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Clinical Trials for Heart Failure

• Effects of Levosimendan on Cardiac Function After TAVR in Patients With Heart Failure
• A Study to Learn How Safe Starting Vericiguat at a Dose of 5 Milligrams is in Participants With Chronic Heart Failure With Reduced Ejection Fraction
• Immediate Release Versus Extended Release Torsemide After Salty Meal
• Pharmacokinetics and Pharmacodynamics of Subcutaneous vs Intravenous Furosemide in Healthy Volunteers
• Optimal Diuretic Therapies for Acute Heart Failure With Volume Overload
• A Safety Study of Sacubitril/Valsartan in Japanese Pediatric Patients With Heart Failure Due to Systemic Left Ventricle Systolic Dysfunction Who Have Completed CLCZ696B2319E1 Study
• SGLT2 Inhibitors in Patients With ADHF During Ventilator Weaning
• A Proof of Concept and Dose-finding Study of XXB750 in Patients With Heart Failure
• Withdrawal of Treatment for Heart Failure Patients With Recovery From Tachycardia-induced Cardiomyopathy
• Clinical Efficacy of Early Left Bundle Branch Pacing for Cardiac Resynchronization Therapy
• Catheter Ablation in Atrial Fibrillation Patients With HFpEF (STABLE-SR IV Trial)
• Effect of Vasopressin on Kidney and Cardiac Function in Septic Shock
• Study to Evaluate Safety, Tolerability and Drug Levels of BMS-986435/MYK-224 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)
• Therapy to Maintain Remission in Dilated Cardiomyopathy
• The COLchicine HEART Failure PRESERVED Trial (COLHEART-PRESERVED)
• The Effect of Addition of Metformin to SGLT2 In Diabetic Patients With Heart Failure With Preserved Ejection Fraction
• Thoracic Epidural Anesthesia Reduces Mortality and Rehospitalization for Patients With Heart Failure With Reduced Ejection Fraction
• Sodium-glucose Transport 2 Inhibitors (SGLT2i) in HFrEF Patients
• The Effects of IL-1 Blockade on Inotrope Sensitivity in Patients With Heart Failure (AID-HEART)
• Effects of SGLT2 Inhibitors in Pre-heart Failure Populations With Hypertension
• A Study of Ultra High Dose Diuretics to Treat Heart Failure
• Heart Failure Polypill at a Safety Net Hospital
• Enavogliflozin Outcome Trial in Functional Tricuspid Regurgitation
• Acute Effects of Furosemide on Hemodynamics and Pulmonary Congestion in Acute Decompensated Heart Failure.
• A Phase IV, Two-part, Open-label Study Assessing the Pharmacokinetics, Safety and Pharmacodynamics of Spironolactone Oral Suspension in Pediatric Patients
• Evaluate Efficacy, Safety and Tolerability of JTT-861 in Subjects With Heart Failure With Reduced Ejection Fraction
• Clinical Outcomes of Dapagliflozin in Acute Heart Failure With Reduced Ejection Fraction (CODA-HFrEF)
• A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
• The Effects of Ferric Derisomaltose in Patients With Acute Heart Failure and Iron Deficiency on Exercise Capacity and Quality of Life
• Initiation of ARNi and SGLT2i in Patients With HFrEF
• Diuretic Strategies in Acute Heart Failure Patients at High Risk for Diuretic Resistance
• Reverse Remodeling Effects of CDR132L in Patients With Heart Failure With Mildly Reduced or Preserved Ejection Fraction and Cardiac Hypertrophy
• A Study to Assess the Effect of Danicamtiv on the Drug Levels of Midazolam in Participants With Stable Heart Failure
• Effect of Short-term Prednisone Therapy on C-reactive Protein in Patients With Acute Heart Failure
• The Heart Failure Diuresis Efficacy Comparison (DEA-HF) Study
• Allopurinol Improves Heart Function in African Americans With Resistant Hypertension
• A Randomised, Controlled Trial of a Low-energy Diet for Improving Functional Status in Heart Failure With PRESERVED Ejection Fraction Preserved Ejection Fraction
• Sacubitril/Valsartan Versus Valsartan in Heart Failure
• COLchicine and Thiamine in Heart Failure Due to Ischemic Heart Disease
• The Relationship Between XinKang-I and Chronic Heart Failure
• The Effect of Addition of Metformin In Obese Non- Diabetic Patients With Heart Failure With Preserved Ejection Fraction
• Combination Diuretic Therapy for Acute Decompensated Heart Failure
• Pioglitazone on Heart Failure in Type-2 Diabetes Mellitus Participants
• A Trial to Evaluate the Safety and Efficacy of Pulmonary Artery Denervation for the Treatment of Pulmonary Hypertension Associated With Left Heart Disease
• Effects of IV Iron Replacement on Exercise Capacity in Individuals With Heart Failure
• Efficacy and Safety of corticoSTEROids Added to Standard Therapy in Patients With Acute Heart Failure (STERO-AHF)
• Acetazolamide Per os for Decompensation of Heart Failure
• The Anti-myocardial Fibrosis Effect of Vericiguat in HFrEF
• Right Ventricular Contractile Reserve in HF
• Administration of the SGLT-2 Inhibitor Dapagliflozin in the Patients With Amyloid Cardiomyopathy
• Effect of Empagliflozin on NT-Pro Brain Natriuretic Peptide in Heart Failure Patients With Reduced Ejection Fraction
• Empagliflozin and Dapagliflozin in Patients Hospitalized for Acute Decompensated Heart Failure
• Mechanisms of Diuretic Resistance in Heart Failure, Aim 2
• Effect of Henagliflozin on Cardiac Function in Type 2 Diabetes Patients With Chronic Heart Failure (HERO-HF)
• The Fontan Dapagliflozin Pilot Study
• A Study of AZD3427 in Participants With Heart Failure and Pulmonary Hypertension Group 2
• SGLT2 Inhibitors and Treatment of Heart Failure in Severe Renal Insufficiency
• COPILOT-HF: Cooperative Program for ImpLementation of Optimal Therapy in Heart Failure
• Effect of Dapagliflozin on Metabolomics and Cardiac Mechanics in Chronic Kidney Disease
• Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
• Impact of Vericiguat on Hemodynamics of Heart Failure
• Beneficial Effects of Vitamin D Combined With Oral Iron Supplementation in Patients With Chronic Heart Failure and Iron Deficiency
• Cardiac Power Output in Cardiogenic Shock Patients
• ORal IrON Supplementation With Ferric Maltol in Treating Iron Deficiency and Anaemia in Patients With Heart Failure (ORION-HF)
• Study of the Safety and Efficacy of Roxadustat in the Treatment of Heart Failure With Chronic Kidney Disease and Anemia
• Empagliflozin in ESKD - A Feasibility Study
• Dapagliflozin, Spironolactone or Both for HFpEF
• Evaluation of GeranylGeranylAcetone in Heart Failure With Preserved Ejection Fraction
• Effect of Short-Term Prednisone Therapy on C-Reactive Protein Change in Emergency Department Patients With Acute Heart Failure and Elevated Inflammatory Markers ( CORTAHF )
• A Study to Evaluate the Safety of mRNA-0184 in Participants With Heart Failure
• A Study to Learn How Well the Drug Vericiguat Works and How Safe it is Under Real World Conditions in Indian Participants After Worsening of a Long-term Heart Condition in Which the Left Side of the Heart Does Not Pump Blood as Well as it Should (Ch
• Prolonged Intravenous Therapy Versus Early Initiation of an Oral Loop Diuretic in Decompensated Heart Failure.
• Phase Ib/IIa Trial With AC01 in Patients With HFrEF
• Colchicine in Patients With Heart Failure and Preserved Left Ventricular Ejection Fraction
• A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and Inflammation
• Metolazone As Early Add On Therapy For Acute Decompensated Heart Failure
• Dapagliflozin Effect on Rheumatic Mitral Stenosis
• A Dose-ranging Trial of OPC-131461 in Cardiac Edema (Congestive Heart Failure [CHF])
• Oxygen Targets in Acute Heart Failure With Pulmonary Congestion
• Losartan in Prevention of Radiation-Induced Heart Failure
• Empagliflozin on the Function of Left Atrium in Heart Failure With Mildly Reduced or Preserved Ejection Fraction
• A Study to Learn How the Study Treatment BAY1753011 Moves Into, Through and Out of the Body, How it Works, How Safe it is, and How it Affects the Body When Given Once as Tablet in Male and Female Participants With Reduced Kidney Function Compared to
• A Phase 2, Adaptive, Double-blinded, Placebo Controlled, Randomized, Multicenter Trial to Evaluate the Efficacy, Safety and Tolerability of Intracoronary Infusion of NAN-101 in Adult Subjects With New York Heart Association (NYHA) Class III Heart Fa
• Ivabradine Effects in Cardiogenic Shock Requiring Inotropic Support
• A Study of LY3540378 in Participants With Worsening Chronic Heart Failure With Preserved Ejection Fraction (HFpEF)
• A Preliminary Study for INFORMED
• Effect of Empagliflozin on Intestinal Microbiota in Patients With Heart Failure (LVEF>40%）
• Shengxian Quyu Decoction in the Treatment of Heart Failure With Reduced Ejection Fraction
• " Evaluation of Safety and Efficacy of Empagliflozin and Sacubitril/Valsartan for CHF With Reduced Ejection Fraction in ACHD "
• LBBP as Initial Therapy in Patients With Non-ischemic Heart Failure and LBBB
• The Inorganic Nitrate and eXercise Performance in Heart Failure (iNIX-HF)
• Sotagliflozin in Heart Failure With Preserved Ejection Fraction (HFpEF) Patients
• Empagliflozin for New On-set Heart Failure Study Regardless of Ejection Fraction
• Empagliflozin in Worsening Heart Failure
• S086 Tablets for Chronic Heart Failure With Reduced Ejection Fraction
• Carvedilol in HF With Reduced Strain and Preserved EF
• Effect of Dapagliflozin on VT in Patients With Heart Failure.
• Precision Treatment With Angiotensin Converting Enzyme Inhibitor
• A Study to Learn How Safe Study Drug BAY2413555 is, How it Affects the Body, and How it Moves Into, Through, and Out of the Body Over 4 Weeks of Use in Participants With Heart Failure and Implanted Cardiac Defibrillator or Cardiac Resynchronization
• Furoscix in Heart Failure Patients With Diuretic Resistance
• The Effect of Sacubitril/Valsartan Versus Ramipril on Left Ventricular Function and Remodeling in Patients With Ischemic Heart Failure With Mid-range Ejection Fraction
• A Study of Ponsegromab in People With Heart Failure
• Pulmonary REsistance Modification Under Treatment With Sacubitril/valsartaN in paTients With Heart Failure With Reduced Ejection Fraction
• Iron Substitution With Ferric Carboxymaltose as Treatment Strategy for Heart Failure Patients With Preserved Ejection Fraction
• Sacubitril/Valsartan in PriMAry preventIoN of the Cardiotoxicity of Systematic breaST canceR trEAtMent (MAINSTREAM)
• Cardiometabolic Effects of Dapagliflozin in Heart Failure With Reduced Ejection Fraction
• The Effect of Vericiguat on Peripheral Vascular Function, Patient Health Status and Inflammation
• Use of a Novel SUBCUTaneous Preparation of Furosemide to Facilitate Early Supported Discharge of Patients With Heart Failure
• Diuretic Treatment in Acute Heart Failure With Volume Overload Guided by Serial Spot Urine Sodium Assessment
• Effectiveness of CRD-740 in Heart Failure
• Effect of Dapagliflozin in Patients With Acute Heart Failure (DAPA-RESPONSE-AHF)
• Early Treatment With a Sodium-glucose Co-transporter 2 Inhibitor in High-risk Patients With Acute Heart Failure
• Safety and Tolerability of Sacubitril/Valsartan in Heart Failure Patient With Reduced Ejection Fraction
• Effects of Triiodothyronine (T3) in Ischemic Heart Failure
• The RENAL LIFECYCLE Trial: A RCT to Assess the Effect of Dapagliflozin on Renal and Cardiovascular Outcomes in Patients With Severe CKD
• Cardiac and Metabolic Effects of Semaglutide in Heart Failure With Preserved Ejection Fraction
• Canagliflozin in Patients With Acute Decompensated Heart Failure
• Corheart 6 Left Ventricular Assist System Prospective, Multicenter, Single-arm Clinical Evaluation Trial
• Safety and Tolerability of Single Ascending Intravenous (IV) Doses of REGN5381 in Adult Heart Failure Patients With Elevated Pulmonary Capillary Wedge Pressure and Reduced Left Ventricular Ejection Fraction
• Study to Assess Efficacy and Safety of CDR132L in Patients With Reduced Left Ventricular Ejection Fraction After Myocardial Infarction
• The Hemodynamic Effects of SGLT2i in Acute Decompensated Heart Failure
• Biomarker Study: Heart Failure Patients at Risk
• Project 2: ACHIEVE- HF
• Pilot Study to Evaluate the Effect of Inflammation in Heart Failure
• Safety and Tolerability Study of XXB750 in Heart Failure Participants With Reduced Ejection Fraction (HFrEF)
• Mechanisms of Diuretic Resistance in Heart Failure
• Single-Ascending Dose Study of JK07 in Subjects With HFpEF
• Ultrafiltration Versus IV Diuretics in Worsening Heart Failure
• Selective PDE9 Inhibition With IMR-687 in Adults With Heart Failure With Preserved Ejection Fraction
• Empagliflozin in Acute Heart Failure
• Impact of Hypertonic Saline Solution on Acute Decompensated Heart Failure
• Screening for Advanced Heart Failure IN Stable outPatientS - The SAINTS Study (SAINTS B)
• Exploratory Ph 2A, Double-Blind, Placebo-Controlled Dose Escalation Study of Safety, Tolerability, PD, & PK of HU6 for Subjects With Obese HFpEF
• HF Patients With LAVDs Being Treated With SGLT2i
• Optimized Treatment of Pulmonary Edema or Congestion
• Sacubitril/Valsartan for CKD5 Stage Dialysis Patients With Heart Failure
• PVP-Guided Decongestive Therapy in HF
• Treating Heart Dysfunction Related to Cancer Therapy With Sacubitril/Valsartan
• Effect of Carvedilol Rapid Up-Titration in Patients With Heart Failure With Reduced Ejection Fraction
• Interleukin-1 Blockade in Acute Myocardial Infarction to Prevent Heart Failure
• Efficacy of Metformin as add-on Therapy in Non-Diabetic Heart Failure Patients
• Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve Decongestion Management System (DMS)
• Program of Angiotensin-Neprilysin Inhibition in Admitted Patients With Worsening Heart Failure (PREMIER)
• ERTU-SODIUM: Study on the Effects of Ertugliflozin on Sodium Storage, Interstitial Volume, and Plasma Volume in HFrEF
• Withdrawal of Pharmacological Treatment in Patients Responding to Cardiac Resynchronization Therapy:
• The Safety of Dapagliflozin in Hemodialysis Patients With Heart Failure
• A Study to Assess the Hemodynamic Effects, Safety, Tolerability, and Pharmacokinetics of Intravenous APD418 in Adult Participants With Heart Failure With Reduced Ejection Fraction
• Impact of Empagliflozin on Functional Capacity in Heart Failure With Preserved Ejection Fraction
• SGLT2i and KNO3 in HFpEF - The SAK HFpEF Trial
• Polydiuretic Therapy for HFpEF, a Randomised Controlled Trial
• Cilostazol for HFpEF
• ARNI Versus plAcebo in Patients With Congenital sYStemic Right Ventricle Heart Failure
• Preliminary Study on the Clinical Effect of Recombinant Human Brain Natriuretic Peptide on Sepsis Complicated With Heart Failure
• A Clinical Trial to Compare the Pharmacokinetics and Safety of "BR1016A" With "BR1016B" in Healthy Volunteers
• A Clinical Trial to Compare the Pharmacokinetics and Safety of "BR1016C" With "BR1016D" in Healthy Volunteers
• Metformin for Older Patients With Heart Failure With Preserved Ejection Fraction Pilot Study
• A Study of Vericiguat (MK-1242) in Participants With Chronic Heart Failure With Reduced Ejection Fraction (HFrEF) (MK-1242-035)
• Torsemide Comparison With Furosemide for Management of Patients With Stable Heart Failure
• The Effect of Angiotensin Receptor-Neprilysin Inhibition on Cardiac Fibrosis in Patients With HFpEF
• Study to Evaluate the Safety and Pharmacokinetics of CKD-349
• A Study in Healthy Adult Male Participants to Learn the Way Vericiguat is Absorbed With and Without Food When Taken as a Single Dose in Liquid Form Suitable for Children Compared to a 10 Milligram (mg) Tablet That Releases the Active Substance Immed
• The Cardiac Effects of Empagliflozin in Patients With High Risk of Heart Failure
• Comparison of Effects of Atorvastatin Versus Rosuvastatin on Cardiac Function in Heart Failure Patients
• Mechanical Left Ventricular Unloading in Acute Decompensated Heart Failure
• Levosimendan in Patients With Impaired Right Ventricular Function Undergoing Cardiac Surgery
• SGLT2 Inhibitors, Ketones, and Cardiovascular Benefit Research Plan
• A First Time in Human (FTIH) Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Repeat Doses of GSK3884464 in Healthy Participants
• The Metabolic Effects of Empagliflozin in Patients With High Risk of Heart Failure
• Thoracentesis to Alleviate Cardiac Pleural Effusion
• The Effects of Neuraminidase Inhibitor Oseltamivir in Patients With Chronic Heart Failure
• Lokelma for RAAS Maximisation in CKD & Heart Failure.
• Effect of Rapamycin to Improve Cardiac Function in Frail Older Adults
• Study to Evaluate the Efficacy and Safety of AZD4831 in Participants With Heart Failure With Left Ventricular Ejection Fraction > 40%
• Efficacy and Safety of Qishenyiqi Dripping Pills for Treating Chronic Heart Failure With Reduced Ejection Fraction (Syndrome of Qi Deficiency and Blood Stasis) Due to Coronary Heart Disease
• Effect of Levosimendan on Left Ventricular Systolic Function and Heart Failure After PCI in Patients With Acute Anterior Myocardial Infarction
• Pivotal Bioequivalence Study to Qualify Manufacturing Site Transfer for Prazosin Hydrochloride Capsules
• Effect of Dapagliflozin on Submaximal Exercise Tolerance in Heart Failure
• Effect of Levosimendan on miRNAs Regulation in the Failing Hearts
• Impact of Intravenous Iron Repletion On Mechanisms of Exercise InTolerance in HFpEF (IRONMET-HFpEF)
• A Study of Sotatercept for the Treatment of Cpc-PH Due to HFpEF
• Efficacy and Safety of Qishenyiqi Dripping Pills for Treating Chronic Heart Failure With Preserved Ejection Fraction
• Research Study to Look at How Well Semaglutide Works in People Living With Heart Failure, Obesity and Type 2 Diabetes
• Matching Perfusion and Metabolic Activity in HFpEF
• Peri-treatment of SGLT-2 Inhibitor on Myocardial Infarct Size and Remodeling Index in Patients With Acute Myocardial Infarction and High Risk of Heart Failure Undergoing Percutaneous Coronary Intervention
• Study to Evaluate the Effects of AZD3427 in Patients With Heart Failure
• Safety & Feasibility of DSR TherApy in Heart FAiluRe pAtients With Persistent Congestion
• Dapagliflozin on Volume Vascular Outcomes.
• Evaluation of the Hemocompatibility of the Direct Oral Anti-Coagulant Apixaban in Left Ventricular Assist Devices
• DAPAgliflozin Versus Thiazide Diuretic in Patients With Heart Failure and Diuretic RESISTance
• Colchicine in HFpEF
• A Study of Tirzepatide (LY3298176) in Participants With Heart Failure With Preserved Ejection Fraction and Obesity (SUMMIT)
• A Study of LY3461767 in Participants With Chronic Heart Failure With Reduced Ejection Fraction
• A Study to Assess the Safety, Tolerability and Efficacy of IONIS-AGT-LRx in Participants With Chronic Heart Failure With Reduced Ejection Fraction
• Study to Assess the Bioavailability of Different Formulations of AZD9977 and Dapagliflozin and Influence of Food in Selected Formulations in Healthy Volunteers
• OPtimizing Aldosterone Receptor Antagonist Therapy by Sodium Zirconium Cyclosilicate in Heart Failure
• Research Study to Investigate How Well Semaglutide Works in People Living With Heart Failure and Obesity
• Acute Reno-Cardiac Action of Dapagliflozin In Advanced Heart Failure Patients on Heart Transplant Waiting List
• Sodium-glucose Cotransporter Type 2 Inhibitors for Acute Cardiorenal Syndrome Prevention
• Impact of Beta-blockers on Physical Function in HFpEF
• A Study of Mavacamten in Participants With HFpEF and Chronic Elevation of cTnI and/or NT-proBNP
• Pilot Deprescribing N-of-1 Trials for Beta-blockers in HFpEF
• Treatment of PH With Angiotensin II Receptor Blocker and Neprilysin Inhibitor in HFpEF Patients With CardioMEMS Device
• Effects of SGLT2 Inhibition on the Mechanisms of Cardiac Damage in the Diabetic Patient With HFpEF
• Telmisartan Versus Enalapril in Heart Failure With Reduced Ejection Fraction Patients With Moderately Impaired Kidney Functions
• Dapagliflozin (DAPA) Effects in HFpEF
• Spironolactone In The Treatment of Heart Failure
• A Trial to Learn How Safe Vericiguat (BAY1021189) is and the Way the Body Absorbs, Distributes and Gets Rid of Vericiguat in Participants With Liver Disease and in Age-, Weight- and Gender-matched Healthy Participants
• A Trial to Learn How Safe Vericiguat (BAY1021189) is and the Way the Body Absorbs, Distributes and Gets Rid of Vericiguat in Participants With Kidney Disease and in Age-, Weight- and Gender-matched Healthy Participants
• Treatment of Pulmonary Hypertension in High-risk Cardiac Surgery Patients Using Inhalational and Intravenous Agents
• Impact on Atrial Remodeling of Dapaglifozin in Patients With Heart Failure .
• Association Between Dapagliflozin-induced Improvement and Anemia in Heart Failure Patients (ADIDAS)
• Randomized Double-blind Trial to Study the Benefit of Colchicine in Patients With Acutely Decompensated Heart Failure
• Levosimendan In Ambulatory Heart Failure Patients
• Calcium Up-Regulation by Percutaneous Administration of Gene Therapy In Cardiac Disease
• Polydiuretic Therapy for Heart Failure With Preserved Ejection Fraction and Diabetes Mellitus
• Effect of Xenon on Brain Injury After Aneurysmal Subarachnoid Hemorrhage
• Effects of APIXaban on BRAIN Protection in Patients With Sinus Rhythm and Heart Failure: APIXBRAIN-HF Trial
• Study on the Clinical and Mechanism of Wenyang Huoxue Decoction in Treating Heart Failure After Myocardial Infarction
• Landiolol for Rate Control in Decompensated Heart Failure Due to Atrial Fibrillation
• GOREISAN for Heart Failure (GOREISAN-HF) Trial
• OUTpatient Intravenous LASix Trial in Reducing Hospitalization for Acute Decompensated Heart Failure
• The Bio-Clinical Effects of the (Sacubitril-Valsartan) Combination on Patients With Chronic Heart Failure
• Study to Assess Efficacy and Safety of SZC for the Management of High Potassium in Patients With Symptomatic HFrEF Receiving Spironolactone
• Clinical and Metabonomics Study on the Treatment of Heart Failure After Myocardial Infarction With Modified Wenxin Decoction
• Mechanisms Underlying Hypotensive Response to ARB/NEP Inhibition - Aim 3
• SGLT2-Inhibitors for Sleep Apnea in Heart Failure
• Polypill Strategy for Heart Failure With Reduced Ejection Fraction
• Assessment of Safety, Tolerability, Immunogenicity, and Pharmacokinetics of AZD3427
• Effects of Furosemide Plus Small HSS in Subjects With Heart Failure With Reduced Ejection Fraction (HFrEF)
• Diuretic and Natriuretic Effect of High-dose Spironolactone in Patients With Acute Heart Failure
• Ertugliflozin to Reduce Arrhythmic Burden in ICD/CRT patientS (ERASe-Trial) - a Phase III Study
• New MRI Methods Applied to Heart Failure With Preserved Ejection Fraction (HFpEF)
• Levosimendan Administration in Pulmonary Hypertension
• Efficacy, Safety and Tolerability of AZD9977 and Dapagliflozin in Participants With Heart Failure and Chronic Kidney Disease
• Clevidipine vs Placebo or Standard of Care for Dyspnea and Blood Pressure Control in AHF
• The DAPA-MEMRI Trial
• Influence of Sacubitril/Valsartan on Autonomic Cardiac Nervous System in Heart Failure Patients: an Exploratory Study
• Empagliflozin and Atrial Fibrillation Treatment
• Dapagliflozin on Hypotensive Heart Failure Patients After Sacubitril/Valsartan Therapy
• Splanchnic Nerve Block for Therapy of Chronic Heart Failure (Splanchnic III)
• The Effectiveness and Safety of Levosimendan in Patients With Severe Aortic Stenosis and Heart Failure Undergoing Transcatheter Aortic Valve Replacement
• Aquapheresis Efficacy in Outpatients With Decompensated Heart Failure
• The Effect of Sacubitril/Valsartan on Cardiovascular Events in Dialysis Patients and Efficacy Prediction of Baseline LVEF Value
• Dapagliflozin And Pulmonary Artery Hemodynamics in Heart Failure With Reduced Ejection Fraction Patients With CardioMEMS®
• Dapagliflozin Effects on Cardiovascular Events in Patients With an Acute Heart Attack
• The Re-Prosper HF Study
• The Influence of Metformin on Chronic Heart Failure Clinical Course in Patients With Prediabetes
• Personalised Risk scOre For Implantation of Defibrillators in Patients With Reduced LVEF≤35% and a Low Risk for Sudden Cardiac Death
• Incretin and Treatment With Inhibition of Sodium-glucose Cotransporter-2 Combination Insights Into Mechanisms Implicated in Congestive Heart Failure: "NATRIURETIC" Trial
• Hypertonic Saline Therapy in Ambulatory Heart Failure Unit.
• Mechanistic Studies of Nicotinamide Riboside in Human Heart Failure
• Effect of Dual Bronchodilation With Umeclidinium/Vilanterol on Patients With COPD, Hyperinflation and Heart Failure
• A Phase IIa Clinical Trial on TSG-01 in the Treatment of Chronic Heart Failure in Patients With Coronary Heart Disease.
• EMPACT-MI: A Study to Test Whether Empagliflozin Can Lower the Risk of Heart Failure and Death in People Who Had a Heart Attack (Myocardial Infarction)
• Efficacy and Safety of TRC041266 in Patients With Heart Failure, LVEF ≥40%, Diastolic Dysfunction and Type 2 Diabetes Mellitus
• Effective Study of ARNI on Ventricular Arrhythmia in HFrEF Patients With ICD or CRT-D
• Validation of ERTugliflozin for Inhibiting Cardiac Fibrosis Using Cardiac MRI and Laboratory Parameters in Korean Heart Failure Patients With Nonischemic Cardiomyopathy(VERTICAL)
• Protocolized Diuretic Therapy Compared to Standard Care in Emergency Department Patients With Acute Heart Failure
• Stratified Treatment to Ameliorate Diastolic Left Ventricular Stiffness in Heart Failure With Preserved Ejection Fraction
• Evaluate the Effect of Injectable Neucardin on the Cardiac Function of Subjects With Chronic Systolic Heart Failure
• Early Sequential Nephron Blockade in Acute Heart Failure Patients: A Randomised, Controlled Study
• Omecamtiv Mecarbil Post-trial Access Study
• Efficacy and Safety of Sacubitril/Valsartan in Maintenance Hemodialysis Patients With Heart Failure
• The Comparison Between Spironolactone and Indapamide Monotherapy or in Combination With Amlodipine to Reduce the Risk of Heart Failure
• Ivabradine in Patients With Congestive Heart Failure
• Ertugliflozin in Acute Heart Failure
• Study to Evaluate the Efficacy (Effect on Disease) and Safety of Finerenone on Morbidity (Events Indicating Disease Worsening) & Mortality (Death Rate) in Participants With Heart Failure and Left Ventricular Ejection Fraction (Proportion of Blood Ex
• BLOCKade of Calcium Channels and Beta Adrenergic Receptors for the Treatment of Hypertension in HFpEF
• Pemziviptadil (PB1046), a Long-acting, Sustained Release Human VIP Analogue, Intended to Provide Clinical Improvement to Hospitalized COVID-19 Patients at High Risk for Rapid Clinical Deterioration and Acute Respiratory Distress Syndrome (ARDS).
• Growth Hormone in Ischemic Heart Failure
• Early Administration of Ivabradine in Children With Heart Failure
• Dapagliflozin in Diabetic Patients (Type 2) With Decompensated Heart Failure
• Crossover Study to Compare the Pharmacokinetics and Bioavailability of a Novel Furosemide Regimen Administered Subcutaneously vs. the Same Dose Administered Intravenously in Subjects With Chronic Heart Failure
• Nutritional Ketosis in Heart Failure
• Pilot Study on Withdrawal of Spironolactone Among Heart Failure With Improved Ejection Fraction
• Phase I, First-In-Human Study of TT-00920 in Healthy Subjects
• Dapagliflozin and Effect on Cardiovascular Events in Acute Heart Failure -Thrombolysis in Myocardial Infarction 68 (DAPA ACT HF-TIMI 68)
• Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present With Symptomatic Heart Failure With Reduced Ejection Fraction (HFrEF): The CORCINCH-HF Study
• Tolvaptan add-on Therapy to Overcome Loop Diuretic Resistance in Acute Heart Failure With Renal Dysfunction
• Study of Verinurad in Heart Failure With Preserved Ejection Fraction
• Effects of Sitagliptin in Individuals With Genetically Decreased DPP4
• Study to Evaluate Sex Differences in the Acute Effects of PL-3994 in Heart Failure Subjects
• Study of the Safety of BMS-986259 in Participants With Post-Acute Decompensated Heart Failure
• The Efficacy and Safety of Zhigancao Tang Granule for HFpEF of Qi-Yin Dificiency
• Efficacy of Ivabradine in Patient With Both Persistent Atrial Fibrillation and Heart Failure With Reduce Ejection Fraction
• Value of SGLT2 Inhibitor (Dapagliflozin) as an Added Therapy in Diabetic Patients With Heart Failure With Reduced Ejection Fraction; Randomized Controlled Clinical Trial
• Efficacy and Safety of Dapagliflozin in Acute Heart Failure
• Adrecizumab Dose Escalation Safety and Tolerability Evaluation (ADESTE)
• A Study on Impact of Canagliflozin on Health Status, Quality of Life, and Functional Status in Heart Failure
• Dapagliflozin Heart Failure Readmission
• NATriuretic Response to Expansion and dIUretics in huMans With Heart Failure
• A Study to Assess the Effect AZD4831 in Japanese and Chinese Healthy Volunteers
• Evaluation on Performance and Oxydative Stress in Patient With Iron deficIency and Stable Heart Failure Study
• The Prognostic Impact of Using High-dose Hydralazine in Severe Systolic Heart Failure With Hemodynamically Significant Mitral Regurgitation
• Study of JK07 in Subjects With Heart Failure With Reduced Ejection Fraction (HFrEF)
• The Persistence of Autoantibody Neutralisation by BC 007 in Patients With Chronic HFrEF and Autoantibodies Against the Beta1-Adrenergic Receptor
• Safety and Efficacy of ARNI After LVAD ImplanT (SEAL-IT) Study
• Sequential Nephron Blockade in Acute Heart Failure
• Treatment Of Atrial Fibrillation In Preserved Cardiac Function Heart Failure
• Interest of Levosimendan in Reducing Weaning Failures of ExtraCorporeal Life Support - ECLS
• A Study to Test the Effect of Empagliflozin in Patients Who Are in Hospital for Acute Heart Failure
• Effects of Sacubitril/Valsartan on Subclinical Heart Failure in HIV (The ENCHANTMENT HIV Study)
• RELieving Increasing oEdema Due to Heart Failure
• Study of Sacubitril/ValsarTan on MyocardIal OxygenatioN and Fibrosis in Heart Failure With Preserved Ejection Fraction
• Mechanisms Underlying Hypotensive Response to ARB/NEP Inhibition - Aim 2
• Developing Oral LT3 Therapy for Heart Failure - HFrEF
• Developing Oral LT3 Therapy for Heart Failure - HFpEF
• Comparison of BNP and NT-proBNP in the Management of Patients With Chronic and Acute Heart Failure
• Sacubitril/Valsartan in Left Ventricular Assist Device Recipients
• Hepato-renal Regulation of Water Conservation in Heart Failure Patients With SGLT-2 Inhibitor Treatment
• How to Prevent Heart Failure Readmission by Using Lung Impedance Device (HOPE-HF Study)
• Non Invasive Assessment of Heart Failure
• Evaluating Metabolic Mechanisms of Ertugliflozin in Diabetes & Heart Failure
• The ARIES HeartMate 3 Pump IDE Study
• IV Iron in Acute Decompensated Heart Failure
• Safety and Efficacy of Early, seQUential Oral dIuretic Nephron blockAde In Acute Heart Failure
• Effects of Empagliflozin on Diuresis and Renal Function in Patients With Acute Decompensated Heart Failure
• Clinical Study to Assess Safety, PK and PD Parameters of CDR132L
• The Study of Qishenyiqi Drop Pills in Improving the Prognosis of Heart Failure Patients
• Efficacy and Safety of Sacubitril/Valsartan Compared With Enalapril on Morbidity, Mortality, and NT-proBNP Change in Patients With CCC
• Risk-Guided Cardioprotection With Carvedilol in Breast Cancer Patients Treated With Doxorubicin and/or Trastuzumab
• Comparing Diuretic Strategies in Hospitalized Heart Failure
• Peritoneal Ultrafiltration in Cardio Renal Syndrome.
• Iron in Patients With Cardiovascular Disease
• Standard-dose Apixaban AFtEr Very Low-dose ThromboLYSis for Acute Intermediate-high Risk Acute Pulmonary Embolism
• Changes in NT-proBNP and Outcomes, Safety, and Tolerability in HFpEF Patients With Acute Decompensated Heart Failure (ADHF) Who Have Been Stabilized During Hospitalization and Initiated In-hospital or Within 30 Days Post-discharge (PARAGLIDE-HF)
• A Registry-based Cluster Randomized Trial to Compare the Effect of Spironolactone vs. Eplerenone on Clinical Outcomes in Patients With Symptomatic Systolic Heart Failure
• Sodium-glucose Co-transporter 2 Inhibitors Effects in Failing Heart Patients
• Safety Trial of OPC-61815 Injection in Patients With Congestive Heart Failure Who Have Difficulty With or Are Incapable of Oral Intake
• Effect of Doxycycline on Cardiac Remodelling in STEMI Patients
• Carvedilol SR Study for Biomarkers From Blood and Urine and Safety of in Patients With Heart Failure With Preserved Ejection Fraction
• Prevention of Heart Failure Induced by Doxorubicin With Early Administration of Dexrazoxane
• LCZ696 in Advanced LV Hypertrophy and HFpEF
• Beta 3 Agonist Treatment in Heart Failure-2
• Cardiac Perfusion and Metabolism With [11C] Acetate PET/CT is Associated With Hematopoietic System Activation in Acute Decompensated Heart Failure: An Imaging Sub-study
• COmparing arNi and Ace For Improving Erectile Dysfunction in mEN With reduCed Ejection Fraction Heart Failure
• An Open-label Extension Study Evaluating Safety and Tolerability of LCZ696 in Subjects Who Completed PARAGON-HF in Japan.
• A Trial to Study BAY1753011 in Patients With Congestive Heart Failure
• Effect of Melatonin on Cardiovascular and Muscle Mass and Function in Patients With Heart Failure
• Protocol of Diuretics Use in Congestive Therapy in Heart Failure
• Transcatheter Mitral Valve Repair for the Treatment of Mitral Valve Regurgitation In Heart Failure (The EVOLVE-MR Trial)
• A Pharmacokinetics, Safety and Tolerability Study of Multiple Formulations of BMS-986231 in Healthy Participants
• Patiromer for the Management of Hyperkalemia in Subjects Receiving RAASi Medications for the Treatment of Heart Failure (DIAMOND)
• Metoprolol XR in Heart Failure With Normal Ejection Fraction
• DETERMINE-reduced - Dapagliflozin Effect on Exercise Capacity Using a 6-minute Walk Test in Patients With Heart Failure With Reduced Ejection Fraction
• DETERMINE-preserved - Dapagliflozin Effect on Exercise Capacity Using a 6-minute Walk Test in Patients With Heart Failure With Preserved Ejection Fraction
• Study to Evaluate Effects of INL1 in Patients With Heart Failure and Reduced Ejection Fraction
• β-blockers Withdrawal in Patients With HFpEF and Chronotropic Incompetence: Effect on Functional Capacity (Preserve-HR)
• Ferric Carboximaltose on Intra-myocardial Iron Load in Patients With Heart Failure
• Randomized Evaluation and Verification of Ventricular Enhancement
• A Phase 1 Study to Assess the Pharmacokinetics of AZD9977 Administered Alone and in Combination With Itraconazole in Healthy Volunteers
• Blend to Limit Oxygen in ECMO: A Randomised Controlled Registry Trial
• The Impact of Magnesium on Exercise Tolerance, Quality of Life and Clinical Outcomes in Chronic Heart Failure Patients
• Evaluation of Renal Sodium Excretion After Salt Loading in Heart Failure With Preserved Ejection Fraction
• Effects of Iron Therapy in Heart Failure With Preserved Ejection Fraction and Iron Deficiency (PREFER-HF)
• Efficacy and Safety of Ivabradine to Reduce Heart Rate Prior to Coronary CT-angiography in Advanced Heart Failure: Comparison With β-Blocker
• Effect of Angiotensin-Neprilysin Inhibition (ARNI) on Prognosis of Chronic Heart Failure
• A Study to Assess the Reaction of Body for Four Different Formulations of AZD9977 (Part A) and Influence of Food and Lower Dose of a Selected Formulation (Part B) in Healthy Male Subjects
• Effects of Iron Therapy and Exercise Training in Patients With Heart Failure and Iron Deficiency
• A Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD9977 in Japanese Healthy Participants With Single and Multiple Ascending Dose Administration
• Zero Sodium Peritoneal Dialysate Protocol Pilot Study
• Interleukin-1 Blockade In Recently Decompensated Heart Failure - 2
• EVOlocumab in Stable Heart Failure With Reduced Ejection Fraction of Ischemic Etiology: EVO-HF Pilot
• Chlorhexidine Mouthwash and Oral Nitrate in Adults With Pulmonary Hypertension
• CLCZ696B2319E1 OL Extension Study to Evaluate Long-term Safety of Sacubitril/Valsartan in Pediatric Patients With HF
• Efficacy of Omega-3 Fatty Acid Therapy in Preventing Gastrointestinal Bleeding in Patients With CF-LVAD
• Digoxin Evaluation in Chronic Heart Failure: Investigational Study In Outpatients in the Netherlands
• Anti-thrombotic Monotherapy in HeartMate 3 Left Ventricular Assist System (LVAS)
• Treatment of GHD Associated With CHF
• ORal IrON Supplementation With Ferric Maltol in Patients With Heart Failure Carrying Left Ventricular Assist Devices
• Efficacy and Safety Trial of OPC-61815 Injection Compared With Tolvaptan 15-mg Tablet in Patients With Congestive Heart Failure
• Observation on the Effect of Sacubitril/Valsartan in Advanced Chronic Kidney Disease（CKD）Patients With Heart Failure
• Effectiveness of a Repetitive Use of 24-hour Levosimendan Infusions in Patients With Severe Systolic Heart Failure in Order to Prevent Rehospitalizations
• Prevention of Cardiac Dysfunction During Breast Cancer Therapy
• Study to Assess the Effect of Omecamtiv Mecarbil on Exercise Capacity in Subjects With Heart Failure
• Safety and Tolerability Study of AZD4831 in Patients With Heart Failure.
• Effects of Empagliflozin on Exercise Capacity and Left Ventricular Diastolic Function in Patients With Heart Failure With Preserved Ejection Fraction and Type-2 Diabetes Mellitus
• Diuretic Effect of Metolazone Pre-dosing Versus Concurrent Dosing
• The Impact of Low Flow Nocturnal Oxygen Therapy on Hospital Admissions and Mortality in Patients With Heart Failure and Central Sleep Apnea
• An Investigational Study of Continuous 8-Hour Intravenous Administrations of BMS-986231 in Participants With Heart Failure and Reduced Heart Function Given a Standard Dose of Loop Diuretic
• Acetazolamide in Patients With Acute Heart Failure
• The Effects of Neprilysin on Glucagon-like Peptide-1
• Effect of Ertugliflozin on Cardiac Function in Diabetes
• A Long Term Study to Find Out if Macitentan is an Effective and Safe Treatment for Patients With Heart Failure With Preserved Ejection Fraction and Pulmonary Vascular Disease
• Oral dIuretics in Very Intensive Treatment, an Early Intervention in Outpatients With Heart Failure
• Anti-thrombotic Monotherapy With the HeartMate 3 LVAS
• Early Use of Ivabradine in Heart Failure
• Personalized Treatments for Depressive Symptoms in Patients With Advanced Heart Failure
• Study in HFpEF Patients to Compare the Effect of AZD9977 and Spironolactone on Serum Potassium
• Insulin Treatment in Diabetic Older People With Heart Failure.
• Ivabradine to Prevent Anthracycline-induced Cardiotoxicity
• An Investigational Study to Evaluate Experimental Medication BMS-986224 in Renally Impaired Participants
• Cannabidiol in Patients With Heart Failure Failure in AHA/ACC Stages A-C
• Ivabradine in Stage D Heart Failure Patients on Chronic Inotropes
• Metformin for Pulmonary Hypertension HFpEF
• Open-Label Rollover Study of Levosimendan in PH-HFpEF Patients
• Inhaled Iloprost and Exercise Hemodynamics and Ventricular Performance in Heart Failure With Preserved Ejection Fraction
• Dapagliflozin Evaluation to Improve the LIVEs of Patients With PReserved Ejection Fraction Heart Failure.
• MPO Inhibitor A_Zeneca for HFpEF
• Diuretic Response in Advanced Heart Failure: Bolus Intermittent vs Continuous INfusion
• Effect of Intravenous Metoprolol Combining RIC on Myocardial Protection in STEMI Patients
• Effect of Levosimendan or Placebo on Exercise in Advanced Chronic Heart Failure
• Prospective Comparison of Metolazone Versus Chlorothiazide for Acute Decompensated Heart Failure With Diuretic Resistance
• Understanding the Cardiovascular Benefits of the Anti-Diabetes Medication SGLT2 Inhibitors
• Levosimendan for Cardiac Patients Undergoing Major Abdominal Cancer Surgeries
• Evaluate the Efficacy and Safety of Short-term Administration of SIMDAX
• Repurposing a Histamine Antagonist to Benefit Patients With Pulmonary Hypertension
• EMPA Acute Heart Failure
• Pharmacodynamic Effects of Sacubitril/Valsartan on Natriuretic Peptides, Angiotensin and Neprilysin
• The Effects of Sacubitril/Valsartan Compared to Valsartan on LV Remodelling in Asymptomatic LV Systolic Dysfunction After MI
• Imaging Histone Deacetylase in the Heart
• Patient-reported Outcomes in Vericiguat-treated Patients With HFpEF
• Hemodynamic Evaluation of Levosimendan in Patients With PH-HFpEF
• Study of Dapansutrile Capsules in Heart Failure
• Potassium Reduction Initiative to Optimize RAAS Inhibition Therapy With Sodium Zirconium Cyclosilicate in Heart Failure
• Evaluating the Clinical Efficacy of Resveratrol in Improving Metabolic and Skeletal Muscle Function in Patients With Heart Failure
• Effect of Sotagliflozin on Cardiovascular Events in Patients With Type 2 Diabetes Post Worsening Heart Failure (SOLOIST-WHF Trial)
• An Investigational Study of Experimental Medication BMS-986231 Given in Participants With Different Levels of Liver Function
• DANHEART (H-HeFT and Met-HeFT)
• Phase I Study of OPC-61815
• Doxycycline to Protect Heart Muscle After Heart Attacks
• Circulating NEP and NEP Inhibition Study in Heart Failure With Preserved Ejection Fraction
• Acetazolamide in Decompensated Heart Failure With Volume OveRload (ADVOR)
• Clinical Study of Lipoic Acid on Ischemic Heart Failure
• Rivaroxaban Once Daily Versus Dose-adjusted Vitamin K Antagonist on the Biomarkers in Acute Decompensated Heart Failure and Atrial Fibrillation (ROAD HF-AF)
• Effect of BIA 5 1058 on Cardiac Repolarization
• Studies of Empagliflozin and Its Cardiovascular, Renal and Metabolic Effects
• Sodium Chloride and Contrast Nephropathy
• Sildenafil in US Heart Failure Patients (SilHF-US)
• A Study of Ivabradine in African-American/ Black Subjects With Heart Failure and Left Ventricular Systolic Dysfunction.
• Abdominal Nerve Blockade in Chronic Heart Failure.
• This Study Tests Empagliflozin in Patients With Chronic Heart Failure With Reduced Ejection Fraction (HFrEF). The Study Looks at How Far Patients Can Walk in 6 Minutes and at Their Heart Failure Symptoms
• This Study Tests Empagliflozin in Patients With Chronic Heart Failure With Preserved Ejection Fraction (HFpEF). The Study Looks at How Far Patients Can Walk in 6 Minutes and at Their Heart Failure Symptoms.
• Study Evaluating the Safety, Tolerability and Preliminary Pharmacokinetics and Pharmacodynamics of MYK-491
• Mechanism and Effects of Manipulating Chloride Homeostasis in Acute Heart Failure
• Mechanism and Effects of Manipulating Chloride Homeostasis in Stable Heart Failure
• Repetitive Levosimendan Infusion for Patients With Advanced Chronic Heart Failure
• Nicotinamide Riboside in Systolic Heart Failure
• A Pilot Study: Preventing Adverse Remodelling Following Pacemaker Implantation
• Randomized Clinical Trial to Evaluate the Regenerative Capacity of CardioCell in Patients With Chronic Ischaemic Heart Failure (CIHF)
• ERtugliflozin triAl in DIabetes With Preserved or Reduced ejeCtion FrAcTion mEchanistic Evaluation in Heart Failure
• Influences of Angiotensin-neprilysin Inhibition on Sympathetic Activity in Heart Failure
• Transthyretin Cardiac Amyloidosis in HFpEF
• Changes in Myocardial Iron After Iron Administration
• Prophylactic Lisinopril to Prevent Anthracycline Cardiomyopathy.
• Survival Study of the Recombinant Human Neuregulin-1β in Subjects With Chronic Heart Failure.
• Effect of Ivabradine in Stage D HF/Cardiogenic Shock Patients on Dobutamine
• Randomized, Double-Blind, Placebo-Controlled, Safety and Tolerability Study of ITI-214 in Patients With Heart Failure
• Transplant of Redeemed Organs by Judicious Administration of New Direct-Acting Antivirals for Hepatitis-C Heart Recipients
• Effect of Intravenous FerRic carbOxymaltose oN Reverse Remodeling Following Cardiac Resynchronization Therapy
• Retrograde Application of Bone Marrow Aspirate Concentrate
• AZD8601 Study in CABG Patients
• AC6 Gene Transfer in Patients With Reduced Left Ventricular Ejection Fraction Heart Failure
• A Study of Continuous Infusions of HNO (Nitroxyl) Donor in Patients With Heart Failure and Impaired Systolic Function
• Sildenafil for the Prevention of Right Heart Failure Following LVAD Implantation
• Evaluating Iron Protein Succinylate Oral Solution in Treating Chronic Heart Failure and Iron Deficiency
• Spironolactone Therapy in Chronic Stable Right HF Trial
• Administration of Prothrombin Complex Concentrate vs. Standard Transfusion During/After Heart Transplantation
• the Effects of YangXinShi (YXS) on the Quality of Life and Exercise Tolerance in Patients With Chronic Heart Failure
• Safety of HMA-CD20 in Patients With HFrEF
• A Study That Looks at the Function of the Heart in Patients With Heart Failure Who Take Empagliflozin
• A Study of Experimental Medication BMS-986231 in Patients With Different Levels of Kidney Function
• Metformin in Heart Failure Without Diabetes
• Study to Evaluate the Safety, Tolerability and Pharmacokinetics of AMG 986 Administered Orally to Healthy Volunteers and Participants With Severely Impaired Renal Function
• Improving Sleep Quality in Heart Failure
• Short Stay Unit vs Hospitalization in Acute Heart Failure
• The Effects of Sacubitril/Valsartan on Cardiac Oxygen Consumption and Efficiency of Cardiac Work in Heart Failure Patients
• Impact of a Short-term Treatment With Canagliflozin (Canacardia-HF)
• TRANSFORM-HF: ToRsemide compArisoN With furoSemide FORManagement of Heart Failure
• Safety, Tolerability and Pharmacodynamic Activity of Sotagliflozin in Hemodynamically Stable Participants With Worsening Heart Failure
• Treatment of HFpEF With Nitrate Supplement
• Incretin and CRTd.
• A Study of BMS-986224 in Healthy Subjects and Heart Failure Patients With Reduced Ejection Fraction
• Sacubitril-valsartan Versus Usual Anti-hypertensives in LVAD
• Study to Evaluate the Safety and Tolerability of AMG 986 in Healthy Subjects and Heart Failure Patients
• Empagliflozin Versus Placebo on the Rate of Arrhythmic Events in Heart Failure Patients
• Nitroglycerin vs. Furosemide Using Lung Ultrasound Pilot Trial
• Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics Study of Tolvaptan in Pediatric Congestive Heart Failure (CHF) Patients With Volume Overload
• A Study of the Effect of IW-1973 on the Exercise Capacity of Patients With Heart Failure With Preserved Ejection Fraction (HFpEF)
• Clinical Pharmacology Trial to Investigate the Dose of OPC-61815 Injection Equivalent to Tolvaptan 15-mg Tablet in Patients With Congestive Heart Failure
• LINQ for impEdance meAsuremeNt While Off From HF Medication Study
• Noninvasive Real-time Intracardiac Pressure Measurements Using Subharmonic Ultrasound
• Noninvasive, Subharmonic Intra-Cardiac Pressure Measurement
• SGLT2 Inhibition in Combination With Diuretics in Heart Failure
• Ferric Carboxymaltose to Improve Skeletal Muscle Metabolism in Heart Failure Patients With Functional Iron Deficiency
• CRD-102 for Right Heart Failure in Patients With Left Ventricular Assist Devices
• Within Subject Variability Study of ER Torsemide 20 mg Tablet in Healthy Subjects
• Pharmacokinetics and Metabolism of [14C] BMS-986231 in Healthy Male Participants
• Immediate Release Versus Slow Release Carvedilol in Heart Failure
• Effects of Empagliflozin on Clinical Outcomes in Patients With Acute Decompensated Heart Failure
• The Effect of Neprilysin (LCZ696) on Exercise Tolerance in Patients With Heart Failure
• Early Management Strategies of Acute Heart Failure for Patients With NSTEMI
• Weight-Based Torsemide Dosing in Subjects With Heart Failure
• Statins for the Primary Prevention of Heart Failure in Patients Receiving Anthracycline Pilot Study
• The Study of Heart Failure With Human Umbilical Cord Mesenchymal Stem Cells (hUC-MSC)
• Baduanjin-eight-silken-movement With Self-efficacy Building for Patients With Chronic Heart Failure (BESMILE-HF Study)
• Differential Vascular and Endocrine Effects of Valsartan/Sacubitril in Heart Failure With Reduced Ejection Fraction
• Trial Assessing the Effectiveness of Ivabradine Started at Discharge From the Observation Unit
• Angiotensin (1-7) Treatment to Improve Cognitive Functioning in Heart Failure Patients
• A Study to Evaluate Whether Macitentan is an Effective and Safe Treatment for Patients With Heart Failure With Preserved Ejection Fraction and Pulmonary Vascular Disease
• A Dose Finding Study to Assess the Effect of LIK066 Compared to Placebo or Empagliflozin in Patients With Type 2 Diabetes Mellitus and Heart Failure
• Zepatier For Treatment Of Hepatitis C-Negative Patients Who Receive Heart Transplants From Hepatitis C-Positive Donors (HCV)
• B-lines Lung Ultrasound Guided ED Management of Acute Heart Failure Pilot Trial
• CoQ10 and D-ribose in Patients With Diastolic Heart Failure
• Analysing the Effect of Empagliflozin on Reduction of Tissue Sodium Content in Patients With Chronic Heart Failure
• Comparing ARNI With ACE Inhibitor on Endothelial Function
• A Trial to Study Neladenoson Bialanate Over 20 Weeks in Patients With Chronic Heart Failure With Preserved Ejection Fraction
• Thyroid Hormone Replacement for Subclinical Hypothyroidism and Chronic Heart Failure (ThyroHeart-CHF)
• Subcu Administration of CD-NP in Heart Failure Patients With Left Ventricular Assist Device Support
• Impact of EMpagliflozin on Cardiac Function and Biomarkers of Heart Failure in Patients With Acute MYocardial Infarction
• Inhaled Selective Pulmonary Vasodilators for Advanced Heart Failure Therapies and Lung Transplantation Outcomes
• Intravenous Iron in paTients With Heart failURe and Reduced Ejection fracTion (HFREF) pLus Iron dEficiency
• MAGENTUM 1 HeartMate 3 LVAS: A Single Center Prospective Controlled Study (MAGENTUM 1)
• Effect of IV Iron in Patients With Heart Failure With Preserved Ejection Fraction
• Pericardial Resection to Treat Heart Failure
• A Randomized, Double-blind Controlled Study Comparing LCZ696 to Medical Therapy for Comorbidities in HFpEF Patients
• Interleukin-1 Blockade for the Treatment of Heart Failure in Patients With Advanced Chronic Kidney Disease
• EMPagliflozin outcomE tRial in Patients With chrOnic heaRt Failure With Reduced Ejection Fraction (EMPEROR-Reduced)
• EMPagliflozin outcomE tRial in Patients With chrOnic heaRt Failure With Preserved Ejection Fraction (EMPEROR-Preserved)
• Open-label Extension of Oral Treprostinil in Subjects With PH Associated With HFpEF
• Effective Management of Emotional Response to Generate Well-Being Post-HF Exacerbation
• Treatment With IV Iron in Hospitalized Patients With Severe Heart Failure But Without Iron Deficiency
• Randomized Placebo-controlled Trial of FCM as Treatment for Heart Failure With Iron Deficiency
• Oral Treprostinil in Subjects With Pulmonary Hypertension Associated With Heart Failure With Preserved Ejection Fraction
• Intravenous Iron in Patients With Systolic Heart Failure and Iron Deficiency to Improve Morbidity & Mortality
• Study to Evaluate the Effect of Dapagliflozin on the Incidence of Worsening Heart Failure or Cardiovascular Death in Patients With Chronic Heart Failure
• Dapagliflozin in PRESERVED Ejection Fraction Heart Failure
• Empagliflozin Impact on Hemodynamics in Patients With Heart Failure
• Empagliflozin in Heart Failure: Diuretic and Cardio-Renal Effects
• Evaluating the Safety and Efficacy of Qishen Granules Among Patients With Chronic Heart Failure
• Efficacy of Oral Bisoprolol on Heart Rate Reduction in Chinese Chronic Heart Failure Participants
• Safety and Efficacy of ANX-042 in Human Cardiorenal Syndrome
• Evaluate the Safety and Efficacy of 48-Hour Infusions of HNO (Nitroxyl) Donor in Hospitalized Patients With Heart Failure
• Oral Nitrite in Patients With Pulmonary Hypertension and Heart Failure With Preserved Ejection Fraction
• Mechanism(s) Underlying Cardiovascular Effects of ARB/NEP Inhibition - Aim 2
• Short Term Oral Iron Supplementation in Systolic Heart Failure Patients Suffering From Iron Deficiency Anemia
• A Trial to Study Neladenoson Bialanate Over 20 Weeks in Patients With Chronic Heart Failure With Reduced Ejection Fraction
• Evaluation of Outcomes of CRT and MitraClip for Treatment of Low Ejection Fraction and Functional Mitral Regurgitation in HF
• A Study of Oral Nitrate in Adults With Pulmonary Hypertension With Heart Failure and Preserved Ejection Fraction
• Betadine Pleurodesis Via Tunneled Pleural Catheters
• Diffusion MRI in Heart Failure
• Levosimendan Compassionate Use in Pediatric Patients With Advanced Decompensated Heart Failure
• Pulse Reduction On Beta-blocker and Ivabradine Therapy
• Study on the Effects of Sacubitril/Valsartan on Physical Activity and Sleep in Heart Failure With Reduced Ejection Fraction Patients.
• Donor Bone Marrow Derived Mesenchymal Stem Cells in Controlling Heart Failure in Patients With Cardiomyopathy Caused by Anthracyclines
• Tolvaptan for Advanced or Refractory Heart Failure
• PAtient RegisTry Assessing Effectiveness and Safety of HEart Failure treatmeNt With LCZ696 acrOss CaNada
• Use of Oxygen in Heart Failure With Preserved Ejection Fraction
• STOP-CA (Statins TO Prevent the Cardiotoxicity From Anthracyclines)
• Risk Stratification of Heart Failure in Cardiomyopathies.
• Diltiazem vs. Metoprolol in the Acute Management of AF in Patients With HFrEF
• Study to Compare Ferric Carboxymaltose With Placebo in Patients With Acute Heart Failure and Iron Deficiency
• Study With Healthy Japanese and Non-Asian Participants With BMS-986231
• The Efficacy and Safety of Pirfenidone in Patients With Heart Failure and Preserved Left Ventricular Ejection Fraction
• Registrational Study With Omecamtiv Mecarbil (AMG 423) to Treat Chronic Heart Failure With Reduced Ejection Fraction
• A Phase I Study to Assess the Pharmacokinetics of GSK2798745 Tablets
• Treatment of Diabetes in Patients With Systolic Heart Failure
• Oral Nitrite for Older Heart Failure With Preserved Ejection Fraction
• Mechanistic Evaluation of Glucose-lowering Strategies in Patients With Heart Failure
• Sacubitril-valsartan and Heart Failure Patients : the ENTRESTO-SAS Study
• A Phase 2 Study to Evaluate the Cardiac and Renal Effects of Short Term Treatment With Elamipretide in Patients Hospitalized With Congestion Due to Heart Failure
• Safety of Continuing CHemotherapy in Overt Left Ventricular Dysfunction Using Antibodies to HER-2
• Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure With Preserved Ejection Fraction
• randOmized stUdy Using acceleromeTry to Compare Sacubitril/valsarTan and Enalapril in Patients With Heart Failure
• Sodium Thiosulfate to Preserve Cardiac Function in STEMI
• Haemodynamic Effects of Dobutamine and Nitrite in LV Dysfunction
• Effects of Sacubitril/Valsartan Therapy on Biomarkers, Myocardial Remodeling and Outcomes.
• Inhaled Beta-adrenergic Agonists to Treat Pulmonary Vascular Disease in Heart Failure With Preserved EF (BEAT HFpEF): A Randomized Controlled Trial
• Efficacy and Safety of LCZ696 Compared to Valsartan on Cognitive Function in Patients With Chronic Heart Failure and Preserved Ejection Fraction
• Subcutaneous Furosemide in Acute Decompensated Heart Failure Pilot
• A Clinical Research of Qi Deficiency and Blood Stasis Syndrome (Different Disease With Syndrome)
• Study of Effects of Sacubitril/Valsartan vs. Enalapril on Aortic Stiffness in Patients With Mild to Moderate HF With Reduced Ejection Fraction
• Stem Cells Therapy in Advanced Heart Failure
• Study of Organ Perfusion With Custodiol-N Solution Compared With Custodiol Solution in Heart Transplantation
• Open-Label Study of Perhexiline in Patients With Hypertrophic Cardiomyopathy and Moderate to Severe Heart Failure
• A Study of Vericiguat in Participants With Heart Failure With Reduced Ejection Fraction (HFrEF) (MK-1242-001)
• A Pilot Feasibility Study in Recovered Heart Failure
• Hepatitis C Virus(HCV) Heart and Lung Study
• Cardiac Contractility Modulation (CCM) Therapy in Subjects With Medically Refractory Heart Failure
• Tolerability, Pharmacokinetics and Dopamine ß-hydroxylase (DßH) Inhibition Profile of BIA 5-453
• Effect of KNO3 Compared to KCl on Oxygen UpTake in Heart Failure With Preserved Ejection Fraction (KNO3CK OUT HFPEF)
• Tolerability, Pharmacokinetics and Pharmacodynamics of Six Multiple Rising Dose Regimens of BIA 5-453
• Prevention of Non-Surgical Bleeding by Management of HeartMate II Patients Without Antiplatelet Therapy
• The TRUST Trial - CardioVascular Imaging ECHO
• The TRUST Study - CardioVascular Imaging IMT
• Predischarge Initiation of Ivabradine in the Management of Heart Failure (PRIME-HF)
• High-dose Aldosterone Antagonist for Acute Decompensated Heart Failure
• A First-in-Human Study of the Safety of Single Continuous Intravenous (IV) Infusions of CXL-1427 for up to 48 Hours in Healthy Volunteers
• EntrestoTM (LCZ696) In Advanced Heart Failure (LIFE Study)
• A Study to Evaluate the Effects of 4 Weeks Treatment With Subcutaneous Elamipretide on Left Ventricular Function in Subjects With Stable Heart Failure With Preserved Ejection Fraction
• Cardiac Effects of Fixed-dose Dual Bronchodilator in Patients With Heart Insufficiency and COPD
• Effects of Metformin Treatment on Myocardial Efficiency in Patients With Heart Failure
• Perioperative Antibiotic Therapy to Prevent Cardiac Implantable Electronic Device Infections.
• Study to Assess the Safety, Tolerability and PK Response and Explore the PD Response Following 4 Weekly SC Injections of PB1046 in Subjects With Stable Heart Failure With Reduced Ejection Fraction (HFrEF)
• Product Design Clinical Performance Study of sc2Wear Furosemide Combination Product
• Pilot Study for First Clinical Use of sc2Wear Furosemide Combination Product
• Metformin Pharmacokinetics in Patients With Chronic and Acute Heart Failure
• Inorganic NItrate and EXercise Performance in Heart Failure (iNIX-HF): Dose Response
• Intensive Versus Conventional Digoxin Use in Patients With Heart Failure
• Effect of Elamipretide on Left Ventricular Function in Subjects With Stable Heart Failure With Reduced Ejection Fraction
• Pulmonary Artery Pressure Reduction With ENTresto (Sacubitril/Valsartan)
• Evaluation of the Entresto Effect on Sympathic Nervous System in Patient With Heart Failure
• QUantum Genomics Incremental Dosing in Heart Failure - QUID-HF
• Ubiquinol Treatment in Patients With Heart Failure and Preserved Ejection Fraction
• Beta3 Agonist Treatment in Chronic Pulmonary Hypertension Secondary to Heart Failure
• Hemodynamic Response to Exercise in HFpEF Patients After Upregulation of SERCA2a
• Ruboxistaurin in New York Heart Failure Classification III-IV Patients
• Exercise Capacity Study of LCZ696 vs. Enalapril in Patients With Chronic Heart Failure and Reduced Ejection Fraction.
• Intravenous Vasodilator vs. Inotropic Therapy in Patients With Heart Failure
• Influenza Vaccine To Prevent Adverse Vascular Events (RCT-IVVE)
• Demonstration of Reverse Remodeling Effects of Entresto. Using Echocardiography Endocardial Surface Analysis
• Pharmacodynamic Effects of Riociguat in Pulmonary Hypertension and Heart Failure With Preserved Ejection Fraction
• Inorganic Nitrite Delivery to Improve Exercise Capacity in HFpEF
• Iron Stores and Skeletal Muscle Metabolism in Chronic Heart Failure
• A Study to Investigate the Safety and Efficacy of a Novel Furosemide Regimen
• Carvedilol in Preventing Heart Failure in Childhood Cancer Survivors
• Inorganic Nitrite to Amplify the Benefits and Tolerability of Exercise Training in Heart Failure With Preserved Ejection Fraction (HFpEF) (INABLE-Training)
• Effect of W-3 Polyunsaturated Fatty Acids on Serum Albumin Concentration in Patients With Acute Heart Failure, Hypoalbuminemia, and High Inflammatory Activity
• A Study of CLR325 in Chronic Stable Heart Failure Patients.
• Safety, PK, and Efficacy of Omecamtiv Mecarbil in Japanese Subjects With Heart Failure With Reduced Ejection Fraction
• Effects of Metformin in Heart Failure Patients
• Estrogen Diastolic Heart Failure
• Description of Tolerability of LCZ696 (Sacubitril / Valsartan) in Heart Failure With Reduced Ejection Fraction (HFrEF) Treated in Real Life Setting
• Effect of Furosemide Withdraw in Stable Chronic Heart Failure Outpatients
• Catheter Ablation vs. Medical Therapy in Congested Hearts With AF
• Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of LCZ696 Followed by a 52-week Study of LCZ696 Compared With Enalapril in Pediatric Patients With Heart Failure
• An Exploratory Study of 18F-Labeled Hydroxyphenethylguanidines in Heart Failure Patients
• Splanchnic Nerve Anesthesia in Heart Failure
• Regional Tolvaptan Registry
• Comparison of Pre- and Post-discharge Initiation of LCZ696 Therapy in HFrEF Patients After an Acute Decompensation Event
• International Study to Determine if AdreView Heart Function Scan Can be Used to Identify Patients With Mild or Moderate Heart Failure (HF) That Benefit From Implanted Medical Device
• Follow-up Safety Trial in Children With Chronic Heart Failure Therapy Receiving Orodispersible Minitablets of Enalapril
• Dapagliflozin Effect on Symptoms and Biomarkers in Patients With Heart Failure
• Orodispersible Minitablets of Enalapril in Young Children With Heart Failure Due to Congenital Heart Disease
• Orodispersible Minitablets of Enalapril in Children With Heart Failure Due to Dilated Cardiomyopathy
• Effects of GLP-1 on Chronic Heart Failure
• Short-term Efficacy of Furosemide, Isosorbide Dinitrate and Their Combination in ADHF
• AiDing Diuresis wIth Tolvaptan (ADD-IT)
• The Safety and Efficacy of Tolvaptan for Patients With Tricuspid Regurgitation and Right Heart Failure After Left Heart Valves Replacement
• Loop Diuretic Dosage in Patients With Acute Heart Failure and Renal Failure: Conventional Versus Carbohydrate Antigen 125-guided Therapy (IMPROVE-HF)
• Intravenous Iron Treatment in Patients With Heart Failure and Iron Deficiency: IRONMAN
• Loop Diuretic Therapy in Acutely Decompensated Heart Failure
• GutHeart: Targeting Gut Microbiota to Treat Heart Failure
• Baroreflex Activation Therapy for Heart Failure
• Study of the Effect of Serelaxin on High-sensitivity Cardiac Troponin I (Hs-cTnI) Release in Patients With Chronic Heart Failure
• Metolazone As Early Add On Therapy For Acute Decompensated Heart Failure (MELT-HF)--A Single Center Pilot Study.
• Comparative Effects of Nebivolol and Carvedilol on Diastolic Function in the Elderly Heart Failure Patients
• The Clinical Study of the Safety and Efficacy of Istaroxime in Treatment of Acute Decompensated Heart Failure
• Comparison of Oral or Intravenous Thiazides vs Tolvaptan in Diuretic Resistant Decompensated Heart Failure
• Safety Study of Cenderitide in Chronic Stable Heart Failure With Moderate Renal Impairment
• Pharmacokinetics and Safety Study of Omecamtiv Mecarbil in Healthy Japanese Adults
• Indacaterol in Heart Failure Patients: Any Role on Lung Fluid Regulation
• Evaluation of Vepoloxamer in Chronic Heart Failure
• Glutamate for Metabolic Intervention in Coronary Surgery II
• Myocardial Perfusion, Oxidative Metabolism, and Fibrosis in HFpEF
• Mineralocorticoid Receptor Antagonists (MRA) in Heart Failure (HF) and Loop Diuretic Resistance
• Sub-Q Versus IV Furosemide in Acute Heart Failure
• Bioprofiling Response to Mineralocorticoid Receptor Antagonists for the Prevention of Heart Failure
• Comparison of Sacubitril/Valsartan Versus Enalapril on Effect on NT-proBNP in Patients Stabilized From an Acute Heart Failure Episode.
• Interleukin-1 Receptor Antagonist for the Treatment of Heart Failure in Patients With Left Ventricular Assist Devices
• Diagnosing and Targeting Mechanisms of Diuretic Resistance in Heart Failure
• Once-a-day Tacrolimus Conversion Study: The OneTAC Trial
• Digoxin Short Term Treatment Assessment Randomized Trial in AHF
• Biomarkers, Blood Pressure, BIS: Risk Stratification/Management of Patients at Cardiac Risk in Major Noncardiac Surgery
• Chronotropic Incompetence in Patients With HFpEF
• Pharmacodynamic and Pharmacokinetic Study of BiDil Extended-release Capsules and Commercial BiDil Tablets
• Comparative Study of Cardiac Adrenergic Function Explored by I-123-MIBG and CZT Camera (D-SPECT) Versus Anger Camera in Patients With Heart Failure
• The Transendocardial Autologous Cells (hMSC) or (hMSC) and (hCSC) in Ischemic Heart Failure Trial.
• RIGENERA 2.0 Trial
• A Study to Evaluate the Effect of the Transient Receptor Potential Vanilloid 4 (TRPV4) Channel Blocker, GSK2798745, on Pulmonary Gas Transfer and Respiration in Patients With Congestive Heart Failure
• Effects of Glucagon Like Peptide-1 on Haemodynamic Parameters
• Prevention of Hemorrhage After Implantation of Mechanical Circulatory Support
• Iloprost for Bridging to Heart Transplantation in PH
• Saxagliptin and Cardiac Structure and Function
• Tolvaptan For Worsening Outpatient Heart Failure: Role of Copeptin In Identifying Responders
• Study of Efficacy and Safety of LCZ696 in Japanese Patients With Chronic Heart Failure and Reduced Ejection Fraction
• A Study to Assess the Effect of Intravenous Dose of (aMBMC) to Subjects With Non-ischemic Heart Failure
• Ablation Verses Anti-arrhythmic Therapy for Reducing All Hospital Episodes From Recurrent Atrial Fibrillation
• Oral Nitrite for Older Heart Failure Patients
• Incretin-based Drugs and the Risk of Heart Failure
• The Use of Intranasal Fentanyl for the Treatment of Incident Dyspnea in Congestive Heart Failure: A Prospective Trial
• A Single-blind Pilot Study to Investigate Safety and Tolerability of the Chymase Inhibitor BAY1142524 in Clinically Stable Patients With Left-ventricular Dysfunction
• Influence of Edoxaban on Coagulability and Thrombin Generation: An in Vitro Study Focusing on Thrombelastography
• Effects of Ivabradine in Patients With Stable Coronary Artery Disease Without Clinical Heart Failure
• Effects of Ivabradine on Cardiovascular Events in Patients With Moderate to Severe Chronic Heart Failure and Left Ventricular Systolic Dysfunction. A Three-year International Multicentre Study
• Efficacy, Safety, and Tolerability of Perhexiline in Subjects With Hypertrophic Cardiomyopathy and Heart Failure
• High-Dose Aldactone for Treatment of Diuretic Resistant Heart Failure
• Mechanisms of Altered Ventilatory Control in Heart Failure
• Bone Marrow Derived Mesenchymal Stem Cells in Improving Heart Function in Patients With Heart Failure Caused by Anthracyclines
• Changes in Cardiac Deformation Following Physiologic Alterations and Inotropic Support.
• Safety and Effectiveness of SGLT-2 Inhibitors in Patients With Heart Failure and Diabetes
• Hospitalization & Mortality in Patients With Iron Deficiency CKD and HF Treated With i.v. Iron.
• Clinical Assessment of the Treatment With Cardiac Sympathetic Blockade on Chronic Heart Failure
• Multiple Patient Program to Ensure Access to LCZ696 Treatment to Patients Diagnosed With Heart Failure With Reduced Ejection Fraction (HF-rEF)
• A Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of Bendavia™ (MTP-131) in Patients With Heart Failure
• A Study Investigating the Safety, Tolerability, and Pharmacokinetics of MTP-131 in Subjects With Congestive Heart Failure
• Value of Renal Vascular Doppler Sonography in Management of Decompensated Heart Failure
• Safety & Efficacy of Intramyocardial Injection of Mesenchymal Precursor Cells on Myocardial Function in LVAD Recipients
• Safety Study of Cenderitide in Stable Chronic Heart Failure
• The Role of Chronotropic Incompetence in Heart Failure With Normal Ejection Fraction (HFNEF)
• Rhode Island Diastolic Dysfunction - Heart Failure
• Outcome and Treatment Quality Study of Tolvaptan to Treat Hyponatremia in Patients With Heart Failure
• HF Assessment With BNP in the Home: Part II
• Furosemide Pharmacodynamics and Pharmacokinetics After Subcutaneous or Oral Administration
• Efficacy and Mechanism of Exenatide on Improving Heart Function in Type 2 Diabetes With Heart Failure Patients
• Crossover Study to Compare the Pharmacokinetics and Bioavailability of a Novel Furosemide Regimen Administered Subcutaneously vs. the Same Dose Administered Intravenously in Subjects With Chronic Heart Failure
• Effects of Levothyroxine Supplementation in Patients With Systolic Heart Failure and Subclinical Hypothyroidism
• DPP-4 Inhibitor and Serum BNP Level of Diabetic Patients With Congestive Heart Failure
• Genomic Response Analysis of Heart Failure Therapy in African Americans
• Sildenafil in Heart Failure With Reactive Pulmonary Hypertension
• Early Aldosterone Blockade in Acute Heart Failure: An Exploratory Safety Study
• Effects of HTEA ON Heart Failure Secondary to Idiopathic Dilated Cardiomyopathy or Post-myocardial Infarction
• Cardioversion of Atrial Fibrillation Accompanied by Chronic Heart Faliure
• Spot Urinary Analysis to Assess Loop Diuretic Efficiency in Stable Heart Failure
• Regulation of Immunological Cytokines by Qiliqiangxin Capsule in Dilated Cardiomyopathy Patients
• Long-term Prednisone Use for End-stage Heart Failure
• Assessing the Safety and Bioactivity of SG1002 in Heart Failure Patients
• Levosimendan Administration and Outcome in Cardiac Surgery
• Intervention With Vitamin D and Omega-3 Supplements and Incident Heart Failure
• Inhaled Sodium Nitrite on Heart Failure With Preserved Ejection Fraction
• Levosimendan Efficacy Assessment by Cardiopulmonary Exercise Test (CPET)
• Pharmacokinetics, Pharmacodynamics, and Impact of Inorganic Nitrate on Exercise in HFpEF
• Relative Bioavailability Study With Enalapril in Healthy Volunteers
• The Influence of Heart Rate Limitation on Exercise Tolerance in Pacemaker Patients.
• Study of High Dosage of Losartan in Comparison to Low Dose of Losartan in Heart Failure Patients
• Dexamethasone Versus Prednisone in Heart Failure Patients, Hospitalized With Exacerbation of Chronic Obstructive Pulmonary Disease.
• The Use of Pramipexole and Other Dopamine Agonists and the Risks of Heart Failure and Pneumonia
• Control of Sinus Node Tachycardia as an Additional Therapy in Patients With Decompensated Heart Failure
• Study of High-dose Spironolactone vs. Placebo Therapy in Acute Heart Failure
• Biomarker Guided Therapies in Stage A/B Heart Failure
• Dental Anesthesia in Heart Failure Patients
• Safety and Tolerability During Open-label Treatment With LCZ696 in Patients With CHF and Reduced Ejection Fraction
• Pulmonary Arterial Denervation in Patients With Pulmonary Hypertension Associated With the Left Heart Failure
• Premature Fatigue in Veterans With Heart Failure: Neuronal Influences
• Systematic Withdrawal of Neurohumoral Blocker Therapy in Optimally Responding CRT Patients
• Oral Iron Repletion Effects On Oxygen Uptake in Heart Failure
• Clinical Trial of Systolic Heart Failure Treatment of IvabRadine Hemisulfate Sustained-release Tablets （FIRST）
• Aquaresis Utility for Hyponatremic Acute Heart Failure Study
• Interleukin-1 Blockade in HF With Preserved EF
• Ivabradine in Patients With an Unsatisfactory Percentage of Cardiac Resynchronization Therapy
• A Dose Ranging Phase IIa Study of 6 Hour Intravenous Dosages of CXL-1427 in Patients Hospitalized With Heart Failure
• Safety, Tolerability, Pharmacokinetic, Including Food Interaction, and Pharmacodynamic Profile of BIA 5-1058.
• Pharmacokinetics & Safety of Serelaxin on Top of Standard of Care Therapy in Pediatric Patients With Acute Heart Failure
• The Cardiac Insufficiency BIsoprolol Study in Japanese Patients With Chronic Heart Failure (CIBIS-J)
• A Study to Evaluate the Efficacy and Safety of Shenfu Zhusheye in Patients With Acute Heart Failure
• Levosimendan Versus Dobutamine for Renal Function in Heart Failure
• Prednisone for Heart Failure Patients With Hyperuricemia
• The Effect of Glucagon-Like Peptide-1 (GLP-1) on Pulmonary Vascular Resistance (PVR) in Patients With Heart Failure
• Contribution of Endothelin-1 to Exercise Intolerance in Heart Failure
• A First Time in Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GSK2798745 in Healthy Subjects and Stable Heart Failure Patients
• A Study of Rivaroxaban (JNJ-39039039) on the Venous Thromboembolic Risk in Post-Hospital Discharge Patients
• Investigator Initiated Randomized Open-label Comparative Study of Britomar (Prolonged Release Torasemide) and Diuver (Torasemide) to Assess Effects on Natriuresis and Central Hemodynamics.
• Iatrogenic Chronotropic Incompetence and Exercise Tolerance in Heart Failure
• Nebulized Inhaled Milrinone in a Hospitalized Advanced Heart Failure Population
• Effectiveness of a Diuretic Algorithm in Clinical Stability in Heart Failure Patients
• Effect of Serelaxin Versus Standard of Care in Acute Heart Failure (AHF) Patients
• Omega 3 for Treatment of Depression in Patients With Heart Failure
• Nitrate's Effect on Activity Tolerance in Heart Failure With Preserved Ejection Fraction
• Improving Treatment Personalization of Pulmonary Hypertension Associated With Diastolic Heart Failure
• A Prospective, Single-center, Randomized, Controlled, Open-label, Pilot Study to Compare the Effectiveness and Safety of DIuretics Add-On Strategy in Acute Decompensated Heart Failure Patients (DIOS II)
• Digoxin Versus Ivabradine in Heart Failure With Reduced Ejection Fraction
• 123I-mIBG SPECT Imaging
• Multiple Dose Study in Heart Failure of BAY 1067197
• Infusion Intracoronary of Mononuclear Autologous Adult no Expanded Stem Cells of Bone Marrow on Functional Recovery in Patients With Idiopathic Dilated Cardiomyopathy and Heart Failure.
• Evaluation of Cardiotoxic Effects of Bortezomib
• A Phase Ⅲ Study of Extended-Release Carvedilol Sulfate for the Treatment of Heart Failure
• Carbohydrate Antigen 125-guided Therapy in Heart Failure
• Efficacy, Safety and Tolerability of Sexelaxin When Added to Standard Therapy in AHF
• Study of Safety, Tolerability and Pharmacokinetics of Serelaxin in Japanese Acute Heart Failure (AHF) Patients
• Acute Effect of Pulmonary Desufflation on Cardiac Performance in COPD Patients
• The Role of Vitamin D in the Pathophysiology of Chronic Failure
• Safety of Repeat Doses of IV Serelaxin in Subjects With Chronic Heart Failure
• 0.5M Na Lactate Solution in Acute Heart Failure (AHF)
• Differential Gene Expression in Patients With Heart Failure and Iron Deficiency - Effects of Ferric Carboxymaltose
• Acetazolamide and Spironolactone to Increase Natriuresis in Congestive Heart Failure
• Genetically Targeted Therapy for the Prevention of Symptomatic Atrial Fibrillation in Patients With Heart Failure
• A Study to Explore the Efficacy of TRV027 in Patients Hospitalized for Acute Decompensated Heart Failure
• Phosphodiesterase Type 5 Inhibition With Tadalafil Changes Outcomes in Heart Failure: Extent of Renal Damage
• Pilot Study of Slow Release Oral Milrinone in Patients With Advanced Heart Failure
• Phase IIb Safety and Efficacy Study of BAY94-8862 in Subjects With Worsening Chronic Heart Failure and Left Ventricular Systolic Dysfunction and Either Type 2 Diabetes Mellitus With or Without Chronic Kidney Disease or Moderate Chronic Kidney Diseas
• Cardiovascular Improvements With MV ASV Therapy in Heart Failure
• Phase IIb Safety and Efficacy Study of Four Dose Regimens of BAY1021189 in Patients With Heart Failure and Preserved Ejection Fraction Suffering From Worsening Chronic Heart Failure (SOCRATES-PRESERVED)
• Phase IIb Safety and Efficacy Study of Four Dose Regimens of BAY1021189 in Patients With Heart Failure With Reduced Ejection Fraction Suffering From Worsening Chronic Heart Failure (SOCRATES-REDUCED)
• Acute Effects of Beet Juice Consumption on Exercise Capacity in Heart Failure
• Study to Assess the Safety of BAY1067197 in Stable Heart Failure Patients on Standard Therapy Including ß-blocker
• Influenza Vaccine To Prevent Adverse Vascular Events:Pilot
• A Double-Blind Pharmacokinetic Interaction Study Evaluating the Effect of a Single IV Infusion of GGF2 or Placebo on Midazolam Pharmacokinetics in Patients With Heart Failure
• Impacts of Aldosterone Blockade on Myocardial Remodeling in Hypertensive Patients With Diastolic Failing Heart
• The Impact of TORasemide oN hemodynAmic and Neurohormonal Stress, and carDiac remOdeling in Heart Failure
• Study on Reflex Response During Temporary Stimulation and Inhibition of Chemoreceptors of Carotid Bodies - a Pilot Study
• Traditional Chinese Medicine for Treatment of Chronic Heart Failure
• Interleukin-1 Blockade in Recently Decompensated Heart Failure
• Interleukin (IL)-1 Blockade in Acute Heart Failure (Anakinra ADHF)
• Open-label, Test-retest Study Assessing Reproducibility of Quantitative Measurements of Myocardial Uptake of AdreView.
• Sildenafil Impact on Ventricular Function in Patients With Heart Failure
• Safety and Efficacy of Doxycycline in Patients With Non-Ischemic Cardiomyopathy
• Acute Effects of Inorganic Nitrite on Cardiovascular Hemodynamics in Heart Failure With Preserved Ejection Fraction
• Outcome and Safety of Intermittent Dobutamine Infusion at a Day-Care Center in Advanced Heart Failure Patients
• Atorvastatin/CoenzymeQ10 in Congestive Heart Failure
• Short-Term Effects & Safety of an Accelerated Intravenous Iron Regimen in Patients With Heart Failure
• Pilot Study of Ferric Carboxymaltose to Treat Iron Deficiency in Asians With Heart Failure
• Safety and Tolerability of Initiating LCZ696 in Heart Failure Patients
• Protocolized Diuretic Strategy in Cardiorenal Failure
• Efficacy and Safety of LCZ696 Compared to Valsartan, on Morbidity and Mortality in Heart Failure Patients With Preserved Ejection Fraction
• Study of Efficacy and Safety of Percutaneous Coronary Intervention to Improve Survival in Heart Failure
• Muscle Afferent Feedback Effects in Patients With Heart Failure
• A Randomized Double-Blind, Placebo-Controlled, Multiple-Dose Study to Evaluate the Effects of Alagebrium on Exercise in Subjects With Diastolic Heart Failure
• Phosphodiesterase Type 5 Inhibition With Tadalafil Changes Outcomes in Heart Failure
• Diuretics and Dopamine in Heart Failure With Preserved Ejection Fraction
• The Use of Ranolazine for Atrial Fibrillation and Diastolic Heart Failure
• A Study to Assess the Effectiveness and Safety of Rivaroxaban in Reducing the Risk of Death, Myocardial Infarction or Stroke in Participants With Heart Failure and Coronary Artery Disease Following an Episode of Decompensated Heart Failure
• Beta 3 Agonist Treatment in Heart Failure
• Efficacy, Safety and Tolerability of Serelaxin When Added to Standard Therapy in AHF
• Effect of Ivabradine and Beta-blockers Combination Versus Beta-blockers Up-titration on Right Ventricular Pacing
• Tolvaptan/Ultrafiltration in the Treatment of Acute Heart Failure
• Study To Evaluate D-Ribose For The Treatment of Congestive Heart Failure
• Losartan in Decompensated Heart Failure
• Exercise Training and Testosterone Replacement in Heart Failure Patients
• Cardiac Resynchronization in Atrial Fibrillation Trial - a Pilot Study
• Evaluating the Safety, Pharmacokinetics and Haemodynamic Effect of a Slow Release Oral Formulation of Milrinone
• Omega-3 Fatty Acids in Elderly Patients With Acute Myocardial Infarction
• Comparison of Alcoholic Chlorhexidine 2% Versus Alcoholic Povidone Iodine for Infections Prevention With Cardiac Resynchronization Therapy Device Implantation
• Iron in Congestive Heart Failure
• Nesiritide and Renal Function After the Total Artificial Heart
• Bi Treatment With Hydralazine/Nitrates Versus Placebo in Africans Admitted With Acute Heart Failure
• Study to Compare the Pharmacokinetic Characteristics and Safety of Dilatrend SR Capsule 32mg and Dilatrend Tablet 25mg
• A Prospective, Single-center, Open-label, Pilot Study to Compare the Effectiveness and Safety of Diuretics Add-On Strategy in Chronic Heart Failure Patients (DIOS 1)
• Repurposing Probenecid as a Positive Inotrope for the Treatment of Heart Failure
• Benefit of the Treatment With Testosterone in Chronic Heart Failure Testosterone Deficiency Subjects
• Phase IIb Safety and Efficacy Study of Different Oral Doses of BAY94-8862 in Subjects With Worsening Chronic Heart Failure and Left Ventricular Systolic Dysfunction and Either Type 2 Diabetes Mellitus With or Without Chronic Kidney Disease or Chroni
• Functional Impact of GLP-1 for Heart Failure Treatment (FIGHT)
• A Study to Assess the Pharmacokinetics and Pharmacodynamics of JNJ-54452840 in Participants With Heart Failure and Anti-beta1-adrenergic Receptor Autoantibodies
• Digoxin Versus Ivabradine in Heart Failure With Preserved Systolic Function
• Study of the Acute Effects of Triheptanoin in Heart Failure
• COSMIC-HF - Chronic Oral Study of Myosin Activation to Increase Contractility in Heart Failure
• Statin Therapy In Atrial Refractoriness and Reperfusion Injury
• Remission From Stage D Heart Failure
• The Study to Evaluate Efficacy and Safety of Candesartan vs Losartan in Hypertension With Heart Failure (HONOR)
• Platelet Inhibition in Patients With Systolic Heart Failure
• The Role of Peritoneal Dialysis in Patients With Refractory Heart Failure and Chronic Kidney Disease
• Effects on Exercise Hemodynamics of Vasopressin Blockade by Conivaptan Infusion in Heart Failure Patients
• Safety Study of Chimeric Natriuretic Peptide(CD-NP) in Stable LVAD Patients
• Pharmacokinetics Study of AMG 423 in Healthy Subjects and Subjects With Various Degrees of Renal Insufficiency
• Evaluation of Cross-Linked Polyelectrolyte (CLP) With Placebo in Heart Failure Subjects
• Acute Heart Failure Patients With High Copeptin Treated With Tolvaptan Targets Increased AVP Activation for Treatment (ACTIVATE)
• Phase I Study of the Safety, Distribution, and Radiation Dosimetry of Ultratrace Iobenguane 123I-mIBG
• Sildenafil in HFpEF (Heart Failure With Preserved Ejection Fraction) and PH
• Carvedilol Effect in Preventing Chemotherapy - Induced Cardiotoxicity
• Inhaled Nitric Oxide and Inhaled Prostacyclin After Cardiac Surgery for Heart Transplant or LVAD Placement
• Efficacy Study of Digoxin & Ivabradine to Treat Heart Failure
• Cardioprotective and Metabolic Effects of Metformin in Patients With Heart Failure and Diabetes
• Dose Proportionality Study With BAY94-8862 IR (Immediate Release) Tablets
• To Evaluate the Efficacy and Safety on Blood Pressure In Patients With Hypertension Diagnosed Congestive Heart Failure
• The Use of Tolvaptan to Prevent Renal Dysfunction in High Risk Patients With Heart Failure-Pilot Study
• Efficacy and Safety of Ularitide for the Treatment of Acute Decompensated Heart Failure
• Clinical Assessment, Neuroimaging and Immunomarkers in Chagas Disease Study (CLINICS)
• Nebivolol for the Prevention of Left Ventricular Systolic Dysfunction in Patients With Duchenne Muscular Dystrophy
• Fatty Acid Radiotracer Comparison Study in Heart Failure Patients
• Safety and Efficacy of the Combination of Loop With Thiazide-type Diuretics in Patients With Decompensated Heart Failure
• Udenafil Therapy to Improve Symptomatology, Exercise Tolerance and Hemodynamics in Patients With Chronic Systolic Heart Failure
• Targeting Acute Congestion With Tolvaptan in Congestive Heart Failure
• THalidomide on Left ventricUlar Morphology aND Function in congEstive heaRt Failure
• Vitamin D3 Supplementation for Heart Failure Patients
• The Effects of Active VItamin D on Left Atrial Volume Index
• Recombinant BNP on Heart and Renal Function in Acute Heart Failure
• Efficacy and Safety of Tolvaptan in the Treatment of Cardiac-Induced Edema in Patients With Heart Failure
• Sildenafil Versus Placebo in Chronic Heart Failure
• Shensong Yangxin Capsule in the Treatment of Heart Failure Complicated With Ventricular Premature Beat
• Effect of Urocortins in Patients With Heart Failure
• A Randomized Trial of Udenafil Therapy in Patients With Heart Failure With Preserved Ejection Fraction [ULTIMATE-HFpEF]
• Evaluation of CLP With and Without Spironolactone in Heart Failure Patients With Chronic Kidney Disease
• Comparison of Eplerenone Versus Spironolactone in Heart Failure Patients With Glucose Intolerance or Type 2 Diabetes
• PAHTCH Pulmonary Arterial Hypertension Treatment With Carvedilol for Heart Failure (Carvedilol)
• Randomized, Double-Blind, Placebo Controlled Study of the Short Term Clinical Effects of Tolvaptan in Patients Hospitalized for Worsening Heart Failure With Challenging Volume Management
• The Clinical Study of the Efficacy and Safety of L-Carnitine Injection in Treatment of Heart Failure
• Long-Term Efficacy and Safety of Growth Hormone Replacement Therapy in Chronic Heart Failure
• A Pilot Study: Metformin Therapy in Heart Failure Patients With Early Diabetes or at High Risk of Developing Diabetes (Pre-Diabetes)
• Heart And Lung Failure - Pediatric INsulin Titration Trial
• Dose-comparison Study of Prednisone in Heart Failure
• A Study of MK-7145 in Participants With Renal Insufficiency (Part I) and Heart Failure With Renal Insufficiency (Part II) (MK-7145-011)
• A Randomized Trial of Carvedilol in Chronic Chagas Cardiomyopathy
• Clinical Assessment of Complementary Treatment With Qishen Yiqi Dripping Pills on Ischemic Heart Failure
• Polypharmacy in the Heart Failure Patient: Are All Prescribed Drug Classes Required? Statin Withdrawal Study
• Single Dose Study to Compare the Pharmacodynamics of Torasemide-PR 10 mg,Torasemide-IR 10 mg and Furosemide-IR 40 mg in Patients With Compensated Heart Failure
• Renal Hemodynamic Effects of RLX030A in Subjects With Chronic Heart Failure (CHF)
• Tadalafil and Nesiritide as Therapy in Pre-clinical Heart Failure
• Hemodynamic Responses to RLX030 Infusion in Subjects With Acute Heart Failure
• Pilot Feasibility Study of the Safety and Efficacy of Anakinra in Heart Failure With Preserved Ejection Fraction
• Study of the Survival of Recombinant Human Neuregulin-1β in Chronic Heart Failure (CHF) Patients
• Intermittent Intravenous Levosimendan in Ambulatory Advanced Chronic Heart Failure Patients
• Vitamine D Treatment in Chronic Heart Failure
• Supplementation of Glutamine and Fish Oil Versus Placebo in Patients With Heart Failure
• Aspirin Withdrawal in Non-ischaemic Cardiomyopathy Study
• Preoperative Parenteral Thiamine Supplementation in Patients Undergoing Heart Surgery
• Cardiac Resynchronisation Therapy and AV Nodal Ablation Trial in Atrial Fibrillation Patients (CAAN-AF)
• Cardiac Resynchronization and Iodine Meta-Iodobenzylguanidine (MIBG) Imaging
• Vasodilator Therapy for Heart Failure and Preserved Ejection Fraction
• Sugammadex and Heart Failure
• The Effects of Ranolazine on Exercise Capacity in Patients With Heart Failure With Preserved Ejection Fraction
• Effects of Atorvastatin Treatment on Left Ventricular Diastolic Function in Peritoneal Dialysis Patients
• A Pilot Study of Probiotic Saccharomyces Boulardii Use in Chronic Heart Failure Patients. Estudo PROICA
• Carvedilol Vascular Efficacy Trial
• Liothyronine and Heart Failure. The Long Term Effect of Liothyronine on Left Ventricular Ejection Fraction (LVEF)
• Effects of Cholecalciferol Supplementation in Patients With Chronic Heart Failure and LOw vITamind D Levels
• Feasibility and Effectiveness of Micronutrients as Palliative Care Therapy in Patients With Congestive Heart Failure
• Study of Heart Failure Hospitalizations After Aquapheresis Therapy Compared to Intravenous (IV) Diuretic Treatment
• The Effect of Liraglutide on Left Ventricular Function in Chronic Heart Failure Patients With and Without Type 2 Diabetes Mellitus
• BAROSTIM NEO System in the Treatment of Heart Failure
• The VO2 Increase With Testosterone Addition - Heart Failure (VITA-HF) Trial
• Effects of Apelin on the Lung Circulation in Pulmonary Hypertension
• Assessment of Coronary Flow Reserve in Heart Failure Patients After Ultrafiltration Versus Diuretics
• A Study to Compare the Use of Ferric Carboxymaltose With Placebo in Patients With Chronic Heart Failure and Iron Deficiency
• Risk Assessment and Comparative Effectiveness of Left Ventricular Assist Device (LVAD) and Medical Management
• Use of Beta-agonists in Stable Severe Congestive Heart Failure
• Study to Evaluate TRV120027 on Renal Pharmacodynamics in Patients With Heart Failure and Renal Dysfunction
• Loop Diuretics Administration and Acute Heart Failure
• Results of Tc99m-Maraciclatide Scintigraphy in Subjects With Diabetes Mellitus and Heart Failure With Preserved Left Ventricular Ejection Fraction
• Initial Study of Fenoterol as a Treatment for Heart Failure
• Study of Efficacy on Cardiac Remodeling of Recombinant Human Neuregulin-1 in Stable Chronic Systolic Heart Failure Patients
• Study of Efficacy on NT-proBNP of Recombinant Human Neuregulin-1 in Chronic Heart Failure Patients
• Effect of Tolvaptan on Mid- to Long-term Prognosis of Heart Failure Patients
• Evaluation of the Safety and Efficacy of Using Insulin-like Growth Factor-1 in Patients With a Heart Attack
• Is There a Benefit to Optimize Heart Failure (HF) Treatment in Aged Over 80 Year's Old Patients?
• Prevention of Cardiac Dysfunction During Adjuvant Breast Cancer Therapy
• Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care
• Inhaled Nitrite in Subjects With Pulmonary Hypertension
• Liraglutide and Heart Failure in Type 2 Diabetes
• Safety Study of Pyridostigmine in Heart Failure
• Evaluation of Enalapril Versus Placebo in Patients With Diastolic Heart Failure
• Catheter Ablation Versus Medical Treatment of AF in Heart Failure
• Effects of Chimeric Natriuretic Peptide Versus Placebo in Stable Heart Failure and Moderate Renal Dysfunction
• Digoxin Withdrawal in Stable Heart Failure
• Effect of Ferric Carboxymaltose on Exercise Capacity in Patients With Iron Deficiency and Chronic Heart Failure
• Pilot Study of COR-1 in Heart Failure
• Pilot Study of Vitamin D Supplementation in Heart Failure
• A Pharmacokinetic and Pharmacodynamic Study of Omecamtiv Mecarbil in Healthy Volunteers
• Predicting Successful Sleep Apnea Treatment With Acetazolamide in Heart Failure Patients
• Testosterone Therapy in Heart Failure
• Nebulized Albuterol for Congestive Heart Failure Exacerbation
• The Effects of Dobutamine on Postoperative Cardiac Function in Aortic Valve Replacement
• Heart Failure With Normal Ejection Fraction (HFNEF) in Hemodialysed Patients: Beneficial Effect of Ivabradine
• Feasibility of an Integrated Patient Care (IPC) System Using Daily Filling Pressures
• A Multi-center, Placebo-controlled Study to Evaluate the Safety of GSK716155 and Its Effects on Myocardial Metabolism, Myocardial Function, and Exercise Capacity in Patients With NYHA Class II/III Congestive Heart Failure
• Reduced Contractile Reserve: a Therapeutic Target in Heart Failure With Preserved Ejection Fraction(HFpEF)
• Sodium Excretion of LCZ696 in Patients With Hypertension; Heart Failure and Healthy Volunteers
• Pharmacologic Reversal of Ventricular Remodeling in Childhood Cancer Survivors at Risk for Congestive Heart Failure (PREVENT-CHF): A Phase IIB Randomized Placebo-Controlled Trial
• Pilot Study of Using Copeptin to Predict Response to Tolvaptan
• BAY94-8862 Dose Finding Trial in Subjects With Chronic Heart Failure and Mild (Part A) or Moderate (Part B) Chronic Kidney Disease
• Effects of Pentoxiphylline on Left Ventricular (LV) Systolic Function Indices and Circulating Biomarkers in Patients With Chronic Congestive Heart Failure (CHF)
• Vitamin D and Mortality in Heart Failure
• Lung Impedance Monitoring In Treatment of Chronic Heart Failure
• A Comparison of Dilute Versus Concentrated Heparin for CRRT Anticoagulation
• PK/PD Study of Subcutaneous Cenderitide Infusion in CHF Patients
• A Randomized, Controlled Study to Evaluate Algisyl-LVR™ as a Method of Left Ventricular Augmentation for Heart Failure
• Efficacy and Safety of Levosimendan in Severe Acute Heart Failure in Critical Children
• Pilot Study of the Safety and Efficacy of Anakinra (Recombinant Human Interleukin-1 Receptor Antagonist) in Heart Failure
• Study to Evaluate the Safety and Efficacy of IV Infusion Treatment With Omecamtiv Mecarbil in Subjects With Left Ventricular Systolic Dysfunction Hospitalized for Acute Heart Failure (ATOMIC-AHF)
• Significance of Regional Ventriculo-arterial Coupling in Patients With Chronic Heart Failure
• Effects of Urocortins on Forearm Arterial Blood Flow in Healthy Volunteers - Protocol 4
• Study of Qiliqiangxin Capsule to Treat Dilated Cardiomyopathy
• Vitamin D Supplementation in Chronic Stable Heart Failure
• ELEVATE Early LEvosimendan Vs Usual Care in Advanced Chronic hearT failurE
• Extended Drug Utilization Study Among Patients Exposed to Ticagrelor, Clopidogrel and Prasugrel
• Bosentan for Severe Mitral Valve Dysfunction
• Evaluation of CLP in Heart Failure Patients With Chronic Kidney Disease
• Mechanisms of Improvement With Beta-Blocker Treatment in Heart Failure
• Single Ascending Doses of GGF2 in Patients With Left Ventricular Dysfunction and Symptomatic Heart Failure
• Blood Pressure Reduction in Heart Failure
• Safety Study of GE-145 320 mg I/mL Injection vs. Iopamidol 370 mg I/mL in Elderly Subjects Undergoing Coronary Procedure
• Efficacy and Safety of Human Neuregulin-1 to Treat Stable Chronic Heart Failure
• Treatment of the lOw IGF-1 Syndrome aSsociated With Chronic Heart fAilure: A Randomized, Placebo-Controlled, Double-Blind Study.
• Vitamin D Supplementation for Treatment of Heart Failure
• PUFAs and Left Ventricular Function in Heart Failure
• Inotropic Treatment With Levosimendan (SimdaxR)in Heart Surgery
• Metformin to Reduce Heart Failure After Myocardial Infarction
• Ranolazine Implantable Cardioverter-Defibrillator Trial
• Clinical Trial to Evaluate the Efficacy and Safety of Recombinant Human Neuregulin-1 for Subcutaneous Administration in Patients With Chronic Systolic Heart Failure
• Safety and Efficacy of Furosemide 40mg + Amiloride Hydrochloride 10mg to Reduct Edema
• Study to Evaluate the Effects of TRV120027 in Patients With Heart Failure
• Exercise Oscillatory Breathing and Sildenafil in Heart Failure
• Physiological Effects of Grape Seed Extract in Diastolic Heart Failure
• Spanish Atrial Fibrillation And Resynchronization Study
• Investigating the Inotropic Potential of Apelin
• Heart Rate Reduction in Heart Failure
• Anakinra to Prevent Adverse Post-infarction Remodeling (2)
• Ranolazine in Diastolic Heart Failure
• Donor Simvastatin Treatment in Organ Transplantation
• Diastolic Heart Failure Management by Nifedipine
• Phosphodiesterase-5 (PDE5) Inhibition and Pulmonary Hypertension in Diastolic Heart Failure
• Significance of Regional Ventriculo-arterial Coupling in Patients With Chronic Heart Failure
• REWORD-HF REverse WOrsening Renal Function in Decompensated Heart Failure
• Cardiorenal Interactions During Treatment of Acute Decompensated Heart Failure: Diuretics Versus Ultrafiltration
• Renal Optimization Strategies Evaluation in Acute Heart Failure and Reliable Evaluation of Dyspnea in the Heart Failure Network (ROSE) Study
• Study of the Survival of Recombinant Human Neuregulin-1β in Chronic Heart Failure (CHF) Patients
• Evaluation of Patiromer Titration in Heart Failure Patients With Chronic Kidney Disease
• Study to Evaluate the Effectiveness of High Dose Statin Loading in Acute Heart Failure Patients
• A Study to Investigate the Pharmacodynamic and Pharmacokinetic Interaction Between Aliskiren and Furosemide in Patients With Heart Failure
• Peritoneal Dialysis in Congestive Heart Failure
• Neurostimulation of Spinal Nerves That Affect the Heart
• Management of Diabetes With Metformin In Patients With Chronic Heart Failure
• A Study to Investigate the Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of an Intravenous Solution of JNJ-39588146 or Placebo in Patients With Heart Failure
• Clinical Study Of Eplerenone In Japanese Patients With Chronic Heart Failure
• Thiamine Supplementation in Heart Failure Patients Receiving Full Medical Therapy
• Association Between Genetic Polymorphism of Beta-adrenergic Receptor and Effects of Bisoprolol in Korean Heart Failure Patients.
• The Impact of Pomegranate Extract on Chronic Cardiomyopathy Complicated by Renal Insufficiency (ImPrOVE): a Pilot Study
• Targeting Sympathetic Overactivity in Heart Failure Patients With Statins
• A Dose-Defining Study of CXL-1020 in Patients With Systolic Heart Failure
• Safety and Hemodynamic Effects and Pharmacokinetics of CXL-1020 in Patients With Stable Heart Failure
• Study to Investigate the Effects of Vitamin D Administration on Plasma Renin Activity in Patients With Stable Chronic Heart Failure
• Trial to Determine Imaging Parameters of LMI1195 in Heart Failure Patients at Low and High Risk of Defibrillator Firing
• Regulatory Nebilet PMS
• Pharmacokinetic Study of Omecamtiv Mecarbil in Heart Failure Patients
• A Prospective, Open-labeled, Multi-centric Trial in Subjects With Systolic Heart Failure to Evaluate Bisoprolol Treatment for the Effects on Surrogate Markers of Heart Failure in Korea
• The Effect of Hyperglycemia on LV Function and Exercise Capacity in Diabetics With and Without Heart Failure.
• Spironolactone in Adult Congenital Heart Disease
• Anti-Hypertensive Agent (ACEi) and Heart Function Improvement in Association With Rho Kinase Activity Changes in Human
• A Phase IIb Study to Investigate the Efficacy and Tolerability of Lower Doses Cinaciguat (25 µg/h, 10 µg/h) Given Intravenously to Patients With Acute Decompensated Chronic Congestive Heart Failure (ADHF)
• Efficacy and Safety of Pulsed Infusions of Levosimendan in Outpatients With Advanced Heart Failure
• BAY58-2667 Dose Finding Trial Investigating Fixed Doses in Patients With Acute Decompensated Chronic Congestive Heart Failure (ADHF)
• A Phase IIb Study to Investigate the Efficacy and Tolerability of Cinaciguat (150 µg/h, 100 µg/h, 50 µg/h) Given Intravenously to Subjects With Acute Decompensated Chronic Congestive Heart Failure (ADHF)
• Dopamine in Acute Decompensated Heart Failure II
• Study to Evaluate the Effects of Oral Administration of Lixivaptan in Patients With Congestive Heart Failure
• SIDAMI - Sildenafil and Diastolic Dysfunction After Acute Myocardial Infarction (AMI)
• Safety, Pharmacokinetic and Pharmacodynamic Study of COR-1, an Anti-ß1 Receptor Antibody Cyclopeptide
• The Hemodynamic Response to Prolonged Dobutamine Infusion
• Add-on Aliskiren Treatment in Patients With Chronic Congestive Heart Failure
• This Study Will Evaluate the Efficacy and Safety of LCZ696 Compared to Enalapril on Morbidity and Mortality of Patients With Chronic Heart Failure
• Safety and Efficacy of Low Dose Hypertonic Saline Solution and High Dose Furosemide for Congestive Heart Failure
• Preoperative Levosimendan and Heart Failure
• Multidisciplinary Approach to Novel Therapies in Cardiology Oncology Research
• Digoxin Dosing in Heart Failure: A Simplified Nomogram Versus Standard Care
• Micronutrient Supplementation in Patients With Heart Failure
• Allopurinol in Chronic Heart Failure
• Long-Term Intermittent Administration of Levosimendan in Patients With Advanced Heart Failure
• Using Allopurinol to Relieve Symptoms in Patients With Heart Failure and High Uric Acid Levels
• The Effects of Decreasing the Lasix Dose on the Cardiorenal System
• Effects of Aliskiren on Patient With Heart Failure and a Normal Ejection Fraction
• Chronic Sildenafil Treatment in Heart Failure
• Low Dose Intravenous (IV) Infusion of BNP in the Presence and Absence of Acute Type V Phosphodiesterase (PDE V) in Improving Renal Function in Hospitalized Chronic Heart Failure (CHF) Patients With Renal Dysfunction
• Cardiovascular Magnetic Resonance for the Occluded Infarct-Related Artery Treatment
• Assessing the Safety/Efficacy of Transdermal Testosterone in Female Patients With Symptomatic Heart Failure
• The Effects of Glucocorticoids on Mortality and Renal Function in Patients With Acute Decompensated Heart Failure
• The Effect of Omega-3 Polyunsaturated Fatty Acids in Congestive Heart Failure
• Pharmacokinetics of Oral CK-1827452 in Patients With Stable Heart Failure
• Dopamine in Acute Decompensated Heart Failure (DAD-HF) Trial
• Effect of Intramyocardial Injection of Mesenchymal Precursor Cells on Heart Function in People Receiving an LVAD
• Effects of Nebivolol Versus Carvedilol on Cardiopulmonary Function at High Altitude in Healthy Subjects.
• Comparing the Effects of Conivaptan and Diuretics on Plasma Neurohormones and Renal Blood Flow in Patients With Chronic Congestive Heart Failure
• Effects of Aliskiren, Ramipril, and the Combination on Levels of Angiotensin II in Patients With Decompensated Systolic Heart Failure
• Prednisone for Heart Failure Patients With Hyperuricemia
• Safety/Tolerability, Pharmacokinetics/Pharmacodynamics (PK/PD) of LCZ696 in Patients With Stable Heart Failure
• Oral Metolazone and Intermittent Intravenous Furosemide Versus Continuous Infusion Furosemide in Acute Heart Failure
• Investigating Systemic and Local Vascular Responses to Apelin in the Context of Renin-angiotensin Upregulation
• Effect of Vildagliptin on Left Ventricular Function in Patients With Type 2 Diabetes and Congestive Heart Failure
• Six Months Efficacy and Safety of Aliskiren Therapy on Top of Standard Therapy, on Morbidity and Mortality in Patients With Acute Decompensated Heart Failure
• A Phase 1 Trial to Determine Dosimetry, Biodistribution and Safety of LMI 1195-101 in Healthy Subjects and Patients With Heart Failure
• LCZ696 Compared to Valsartan in Patients With Chronic Heart Failure and Preserved Left-ventricular Ejection Fraction
• Ability of Metoprolol to Alter the Exercise Induced Elevation of Catecholamines
• Safety and Efficacy Study of Add On Aliskiren in Patients With Heart Failure and Renal Impairment
• Catheter Ablation Versus Medical Rate Control for Atrial Fibrillation in Patients With Heart Failure
• International, Multicenter, Open-Label and Randomized Withdrawal Study of Oral Lixivaptan in Heart Failure Patients With Chronic Hyponatremia
• Melatonin Supplementation to Improve Sleep in Patients With Heart Failure
• Phase I Interaction Study of Istaroxime and Digoxin in Subjects With Stable Heart Failure
• Evaluation of Patiromer in Heart Failure Patients
• Hemodynamic Effects of Spironolactone in Patients With Heart Failure
• Using Clonidine to Improve Leg Weakness in People With Heart Failure
• Efficacy and Safety of Aliskiren and Aliskiren/Enalapril Combination on Morbidity-mortality in Patients With Chronic Heart Failure
• Nicorandil Study to Reduce Cardiac Death After Percutaneous Coronary Intervention (PCI) in Hemodialysis Patients
• Safety and Efficacy of Conivaptan in Hyponatremic Patients With Symptomatic Acute Decompensated Heart Failure (ADHF)
• Efficacy of Candesartan on Brain Natriuretic Peptide Levels in Subjects With Chronic Heart Failure
• Assessment of Biomarkers and Cardiorenal Syndrome in Acute Decompensated Heart Failure With Vasodilator Therapy
• Metabolic Manipulation in Chronic Heart Failure
• Safety and Efficacy Trial to Treat Diastolic Heart Failure Using Ambrisentan
• Perhexiline Therapy in Heart Failure With Preserved Ejection Fraction Syndrome
• Study to Assess the Safety and Efficacy of CD-NP in the Treatment of Patients With Acute Decompensated Heart Failure
• Safety and Efficacy Study of Istaroxime in Acute Decompensated Heart Failure Patients
• Cognitive Impairment in Patients With Heart Failure
• Collaborative Systematic Overview of Randomised Controlled Trials of Beta-Blockers in the Treatment of Heart Failure
• Water- and Salt-homeostasis in Healthy Humans, and in Patients With Heart- or Lung Disease
• EFfect of Ferric Carboxymaltose on exercIse CApacity and Cardiac Function in Patients With Iron deficiencY and Chronic Heart Failure
• Safety and Efficacy of Bosentan in Patients With Diastolic Heart Failure and Secondary Pulmonary Hypertension
• Study of Low Dose Nesiritide With or Without Sildenafil in Congestive Heart Failure Patients With Renal Dysfunction
• An Open-label, One-arm, Study to Evaluate the Hemodynamic Changes and Safety of Nesiritide for Acute Decompensated Heart Failure
• Glycemic Control and Variability for Congestive Heart Failure Exacerbation
• Intensive Glycemic Control for Congestive Heart Failure Exacerbation
• Body Volume Regulation in Pulmonary Arterial Hypertension With Right Ventricular Failure
• Diuretic and Renal Effects of Vaprisol When Administered Along With Furosemide and Nesiritide Continuous Infusion
• Clevidipine in the Treatment of Blood Pressure in Patients With Acute Heart Failure (PRONTO)
• Pharmacodynamic Study of Carvedilol Versus Metoprolol in Heart Failure
• Evaluating the Use of Exenatide in People With Type 2 Diabetes and Diastolic Heart Failure
• A Study Of The Usage Of Statins In A Community Heart Failure Population
• Evaluation of Sildenafil for the Treatment of Moderate Congestive Heart Failure
• The Effect of GHRH Therapy on Myocardial Structure and Function in Congestive Heart Failure
• The Effect of Glucose-Insulin-Potassium Infusion in Patients Undergoing Cardiac Surgery
• AC6 Gene Transfer for CHF
• Effects of Viagra on Heart Function in Patients With Heart Failure
• Efficacy of Candesartan on Symptomatic Heart Failure in Treating Diabetic and Hypertensive Patients.
• Aliskiren and Renin Inhibition in Diastolic Heart Failure
• Thiamine Supplementation to Improve Cardiac Function in Patients With Congestive Heart Failure
• The Effect of Simvastatin Therapy on the Expression of Procoagulant and Inflammatory Markers in Heart Failure
• Effects of Exenatide in Type 2 Diabetic Patients With Congestive Heart Failure
• Evaluating the Effectiveness of Sildenafil at Improving Health Outcomes and Exercise Ability in People With Diastolic Heart Failure (The RELAX Study)
• METhotrexate Therapy Effects in the Physical Capacity of Patients With ISchemic Heart Failure (METIS Trial)
• If Channel Blockade With Ivabradine in Patients With Diastolic Heart Failure
• Compassionate Use Study of 125 mg Per Day of Azimilide Dihydrochloride in One Patient
• Phase II Study of the Effect of CK-1827452 Injection on Myocardial Efficiency
• Bone Marrow Derived Adult Stem Cells for Chronic Heart Failure
• Buspirone as a Potential Treatment for Recurrent Central Apnea
• Oral Tonapofylline (BG9928) in Patients With Heart Failure and Renal Insufficiency
• Safety and Efficacy Study to Evaluate the Effect of SLV320 on Renal Function in Patients With Worsening Heart Failure
• A Phase I/II Clinical Study of SK&F-105517-D in Japanese Patients With Chronic Heart Failure
• Safety & Efficacy of ALT-711 (Alagebrium) in Chronic Heart Failure
• A Randomized, Placebo-Controlled, Double-Blind, Double Dummy Trial To Determine The Relative Effect Of Pm101 Versus Placebo And Amiodarone IV On Blood Pressure In Subjects With Stable Congestive Heart Failure
• Ablation vs Amiodarone for Treatment of AFib in Patients With CHF and an ICD
• Hemodynamic Effects of Rolofylline in the Treatment of Patients With Heart Failure (7418-503)
• Phase 2b Study to Assess the Safety and Tolerability of IV Tonapofylline in Subjects With Acute Decompensated Heart Failure (ADHF) and Renal Insufficiency
• Bisoprolol in Patients With Heart Failure and Chronic Obstructive Pulmonary Disease
• South Korean Pitavastatin Heart Failure Study
• Study to Assess Hemodynamic Effects, Safety and Tolerability of Chimeric Natriuretic Peptide (CD-NP) in Patients With Stabilized Acute Heart Failure (AHF)
• Influence of Pantoprazole on Human Myocardial Contractility at Patients With Congestive Heart Failure
• European Trial of Dronedarone in Moderate to Severe Congestive Heart Failure
• The Impact of Zinc Supplementation on Left Ventricular Function in Nonischemic Cardiomyopathy
• Evaluation of the Effect of AVE0657 in Cheynes-Stokes Breathing Syndrome Patients
• N-3 Fatty Acids for the Prevention of Atrial Fibrillation in Patients With Acute Heart Failure
• A Comparison of Hydrochlorothiazide and Metolazone in Combination With Furosemide in Congestive Heart Failure Patients
• PK and Tolerability of IV and Oral CK-1827452 in Patients With Ischemic Cardiomyopathy and Angina
• Thiamine and Acute Decompensated Heart Failure: Pilot Study
• Observational Usage and Efficacy Study of Candesartan in Heart Failure Treatment in France
• Study to Demonstrate the Non-inferiority of Olmesartan Medoxomil Versus Candesartan Cilexetil in Reducing Blood B-type (or Brain) Natriuretic Peptide Levels at Week 24
• Spironolactone and Insulin Resistance in Chronic Heart Failure (CHF)
• Effects of Losartan on Insulin Resistance in Patients With Heart Failure
• Effects of Spironolactone on Matrix Metalloproteinases (MMPs) in Heart Failure
• Beginning a Randomized Evaluation of the AGE Breaker Alagebrium in Diastolic Heart Failure (BREAK-DHF-I)
• IVIg Therapy for Patients With Idiopathic Cardiomyopathy and Endomyocardial Biopsy Proven High PVB19 Viral Load
• Study of the Effect of Sitagliptin on Glucose (Sugar) Metabolism in Patients With Heart Failure
• Evaluation of the Effects of Urotensin-II and Soluble Epoxide Hydrolase Inhibitors on Skin Microvessel Tone in Patients With Heart Failure, and in Healthy Volunteers
• Clinical Study to Evaluate Nesiritide in Patients Undergoing Coronary Artery Bypass Graft (CABG) Surgery A014 / NAPA
• Effects of MK7418 on Diuresis and Renal Function in Congestive Heart Failure Patients
• Evaluation of Combined Action Between Natrecor and Furosemide on Kidney and Neurohormone Responses in Chronic Heart Failure: A Phase-IV study704.351 / DSS
• Candesartan Cilexetil in Heart Failure Assessment of Reduction in Mortality and Morbidity (CHARM Preserved)
• Candesartan in Heart Failure Assessment of Reduction in Mortality and Morbidity (CHARM Alternative)
• Candesartan Cilexetil in Heart Failure Assessment of Reduction in Mortality and Morbidity (CHARM Added)
• A Study of CK-1827452 Infusion in Stable Heart Failure
• CD-NP in Subjects With Stable Chronic Heart Failure
• A Phase II Trial to Assess Hemodynamic Effects of Istaroxime in Pts With Worsening HF and Reduced LV Systolic Function
• The Effects of Carperitide on Short and Long-term Prognosis in Patients With Both Cardiac and Renal Failure
• Alprostadil Continuous Intravenous Infusion in Bridging Cardiac Transplant in Severe Heart Failure Patients
• Effectiveness of Ultrafiltration in Treating People With Acute Decompensated Heart Failure and Cardiorenal Syndrome (The CARRESS Study)
• Effectiveness of Surgical Mitral Valve Repair Versus Medical Treatment for People With Significant Mitral Regurgitation and Non-ischemic Congestive Heart Failure
• Effects of Pyruvate in Patients With Cardiogenic Shock and Intra-aortic Balloon Counterpulsation
• SCREEN-HFI (SCReening Evaluation of the Evolution of New Heart Failure Intervention Study)
• Growth Hormone Deficiency in Chronic Heart Failure: A Preliminary Trial
• AV Node Ablation and Pacemaker Therapy Compared to Drug Therapy for Atrial Fibrillation - Pilot Study
• Effects of Statin Therapy on Vascular Properties and Outcomes in Diastolic Heart Failure Patients
• Harefield Recovery Protocol Study for Patients With Refractory Chronic Heart Failure
• Vascular Effects of Sertraline in Heart Failure
• Myocardial Hemodynamic Effects of Levosimendan
• The Development of Tolerance to α1-Adrenoceptor Blockade With Chronic Carvedilol Treatment
• Determining Optimal Dose and Duration of Diuretic Treatment in People With Acute Heart Failure (The DOSE-AHF Study)
• Concentrated Saline Infusions and Increased Dietary Sodium With Diuretics for Heart Failure With Kidney Dysfunction
• Effect of Ranolazine on Echocardiographic Indices of Diastolic Dysfunction
• Effect of Aldosterone on Energy Starvation in Heart Failure
• Study to Evaluate the Effect of SLV320 in Addition to Chronic Furosemide Treatment on Renal Function in Subjects With Congestive Heart Failure and Impaired Renal Function
• Single Dose Escalation Study in Patients With Chronic Heart Failure
• Nt-proBNP Guided Primary Prevention of CV Events in Diabetic Patients
• Role of Natriuretic Peptides in the Treatment of Acutely Decompensated Heart Failure Patient With Obstructive Airways Disease
• Placebo Controlled, Randomized, Double-blind, Multi-center Study to Investigate the Efficacy and Tolerability of BAY58-2667
• Impact of Nesiritide Infusion for Decompensated Heart Failure in the Emergency Department
• Safety Study of CD-NP in Heart Failure
• Hypertonic Saline Solution in Heart Failure
• Changes of Left Ventricular Mass and Cardiac Function in Patients With Active Acromegaly During Treatment With the Growth Hormone Receptor Antagonist Pegvisomant
• Does Ascorbic Acid Reduce Sympathoexcitation in CHF?
• Effect of 4 Weeks Treatment With Acipimox in Patients With Chronic Heart Failure
• A Study of OPC-41061 in Subjects With Cardiac-induced Edema (Congestive Heart Failure)
• A Study of Iron Oligosaccharide in CHF Patients
• Investigation of the Safety and Feasibility of AAV1/SERCA2a Gene Transfer in Patients With Chronic Heart Failure
• An Exploratory Sub-study for the RED-HF™ (Reduction of Events With Darbepoetin Alfa in Heart Failure) Trial
• N-Acetylcysteine in Heart Failure With Coexistent Chronic Renal Failure
• An Efficacy and Safety Study for Nesiritide in Heart Failure Patients With Reduced Kidney Function Undergoing Coronary Artery Bypass Graft Surgery Requiring Cardiopulmonary Bypass (CPB Pump or Heart Lung Machine)
• Renal Effects of Levosimendan in Patients Admitted With Acute Decompensated Heart Failure
• Tezosentan in Acute Heart Failure
• A Clinical Pharmacological Study of OPC-41061 in the Treatment of Cardiac Edema (Congestive Heart Failure)
• Standard Drug Therapy vs. Implanted Defibrillator for Primary Prevention of Sudden Cardiac Death
• Tezosentan in the Treatment of Acute Heart Failure
• Aldosterone Blockade in Heart Failure
• Safety Comparison of Pioglitazone and Glyburide in Type 2 Diabetes Subjects With Mild to Moderate Congestive Heart Failure
• Efficacy and Safety of Relaxin for the Treatment of Acute Heart Failure
• Ferinject® Assessment in Patients With Iron Deficiency and Chronic Heart Failure (FAIR-HF)
• Nebivolol Versus Bisoprolol Versus Carvedilol in Heart Failure
• Effects of Acetazolamide and CO2 Inhalation on Exercise-induced Periodic Breathing in Heart Failure
• The BENEFICIAL Study: Evaluating the Efficacy and Safety of Alagebrium (ALT-711) in Patients With Chronic Heart Failure
• Preventing Contrast Nephropathy With Sodium Bicarbonate in Patients With Pulmonary Edema,Heart Failure,Uncontrolled HTN
• Goal-directed Afterload Reduction in Acute Congestive Cardiac Decompensation Study
• Testosterone Improves Exercise Oxygen Uptake, Insulin Resistance and Muscle Strength in Elderly Patients With Chronic Heart Failure
• Double Blind Randomized Placebo Controlled Trial of Natrecor in Acute Decompensated Heart Failure With Normal EF
• The Effect of Eplerenone and Atorvastatin on Markers of Collagen Turnover in Diastolic Heart Failure
• Effects of Growth Hormone on Exercise Capacity
• The Effect of Calcium and Vitamin D in Patients With Heart Failure
• Effect of Beta Blocker Treatment on Endothelial Function in Patients With Type 2 Diabetes or Chronic Heart Failure
• Effect of Folic Acid on Endothelial and Baroreceptor Function in Patients With Heart Failure
• Telmisartan in Haemodialysis Patients With Chronic Heart Failure
• An Exploratory Study of Nesiritide in Participants With Acute Heart Failure
• A Study of Ularitide in the Treatment of Subjects With Acute Decompensated Heart Failure
• Safety and Pharmacodynamic Study of CD-NP
• Effects of Allopurinol on Diastolic Function in Chronic Heart Failure Patients
• A Study Testing the Effectiveness of Nesiritide in Patients With Acute Decompensated Heart Failure
• Metformin in Insulin Resistant Left Ventricular (LV) Dysfunction (TAYSIDE Trial)
• A Double-blind, Placebo-controlled Study of OPC-41061 in the Treatment of Cardiac Edema (Congestive Heart Failure)
• A Comparative Study of Aleglitazar and Actos in Patients With Type 2 Diabetes Mellitus and New York Heart Association (NYHA) Class II Heart Failure.
• BNP Therapy Observation Unit Outcomes STudy (BOOST)
• Metabolic Modulation as Treatment in Acute Heart Failure
• Placebo-Controlled Randomized Study of KW-3902 for Subjects Hospitalized With Worsening Renal Function and Heart Failure Requiring IV Therapy
• BOAT: Beta Blocker Uptitration With OptiVol After Cardiac Resynchronization Therapy (CRT)
• Treatment of Hyperuricemia in Patients With Heart Failure
• A Clinical Study Assessing the Potential of Piboserod for the Treatment of Heart Failure
• Erythropoietin Treatment in Patients With Systolic Left Ventricular Dysfunction, Mild Anemia and Normal Renal Function
• Supplemental Benefit of Angiotensin Receptor Blocker in Hypertensive Patients With Stable Heart Failure Using Olmesartan
• Effect of a New Formulation of Torasemide (Prolonged Release)on Myocardial Fibrosis in Patients With Heart Failure.
• PDE5-Inhibition With Sildenafil in Chronic Heart Failure
• Recombinant Human Relaxin for the Treatment of Decompensated CHF
• Human B-type Natriuretic Peptide (BNP) (Nesiritide) to Help Heart, Kidney, and Hormonal Functions in Persons With Lower Heart Pumping Function
• Antiremodeling Effect Of Aldosterone Receptors Blockade With Canrenone In Mild Chronic Heart Failure. AREA IN-CHF Study
• Evaluation of Myocardial Improvement in Patients Supported by Ventricular Assist Device Under Optimal Pharmacological Therapy
• A Pharmacogenomic Study of Candesartan in Heart Failure
• Evaluation of Heart Failure Treatment Guided by N-terminal Pro B-type Natriuretic Peptide (NTproBNP) vs Clinical Symptoms and Signs Alone
• Natriuretic Peptide System as Therapy in Human Preclinical Left Ventricle Dysfunction
• Iron Supplementation in Heart Failure Patients With Anemia: The IRON-HF Study
• Intravenous Iron in Patients With Severe Chronic Heart Failure and Chronic Kidney Disease
• A Comparison of the Effect of Carvedilol and Metoprolol on Airways Tone in Patients With Heart Failure
• Prospective Evaluation of Elastic Restraint to LESSen the Effects of Heart Failure (PEERLESS-HF) Trial
• Effects of Carvedilol on Health Outcomes in Heart Failure
• Therapy With Verapamil or Carvedilol in Chronic Heart Failure
• Bumetanide Versus Furosemide in Heart Failure
• Prednisone for Decompensated Congestive Heart Failure
• Heart Failure and Peritoneal Ultrafiltration
• Study of Anginera in Adults With a Left Ventricular Assist Device (LVAD) as Bridge to Transplant
• Influence of Angiotensin Converting Enzyme (ACE) Genotype on Lung Diffusion in Heart Failure
• RED-HF™ Trial - Reduction of Events With Darbepoetin Alfa in Heart Failure Trial
• Mechanisms of Erythropoietin Action in the Cardiorenal Syndrome
• Comparison of Long- and Short-acting Diuretics in Congestive Heart Failure
• PROTECT-2: A Study of the Selective A1 Adenosine Receptor Antagonist KW-3902 for Patients Hospitalized With Acute HF and Volume Overload to Assess Treatment Effect on Congestion and Renal Function
• Capturing Outcomes of Clinical Activities Performed by a Rounding Pharmacist Practising in a Team Environment
• Use of Nesiritide (BNP) in Kidney Function in Patients With Congestive Heart Failure (CHF) and Kidney Failure
• Carvedilol Versus Verapamil in Chronic Heart Failure Secondary to Non-Ischemic Cardiomyopathy
• Survival of Patients With Acute Heart Failure in Need of Intravenous Inotropic Support: a Multicentre, Parallel-Group, Randomised, Double-Blind, Double-Dummy Study of Levosimendan Versus Dobutamine in Patients With Acute Heart Failure.
• Effect of Irbesartan on Insulin Sensitivity in Chronic Heart Failure
• Effects of Acute L-NMMA Treatment on Renal Hemodynamics and Vasoactive Hormones in Patients With Congestive Heart Failure
• Organized Program To Initiate Lifesaving Treatment In Hospitalized Patients With Heart Failure (OPTIMIZE-HF)
• Hawthorn Extract Randomized Blinded Chronic Heart Failure (HERB CHF) Trial
• Natrecor (Nesiritide) in Transplant-Eligible Management of Congestive Heart Failure-TMAC
• GISSI-HF- Effects of n-3 PUFA and Rosuvastatin on Mortality-Morbidity of Patients With Symptomatic CHF
• The Effect of Ribose on B-Type Natriuretic Peptide (BNP) Levels in Congestive Heart Failure Patients
• Spironolactone Safety in Dialysis Patients
• PROTECT-1: A Study of the Selective A1 Adenosine Receptor Antagonist KW-3902 for Patients Hospitalized With Acute HF and Volume Overload to Assess Treatment Effect on Congestion and Renal Function
• Patients With Heart Failure ANd Type 2 Diabetes Treated With Placebo Or Metformin (PHANTOM) Pilot Study
• Levosimendan in Acute Heart Failure Following Acute Myocardial Infarction.
• Chagas Cardiomyopathy Bisoprolol Intervention Study: Charity
• A Study to Compare the Effects of Coreg CR and Coreg IR on Heart Function in Subjects With Stable Chronic Heart Failure
• Effect Of GW501516X On How The Heart Obtains And Uses Energy
• Study of Nesiritide in Diastolic Heart Failure.
• Study of Sildenafil in Patient With Heart Failure.
• Study of Sildenafil in Advanced Heart Failure.
• A Study of the Effectiveness of Sitaxsentan Sodium in Patients With Diastolic Heart Failure
• A Study of Valsartan Administered Once Daily Versus Twice Daily, in Patients With Stable, Chronic Heart Failure
• Reversing Endothelial and Diastolic Dysfunction and Improving Collagen Turnover in Diastolic Heart Failure
• Curing Atrial Fibrillation in Heart Failure
• A Study of Two Doses of Intravenous NATRECOR hBNP (Nesiritide) in Patients With Worsening Congestive Heart Failure Who Have Difficulty Breathing at Rest
• Extracorporeal Ultrafiltration (UF) vs. Usual and Customary Care for Patients With Severe Heart Failure (HF)
• Anemia in Heart Failure With a Preserved Ejection Fraction (HFPEF)
• Ursodeoxycholic Acid in Chronic Heart Failure
• ZP120 Add-on to Furosemide in Treatment of Acute or Sub-Acute Decompensated Heart Failure
• Intravenous Allopurinol to Improve Heart Function in Individuals With Dilated Cardiomyopathy
• DILIPO (DILutIonal HyPOnatremia)
• Drug Compliance and Quality of Life in Patients With Heart Failure Dosed With Either Once-daily or Twice-daily Coreg
• A Study to Develop Additional Safety and Clinical Experience With NATRECOR hBNP (Nesiritide) in the Treatment of Patients With Worsening Congestive Heart Failure Who Require Inpatient Intravenous Therapy With Medications That Influence the Tone and
• Renal Effects of Intrarenal Nesiritide
• A Safety Study Comparing Natrecor (Nesiritide) Versus Dobutamine Therapy for Worsening Congestive Heart Failure
• A Study of Short-Term Outcomes and Economic Impact For Patients With Worsening Congestive Heart Failure When Natrecor (Nesiritide) is Added to Standard-Care Therapy, Compared to Administration of Placebo With Standard-Care Therapy
• A Study Comparing Blood Flow and Clinical and Safety Effects of the Addition of Natrecor (Nesiritide), Placebo or Intravenous Nitroglycerin to Standard Care for the Treatment of Worsening Congestive Heart Failure.
• FUSION I Assesses Safety and Tolerability of Two Doses of NATRECOR (Nesiritide) Administered to Patients With Worsening Congestive (Decompensated) Heart Failure Who Are Concurrently Receiving Their Usual Cardiac Medications and Are at High Risk for
• Effect of 48 Hours of Treatment With the Natural Peptide-Hormone GLP-1 in Patients With Chronic Heart Failure
• Diuretic Efficacy of Dexamethasone in Heart Failure
• A Pilot Study of Recombinant Human Relaxin (rhRlx) in Compensated Congestive Heart Failure
• Evaluation of the Effects of Carperitide in Patients With Congestive Heart Failure
• Cardiac Hormone Replacement With Brain Natriuretic Peptide (BNP) in Heart Failure
• Ability of L-carnitine to Prevent Heart Damage in Breast Cancer Patients Receiving Anthracycline Chemotherapy
• The VALIDATE Study of Valsartan for Patients With Early Stage Heart Failure
• Rosuvastatin Impact on Ventricular Remodelling Lipids and Cytokines
• Nesiritide and Vo2 Max in Heart Failure Patients
• A Dose-finding Study of OPC-41061 in Treatment of Cardiac Edema (Congestive Heart Failure)
• Statin Therapy in Heart Failure: Potential Mechanisms of Benefit
• A Comparison Of Outcomes In Patients In New York Heart Association (NYHA) Class II Heart Failure When Treated With Eplerenone Or Placebo In Addition To Standard Heart Failure Medicines
• Dutch Sub Study: Controlled Rosuvastatin Multinational Study in Heart Failure (CORONA). PET Sub Study
• Efficacy and Safety of Treatment With Simdax® Versus Dobutrex® in Decompensated Heart Failure Patients.
• "ALOFT - Aliskiren Observation of Heart Failure Treatment": Efficacy and Safety of Aliskiren Added on Top of Standard Therapy in Adults (≥ 18 Years) With Stable Heart Failure
• Beta-2 Polymorphisms and Beta Receptor Selectivity
• Crestor Versus Placebo in Subjects With Heart Failure
• Novel Treatment for Diastolic Heart Failure in Women
• Catheterization Laboratory Study: Acute Responses in Diastolic Heart Failure
• Efficacy and Safety of Ivabradine in Severe Congestive Heart Failure
• BNP for Cardio-Renal Decompensation Syndrome (BNP-CARDS)
• Evaluation of the Effect of Human Recombinant Growth Hormone in Patients With Advanced Heart Failure
• Intravenous Allopurinol in Heart Failure
• Impact of Rosuvastatin on Endothelial Function and Inflammation in Patients With Chronic Heart Failure
• Efficacy and Safety of Valsartan Versus Placebo on Exercise Tolerance in Patients With Heart Failure
• Brain Natriuretic Peptide (BNP) to Preserve Renal Function in Hospitalized Patients With Heart Failure
• Study of Blood Concentrations and Physiologic Effects of Levosimendan Given During Heart Surgery
• Effects of Nesiritide in Pediatric Patients With Heart Failure
• Beta-Blocker Continuation Versus Interruption in Heart Failure Worsening
• Study to Evaluate Cardiac Hemodynamics and Safety of SLV320 in Subjects With Congestive Heart Failure
• Dose Escalation Study of KW-3902 on Diuresis in Subjects With Congestive Heart Failure (CHF).
• Effect of KW-3902IV in Combination With IV Furosemide on Renal Function in Subjects With CHF and Renal Impairment
• Phase 1 Safety and Pharmacokinetic Study of AI-700 in Patients With Diminished DLCO and COPD and/or CHF
• Levosimendan in High Risk Heart Valve Surgery
• Effects of Amlodipine in the Management of Chronic Heart Failure
• Add-on Effects of Valsartan on Morbi- Mortality (KYOTO HEART Study)
• Nesiritide in Chronic Heart Failure
• A Morbidity-Mortality and Remodeling Study With Valsartan
• Heart Pressure Assessment Study With Tolvaptan to Treat Congestive Heart Failure
• The Effect of Alfa-Adrenergic Receptor Blockade on Insulin-Stimulated Forearm Glucose Uptake and Metabolism in Chronic Heart Failure
• Peroral Levosimendan in Chronic Heart Failure
• Study to Evaluate the Safety of Twice Daily Oral Carvedilol
• Meta-Iodobenzylguanidine (123I-mIBG) Scintigraphy Imaging in Patients With Heart Failure and Control Subjects Without Cardiovascular Disease
• Meta-Iodobenzylguanidine Scintigraphy Imaging in Patients With Heart Failure and Control Subjects Without Cardiovascular Disease
• Effect of Intravenous Ferrous Sucrose on Exercise Capacity in Chronic Heart Failure
• Larger Dose of Spironolactone for the Treatment of Patients With Nonischemic Cardiomyopathy
• Ultrafiltration Versus Intravenous (IV) Diuretics for Patients Hospitalized for Acute Decompensated Heart Failure: (UNLOAD)
• PIE II: Pharmacological Intervention in the Elderly II
• COREG MR Versus TOPROL-XL On Reduction Of Microalbuminuria In Patients With Hypertension And Microalbuminuria
• Nesiritide Infusion for the Treatment of Decompensated Heart Failure and Renal Dysfunction
• A Study of Repeat-Dose Subcutaneous Darbepoetin Alfa in Subjects With Congestive Heart Failure and Anemia, and a Single Dose in Healthy Age- and Sex-Matched Control Subjects
• Impact of Darbepoetin Alfa on Exercise Tolerance and Left Ventricular Structure in Subjects With Symptomatic Congestive Heart Failure (CHF) and Anemia
• Trial Assessing the Effect of Preoperative Furosemide on Intraoperative Blood Pressure
• Angiotensin Converting Enzyme Inhibition in Children With Mitral Regurgitation
• Trial of Angiotensin Converting Enzyme Inhibition in Infants With Single Ventricle--Pediatric Heart Network
• Aldosterone Antagonism in Diastolic Heart Failure
• Study of DITPA in Patients With Congestive Heart Failure
• Study to Examine the Safety and Effectiveness of Implanted Skeletal Muscle Cells (Cells Removed From the Thigh Muscle) Into Scarred Areas of Heart Muscle After Heart Attack.
• PROCLAIM: Effect of AC2592 Administered by Continuous Subcutaneous Infusion in Subjects With Advanced Chronic Congestive Heart Failure
• Irbesartan in Heart Failure With Preserved Systolic Function (I-Preserve)
• A Fish Oil Supplement to Maintain Body Weight in Patients With Disease-Related Weight Loss
• Aldosterone Antagonist Therapy for Adults With Heart Failure and Preserved Systolic Function
• A Study of the Safety and Efficacy of Follow-up Serial Infusions of Natrecor(Nesiritide) for the Management of Patients With Heart Failure
• IMMEDIATE Trial - Out of Hospital Administration of Glucose, Insulin and Potassium.
• Study to Evaluate Potential Decrease in Hospitalization Events, Time Between Events, and Increasing Longevity in Patients With Symptomatic Heart Failure (0954-948)
• Subcutaneous (SC) Darbepoetin Alfa in Subjects With Symptomatic Congestive Heart Failure (CHF) & Anemia
• Use of Nesiritide in the Management of Acute Diastolic Heart Failure
• The Purpose of This Study is to Determine if Eplerenone is Effective in Treatment of Mild to Moderate Heart Failure
• Antidepressant Medication Treatment for Depression in Individuals With Chronic Heart Failure
• Enoximone Plus Extended-Release Metoprolol Succinate in Subjects With Advanced Chronic Heart Failure
• Dobutamine Echocardiography In Patients With Ischemic Heart Failure Evaluated for Revascularization
• EVEREST: Efficacy of Vasopressin Antagonism in hEart failuRE: Outcome Study With Tolvaptan
• Study of Oral PG-116800 Following a Heart Attack
• Rosiglitazone to Treat Patients With Heart Failure and Glucose Intolerance or Type II Diabetes
• Oxypurinol Compared With Placebo for Class III-IV NYHA Congestive Heart Failure
• The Effects of Nitric Oxide for Inhalation During Left Ventricular Assists Device (LVAD) Implantation
• Safety and Efficacy Study of YM087 (Conivaptan) in Patients With Acute Decompensated Heart Failure
• MYOHEART™ (Myogenesis Heart Efficiency and Regeneration Trial)
• Safety and Efficacy Study of Carvedilol to Treat Children With Congestive Heart Failure
• ESSENTIAL-"The Studies of Oral Enoximone Therapy in Advanced Heart Failure"
• Autologous Cultured Myoblasts (BioWhittaker) Transplanted Via Myocardial Injection
• Safety and Efficacy Study of Once and Twice Daily Doses of MCC-135 in Subjects With Congestive Heart Failure.
• Heart Failure and Anemia
• Evaluation of Intravenous Levosimendan Efficacy in the Short Term Treatment of Decompensated Chronic Heart Failure.
• African-American Heart Failure Trial
• The DIAMOND Study: Distensibility Improvement And Remodeling in Diastolic Heart Failure
• Study to Compare the Effects of Two Dosages of Tolvaptan in Congestive Heart Failure Patients
• Multicenter, Randomized, Double-Blind, Placebo Controlled, Efficacy Study on the Effects of Tolvaptan on Left Ventricular Dilatation in Congestive Heart Failure Patients
• Estrogen, Cytokines and Heart Failure in Women
• Reversal of Ventricular Remodeling With Toprol-XL
• Safety Study of Vasopressin V2 Receptor Antagonist on Patients With Severe Chronic Heart Failure (AQUAVIT).
• A Thyroid Hormone Analog to Fight Heart Failure: Phase II Trial (DITPA)
• Comparison of Surgical and Medical Treatment for Congestive Heart Failure and Coronary Artery Disease
• Warfarin and Antiplatelet Therapy in Chronic Heart Failure
• Occluded Artery Trial (OAT)
• The Role of Angiotensin Type I Receptor in the Regulation of Human Coronary Vascular Function
• The Role of Angiotensin Type I Receptor in the Regulation of Human Peripheral Vascular Function
• Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT)
• Beta-Blocker Evaluation in Survival Trial (BEST)
• Enalapril After Anthracycline Cardiotoxicity
• Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)
• Studies of Left Ventricular Dysfunction (SOLVD)
• Digitalis Investigation Group (DIG)