpatients With Schizophrenia
• Safety Study of HPP854 in Subjects With Mild Cognitive Impairment or a Diagnosis of Mild Alzheimer's Disease
• Study of Donepezil in Female Breast Cancer Survivors With Cognitive Dysfunction
• Clinical Testing of a D1 Agonist for Cognitive Enhancement in Schizotypal Personality Disorder
• Minocycline in Patients With Alzheimer's Disease
• DaTSCAN Imaging in Aging and Neurodegenerative Disease
• Efficacy and Safety Study of Shenwu Capsule
• A 3 Year Study to Evaluate the Safety and Efficacy of Low Dose Ladostigil in Patients With Mild Cognitive Impairment
• Efficacy Study of Vortioxetine on Cognitive Dysfunction in Adult Patients With Major Depressive Disorder
• Evaluation of Safety & Tolerability of Multiple Dose Regimens of CHF 5074 and Exploration of Effects on Potential Markers of Clinical Efficacy in Patients With Mild Cognitive Impairment - Open Label Extension (CT04 OLEP)
• Potential of Florbetapir F 18 PET to Inform Clinical Diagnosis and Management of Patients With Progressive Cognitive Decline
• Egcg, a dyrk1a Inhibitor as Therapeutic Tool for Reversing Cognitive Deficits in Down Syndrome Individuals.
• 18-Month Study of Memory Effects of Curcumin
• Changes in Cerebral Function in Treatment Naive HIV-1 Infected Subjects Commencing Either Boosted Atazanavir With Truvada or Boosted Darunavir With Maraviroc and Kivexa
• The Efficacy of Gliatiline® on Post-stroke Patients With Vascular Cognitive Impairment no Dementia
• Safety and Efficacy Study of Ladostigil in Mild to Moderate Probable Alzheimer's Disease
• Efficacy and Safety of Two Pharmacologic Strategies on Neurocognitive Impairment in HIV Infection. The TRIANT-TE Study
• Add On Treatment for Cognitive Deficits in Schizophrenia
• Antiglucocorticoid Therapy for Cognitive Impairment in Late-life Anxiety Disorders
• Dexamethasone for the Prevention of Postoperative Cognitive Dysfunction
• Alzheimer's Disease and Related Disorders
• Effect of Varenicline on Tobacco Addiction and on Abstinence-induced Cognitive Impairment
• Study of Intravenous Immunoglobulin in Amnestic Mild Cognitive Impairment
• Effects of Eltoprazine on Cognitive Impairment Associated With Schizophrenia (CIAS) in Adults
• Non-cancer Pain and Cognitive Impairment: A Disabling Relationship
• A Pilot Clinical Trial of Exendin-4 in Alzheimer's Disease
• The Influence of GINkGo Biloba on the Pharmacokinetics of the UGT Substrate raltEgraviR (GINGER)
• Phase II Study for Amyloid Binding Imaging Study of [18F]AV-45 in Patients With Mild Cognitive Impairment, Alzheimer's Disease and Healthy Volunteers
• Efficacy and Safety Study of Nimodipine to Prevent Mild Cognitive Impairment After Acute Ischemic Strokes
• A Trial to Explore the Potential Benefit of Safinamide on Cognitive Impairment Associated With Parkinson's Disease
• The Modifying the Impact of ICU-Associated Neurological Dysfunction-USA (MIND-USA) Study
• Effects of Doxycycline on Persistent Symptoms Post-neuroborreliosis
• Statin Therapy To Limit Cognitive Dysfunction After Cardiac Surgery
• Placebo-Controlled Crossover Study to Evaluate Donepezil and MK-3134 for Reversal of Cognitive Impairment Associated With Scopolamine Administration (3134-005)(COMPLETED)
• Pioglitazone Hydrochloride in Preventing Radiation-Induced Cognitive Dysfunction in Treating Patients With Brain Tumors
• Florbetaben (BAY94-9172) PET (Positron Emission Tomography) Imaging in MCI (Mild Cognitive Impairment) Patients
• The Effect of Physostigmine on Cognitive Functioning in the Immediate Period After Sedation for Colonoscopy
• A Study of the Effect of RO4917838 on Biomarker Measures of Cognitive Dysfunction in Participants With Schizophrenia and Schizoaffective Disorder
• Safety and Efficacy Study for Cognitive Deficits in Adult Subjects With Schizophrenia
• Efficacy and Safety Study for Cognitive Deficits in Adult Subjects With Schizophrenia
• Study of the Pharmacokinetics and Pharmacodynamics of POSIPHEN® in Subjects With Amnestic Mild Cognitive Impairment
• Efficacy and Safety of Lisdexamfetamine Dimesylate in Adults With Chronic Fatigue Syndrome
• Disease-modifying Properties of Lithium in the Neurobiology of Alzheimer's Disease
• Treximet for Prevention of Post Traumatic Headache Associated With Cognitive Dysfunction
• Effect of Ginkgo Biloba Special Extract LI 1370 on Dual-tasking in Patients With MCI
• Levetiracetam and Memory Function in Amnestic Mild Cognitive Impairment (MCI)
• Assess the Prognostic Usefulness of Flutemetamol (18F) Injection for Identifying Subjects With Amnestic Mild Cognitive Impairment Who Will Convert to Clinically Probable Alzheimer's Disease
• Oxytocin or Galantamine Versus Placebo for the Treatment of Negative Symptoms and Cognitive Impairments in Schizophrenia
• TC-5619 as Augmentation Therapy to Improve Cognition in Outpatients With Cognitive Dysfunction in Schizophrenia
• Gabapentin Treatment of Cannabis Dependence
• Lidocaine For Neuroprotection During Cardiac Surgery
• Guanfacine Treatment for Prefrontal Cognitive Dysfunction in Elderly Subjects
• Donepezil and the Risk of Falls in Seniors With Cognitive Impairment
• A 28-Week Open Label Extension Study Evaluating Safety and Tolerability of Donepezil Hydrochloride in Subjects With Mild Cognitive Impairment
• MemoryXL Effects on Mild Cognitive Impairment Patients
• Rivastigmine in Multiple Sclerosis Patients With Cognitive Impairment
• A PET Brain Imaging Study of mGluR5 in Subjects With Neuropsychiatric Conditions
• Observational Study of Cognitive Outcomes for Subjects Who Have Had Prior PET Amyloid Imaging With Florbetapir F 18 (18F-AV-45)
• Minocycline for HIV+ Cognitive Impairment in Uganda
• A Study of Intrathecal Enzyme Therapy for Cognitive Decline in MPS I
• Treatment of Cognitive Impairment in Men With Schizophrenia (MK5757-005)(COMPLETED)
• Trial of Simvastatin in Amnestic Mild Cognitive Impairment (MCI) Patients
• Cognitive Impairment in Patients With Heart Failure
• Rivastigmine in the Treatment of Postoperative Delirium: a Pilot Clinical Trial
• Effect of EGb761® on Brain Glucose Metabolism in Three Groups of Elderly Defined by Cognitive Functions
• Varenicline for Cognitive Deficits and Cigarette Smoking in Schizophrenia - Efficacy and Predictors
• Brain Uptake and Safety With Probable Alzheimer's Disease, Amnestic Mild Cognitive Impairment and Healthy Volunteers
• Septic Encephalopathy and Late Cognitive Dysfunction
• Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (Aricept) In The Treatment Of The Cognitive Dysfunction Exhibited By Children With Down Syndrome, Aged 11 To 17
• Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (Aricept) In The Treatment Of The Cognitive Dysfunction Exhibited By Children With Down Syndrome, Aged 6 To 10
• Quetiapine XR for Cognitive and Functional Disability in Clinically Stable Patients With Bipolar Disorder
• A 6-Week Multicenter Trial Of Varenicline Tartrate For Cognitive Impairment In Subjects With Schizophrenia
• Pioglitazone Or Exercise to Treat Mild Cognitive Impairment (MCI)
• A Phase II Trial of 18F-AV-45 Positron Emission Tomography (PET) Imaging in Healthy Volunteers, Patients With Mild Cognitive Impairment (MCI) and Patients With Alzheimer's Disease (AD)
• The Effects of Rasagiline on Cognitive Deficits Associated With Parkinson's Disease
• Evaluating The Safety Of Donepezil Hydrochloride (Aricept) For Up To 1 Year In The Treatment Of The Cognitive Dysfunction Exhibited By Children With Down Syndrome - Follow-Up To A 10-Week, Double-Blind, Placebo-Controlled Trial
• Omega-3 Fatty Acids and/or Multi-domain Intervention in the Prevention of Age-related Cognitive Decline
• RIVastigmine In Vascular cognitivE Impairment
• Memantine and Cognitive Dysfunction in Bipolar Disorder
• Metformin in Amnestic Mild Cognitive Impairment
• N-acetylcysteine and NMDA Antagonist Interactions
• GABA-glutamate Interactions and Psychosis
• Placebo Controlled Study of Atomoxetine in the Treatment of Mild to Moderate Cognitive Difficulties in Menopausal Women
• The Antihypertensives and Vascular, Endothelial and Cognitive Function Trial
• Study to Evaluate the Safety and Efficacy of MEM 3454 as Adjunctive Treatment in Combination With a Preexisting Antipsychotic in Patients With Cognitive Impairment Associated With Schizophrenia
• Cannabidiol Treatment of Cognitive Dysfunction in Schizophrenia
• Memantine and Cognitive Dysfunction in Bipolar Disorder
• Effect of AQW051 in Patients With Memory Impairment
• Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (HCl) (Aricept) In Treating Cognitive Dysfunction Exhibited By Children With Down Syndrome
• A Study Of Adjunctive Treatment Of Cognitive Deficits In Schizophrenia
• Efficacy and Safety of Piracetam Taken for 12 Months in Subjects Suffering From Mild Cognitive Impairment (MCI)
• Perioperative Cognitive Function - Dexmedetomidine and Cognitive Reserve
• The Effect of Melatonin on Cognitive Function in Patients Diagnosed With Mild Cognitive Impairment
• Hormone and Information Processing Study
• A Study of C105 on Cognitive Dysfunction in Persons With Multiple Sclerosis
• Elder Surgery - Functional Recovery Following Beta Blockade
• Comparative Efficacy, Safety, and Tolerability of Rivastigmine 10 and 15 cm^2 Patch in Patients With Alzheimer's Disease (AD) Showing Cognitive Decline
• MK0249 for the Treatment of Cognitive Impairment in Patients With Schizophrenia (0249-016)
• Efficacy and Safety of Armodafinil as Adjunctive Therapy in Schizophrenic Adults With Cognitive Deficits
• Naratriptan for the Treatment of Post Traumatic Headache Associated With Cognitive Dysfunction
• MK0557 for the Treatment of Cognitive Impairment in Patients With Schizophrenia (0557-027)
• An Imaging Study to Investigate the Distribution of GSK239512 in the Brain.
• Guanfacine Adjunctive Treatment to Atypical Antipsychotics for Cognitive Dysfunction in Schizophrenia
• Galantamine for Cognitive Deficits in Schizophrenia
• Cognitive Protection - Dexmedetomidine and Cognitive Reserve
• Silent Cerebrovascular Lesion and Cognitive Decline Prevention by Cholesterol Lowering in Elderly AF Patients
• Efficacy and Safety of Ginkgo Biloba Extract in Mild Cognitive Impairment and Cerebrovascular Insufficiency
• Cognitive Impairment Following Sedation for Colonoscopy With Propofol, Midazolam and Fentanyl Combinations
• SNIFF 120: Study of Nasal Insulin to Fight Forgetfulness (120 Days)
• Modafinil for Treatment of Cognitive Dysfunction in Schizophrenia
• Safety, Tolerability and Efficacy Study to Evaluate Subjects With Mild Cognitive Impairment
• Study to Evaluate Safety, Tolerability, and Effect of AL208 on Mild Cognitive Impairment Following Coronary Artery Bypass Graft Surgery
• Dopaminergic Enhancement of Learning and Memory in Healthy Adults and Patients With Dementia/Mild Cognitive Impairment
• Trial of Memantine for Cognitive Impairment in Multiple Sclerosis
• Gastrodin Prevents Cognitive Decline Related to Cardiopulmonary Bypass
• Memantine for Treatment of Cognitive Impairment in Patients With Parkinson's Disease and Dementia
• The Evaluation of the Efficacy and Safety of Donepezil Hydrochloride in Subjects With Mild Cognitive Impairment (MCI)
• Study on the Effectiveness of EGb 761® vs Placebo Used for Cognitive Impairment in Patients With Multiple Sclerosis
• The Impact of Renin-angiotensin System on Brain Activation During Hypoglycaemia in Healthy Men, a PET Study
• SMART: Somatotrophics, Memory, and Aging Research Trial
• Rosiglitazone Effects on Cognition for Adults in Later Life
• A Follow-up Study to Assess Safety and Tolerability of Galantamine Treatment in Individuals With Mild Cognitive Impairment
• D-Serine Treatment of Negative Symptoms and Cognitive Deficits in Schizophrenia
• A Study to Evaluate the Efficacy and Safety of Galantamine in Patients With Mild Cognitive Impairment
• A Study to Evaluate the Efficacy and Safety of Galantamine in Patients With Mild Cognitive Impairment
• An Extension Study Evaluating the Efficacy and Safety of Rivastigmine in Patients With Traumatic Brain Injury (TBI) With Persistent Cognitive Deficits
• Methylene Blue for Cognitive Dysfunction in Bipolar Disorder
• The CAMPUS Project: Cholinergic Augmentation of Cognitive Deficits in Schizophrenia
• Efficacy and Safety of S18986 in the Treatment of Mild Cognitive Impairment Patients
• Effective Adjunctive Use of Pergolide for Cognitive Impairment and Negative Symptoms in Schizophrenia
• A Double-Blind, Placebo-Controlled Study of Galantamine to Improve Cognitive Dysfunction in Bipolar Disorder
• Donepezil in the Prevention of Post-Operative Cognitive Decline
• Efficacy Study of Galantamine for Cognitive Impairments in Schizophrenia
• Efficacy and Safety of Rivastigmine in Patients With Traumatic Brain Injury and Cognitive Impairment
• Atomoxetine as an Adjunct to Novel Antipsychotic Medication in the Treatment of Cognitive Deficits of Schizophrenia
• Memantine for the Treatment of Cognitive Dysfunction and Negative Symptoms in Patients With Chronic Schizophrenia
• Memantine for the Prevention of Cognitive Dysfunction and Negative Symptoms in Patients With Acute Schizophrenia
• Efficacy and Safety of Rivastigmine in Patients With Mild Cognitive Impairment
• Angiotensin II Receptor Blockers (ARB) and ACE Inhibitors (ACEI) on Silent Brain Infarction and Cognitive Decline
• The Efficacy, Safety, And Tolerability Of Donepezil HCl (E2020) In Patients With CADASIL Who Have Cognitive Impairment
• Nicotine Treatment of Mild Cognitive Impairment (MCI)
• Donepezil HCl & Cognitive Deficits in Autism
• Efficacy And Safety Of CX516 In Elderly Participants With Mild Cognitive Impairment.
• Prevention of Cognitive Decline in Alzheimer's Disease by Ingested Interferon Alpha
• Preventing Cognitive Decline With Alternative Therapies
• Phase II Study of the Efficacy of Peptide T in HIV-Positive Individuals With Cognitive Impairment.
• Memory Impairment Study (Mild Cognitive Impairment Study)